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PPP3CB (NM_021132) Human Untagged Clone
CAT＃: SC112977
PPP3CB (untagged)-Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2
CNY 3,912.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CALNA2; CALNB; CNA2; PP2Bbeta |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_021132, the custom clone sequence may differ by one or more nucleotides
ATGGCCGCCCCGGAGCCGGCCCGGGCTGCACCGCCCCCACCCCCGCCCCCGCCGCCCCCTCCCGGGGCTG ACCGCGTCGTCAAAGCTGTCCCTTTCCCCCCAACACATCGCTTGACATCTGAAGAAGTATTTGATTTGGA TGGGATACCCAGGGTTGATGTTCTGAAGAACCACTTGGTGAAAGAAGGTCGAGTAGATGAAGAAATTGCG CTTAGAATTATCAATGAGGGTGCTGCCATCCTTCGGAGAGAGAAAACCATGATAGAAGTAGAAGCTCCAA TCACAGTGTGTGGTGACATCCATGGCCAATTTTTTGATCTGATGAAACTTTTTGAAGTAGGAGGATCACC TGCTAATACACGATACCTTTTTCTTGGCGATTATGTGGACAGAGGTTATTTTAGTATAGAGTGTGTCTTA TATTTATGGGTTCTGAAGATTCTATACCCAAGCACATTATTTCTTCTGAGAGGCAACCATGAATGCAGAC ACCTTACTGAATATTTTACCTTTAAGCAGGAATGTAAAATTAAGTATTCGGAAAGAGTCTATGAAGCTTG TATGGAAGCTTTTGATAGTTTGCCTCTTGCTGCACTTTTAAACCAACAGTTTCTTTGTGTTCATGGTGGA CTTTCACCAGAAATACACACACTGGATGATATTAGGAGATTAGATAGATTCAAAGAGCCACCTGCATTTG GACCAATGTGTGACTTGTTATGGTCCGATCCTTCTGAAGATTTTGGAAATGAAAAATCACAGGAACATTT TAGTCACAATACAGTTCGAGGATGTTCTTATTTTTATAACTATCCAGCAGTGTGTGAATTTTTGCAAAAC AATAATTTGTTATCGATTATTAGAGCTCATGAAGCTCAAGATGCAGGCTATAGAATGTACAGAAAAAGTC AAACTACAGGGTTCCCTTCATTAATAACAATTTTTTCGGCACCTAATTACTTAGATGTCTACAATAATAA AGCTGCTGTATTAAAGTATGAAAATAATGTGATGAATATTCGACAGTTTAACTGTTCTCCACATCCTTAC TGGTTGCCTAATTTTATGGATGTCTTCACGTGGTCTTTACCGTTTGTTGGAGAAAAAGTGACAGAAATGT TGGTAAATGTTCTGAGTATTTGCTCTGATGATGAACTAATGACTGAAGGTGAAGACCAGTTTGATGGTTC AGCTGCAGCCCGGAAAGAAATCATAAGAAACAAAATTCGAGCAATTGGCAAGATGGCAAGAGTCTTCTCT GTTCTCAGGGAGGAGAGTGAAAGTGTGCTGACACTCAAGGGCCTGACTCCCACAGGGATGTTGCCTAGTG GAGTGTTAGCTGGAGGACGGCAGACCCTGCAAAGTGCCACAGTTGAGGCTATTGAGGCTGAAAAAGCAAT ACGAGGATTCTCTCCACCACATAGAATCTGCAGTTTTGAAGAGGCAAAGGGTTTGGATAGGATCAATGAG AGAATGCCACCTCGGAAAGATGCTGTACAGCAAGATGGTTTCAATTCTCTGAACACCGCACATGCCACTG AGAACCACGGGACGGGCAACCATACTGCCCAGTGA >OriGene 5' read for NM_021132 unedited
NGGGGTCGAATATTTGTATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGAAGC CGAGCCCCGGGCCCAGCATGGCCGCCCCGGAGCCGGCCCGGGCTGCACCGCCCCCACCCC CGCCCCCGCCGCCCCCTCCCGGGGCTGACCGCGTCGTCAAAGCTGTCCCTTTCCCCCCAA CACATCGCTTGACATCTGAAGAAGTATTTGATTTGGATGGGATACCCAGGGTTGATGTTC TGAAGAACCACTTGGTGAAAGAAGGTCGAGTAGATGAAGAAATTGCGCTTAGAATTATCA ATGAGGGTGCTGCCATCCTTCGGAGAGAGAAAACTATGATAGAAGTAGAAGCTCCAATCA CAGTGTGTGGTGACATCCATGGCCAATTTTTTGATCTGATGAAACTTTTTGAAGTAGGAG GATCACCTGCTAATACACGATACCTTTTTCTTGGCGATTATGTGGACAGAGGTTATTTTA GTATAGAGTGTGTCTTATATTTATGGGTTCTGAAGATTCTATACCCAAGCACATTATTTC TTCTGAGAGGCAACCATGAATGCAGACACCTTACTGAATATTTTACCTTTAAGCAGGAAT GTAAAATTAAGTATTCGGAAAGAGTCTATGAAGCTTGTATGGAAGCTTTTGATAGTTTGC CTCTTGCTGCACTNTTAAACCAACAGTTTCTTTGTGTTCATGGTGGACTCTCACCAGAAA TACACACACTGGATGATATTAGGAGATTAGATAGATTCAAAGAGCCACCTGCATTTGGAC CAATGTGTGACTTGTTATGGTCCGATCCTTTCTGAGATTTGGAAATGAANAATCACAGGA CATTTTAGTCCAATACAGTTCGAGGAGTTCCTATTTTTATACTATCCAGCAGGGTGTGAA TT >OriGene 3' read for NM_021132 unedited
CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGGAGCAGCGGCCCATGCA TGGAATTTATTGTGTGCTACTGTTTATAAAATACTCGAATAGTCCTGCACATGCATAATA TTTCCAACTTAGACAGGAGACCATACAGGGTGCACTTTCTGGCAAACAAAACAATAGATG GTTCCGCTGCCTGGAGCTCTGAGTTGTATTCCAGGGCATGAGGGAAGCAGGCCACCAAAG TAAAGGGAAATACCAAACTACAGTGGCAATCAATACAGGTCAATAATTGTGAAAAATTAG CACATGGTTCCATTTAGTTTAACCAAGCAGTTCAGTAACTATCAAAAGAAAGGTTTCAAC ATGCAGTCTTGACTTTTATGCTTCCACTAACATCTGAATGATTGAACAGAACCATTGCTT CTAGGCTGCATTGCTTAATCAAAAACACTTCCAGAACATTTTAAAATTTCCTTTGCATTA AAACATAAAAATGATAGAAAGCCAGCAGCAAATCACCCTGGTGGCTCTCTAAGCAACTTG AGTACTCACAATAAACTAAAATTTCTCATAACATCTAGGTAACCTATACATGTCGTACCT GTACATCATAGGTCTATATATTAAATATTTGCAAAATGAAAACATGCATACACAAAATAC GTCAAGTTTACAGACATGACTTGAATTAAAATTTACTTTGACAATGTACAAACTTCTTTT AAAGTACCTTAAATGAGCAAATTCTGTAATTCTTCATTAATTTGAAAATTTAGAGGTTTT CTTTTTTAAATCTCTTGGGTGTAAGGCCTTAAAGAAATGGGCCCAAAAAAACTCTAATTA ACTTTTGGGCTTGCGTTCAAGTAAGAAAACCTGCCTGAAAATAGGATTCCTTTCTTATTA AAAAATCCCCACTTTGTCCCAAATACCCCCTTTAG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_021132 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021132.1, NP_066955.1 |
| RefSeq Size | 3079 bp |
| RefSeq ORF | 1575 bp |
| Locus ID | 5532 |
| UniProt ID | P16298 |
| Domains | Metallophos, PP2Ac |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway |
| Gene Summary | Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals (PubMed:19154138, PubMed:26794871). Dephosphorylates and activates transcription factor NFATC1 (PubMed:19154138). Dephosphorylates and inactivates transcription factor ELK1 (PubMed:19154138). Dephosphorylates DARPP32 (PubMed:19154138).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. It encodes isoform b which is shorter than isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206982 | PPP3CB (Myc-DDK-tagged)-Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2 |
CNY 3,912.00 |
|
| RC206982L1 | Lenti ORF clone of Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2, Myc-DDK-tagged |
CNY 6,312.00 |
|
| RC206982L2 | Lenti ORF clone of Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC206982L3 | Lenti ORF clone of Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206982L4 | Lenti ORF clone of Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG206982 | PPP3CB (tGFP-tagged) - Human protein phosphatase 3, catalytic subunit, beta isozyme (PPP3CB), transcript variant 2 |
CNY 4,370.00 |
