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LYAR (NM_017816) Human Untagged Clone
CAT＃: SC113969
LYAR (untagged)-Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ZC2HC2; ZLYAR |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_017816, the custom clone sequence may differ by one or more nucleotides
ATGGTATTTTTTACATGCAATGCATGTGGTGAATCAGTGAAGAAAATACAAGTGGAAAAGCATGTGTCTG TTTGCAGAAACTGTGAATGCCTTTCTTGCATTGACTGCGGTAAAGATTTCTGGGGCGATGACTATAAAAA CCACGTGAAATGCATAAGTGAAGATCAGAAGTATGGTGGCAAAGGCTATGAAGGTAAAACCCACAAAGGC GACATCAAACAGCAGGCGTGGATTCAGAAAATTAGTGAATTAATAAAGAGACCCAATGTCAGCCCCAAAG TGAGAGAACTTTTAGAGCAAATTAGTGCTTTTGACAACGTTCCCAGGAAAAAGGCAAAATTTCAGAATTG GATGAAGAACAGTTTAAAAGTTCATAATGAATCCATTCTGGACCAGGTGTGGAATATCTTTTCTGAAGCT TCCAACAGCGAACCAGTCAATAAGGAACAGGATCAACGGCCACTCCACCCAGTGGCAAATCCACATGCAG AAATCTCCACCAAGGTTCCAGCCTCCAAAGTGAAAGACGCCGTGGAACAGCAAGGGGAGGTGAAGAAGAA TAAAAGAGAAAGAAAGGAAGAACGGCAGAAGAAAAGGAAAAGAGAAAAGAAAGAACTAAAGTTAGAAAAC CACCAGGAAAACTCAAGGAATCAGAAGCCTAAGAAGCGCAAAAAGGGACAGGAGGCTGACCTTGAGGCTG GTGGGGAGGAAGTCCCTGAGGCCAATGGCTCTGCAGGGAAGAGGAGCAAGAAGAAGAAGCAGCGCAAGGA CAGCGCCAGTGAGGAAGAGGCACGCGTGGGCGCAGGGAAGAGGAAGCGGAGGCACTCGGAAGTTGAAACA GATTCTAAGAAGAAAAAGATGAAGCTCCCAGAGCATCCTGAGGGCGGAGAACCAGAAGACGATGAGGCTC CTGCAAAAGGTAAATTCAACTGGAAGGGAACTATTAAAGCAATTCTGAAACAGGCCCCAGACAATGAAAT AACCATCAAAAAGCTAAGGAAAAAGGTTTTAGCTCAGTACTACACAGTGACAGATGAGCATCACAGATCC GAAGAGGAACTCCTGGTCATCTTTAACAAGAAAATCAGCAAGAACCCTACCTTTAAGTTATTAAAGGACA AAGTCAAGCTTGTGAAATGA >OriGene 5' read for NM_017816 unedited
ACTATAGGGGGCGGCCGCGTAATTCGGCACGAGGCCGCGCCCGAGCGGACTGCGGGGCGC CCCTGCGGCCCGGGCCCGCCGCGCGGACCAGCCCCAACTGAGCGGGAGCGAAAGCGGCGG CGGCCTCCGGCTCAGACGCAAAGTTCGCTGCCTTCCATTGGAGTGACTGAATTTCTACAT GACGGCTTTTTGACAAGACTTAAAACCTGTCTTGGATAGAGAATATTTAGCCATTTACCT AAAAATGGTATTTTTTACATGCAATGCATGTGGTGAATCAGTGAAGAAAATACAAGTGGA AAAGCATGTGTCTGTTTGCAGAAACTGTGAATGCCTTTCTTGCATTGACTGCGGTAAAGA TTTCTGGGGCGATGACTATAAAAACCACGTGAAATGCATAAGTGAAGATCAGAAGTATGG TGGCAAAGGCTATGAAGGTAAAACCCACAAAGGCGACATCAAACAGCAGGCGTGGATTCA GAAAATTAGTGAATTAATAAAGAGACCCAATGTCAGCCCCAAAGTGAGAGAACTTTTAGA GCAAATTAGTGCTTTTGACAACGTTCCCAGGAAAAAGGCAAAATTTCATAATTGGATGAA GAACAGTTTAAAAGTTCATAATGAATCCATTCTGGACCAGGTGTGGAATATCTTTTCTGA AGCTTCCAACAGCGAACCAGTCAATAATGAACAGGATCAACGGCCACTTCACCCATCGGC AAATCCACATGCAGAAAATCTCCACCAAGTTTCCAGCCTCCAAAGTGAAAGACGCCCTGG TACAGCNAGGGGATGGTGAAGATAATTAAACCATAATGATGGGAGTACCGGCCNAAGAAA GGAAAAGAGAAAAGAAAGAACCTAAGTTTGTAAACCCCCAGCAAAACTCTAGGGATCCGA GCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017816 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_017816.1, NP_060286.1 |
| RefSeq Size | 1598 bp |
| RefSeq ORF | 1140 bp |
| Locus ID | 55646 |
| UniProt ID | Q9NX58 |
| Gene Summary | Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227). Also acts at the level of transcription regulation. Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918). In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580). Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918). Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells (By similarity). Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201908 | LYAR (Myc-DDK-tagged)-Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1 |
CNY 3,656.00 |
|
| RC201908L1 | Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201908L2 | Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201908L3 | Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201908L4 | Lenti ORF clone of Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG201908 | LYAR (tGFP-tagged) - Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1 |
CNY 4,370.00 |
|
| SC322377 | LYAR (untagged)-Human Ly1 antibody reactive homolog (mouse) (LYAR), transcript variant 1 |
CNY 3,656.00 |
