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SAMHD1 (NM_015474) Human Untagged Clone
CAT＃: SC114650
SAMHD1 (untagged)-Human SAM domain and HD domain 1 (SAMHD1)
CNY 4,672.00
| Cited in 7 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CHBL2; DCIP; HDDC1; hSAMHD1; MOP-5; SBBI88 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114650 sequence for NM_015474 edited (data generated by NextGen Sequencing)
ATGCAGCGAGCCGATTCCGAGCAGCCCTCCAAGCGTCCCCGTTGCGATGACAGCCCGAGA ACCCCCTCAAACACCCCTTCCGCAGAGGCAGACTGGTCCCCGGGCCTGGAACTCCATCCC GACTACAAGACATGGGGTCCGGAGCAGGTGTGCTCCTTCCTCAGGCGCGGTGGCTTTGAA GAGCCGGTGCTGCTGAAGAACATCCGAGAAAATGAAATCACAGGCGCATTACTGCCTTGT CTTGATGAGTCTCGTTTTGAAAATCTTGGAGTAAGTTCCTTGGGGGAGAGGAAGAAGCTG CTTAGTTATATCCAGCGATTGGTTCAAATCCACGTTGATACAATGAAGGTAATTAATGAT CCTATCCATGGCCACATTGAGCTCCACCCTCTCCTCGTCCGAATCATTGATACACCTCAA TTTCAACGTCTTCGATACATCAAACAGCTGGGAGGTGGTTACTATGTTTTTCCAGGAGCT TCACACAATCGATTTGAGCATAGTCTAGGGGTGGGGTATCTAGCAGGATGTCTAGTTCAC GCACTGGGTGAAAAACAACCAGAGCTGCAGATAAGTGAACGAGATGTTCTCTGTGTTCAG ATTGCTGGACTTTGTCATGATCTCGGTCATGGGCCATTTTCTCACATGTTTGATGGACGA TTTATTCCACTTGCTCGCCCGGAGGTGAAATGGACGCATGAACAAGGCTCAGTTATGATG TTTGAGCACCTTATTAATTCTAATGGAATTAAGCCTGTCATGGAACAATATGGTCTCATC CCTGAAGAAGATATTTGCTTTATAAAGGAACAAATTGTAGGACCACTTGAATCACCTGTC GAAGATTCATTGTGGCCATATAAAGGGCGTCCTGAAAACAAAAGCTTCCTTTATGAGATA GTATCTAATAAAAGAAATGGCATTGATGTGGACAAATGGGATTATTTTGCCAGGGACTGC CATCATCTTGGAATCCAAAATAATTTTGATTACAAGCGCTTTATTAAGTTTGCCCGTGTC TGTGAAGTAGACAATGAGTTGCGTATTTGTGCTAGAGATAAGGAAGTTGGAAATCTGTAT GACATGTTCCACACTCGCAACTCTTTACACCGTAGAGCTTATCAACACAAAGTTGGCAAC ATTATTGATACAATGATTACAGATGCTTTCCTCAAAGCAGATGACTACATAGAGATTACA GGTGCTGGAGGAAAAAAGTATCGCATTTCTACAGCAATTGACGACATGGAAGCCTATACT AAGCTGACAGATAACATTTTTCTGGAGATTTTATACTCTACTGATCCCAAATTGAAAGAC GCACGAGAGATTTTAAAACAAATTGAATACCGTAATCTATTCAAGTATGTGGGTGAGACG CAGCCAACAGGACAAATAAAGATTAAAAGGGAGGACTATGAATCTCTTCCAAAAGAGGTT GCCAGTGCTAAACCCAAAGTATTGCTAGACGTGAAACTGAAGGCTGAAGATTTTATAGTG GATGTTATCAACATGGATTATGGAATGCAAGAAAAGAATCCAATTGATCATGTTAGCTTC TATTGTAAGACTGCCCCCAACAGAGCAATCAGGATTACTAAAAACCAGGTTTCACAACTT CTGCCAGAGAAATTTGCAGAGCAGCTGATTCGAGTATATTGTAAGAAGGTGGACAGAAAG AGTTTGTATGCCGCAAGACAATATTTTGTTCAGTGGTGTGCAGACAGAAATTTCACCAAG CCGCAGGATGGCGATGTTATAGCCCCACTCATAACACCTCAAAAAAAGGAATGGAACGAC AGTACTTCAGTCCAAAATCCAACTCGCCTCCGAGAAGCATCCAAAAGCAGAGTCCAGCTT TTTAAAGATGACCCAATGTGA Clone variation with respect to NM_015474.3 >OriGene 5' read for NM_015474 unedited
GGGTGGTCAGCATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGGGGCCC TGCTGTCAGTGCGCCTGCGCGCGGGTCCGGCGCCGAGGTTCTTGACTGCTGTGCCGGACG CCAGGTGTAGCCATGCAGCGAGCCGATTCCGAGCAGCCCTCCAAGCGTCCCCGTTGCGAT GACAGCCCGAGAACCCCCTCAAACACCCCTTCCGCAGAGGCAGACTGGTCCCCGGGCCTG GAACTCCATCCCGACTACAAGACATGGGGTCCGGAGCAGGTGTGCTCCTTCCTCAGGCGC GGTGGCTTTGAAGAGCCGGTGCTGCTGAAGAACATCCGAGAAAATGAAATCACAGGCGCA TTACTGCCTTGTCTTGATGAGTCTCGTTTTGAAAATCTTGGAGTAAGTTCCTTGGGGGAG AGGAAGAAGCTGCTTAGTTATATCCAGCGATTGGTTCAAATCCACGTTGATACAATGAAG GTAATTAATGATCCTATCCATGGCCACATTGAGCTCCACCCTCTCCTCGTCCGAATCATT GATACACCTCAATTTCAACGTCTTCGATACATCAAACAGCTGGGAGGTGGTTACTATGTT TTTCCAGGAGCTTCACACAATCGATTTGAGCATAGTCTAGGGGTGGGGTATCTAGCAGGA TGTCTAGTTCACGCACTGGGTGAAAAACAACCAGAGCTGCAGATAAGTGAACGAGATGTT CTCTGTGTTCAGATTGCTGGACTTTGTCATGATCTCGGTCATGGGCCATTTTCTCACATG TTTGATGGACGATTTATTCCACTTGCTCGCCCGGNAGGTGAAATGGACGCATGAACAAGG CTCAGTTATGATGTTTGAGCACCTTATTAATTCTATGGGATNAGCCTGTCATGGACN >OriGene 3' read for NM_015474 unedited
NANGATCGAGTTTTTTTTTTTTTTTTTTGAAGGAGAAAGCTTTAATAATATTAAAAATAG CAAGGTAATGCTTTTCATAGTATAGTAAGATTTGCCTAATACCATCTTATTTCTTTGATT AAAAGTTACTTAGCTTCAGCATGCGTGTACATTTAAAATACAAAATTAAAGCATGAGTTG TCATTAATTTGCAGAATTCTATGATTGAAGCCTCTAAATGAATTGTGCAGGAGAGGGAGT TTGTAAACAACTGACTACAGACATTCACATTGGGTCATCTTTAAAAAGCTGGACTCTGCT TTTGGATGCTTCTCGGAGGCGAGTTGGATTTTGGACTGAAGTACTGTCGTTCCATTCCTT TTTTTGAGGTGTTATGAGTGGGGCTATAACATCGCCATCCTGCGGCTTGGTGAAATTTCT GTCTGCCCACCACTGAACAAAATATTGTCTTGCGGCATACAAACTCTTTCTGTCCACCTT CTTACAATATACTCGAATCAACTGCTCTGCAAATTTTTCTGGCAGAAATTGTGAAACCCG GGTTTTAATAAATCCTGATTGCTCTGTTGGGGGCAATCTTACCATAGAAGCTAACATGGT CAAATGGATTCTTTTCTTGGTTTCCTAAATCCTGGTGGGAAACTCCACTATAAAATCTTC AGCCTTCAGGTTTAACTTTTAGCAATACTTTGGGTTTAACCCTGGGCACCCTTTTTTGGG AAAAAATAATAAGCGCCCCCTTTTAAAACCTTATTTGGCCGGGGGGGGGGGGGGTAAACC CAATACTTGGATAAATTACCGGGTTCCAAATTTGGTTTAAAAAACCTCCCGGTGCGGCTT TCTAATATGGGGTCCACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_015474 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015474.2, NP_056289.2 |
| RefSeq Size | 2701 bp |
| RefSeq ORF | 1881 bp |
| Locus ID | 25939 |
| UniProt ID | Q9Y3Z3 |
| Domains | SAM, HD |
| Gene Summary | This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010] |
Citations (7)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation
,null,
Cell & Bioscience
,PubMed ID 34238351
[SAMHD1]
|
|
PIAS1 Potentiates the Anti-viral Activity of SAMHD1 through SUMOylation
,Saiada, F;Zhang, K;Li, R;,
Research Square
[SAMHD1]
|
|
Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication
,null,
Cell reports
,PubMed ID 31291580
[SAMHD1]
|
|
Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication
,Zhang, K;Lv, D;Li, R;,
bioRxiv
[SAMHD1]
|
|
DNA damage response signaling does not trigger redistribution of SAMHD1 to nuclear foci
,Medeiros, AC;Soares, CS;Coelho, PO;Vieira, NA;Baqui, MMA;Teixeira, FR;Gomes, MD;,
Biochem. Biophys. Res. Commun.
,PubMed ID 29614270
[SAMHD1]
|
|
Characterization of the interactions between SIVrcm Vpx and red-capped mangabey SAMHD1
,Li, J;Xu, F;Hu, S;Zhou, J;Mei, S;Zhao, X;Cen, S;Jin, Q;Liang, C;Guo, F;,
Biochem. J.
,PubMed ID 25791246
[SAMHD1]
|
|
SAM domain-containing N-terminal region of SAMHD1 plays a crucial role in its stabilization and restriction of HIV-1 infection
,Shigematsu, S;Hayashi, H;,
Acta medica Nagasakiensia 103-111 58 . March 2014
[SAMHD1]
|
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Resources
Other Versions
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|---|---|---|---|
| RC206013 | SAMHD1 (Myc-DDK-tagged)-Human SAM domain and HD domain 1 (SAMHD1) |
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| RC206013L1 | Lenti ORF clone of Human SAM domain and HD domain 1 (SAMHD1), Myc-DDK-tagged |
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| RC206013L2 | Lenti ORF clone of Human SAM domain and HD domain 1 (SAMHD1), mGFP tagged |
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| RC206013L3 | Lenti ORF clone of Human SAM domain and HD domain 1 (SAMHD1), Myc-DDK-tagged |
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| RC206013L4 | Lenti ORF clone of Human SAM domain and HD domain 1 (SAMHD1), mGFP tagged |
CNY 7,064.00 |
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| RG206013 | SAMHD1 (tGFP-tagged) - Human SAM domain and HD domain 1 (SAMHD1) |
CNY 6,264.00 |
