TTLL4 (NM_014640) Human Untagged Clone

CAT#: SC114928

TTLL4 (untagged)-Human tubulin tyrosine ligase-like family, member 4 (TTLL4)



  "NM_014640" in other vectors (6)

CNY 12,528.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Goat Polyclonal Anti-TTLL4 Antibody
    • 100 ug

CNY 5,371.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC114928 sequence for NM_014640 edited (data generated by NextGen Sequencing)
ATGGCCTCAGCAGGAACACAGCACTATAGTATTGGCCTCCGCCAGAAAAACAGCTTCAAG
CAGAGTGGTCCCTCAGGCACAGTACCTGCCACGCCACCTGAGAAACCCTCGGAGGGCAGA
GTCTGGCCTCAGGCCCATCAGCAAGTGAAGCCAATCTGGAAGCTGGAAAAGAAGCAAGTG
GAGACACTGTCAGCAGGGTTGGGCCCAGGCCTCTTGGGCGTCCCACCCCAGCCAGCATAT
TTCTTTTGCCCCAGCACTTTATGTAGCTCTGGGACCACGGCTGTCATTGCAGGCCACAGC
AGTTCCTGTTACCTACACTCTCTCCCGGACTTGTTCAACAGCACCCTGCTATACCGCCGC
TCCAGCTATAGGCAAAAACCGTACCAGCAACTGGAGTCTTTCTGCTTGCGTTCGAGCCCG
TCAGAAAAAAGCCCTTTTTCTCTCCCTCAAAAGAGCCTCCCTGTCAGTCTCACTGCCAAC
AAGGCCACTTCTTCCATGGTCTTCTCCATGGCCCAGCCCATGGCCTCCTCATCCACAGAA
CCATACCTCTGCTTGGCAGCGGCTGGGGAAAACCCTTCAGGGAAGAGCCTGGCCTCTGCC
ATCTCAGGGAAGATCCCATCTCCACTCTCTTCCTCCTATAAGCCCATGCTGAATAATAAT
TCCTTCATGTGGCCAAATAGCACGCCAGTGCCTTTATTGCAGACCACACAGGGCCTGAAG
CCAGTATCGCCACCCAAGATCCAGCCTGTCTCCTGGCATCATTCAGGGGGTACTGGAGAC
TGTGCACCGCAGCCTGTTGACCATAAGGTGCCCAAAAGCATTGGCACTGTCCCAGCTGAT
GCCAGTGCCCATATCGCCTTGTCTACCGCTAGCTCCCACGACACATCCACCACCAGTGTT
GCCTCTTCCTGGTATAACCGGAATAACTTAGCCATGAGGGCAGAGCCACTTTCCTGTGCT
CTGGATGACAGCTCTGATTCCCAGGATCCAACTAAGGAGATTCGGTTCACTGAGGCCGTG
AGGAAATTGACCGCAAGAGGCTTTGAGAAGATGCCGAGGCAAGGCTGCCAGCTTGAACAG
TCTAGTTTCCTGAACCCCAGCTTCCAGTGGAATGTCCTCAACAGGAGCAGGCGGTGGAAA
CCTCCTGCGGTAAATCAGCAGTTTCCTCAGGAGGATGCTGGATCGGTCAGGCGGGTCCTC
CCTGGTGCCTCAGATACCTTGGGGTTGGACAATACAGTCTTCTGTACCAAGCGTATCAGC
ATTCACCTCCTTGCCTCACATGCCAGTGGGCTCAATCACAACCCTGCCTGTGAATCTGTA
ATTGACTCCTCAGCATTTGGAGAAGGCAAAGCTCCAGGTCCCCCTTTTCCTCAAACTCTT
GGCATAGCCAACGTGGCCACCCGCCTCTCTTCCATCCAGCTGGGCCAGTCTGAGAAGGAG
AGACCTGAGGAGGCCAGGGAGCTGGACTCATCTGATAGGGATATTAGTTCAGCTACTGAC
CTCCAGCCAGATCAGGCTGAGACTGAAGATACAGAAGAAGAACTAGTAGATGGTTTGGAA
GACTGTTGTAGCCGTGATGAGAATGAAGAGGAGGAGGGAGACTCAGAGTGCTCCTCATTA
AGTGCTGTCTCCCCCAGCGAATCGGTGGCCATGATCTCTAGAAGCTGTATGGAAATTCTG
ACCAAACCCCTTTCCAATCATGAGAAAGTTGTCCGACCAGCCCTCATCTACAGTCTCTTT
CCCAACGTTCCCCCTACCATCTATTTTGGCACTCGGGATGAGAGAGTGGAGAAACTTCCC
TGGGAACAGAGGAAGTTGCTCCGATGGAAGATGAGCACAGTGACCCCCAACATTGTCAAG
CAGACCATTGGACGGTCCCACTTCAAAATCAGCAAAAGAAACGATGACTGGCTGGGCTGC
TGGGGTCACCACATGAAGTCTCCTAGTTTCCGATCCATTCGAGAGCATCAGAAGCTAAAC
CATTTCCCAGGCTCATTCCAGATTGGGAGGAAGGACCGGCTATGGCGGAACCTGTCACGT
ATGCAGAGCCGCTTTGGCAAGAAGGAGTTCAGTTTCTTCCCCCAGTCCTTTATCCTGCCC
CAGGACGCCAAGCTCCTGCGCAAAGCGTGGGAGAGCAGCAGCCGCCAAAAGTGGATTGTG
AAGCCACCAGCATCAGCTCGAGGCATTGGCATCCAGGTTATTCACAAGTGGAGTCAGCTC
CCCAAGCGAAGGCCCCTCCTGGTACAGAGGTATCTACACAAACCCTACCTCATCAGCGGC
AGCAAGTTTGACCTGCGGATCTATGTTTATGTCACTTCCTACGATCCTCTGCGGATTTAC
CTCTTTTCAGATGGACTGGTCCGCTTTGCCAGTTGCAAGTATTCGCCTTCCATGAAGAGC
CTTGGCAATAAGTTCATGCACCTGACCAACTACAGTGTCAATAAAAAGAATGCCGAGTAC
CAGGCCAATGCAGATGAAATGGCTTGCCAGGGCCACAAATGGGCACTGAAGGCTTTGTGG
AACTACCTGAGCCAGAAGGGAGTCAATAGCGACGCCATCTGGGAGAAGATAAAGGATGTT
GTTGTCAAAACTATCATCTCGTCAGAGCCCTATGTGACCAGCCTGCTCAAGATGTATGTG
CGACGGCCCTATAGCTGCCATGAACTCTTTGGTTTTGACATCATGCTAGACGAAAACCTC
AAGCCCTGGGTCCTGGAAGTCAACATTTCCCCAAGCCTCCACTCCAGCTCTCCACTGGAT
ATCAGCATCAAAGGCCAGATGATTCGTGACCTTCTGAATCTGGCAGGTTTTGTCCTGCCC
AATGCAGAGGATATCATTTCCAGCCCCAGCAGCTGCAGCAGCTCCACCACCAGCCTGCCC
ACCTCCCCTGGGGACAAATGTCGAATGGCTCCAGAGCATGTCACTGCACAGAAGATGAAG
AAAGCCTATTATCTGACCCAGAAAATTCCTGATCAGGACTTCTATGCATCTGTGCTGGAT
GTCCTGACACCAGATGATGTTCGGATTCTGGTTGAGATGGAAGATGAGTTTTCTCGCCGT
GGTCAGTTTGAACGAATTTTTCCTTCTCATATCTCCTCTCGCTATCTCCGCTTTTTTGAG
CAGCCACGATATTTCAACATTCTCACCACCCAATGGGAACAGAAATACCATGGCAACAAG
CTTAAAGGAGTAGATCTGCTCCGGAGTTGGTGCTACAAAGGGTTCCACATGGGAGTTGTC
TCTGATTCTGCTCCAGTGTGGTCTCTCCCGACATCACTTCTGACTATCTCAAAGGATGAC
GTGATACTCAATGCCTTCAGCAAATCAGAGACTAGCAAGCTGGGAAAACAAAGCTCCTGT
GAGGTTAGCCTACTACTCTCTGAAGACGGGACCACGCCCAAATCCAAGAAGACTCAAGCT
GGCCTTTCCCCTTATCCCCAGAAACCCAGTTCCTCAAAGGACAGTGAGGACACCAGCAAA
GAGCCCAGCCTTTCTACCCAGACGTTACCTGTGATCAAGTGCTCTGGGCAGACTTCAAGA
CTTTCTGCTTCCTCCACTTTCCAGTCAATCAGTGACTCCCTCCTGGCTGTGAGCCCATAA

Clone variation with respect to NM_014640.4
>OriGene 5' read for NM_014640 unedited
AGTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACCAGGCCGGGTAGC
CCAGCAGGCCGAGGGAGGAAGTAGCGTGGAGCCGGTGCCGAGCCGGGGCGAAGCTGGATC
CCCTAGACTGACAGACTTCAAGGATGCAGCTGCTACTACCGGAGGTGTGTGGCACCTTAC
CTCAGCAAGGCCATGAGACCGTGTGGCCATGATGTGGGCCCCTCATGGCCTCAGCAGGAA
CACAGCACTATAGTATTGGCCTCCGCCAGAAAAACAGCTTCAAGCAGAGTGGTCCCTCAG
GCACAGTACCTGCCACGCCACCTGAGAAACCCTCGGAGGGCAGAGTCTGGCCTCAGGCCC
ATCAGCAAGTGAAGCCAATCTGGAAGCTGGAAAAGAAGCAAGTGGAGACACTGTCAGCAG
GGTTGGGCCCAGGCCTCTTGGGCGTCCCACCCCAGCCAGCATATTTCTTTTGCCCCAGCA
CTTTATGTAGCTCTGGGACCACGGCTGTCATTGCAGGCCACAGCAGTTCCTGTTACCTAC
ACTCTCTCCCGGACTTGTTCAACAGCACCCTGCTATACCGCCGCTCCAGCTATAGGCAAA
AACCGTACCAGCAACTGGAGTCTTTCTGCTTGCGTTCGAGCCCGTCAGAAAAAAGCCCTT
TTTCTCTCCCTCAAAAGAGCCTCCCTGTCAGTCTCACTGCCAACAAGGCCACTTCTTCCA
TGGTCTTCTCCATGGCCCAGCCCATGGNCTNCTCATCCACAGAACCATACCTCTGCTTGG
CAGCGGCTGGNGAAAACCTTCAGGNAAGAGCTGGCCTCTGCCTCTCAGGNAAGACCCATC
TCACTCTCTTTCTCTANAAGCCATGCTGAATATAATCCTTCAGTGGCCAATACACGCCAG
GCCTTTATGCAGACACCAGGCCTGAGCCAGTATCGCACCAGACCAN
>OriGene 3' read for NM_014640 unedited
NCCTTCTAGTCCGGGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTAAGGTAGAA
AACCAAAACCTGCTTTATAAGGCTGCGTGGCCACCACTGGCTTCTCTGCTGAGATATGAG
GTGCCAGCCAGGCAGACAGGTGACAGAGGGTGACCCTTCCTCACCTTCTCCCCATCACTA
CCATCCCTCCGGGCCTACAAATACCCATCTCTATAATGCAACCACTTCAAAAAATACTCT
GACGAGGGACAGGGGGAAAGGGGCAGGGGGTCATACTGGCCTGAACAGCACGCTGGTTCC
CGCGAGGTACCTGATGCCCATGCTCCTGGGCAGAGGCCTCTTGGAGAGAGGCCACTTATG
GGCTCACAGCCAGGAGGGAGCCACTGATCGACTGGAACGCCGGGGATCCATACTGCTTCC
CCGTCTGCCCAGCCCCCTTGCTCCCCCTTAACCCCCCGCGCATCACACGCTCGCTTCTTC
TCTAGTCTCCCTACCGCCTTTAACCCAACTTCCCTTACCCTCCCCCCCAGTCTTATACTC
TCCTACCCCTCCACCCGCCCCTACTCCCCCCACCCTTCCCCACCCTCCTACTCACCTAAC
CCACTCTCACCCCCGCGCCGCCCACGCGACTTCCACCCTCACTGCGCCACCGCCACAACA
CCTTATCCCCCCACATTCCCCACCGCCGTCCTCATTCTATCCCACTACCATACTGGGCCC
CGACTCTCCATCACTTCTTCTGACCTCACCTTGCCCTTTGCTTGCCCCGCCCCATTATCT
TCCCCCCCTCTACAGCCATCTCACAAATTTTTCTATACTCCCTCGCGCTACTCTATCAAT
CCCCTACTTTACCTGTTACCCACGTTACCCCCCCGCTTCTTCCTTACATTATCCTCGCCA
TCCCAACCATTCCCCCTATCTCCCCCACACCACCACCGTCCAGCATACCTCAACACCCTC
TAC
Restriction Sites NotI-NotI     
ACCN NM_014640
Insert Size 1700 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_014640.2, NP_055455.2
RefSeq Size 4208 bp
RefSeq ORF 3600 bp
Locus ID 9654
UniProt ID Q14679
Domains TTL
Gene Summary Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4. Also acts as a monoglutamylase: generates monoglutamylation of CGAS, leading to impair the nucleotidyltransferase activity of CGAS.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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