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TTLL4 (NM_014640) Human Untagged Clone
CAT＃: SC114928
TTLL4 (untagged)-Human tubulin tyrosine ligase-like family, member 4 (TTLL4)
CNY 12,528.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114928 sequence for NM_014640 edited (data generated by NextGen Sequencing)
ATGGCCTCAGCAGGAACACAGCACTATAGTATTGGCCTCCGCCAGAAAAACAGCTTCAAG CAGAGTGGTCCCTCAGGCACAGTACCTGCCACGCCACCTGAGAAACCCTCGGAGGGCAGA GTCTGGCCTCAGGCCCATCAGCAAGTGAAGCCAATCTGGAAGCTGGAAAAGAAGCAAGTG GAGACACTGTCAGCAGGGTTGGGCCCAGGCCTCTTGGGCGTCCCACCCCAGCCAGCATAT TTCTTTTGCCCCAGCACTTTATGTAGCTCTGGGACCACGGCTGTCATTGCAGGCCACAGC AGTTCCTGTTACCTACACTCTCTCCCGGACTTGTTCAACAGCACCCTGCTATACCGCCGC TCCAGCTATAGGCAAAAACCGTACCAGCAACTGGAGTCTTTCTGCTTGCGTTCGAGCCCG TCAGAAAAAAGCCCTTTTTCTCTCCCTCAAAAGAGCCTCCCTGTCAGTCTCACTGCCAAC AAGGCCACTTCTTCCATGGTCTTCTCCATGGCCCAGCCCATGGCCTCCTCATCCACAGAA CCATACCTCTGCTTGGCAGCGGCTGGGGAAAACCCTTCAGGGAAGAGCCTGGCCTCTGCC ATCTCAGGGAAGATCCCATCTCCACTCTCTTCCTCCTATAAGCCCATGCTGAATAATAAT TCCTTCATGTGGCCAAATAGCACGCCAGTGCCTTTATTGCAGACCACACAGGGCCTGAAG CCAGTATCGCCACCCAAGATCCAGCCTGTCTCCTGGCATCATTCAGGGGGTACTGGAGAC TGTGCACCGCAGCCTGTTGACCATAAGGTGCCCAAAAGCATTGGCACTGTCCCAGCTGAT GCCAGTGCCCATATCGCCTTGTCTACCGCTAGCTCCCACGACACATCCACCACCAGTGTT GCCTCTTCCTGGTATAACCGGAATAACTTAGCCATGAGGGCAGAGCCACTTTCCTGTGCT CTGGATGACAGCTCTGATTCCCAGGATCCAACTAAGGAGATTCGGTTCACTGAGGCCGTG AGGAAATTGACCGCAAGAGGCTTTGAGAAGATGCCGAGGCAAGGCTGCCAGCTTGAACAG TCTAGTTTCCTGAACCCCAGCTTCCAGTGGAATGTCCTCAACAGGAGCAGGCGGTGGAAA CCTCCTGCGGTAAATCAGCAGTTTCCTCAGGAGGATGCTGGATCGGTCAGGCGGGTCCTC CCTGGTGCCTCAGATACCTTGGGGTTGGACAATACAGTCTTCTGTACCAAGCGTATCAGC ATTCACCTCCTTGCCTCACATGCCAGTGGGCTCAATCACAACCCTGCCTGTGAATCTGTA ATTGACTCCTCAGCATTTGGAGAAGGCAAAGCTCCAGGTCCCCCTTTTCCTCAAACTCTT GGCATAGCCAACGTGGCCACCCGCCTCTCTTCCATCCAGCTGGGCCAGTCTGAGAAGGAG AGACCTGAGGAGGCCAGGGAGCTGGACTCATCTGATAGGGATATTAGTTCAGCTACTGAC CTCCAGCCAGATCAGGCTGAGACTGAAGATACAGAAGAAGAACTAGTAGATGGTTTGGAA GACTGTTGTAGCCGTGATGAGAATGAAGAGGAGGAGGGAGACTCAGAGTGCTCCTCATTA AGTGCTGTCTCCCCCAGCGAATCGGTGGCCATGATCTCTAGAAGCTGTATGGAAATTCTG ACCAAACCCCTTTCCAATCATGAGAAAGTTGTCCGACCAGCCCTCATCTACAGTCTCTTT CCCAACGTTCCCCCTACCATCTATTTTGGCACTCGGGATGAGAGAGTGGAGAAACTTCCC TGGGAACAGAGGAAGTTGCTCCGATGGAAGATGAGCACAGTGACCCCCAACATTGTCAAG CAGACCATTGGACGGTCCCACTTCAAAATCAGCAAAAGAAACGATGACTGGCTGGGCTGC TGGGGTCACCACATGAAGTCTCCTAGTTTCCGATCCATTCGAGAGCATCAGAAGCTAAAC CATTTCCCAGGCTCATTCCAGATTGGGAGGAAGGACCGGCTATGGCGGAACCTGTCACGT ATGCAGAGCCGCTTTGGCAAGAAGGAGTTCAGTTTCTTCCCCCAGTCCTTTATCCTGCCC CAGGACGCCAAGCTCCTGCGCAAAGCGTGGGAGAGCAGCAGCCGCCAAAAGTGGATTGTG AAGCCACCAGCATCAGCTCGAGGCATTGGCATCCAGGTTATTCACAAGTGGAGTCAGCTC CCCAAGCGAAGGCCCCTCCTGGTACAGAGGTATCTACACAAACCCTACCTCATCAGCGGC AGCAAGTTTGACCTGCGGATCTATGTTTATGTCACTTCCTACGATCCTCTGCGGATTTAC CTCTTTTCAGATGGACTGGTCCGCTTTGCCAGTTGCAAGTATTCGCCTTCCATGAAGAGC CTTGGCAATAAGTTCATGCACCTGACCAACTACAGTGTCAATAAAAAGAATGCCGAGTAC CAGGCCAATGCAGATGAAATGGCTTGCCAGGGCCACAAATGGGCACTGAAGGCTTTGTGG AACTACCTGAGCCAGAAGGGAGTCAATAGCGACGCCATCTGGGAGAAGATAAAGGATGTT GTTGTCAAAACTATCATCTCGTCAGAGCCCTATGTGACCAGCCTGCTCAAGATGTATGTG CGACGGCCCTATAGCTGCCATGAACTCTTTGGTTTTGACATCATGCTAGACGAAAACCTC AAGCCCTGGGTCCTGGAAGTCAACATTTCCCCAAGCCTCCACTCCAGCTCTCCACTGGAT ATCAGCATCAAAGGCCAGATGATTCGTGACCTTCTGAATCTGGCAGGTTTTGTCCTGCCC AATGCAGAGGATATCATTTCCAGCCCCAGCAGCTGCAGCAGCTCCACCACCAGCCTGCCC ACCTCCCCTGGGGACAAATGTCGAATGGCTCCAGAGCATGTCACTGCACAGAAGATGAAG AAAGCCTATTATCTGACCCAGAAAATTCCTGATCAGGACTTCTATGCATCTGTGCTGGAT GTCCTGACACCAGATGATGTTCGGATTCTGGTTGAGATGGAAGATGAGTTTTCTCGCCGT GGTCAGTTTGAACGAATTTTTCCTTCTCATATCTCCTCTCGCTATCTCCGCTTTTTTGAG CAGCCACGATATTTCAACATTCTCACCACCCAATGGGAACAGAAATACCATGGCAACAAG CTTAAAGGAGTAGATCTGCTCCGGAGTTGGTGCTACAAAGGGTTCCACATGGGAGTTGTC TCTGATTCTGCTCCAGTGTGGTCTCTCCCGACATCACTTCTGACTATCTCAAAGGATGAC GTGATACTCAATGCCTTCAGCAAATCAGAGACTAGCAAGCTGGGAAAACAAAGCTCCTGT GAGGTTAGCCTACTACTCTCTGAAGACGGGACCACGCCCAAATCCAAGAAGACTCAAGCT GGCCTTTCCCCTTATCCCCAGAAACCCAGTTCCTCAAAGGACAGTGAGGACACCAGCAAA GAGCCCAGCCTTTCTACCCAGACGTTACCTGTGATCAAGTGCTCTGGGCAGACTTCAAGA CTTTCTGCTTCCTCCACTTTCCAGTCAATCAGTGACTCCCTCCTGGCTGTGAGCCCATAA Clone variation with respect to NM_014640.4 >OriGene 5' read for NM_014640 unedited
AGTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACCAGGCCGGGTAGC CCAGCAGGCCGAGGGAGGAAGTAGCGTGGAGCCGGTGCCGAGCCGGGGCGAAGCTGGATC CCCTAGACTGACAGACTTCAAGGATGCAGCTGCTACTACCGGAGGTGTGTGGCACCTTAC CTCAGCAAGGCCATGAGACCGTGTGGCCATGATGTGGGCCCCTCATGGCCTCAGCAGGAA CACAGCACTATAGTATTGGCCTCCGCCAGAAAAACAGCTTCAAGCAGAGTGGTCCCTCAG GCACAGTACCTGCCACGCCACCTGAGAAACCCTCGGAGGGCAGAGTCTGGCCTCAGGCCC ATCAGCAAGTGAAGCCAATCTGGAAGCTGGAAAAGAAGCAAGTGGAGACACTGTCAGCAG GGTTGGGCCCAGGCCTCTTGGGCGTCCCACCCCAGCCAGCATATTTCTTTTGCCCCAGCA CTTTATGTAGCTCTGGGACCACGGCTGTCATTGCAGGCCACAGCAGTTCCTGTTACCTAC ACTCTCTCCCGGACTTGTTCAACAGCACCCTGCTATACCGCCGCTCCAGCTATAGGCAAA AACCGTACCAGCAACTGGAGTCTTTCTGCTTGCGTTCGAGCCCGTCAGAAAAAAGCCCTT TTTCTCTCCCTCAAAAGAGCCTCCCTGTCAGTCTCACTGCCAACAAGGCCACTTCTTCCA TGGTCTTCTCCATGGCCCAGCCCATGGNCTNCTCATCCACAGAACCATACCTCTGCTTGG CAGCGGCTGGNGAAAACCTTCAGGNAAGAGCTGGCCTCTGCCTCTCAGGNAAGACCCATC TCACTCTCTTTCTCTANAAGCCATGCTGAATATAATCCTTCAGTGGCCAATACACGCCAG GCCTTTATGCAGACACCAGGCCTGAGCCAGTATCGCACCAGACCAN >OriGene 3' read for NM_014640 unedited
NCCTTCTAGTCCGGGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTAAGGTAGAA AACCAAAACCTGCTTTATAAGGCTGCGTGGCCACCACTGGCTTCTCTGCTGAGATATGAG GTGCCAGCCAGGCAGACAGGTGACAGAGGGTGACCCTTCCTCACCTTCTCCCCATCACTA CCATCCCTCCGGGCCTACAAATACCCATCTCTATAATGCAACCACTTCAAAAAATACTCT GACGAGGGACAGGGGGAAAGGGGCAGGGGGTCATACTGGCCTGAACAGCACGCTGGTTCC CGCGAGGTACCTGATGCCCATGCTCCTGGGCAGAGGCCTCTTGGAGAGAGGCCACTTATG GGCTCACAGCCAGGAGGGAGCCACTGATCGACTGGAACGCCGGGGATCCATACTGCTTCC CCGTCTGCCCAGCCCCCTTGCTCCCCCTTAACCCCCCGCGCATCACACGCTCGCTTCTTC TCTAGTCTCCCTACCGCCTTTAACCCAACTTCCCTTACCCTCCCCCCCAGTCTTATACTC TCCTACCCCTCCACCCGCCCCTACTCCCCCCACCCTTCCCCACCCTCCTACTCACCTAAC CCACTCTCACCCCCGCGCCGCCCACGCGACTTCCACCCTCACTGCGCCACCGCCACAACA CCTTATCCCCCCACATTCCCCACCGCCGTCCTCATTCTATCCCACTACCATACTGGGCCC CGACTCTCCATCACTTCTTCTGACCTCACCTTGCCCTTTGCTTGCCCCGCCCCATTATCT TCCCCCCCTCTACAGCCATCTCACAAATTTTTCTATACTCCCTCGCGCTACTCTATCAAT CCCCTACTTTACCTGTTACCCACGTTACCCCCCCGCTTCTTCCTTACATTATCCTCGCCA TCCCAACCATTCCCCCTATCTCCCCCACACCACCACCGTCCAGCATACCTCAACACCCTC TAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014640 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014640.2, NP_055455.2 |
| RefSeq Size | 4208 bp |
| RefSeq ORF | 3600 bp |
| Locus ID | 9654 |
| UniProt ID | Q14679 |
| Domains | TTL |
| Gene Summary | Glutamylase which preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4. Also acts as a monoglutamylase: generates monoglutamylation of CGAS, leading to impair the nucleotidyltransferase activity of CGAS.[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205206 | TTLL4 (Myc-DDK-tagged)-Human tubulin tyrosine ligase-like family, member 4 (TTLL4) |
CNY 12,520.00 |
|
| RC205206L1 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 4 (TTLL4), Myc-DDK-tagged |
CNY 14,920.00 |
|
| RC205206L2 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 4 (TTLL4), mGFP tagged |
CNY 12,160.00 |
|
| RC205206L3 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 4 (TTLL4), Myc-DDK-tagged |
CNY 12,160.00 |
|
| RC205206L4 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 4 (TTLL4), mGFP tagged |
CNY 12,160.00 |
|
| RG205206 | TTLL4 (tGFP-tagged) - Human tubulin tyrosine ligase-like family, member 4 (TTLL4) |
CNY 14,120.00 |
