United States
Germany
Japan
United Kingdom
China
SERPING1 (NM_000062) Human Untagged Clone
CAT＃: SC115553
SERPING1 (untagged)-Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1
CNY 3,728.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C1IN; C1INH; C1NH; HAE1; HAE2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000062, the custom clone sequence may differ by one or more nucleotides
ATGGCCTCCAGGCTGACCCTGCTGACCCTCCTGCTGCTGCTGCTGGCTGGGGATAGAGCCTCCTCAAATC CAAATGCTACCAGCTCCAGCTCCCAGGATCCAGAGAGTTTGCAAGACAGAGGCGAAGGGAAGGTCGCAAC AACAGTTATCTCCAAGATGCTATTCGTTGAACCCATCCTGGAGGTTTCCAGCTTGCCGACAACCAACTCA ACAACCAATTCAGCCACCAAAATAACAGCTAATACCACTGATGAACCCACCACACAACCCACCACAGAGC CCACCACCCAACCCACCATCCAACCCACCCAACCAACTACCCAGCTCCCAACAGATTCTCCTACCCAGCC CACTACTGGGTCCTTCTGCCCAGGACCTGTTACTCTCTGCTCTGACTTGGAGAGTCATTCAACAGAGGCC GTGTTGGGGGATGCTTTGGTAGATTTCTCCCTGAAGCTCTACCACGCCTTCTCAGCAATGAAGAAGGTGG AGACCAACATGGCCTTTTCCCCATTCAGCATCGCCAGCCTCCTTACCCAGGTCCTGCTCGGGGCTGGGGA GAACACCAAAACAAACCTGGAGAGCATCCTCTCTTACCCCAAGGACTTCACCTGTGTCCACCAGGCCCTG AAGGGCTTCACGACCAAAGGTGTCACCTCAGTCTCTCAGATCTTCCACAGCCCAGACCTGGCCATAAGGG ACACCTTTGTGAATGCCTCTCGGACCCTGTACAGCAGCAGCCCCAGAGTCCTAAGCAACAACAGTGACGC CAACTTGGAGCTCATCAACACCTGGGTGGCCAAGAACACCAACAACAAGATCAGCCGGCTGCTAGACAGT CTGCCCTCCGATACCCGCCTTGTCCTCCTCAATGCTATCTACCTGAGTGCCAAGTGGAAGACAACATTTG ATCCCAAGAAAACCAGAATGGAACCCTTTCACTTCAAAAACTCAGTTATAAAAGTGCCCATGATGAATAG CAAGAAGTACCCTGTGGCCCATTTCATTGACCAAACTTTGAAAGCCAAGGTGGGGCAGCTGCAGCTCTCC CACAATCTGAGTTTGGTGATCCTGGTACCCCAGAACCTGAAACATCGTCTTGAAGACATGGAACAGGCTC TCAGCCCTTCTGTTTTCAAGGCCATCATGGAGAAACTGGAGATGTCCAAGTTCCAGCCCACTCTCCTAAC ACTACCCCGCATCAAAGTGACGACCAGCCAGGATATGCTCTCAATCATGGAGAAATTGGAATTCTTCGAT TTTTCTTATGACCTTAACCTGTGTGGGCTGACAGAGGACCCAGATCTTCAGGTTTCTGCGATGCAGCACC AGACAGTGCTGGAACTGACAGAGACTGGGGTGGAGGCGGCTGCAGCCTCCGCCATCTCTGTGGCCCGCAC CCTGCTGGTCTTTGAAGTGCAGCAGCCCTTCCTCTTCGTGCTCTGGGACCAGCAGCACAAGTTCCCTGTC TTCATGGGGCGAGTATATGACCCCAGGGCCTGA >OriGene 5' read for NM_000062 unedited
TTCAGATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGGAGTCCGCTG ACGTCGCCGCCCAGATGGCCTCCAGGCTGACCCTGCTGACCCTCCTGCTGCTGCTGCTGG CTGGGGATAGAGCCTCCTCAAATCCAAATGCTACCAGCTCCAGCTCCCAGGATCCAGAGA GTTTGCAAGACAGAGGCGAAGGGAAGGTCGCAACAACAGTTATCTCCAAGATGCTATTCG TTGAACCCATCCTGGAGGTTTCCAGCTTGCCGACAACCAACTCAACAACCAATTCAGCCA CCAAAATAACAGCTAATACCACTGATGAACCCACCACACAACCCACCACAGAGCCCACCA CCCAACCCACCATCCAACCCACCCAACCAACTACCCAGCTCCCAACAGATTCTCCTACCC AGCCCACTACTGGGTCCTTCTGCCCAGGACCTGTTACTCTCTGCTCTGACTTGGAGAGTC ATTCAACAGAGGCCGTGTTGGGGGATGCTTTGGTAGATTTCTCCCTGAAGCTCTACCACG CCTTCTCAGCAATGAAGAAGGTGGAGACCAACATGGCCTTTTCCCCATTCAGCATCGCCA GCCTCCTTACCCAGGTCCTGCTCGGGGCTGGGGAGAACACCAAAACAAACTTGGAGAGCA TCCTCTCTTACCCCAAGGACTTCACCTGTGTCCACCAGGCCCTGAAGGGCTTCACGACCA AAGGTGTCACCTCAGTCTCTCAGATCTTCCACAGCCCAGACCTGGCCATAAGGGACACCT TTGTGAATGCCTCTCGGACCCTGTACAGCAGCAGCCCCAGAGTCCTAAAGCACAACAGTG ACGCCAACTTGGAGCTCATCACACCTGGGTGGCNCNNAGACACCACNNACAGATCAGCCG GCTGCTAGACAGTCTGCCCTTCGATACCGNCTTGTNCTNCTCATGCTATCTACTGAGTGC CAGTGGAAGACACATA >OriGene 3' read for NM_000062 unedited
GACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTCTGTCAGGTTTT ATTTATAGAGTCTGGTGAACTTGAACTAGAGAAAGCTGCAAAAAGTGGTTTGGAGAGCAT GGCAGGGCCATGGAGAAGGGCTAATAGAAGCAGGTCCCTTGCCCAGACCCTCAGGGAGCC CTTTTGGTGGATAGCGGACACCTGAGGCAGGAGGTGGCAGGGGCCAAGTCCAGGCAGGCA GCAGCAGGGCTGCAACTGAGAGCTGAGGCTGGAGAGGTAGCGCTCGCCCTAACCTGATCC TGCAGGTCTCAGGCCCTGGGGTCATATACTCGCCCCATGAAGACAGGGAACTTGTGCTGC TGGTCCCAGAGCACGAAGAGGAAGGGCTGCTGCACTTCAAAGACCAGCAGGGTGCGGGCC ACAGAGATGGCGGAGGCTGCAGCCGCCTCCACCCCAGTCTCTGTCAGTTCCAGCACTGTC TGGTGCTGCATCGCAGAAACCTGAAGATCTGGGTCCTCTGTCAGCCCACCCAGGTTAAGG TCATAAGACCACTCGAAGAATTCCAATCTCTCCATGATTGAGACGATAACCTCGCTTGGT CCTCACTCTGATGCCGGGCAGTGTTAGGATAGTGCGCCTGCACCTTGCACATTTCCACTT TCCCCCTGATCGGCCTCGAAAACGAAGGGCTCAAAGCCCGTCTCCTGCCTCCCACAACAT GCTTTACGTCCCGTGGTACCCGGACTACTAACCCCTATTGCCGCCAACCCCCCTGTCCCC CCTCCCTTCCAAATCCGCCCCACCACGCCCTCCGACCCTCACGTCTTCTTCCCCGCCTCC CACACCCCCCCTTCACCGACGCCTCCCCCCCCCTCCTCCCACATCGCCCACCCCCCTGCA CTCCTCCCCTCCCCCCGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000062 |
| Insert Size | 1820 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000062.2, NP_000053.2 |
| RefSeq Size | 1984 bp |
| RefSeq ORF | 1503 bp |
| Locus ID | 710 |
| UniProt ID | P05155 |
| Domains | SERPIN |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| Gene Summary | This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, May 2020] Transcript Variant: This variant (1) represents the longer transcript. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function
,Søren E. Degn, Lisbeth Jensen, Annette G. Hansen, Duygu Duman, Mustafa Tekin, Jens C. Jensenius, and Steffen Thiel,
J. Immunol., Oct 2012; 189: 3957 - 3969.
[SERPING1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203767 | SERPING1 (Myc-DDK-tagged)-Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1 |
CNY 3,656.00 |
|
| RC203767L1 | Lenti ORF clone of Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203767L2 | Lenti ORF clone of Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC203767L3 | Lenti ORF clone of Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC203767L4 | Lenti ORF clone of Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG203767 | SERPING1 (tGFP-tagged) - Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1 |
CNY 5,256.00 |
其它SERPING1产品
