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RNF139 (NM_007218) Human Untagged Clone
CAT＃: SC115641
RNF139 (untagged)-Human ring finger protein 139 (RNF139)
CNY 4,952.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HRCA1; RCA1; TRC8 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115641 sequence for NM_007218 edited (data generated by NextGen Sequencing)
ATGGCGGCCGTGGGGCCCCCGCAGCAGCAGGTGCGGATGGCCCATCAGCAGGTCTGGGCG GCGCTCGAAGTGGCGCTCCGGGTGCCCTGCCTTTACATCATCGACGCCATCTTCAACTCC TACCCGGATTCCAGCCAAAGCCGGTTCTGCATCGTGCTCCAGATCTTCCTCCGGCTCTTT GGTGTATTTGCATCCAGTATTGTTCTGATCTTGTCACAACGATCACTTTTCAAGTTTTAC ACGTACAGCTCAGCCTTTCTGTTAGCTGCAACTTCAGTGTTGGTGAATTATTATGCTTCT TTGCACATTGACTTCTATGGTGCCTACAACACGTCAGCTTTTGGAATTGAGCTGCTTCCT CGAAAAGGTCCCTCGCTGTGGATGGCACTTATCGTTCTACAGCTAACATTTGGAATTGGA TACGTTACACTACTCCAGATTCATTCCATCTATTCACAATTAATTATTTTGGATCTCTTG GTTCCTGTAATAGGCTTAATCACAGAGCTACCATTACACATCAGAGAGACTTTACTGTTT ACTTCTTCCTTGATTCTCACATTAAATACAGTGTTTGTCCTGGCAGTGAAACTGAAGTGG TTTTATTATTCCACACGATATGTTTATCTTTTGGTGAGGCACATGTATCGAATTTATGGA TTACAGTTATTGATGGAGGACACATGGAAGAGGATTCGTTTCCCAGACATACTACGAGTC TTTTGGCTAACAAGAGTTACAGCTCAGGCTACAGTGTTAATGTACATCTTAAGGATGGCA AATGAAACTGATTCCTTCTTTATTTCTTGGGATGATTTTTGGGACCTCATTTGCAATCTT ATAATTAGTGGGTGCGATTCTACACTAACTGTACTGGGCATGAGTGCTGTAATTTCCTCA GTAGCCCATTATTTGGGGCTTGGAATATTGGCCTTTATTGGATCAACTGAGGAAGATGAC AGGCGTCTTGGCTTTGTTGCACCTGTTTTATTTTTTATTTTGGCTCTTCAGACTGGGTTA AGTGGGCTAAGACCAGAAGAGAGACTTATTCGCTTAAGTAGAAACATGTGCCTTTTATTA ACTGCAGTCCTGCATTTTATCCATGGAATGACAGACCCTGTATTAATGTCTCTCAGTGCC TCTCATGTGTCATCTTTTCGTAGACATTTTCCTGTGCTGTTTGTCTCTGCTTGCCTGTTT ATTCTTCCTGTCTTACTCAGTTATGTTCTTTGGCATCACTATGCACTAAATACATGGTTG TTTGCAGTTACAGCATTTTGTGTGGAACTGTGCTTAAAAGTAATTGTTTCTCTCACTGTT TATACGTTATTCATGATTGATGGCTACTATAATGTCCTCTGGGAAAAGCTTGACGATTAT GTCTACTACGTTCGTTCAACAGGCAGTATTATTGAATTTATATTTGGAGTTGTAATGTTT GGAAATGGGGCTTACACTATGATGTTTGAGTCGGGAAGTAAAATTCGGGCTTTTATGATG TGCCTACATGCATATTTTAACATCTACTTACAAGCCAAAAATGGCTGGAAGACATTTATG AATCGTAGGACTGCTGTGAAGAAAATTAATTCACTTCCTGAAATAAAAGGGAGCCGCTTA CAAGAAATAAATGATGTATGTGCAATCTGCTATCATGAGTTTACAACATCTGCTCGTATT ACACCGTGTAATCATTATTTCCATGCACTTTGCCTTCGGAAATGGCTGTACATTCAAGAT ACTTGTCCAATGTGCCATCAGAAAGTATACATCGAAGATGATATCAAGGATAATTCAAAT GTATCTAACAACAATGGATTTATTCCACCCAATGAAACTCCAGAGGAAGCTGTAAGAGAA GCTGCTGCTGAATCTGACAGGGAATTGAACGAAGATGACAGTACAGATTGTGATGATGAT GTTCAAAGAGAAAGAAATGGAGTGATTCAGCACACAGGCGCAGCAGCTGAAGAATTTAAT GATGATACTGACTGA Clone variation with respect to NM_007218.3 657 c=>t >OriGene 5' read for NM_007218 unedited
GTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGTTGCCCGCCTTAGCCCC CGCCCCCGGCCGCGGCCCCGGGCCCTGCCCCGCGCGGCCCTGCCCGGCCCACCGAGCCCT GGTGTGGCAGCGGCTCATGGCGGCCGTGGGGCCCCCGCAGCAGCAGGTGCGGATGGCCCA TCAGCAGGTCTGGGCGGCGCTCGAAGTGGCGCTCCGGGTGCCCTGCCTTTACATCATCGA CGCCATCTTCAACTCCTACCCGGATTCCAGCCAAAGCCGGTTCTGCATCGTGCTCCAGAT CTTCCTCCGGCTCTTTGGTGTATTTGCATCCAGTATTGTTCTGATCTTGTCACAACGATC ACTTTTCAAGTTTTACACGTACAGCTCAGCCTTTCTGTTAGCTGCAACTTCAGTGTTGGT GAATTATTATGCTTCTTTGCACATTGACTTCTATGGTGCCTACAACACGTCAGCTTTTGG AATTGAGCTGCTTCCTCGAAAAGGTCCCTCGCTGTGGATGGCACTTATCGTTCTACAGCT AACATTTGGAATTGGATACGTTACACTACTCCAGATTCATTCCATCTATTCACAATTAAT TATTTTGGATCTCTTGGTTCCTGTAATAGGCTTAATCACAGAGCTACCATTACACATCAG AGAGACTTTACTGTTTACTTCTTCCTTGATTCTCACATTAAATACAGTGTTTGTCCTGGC AGTGAAACTGAAGTGGTTTTATTATTCCACACGATATGTTTATCTTTTGGTGAGGCACAT GTATCCGATTTATGGATTACAGTTATTGATGGAAGACACATGGGAGAGGNNATCGTTCCC AGACATACTACGAGTCTTTTTGCCTAACAGAGTACAGCTCAAGCTACAGTGNTAATGTAA CATCTAAAGGATGGCAAATGAAACTGATTCCTTTCTTATTTT >OriGene 3' read for NM_007218 unedited
AGCTTTGNACCCGCGGCCGCATNCTANAATCGAGTNTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAAGGGGAAAACATTTTTTTTTTTGTCC AATAATGGCCACAAATTTAAACGGGTCCCCAAAAAAACCAAAAGTATTTAAAGAGGTTTT TTTACAGTACCCCATCACAGTAAACGGAAAACCTTTCACAAATTCAACATTGATCCTGTT TTTGGGCTGGGTTACCCCCTGAAGGGGAAGGATTTTACTCCTTTTTGGATGAACTGAATT TTAAACAAATCCCTCAATCATTAAAAAAGGCTTTTTTCATCAGCCAGTATCATCATTAAA TTTTTCAACTGCTGCCCCTGGGGGCTGAAACACTCCATTTTTTTTTTTTTGAACATCATC ATCACAATCTGGACTGGCATTTTCGTTAAATTCCCTGGAAAAATAAAAAACAGTTTTTTT TACAGTTTCCTTTGGAGTTTCATTGGGGGGAAAAAATCCATTGGGGTAAAACACATTGGA ATTATCCTTGATATCATCTTCAAGGGATACTTTTTGAGGGCACATTGGACAAGTTTTTTG AATGTACAGCCTTTTCCGAAGGCAAAGTGCATGGAAATAATGATTACACGGGGTAATACG ACCAGATGTTGTAAACTCATGATAGCAAATTGCACATACTTCATTTATTTCTTGAAAGCG GCTCCCTTTTATTTCAGGAAGGGAATAAATTTTCTTCACGCAGTCCTCGATTAAAAATGT CTTCACCCATTTTTGGCTGTAAGTAAATGTAAAAATGCCTGTAGGCCAATATAAAAGCCG AATTTTACTTTCCACTAAACTATAGTGTAGCCCATTTCAACTTACAACCCAATTAAATCA TAATCCGCTGTGGACAACGAAAAACATATGCAAGCTTCCAAAGACTTTATACCTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007218 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007218.3, NP_009149.2 |
| RefSeq Size | 3312 bp |
| RefSeq ORF | 1995 bp |
| Locus ID | 11236 |
| UniProt ID | Q8WU17 |
| Domains | RING |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation
,P-H Lin, W-M Lan & L-Y Chau,
Oncogene doi:10.1038/onc.2012.244
[RNF139]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209442 | RNF139 (Myc-DDK-tagged)-Human ring finger protein 139 (RNF139) |
CNY 4,944.00 |
|
| RC209442L3 | Lenti ORF clone of Human ring finger protein 139 (RNF139), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC209442L4 | Lenti ORF clone of Human ring finger protein 139 (RNF139), mGFP tagged |
CNY 6,460.00 |
|
| RG209442 | RNF139 (tGFP-tagged) - Human ring finger protein 139 (RNF139) |
CNY 6,544.00 |
