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PDE10A (NM_006661) Human Untagged Clone
CAT＃: SC115943
PDE10A (untagged)-Human phosphodiesterase 10A (PDE10A), transcript variant 2
CNY 5,712.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001130690 edited
ACTCCGCGGCGTCCCCAGGGCGCCAGCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTC GGCTCCGACATGGAAGATGGACCTTCTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAG TGCTTCCTGAGCCCCAGTTTGACAGATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCC CAGGTATTAGATGAATTTGTATCTGAAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTG AAGAGGAAGAACAACAAATCAGAAGATGAATCAGCTCCTAAGGAAGTCAGCAGGTACCAA GATACGAATATGCAGGGAGTTGTATATGAACTAAACAGCTATATAGAACAACGGTTGGAC ACAGGAGGAGACAACCAGCTACTCCTCTATGAACTGAGCAGCATCATTAAAATAGCCACA AAAGCCGATGGATTTGCACTGTATTTCCTTGGAGAGTGCAATAATAGCCTGTGTATATTC ACGCCACCTGGGATAAAGGAAGGAAAACCCCGCCTCATCCCTGCTGGGCCCATCACTCAG GGCACCACCGTCTCTGCTTATGTGGCCAAGTCCAGGAAAACACTGCTAGTAGAAGACATC CTTGGAGATGAACGATTTCCAAGAGGTACTGGACTGGAATCAGGGACTCGTATCCAGTCT GTTCTTTGCTTACCAATTGTCACTGCAATTGGTGACTTGATTGGTATTCTCGAGCTGTAT CGGCACTGGGGCAAAGAAGCCTTCTGTCTTAGTCACCAGGAGGTTGCAACAGCAAATCTT GCCTGGGCTTCAGTAGCAATACATCAGGTGCAGGTATGCAGAGGCCTTGCCAAACAGACA GAATTGAATGACTTCCTACTCGACGTATCAAAAACATATTTTGATAACATAGTTGCAATA GATTCTCTACTTGAACACATAATGATATATGCAAAAAACCTGGTGAATGCCGATCGTTGT GCGCTTTTCCAGGTGGACCATAAGAACAAGGAGTTATATTCAGACCTTTTTGATATTGGA GAGGAAAAGGAAGGAAAACCTGTCTTCAAGAAGACCAAAGAGATAAGATTTTCAATTGAG AAAGGAATTGCTGGCCAAGTAGCAAGAACAGGGGAAGTCCTGAACATTCCAGATGCCTAT GCAGACCCACGCTTTAACAGAGAAGTAGACTTGTACACAGGCTACACCACGCGGAACATC CTGTGCATGCCCATCGTCAGCCGAGGCAGCGTGATAGGTGTGGTGCAGATGGTCAACAAA ATCAGTGGCAGTGCCTTCTCTAAAACAGATGAAAACAACTTCAAAATGTTTGCCGTCTTT TGTGCTTTAGCCTTACACTGTGCTAATATGTATCATAGAATTCGCCACTCAGAGTGCATT TACCGGGTAACGATGGAAAAGCTGTCCTACCATAGCATTTGTACTTCAGAAGAGTGGCAA GGTCTCATGCAATTCACCCTTCCCGTGCGTCTCTGCAAAGAAATTGAATTATTCCACTTT GACATTGGTCCTTTTGAAAACATGTGGCCTGGAATTTTTGTCTACATGGTTCATCGGTCC TGTGGGACATCCTGCTTTGAGCTTGAAAAGTTGTGTCGTTTTATTATGTCTGTGAAGAAG AACTATCGGCGGGTTCCTTATCACAACTGGAAGCATGCGGTCACTGTAGCACACTGCATG TATGCCATACTTCAGAACAATCACACGCTTTTCACAGACCTTGAGCGCAAAGGACTGCTG ATTGCGTGTCTGTGTCATGACCTGGACCACAGGGGCTTCAGTAACAGCTACCTGCAGAAG TTCGACCACCCTCTGGCCGCTCTCTACTCCACTTCCACCATGGAGCAGCACCACTTCTCC CAGACTGTGTCCATCCTCCAGTTGGAAGGGCACAATATCTTCTCCACTCTGAGCTCCAGT GAATATGAGCAGGTGCTTGAGATCATCCGCAAAGCCATCATTGCCACAGACCTTGCTTTA TACTTTGGAAACAGGAAGCAGTTGGAAGAGATGTACCAGACCGGATCACTAAACCTTAAT AATCAATCACATAGAGACCGTGTAATTGGTTTGATGATGACTGCCTGTGACCTTTGTTCT GTGACAAAACTGTGGCCCGTTACAAAATTGACGGCAAATGATATATATGCAGAATTCTGG GCTGAGGGTGATGAAATGAAGAAATTGGGAATACAGCCTATTCCTATGATGGACAGAGAC AAGAAGGATGAAGTCCCCCAAGGCCAGCTTGGGTTCTACAATGCCGTGGCCATTCCCTGC TATACAACCCTTACCCAGATCCTCCCTCCCACGGAGCCTCTTCTGAAAGCATGCAGGGAT AATCTCAGTCAGTGGGAGAAGGTGATTCGAGGGGAGGAGACTGCAACCTGGATTTCATCC CCATCCGTGGCTCAGAAGGCAGCTGCATCTGAAGATTGAGCACTGGTCACCCTGACACGC TGTCCCACCTACAGATCCTCATCTTGCTTCTTTGACATTCTTTTCCTTTTTTTGGGGGGG GTGGGGGGAACCTGCACCT >OriGene 5' read for NM_006661 unedited
NGGGGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCAGCTC CCTTGAGCGTCCCCACCAGCAGTAGTCACCGCGGCGGCGGTGGCAGCGGCGGCGGGCGGC GGCGGCTCTTCCTCTCGCCTGCGCTCCAGGGCTTGCTGCTTCCAGCCCGTGCCGGTCCCC GGCCGCCGCCGCCGCCCCGGCTCCCCCTTGGCCAGGCCGCCCGCCGCGCGGGCTCCCCCG GCTTCCCCGGCGCCGGCCCAGGCGGCGGCGGCCAAACTCCGCGGCGTCCCCAGGGCGCCA GCTTCGCCCTCGCCGCCGCGGCCGCGCTGCTCTTCGGCTCCGACATGGAAGATGGACCTT CTAATAATGCGAGCTGCTTCCGAAGGCTGACCGAGTGCTTCCTGAGCCCCAGTTTGACAG ATGAAAAAGTGAAGGCATATCTTTCTCTTCACCCCCAGGTATTAGATGAATTTGTATCTG AAAGTGTTAGTGCAGAGACAGTAGAGAAATGGCTGAAGAGGAAGAACAACAAATCAGAAG ATGAATCAGCTCCTAAGGAAGTCAGCAGGTACCAAGATACGAATATGCAGGGAGTTGTAT ATGAACTAAACAGCTATATAGAACAACGGTTGGACACAGGAGGAGACAACCAGCTACTCC TCTATGAACTGAGCAGCATCATTAAAATAGCCACAAAAGCCGATGGATTTGCACTGTATT TCCTTGGAGAGTGCAATAATAGCCTGTGTATATTCACGCCACCTGNGATAAAGGAAGGAA AACCCCGNCTCATCCCTGCTGGGCCCATCACTCAGGGCACCACCGTCTCTGCTTATGTGG CCAAGTCCAGGAAACACTGCTAGTAGAAGACTCCTTGGAGATGACGATTNCCAAGAGTAC TGGACTGGATCAC >OriGene 3' read for NM_006661 unedited
TAATGGACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTATTTTGTTCT TTATGCAAAGGGTTCAGTAAAACTGCCAANACAACAACAAAAACAATTTTAAAAACTGAC ATCTTTTGAACTGCTACTTGAAGTTCTGAGATTTATTGTAACATATACCTCATCTCTTCT CAAAAAGACAGGAAGTCTACTTCGTCTAGTGTTAAATTTATTGATCTCAGCCCTTTAGGT TGAACTTAAAGAATTATGTTTAGTCTAACTAAATTCATGAAGCTCTGAAATAAGAGTTTG ACGTTTTGCCATCATTTCTTACTCTGTAACCTCAACGACATTTGTCCTGAGGCTGTGGAC TACAACTCAAGTTAATTACAAGTAGGTCATACATGAACATTCACCATTCACAATAGTAAT GTGTAAAAATTCCTATTTATATCCAACAACATCAAAGCAACATTGATGTTAAAGCCCAAG TACAATACCATAATAGTACCATTTTAAACCCTTATTAGAAAGATACAATGGAAAAGTACC CCTTCTGGATAATTTTTGTCCATTTCCTTTAAGGCCTCAGCAATATTAGCCTATTAGAAA AGGCTGGTTTGCAAGTCAAATGGAGTCACTTGGCCAGCTGATTTCTGAACGTGGGGGTGG TCCTGGTTGCTCAGTGTCTATGATGCCTCACAGAAGAGATTGGCAGGAAGTCCTCTGCTT GACTTATTTATTTGATGGTACCTTCTTGAAGAGGTTTGCACCCCAGTTACCAGGTGCANG TTCCCCCCACCCCCCCCAAAAAAAGGAAAAAATGNTCAAAAGCCAGATGAGGATCTCGTA GTGGGACAGCGTGTCAAGGTGACCAGTGCTCAATCTTCAGATGCAGCTGCCCTCTGAGCC CCGNATGGGGATGAAAATCCAGTTGCAGGCTCCTCCCTCCAAAAACCTTTTCCCCCTGAC TGAGATATTACCTGCATGCGTTCAAAAGAGGCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006661 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006661.1, NP_006652.1 |
| RefSeq Size | 4576 bp |
| RefSeq ORF | 2340 bp |
| Locus ID | 10846 |
| UniProt ID | Q9Y233 |
| Domains | PDEase, GAF |
| Protein Families | Druggable Genome |
| Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
| Gene Summary | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (2) has an additional exon in the 5' region, which includes an in-frame AUG start codon, as compared to variant 1. The resulting isoform (2) has an alternate and shorter N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and ß-catenin-dependent TCF transcriptional activity
,Li, N;Lee, K;Xi, Y;Zhu, B;Gary, BD;Ramírez-Alcántara, V;Gurpinar, E;Canzoneri, JC;Fajardo, A;Sigler, S;Piazza, JT;Chen, X;Andrews, J;Thomas, M;Lu, W;Li, Y;Laan, DJ;Moyer, MP;Russo, S;Eberhardt, BT;Yet, L;Keeton, AB;Grizzle, WE;Piazza, GA;,
Oncogene. April 2014
,PubMed ID 24704829
[PDE10A]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211181 | PDE10A (Myc-DDK-tagged)-Human phosphodiesterase 10A (PDE10A), transcript variant 2 |
CNY 5,704.00 |
|
| RC211181L1 | Lenti ORF clone of Human phosphodiesterase 10A (PDE10A), transcript variant 2, Myc-DDK-tagged |
CNY 8,104.00 |
|
| RC211181L2 | Lenti ORF clone of Human phosphodiesterase 10A (PDE10A), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC211181L3 | Lenti ORF clone of Human phosphodiesterase 10A (PDE10A), transcript variant 2, Myc-DDK-tagged |
CNY 8,104.00 |
|
| RC211181L4 | Lenti ORF clone of Human phosphodiesterase 10A (PDE10A), transcript variant 2, mGFP tagged |
CNY 8,104.00 |
|
| RG211181 | PDE10A (tGFP-tagged) - Human phosphodiesterase 10A (PDE10A), transcript variant 2 |
CNY 7,304.00 |
