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MMP11 (NM_005940) Human Untagged Clone
CAT＃: SC116425
MMP11 (untagged)-Human matrix metallopeptidase 11 (stromelysin 3) (MMP11)
CNY 5,488.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SL-3; ST3; STMY3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116425 sequence for NM_005940 edited (data generated by NextGen Sequencing)
ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTG CTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGACGTCCACCAC CTCCATGCCGAGAGGAGGGGGCCACAGCCCTGGCATGCAGCCCTGCCCAGTAGCCCGGCA CCTGCCCCTGCCACGCAGGAAGCCCCCCGGCCTGCCAGCAGCCTCAGGCCTCCCCGCTGT GGCGTGCCCGACCCATCTGATGGGCTGAGTGCCCGCAACCGACAGAAGAGGTTCGTGCTT TCTGGCGGGCGCTGGGAGAAGACGGACCTCACCTACAGGATCCTTCGGTTCCCATGGCAG TTGGTGCAGGAGCAGGTGCGGCAGACGATGGCAGAGGCCCTAAAGGTATGGAGCGATGTG ACGCCACTCACCTTTACTGAGGTGCACGAGGGCCGTGCTGACATCATGATCGACTTCGCC AGGTACTGGCATGGGGACGACCTGCCGTTTGATGGGCCTGGGGGCATCCTGGCCCATGCC TTCTTCCCCAAGACTCACCGAGAAGGGGATGTCCACTTCGACTATGATGAGACCTGGACT ATCGGGGATGACCAGGGCACAGACCTGCTGCAGGTGGCAGCCCATGAATTTGGCCACGTG CTGGGGCTGCAGCACACAACAGCAGCCAAGGCCCTGATGTCCGCCTTCTACACCTTTCGC TACCCACTGAGTCTCAGCCCAGATGACTGCAGGGGCGTTCAACACCTATATGGCCAGCCC TGGCCCACTGTCACCTCCAGGACCCCAGCCCTGGGCCCCCAGGCTGGGATAGACACCAAT GAGATTGCACCGCTGGAGCCAGACGCCCCGCCAGATGCCTGTGAGGCCTCCTTTGACGCG GTCTCCACCATCCGAGGCGAGCTCTTTTTCTTCAAAGCGGGCTTTGTGTGGCGCCTCCGT GGGGGCCAGCTGCAGCCCGGCTACCCAGCATTGGCCTCTCGCCACTGGCAGGGACTGCCC AGCCCTGTGGACGCTGCCTTCGAGGATGCCCAGGGCCACATTTGGTTCTTCCAAGGTGCT CAGTACTGGGTGTACGACGGTGAAAAGCCAGTCCTGGGCCCCGCACCCCTCACCGAGCTG GGCCTGGTGAGGTTCCCGGTCCATGCTGCCTTGGTCTGGGGTCCCGAGAAGAACAAGATC TACTTCTTCCGAGGCAGGGACTACTGGCGTTTCCACCCCAGCACCCGGCGTGTAGACAGT CCCGTGCCCCGCAGGGCCACTGACTGGAGAGGGGTGCCCTCTGAGATCGACGCTGCCTTC CAGGATGCTGATGGCTATGCCTACTTCCTGCGCGGCCGCCTCTACTGGAAGTTTGACCCT GTGAAGGTGAAGGCTCTGGAAGGCTTCCCCCGTCTCGTGGGTCCTGACTTCTTTGGCTGT GCCGAGCCTGCCAACACTTTCCTCTGA Clone variation with respect to NM_005940.3 113 c=>t >OriGene 5' read for NM_005940 unedited
AAACTGGGATTTGTAATACGACTTTATATAGGCGGCCGACGAATTCGCACGAGGCCGGGG CGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATG CTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGACGTCCAC CACCTCCATGCCGAGAGGAGGGGGCCACAGCCCTGGCATGCAGCCCTGCCCAGTAGCCCG GCACCTGCCCCTGCCACGCAGGAAGCCCCCCGGCCTGCCAGCAGCCTCAGGCCTCCCCGC TGTGGCGTGCCCGACCCATCTGATGGGCTGAGTGCCCGCAACCGACAGAAGAGGTTCGTG CTTTCTGGCGGGCGCTGGGAGAAGACGGACCTCACCTACAGGATCCTTCGGTTCCCATGG CAGTTGGTGCAGGAGCAGGTGCGGCAGACGATGGCAGAGGCCCTAAAGGTATGGAGCGAT GTGACGCCACTCACCTTTACTGAGGTGCACGAGGGCCGTGCTGACATCATGATCGACTTC GCCAGGTACTGGCATGGGGACGACCTGCCGTTTGATGGGCCTGGGGGCATCCTGGCCCAT GCCTTCTTCCCCAAGACTCACCGAGAAGGGGATGTCCACTTCGACTATGATGAGACCTGG ACTATCGGGGATGACCAGGGCACAGACCTGCTGCAGGTGGCAGCCCATGAATTTGGCCAC GTGCTGGGGCTGCAGCACACAACAGCAGCCCAAGCCCTGATGTCCGCCTTCTACACCTTT CGCTACCCACTGAGTCTCAGCCCAGATGACTGCAGGGGCGTTCAACACCTATATGGCCAG CCCTGCCCACTGTCACCTCCAGACCCCAACCTTGGCCCCCAGCTGGGATAGACACCATGA GATGC >OriGene 3' read for NM_005940 unedited
ACCGGGCCGCAATCTAGTATCGAGCNTTTTCTTTTTTTTTTTTTTTTTTTTAAAAAACAA CTGTGTTTAATGACAATCCTCAGTTTAAAAAAAAAAAAGAAGAAGAAGGTTTATACACAC TGTACACACATTTACAATGGCTTTGGAGGATAGCAGTGCTGCGAAAAGGGCTTCAGGAGG ATCCGGCCTGGGACAGGATTGAGGTATGTTGCAGCCTCCAGGGCCTGGGGTCTCCTGCAT GAAAAATACCCCTCCCCATTTGACTGTGAACTTTTTGGCCTGGATTCTGGAGAACAGATT TCCAGGATTGTCAGCCAGAAGGCAGACAGATGCAGGCACCTACCAAGACCTGACCTCAGG AAGTGGCCCTGCCCTACAGCCCAGTTGCTCATCCAGGGCTGAAGGCCATGGGGCCCCAGC ACCCTTGCTTCAGTGCCAGCCCCTGGAAGGAACCTCACAACAGGGATACAGCAAGGACAC TCCAGTTCCCCCAGTCCTGCCATGGTGCTACCCTGAGGGACAGGGATGGAGACAGGGCAG CCAGGTTTGCCAGGACCTGCATAGCGGGCCCAAGACTGCCCTTCCTCTTAAGTCATGCCA AAGCCTCCCTGCCCAGTCTGAGACAGTCGCTGGCAGGTGACCACGACCTGCGTGGCCCTT CCCGCAGTTGTCATGGTGTTTGTACCCCACCCCATCTCCCTGAGGAGACATGGGCTAAGT CCCATGCCTGGTGCCCACAGCCACCAAGATGGCCATGGGTCTTTACCCTGATATTCGAGG CCTGCAAGGGTCATCACCCCTGAGGGCTTCCAGCCCATGTCATAGAAAGTGTTGGCAGCT CCGCCATCCAATATTCAGGACCACGAAACGGGAAGCCTTCAAGCCTTCCTTCAAGGTCAA CTCTCATAAGCGGCCGCCAGGATTAGCTAACATCACTTCTGAAGGAGGGGATTCCAAGGA CCCTTTCATAATGCCTTGGGGCAGTATGCTACACCGGGCTGGTGGATCCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005940 |
| Insert Size | 2160 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005940.3, NP_005931.2 |
| RefSeq Size | 2276 bp |
| RefSeq ORF | 1467 bp |
| Locus ID | 4320 |
| UniProt ID | P24347 |
| Domains | hemopexin, Peptidase_M10, ZnMc |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209223 | MMP11 (Myc-DDK-tagged)-Human matrix metallopeptidase 11 (stromelysin 3) (MMP11) |
CNY 5,488.00 |
|
| RC209223L1 | Lenti-ORF clone of MMP11 (Myc-DDK-tagged)-Human matrix metallopeptidase 11 (stromelysin 3) (MMP11) |
CNY 7,888.00 |
|
| RC209223L2 | Lenti-ORF clone of MMP11 (mGFP-tagged)-Human matrix metallopeptidase 11 (stromelysin 3) (MMP11) |
CNY 5,890.00 |
|
| RC209223L3 | Lenti-ORF clone of MMP11 (Myc-DDK-tagged)-Human matrix metallopeptidase 11 (stromelysin 3) (MMP11) |
CNY 5,890.00 |
|
| RC209223L4 | Lenti-ORF clone of MMP11 (mGFP-tagged)-Human matrix metallopeptidase 11 (stromelysin 3) (MMP11) |
CNY 5,890.00 |
|
| RG209223 | MMP11 (tGFP-tagged) - Human matrix metallopeptidase 11 (stromelysin 3) (MMP11) |
CNY 4,370.00 |
