SLC6A8 (NM_005629) Human Untagged Clone

Name: SLC6A8 (NM_005629) Human Untagged Clone
SKU: SC116601
Price: 4736.00

CAT＃: SC116601

SLC6A8 (untagged)-Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1

Datasheet

SDS

"NM_005629" in other vectors (6)

CNY 4,736.00

货期*

现货

规格

Cited in 3 publications.

Product images

经常一起买 (4)

TA351709

Rabbit Polyclonal Anti-SLC6A8 Antibody

CNY 1,999.00
CNY 3,280.00

TF81001

TurboFectin Transfection Reagent (1 mL in 1 vial)

CNY 4,090.00

CC100003

DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)

CNY 1,280.00

PRIMER

Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each

CNY 480.00

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CCDS1; CRT; CRTR; CT1; CTR5
Vector	pCMV6-XL4
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene ORF within SC116601 sequence for NM_005629 edited (data generated by NextGen Sequencing) ATGGCGAAGAAGAGCGCCGAGAACGGCATCTATAGCGTGTCCGGCGACGAGAAGAAGGGC CCCCTCATCGCGCCCGGGCCCGACGGGGCCCCGGCCAAGGGCGACGGCCCCGTGGGCCTG GGGACACCCGGCGGCCGCCTGGCCGTGCCGCCGCGCGAGACCTGGACGCGCCAGATGGAC TTCATCATGTCGTGCGTGGGCTTCGCCGTGGGCTTGGGCAACGTGTGGCGCTTCCCCTAC CTGTGCTACAAGAACGGCGGAGGTGTGTTCCTTATTCCCTACGTCCTGATCGCCCTGGTT GGAGGAATCCCCATTTTCTTCTTAGAGATCTCGCTGGGCCAGTTCATGAAGGCCGGCAGC ATCAATGTCTGGAACATCTGTCCCCTGTTCAAAGGCCTGGGCTACGCCTCCATGGTGATC GTCTTCTACTGCAACACCTACTACATCATGGTGCTGGCCTGGGGCTTCTATTACCTGGTC AAGTCCTTTACCACCACGCTGCCCTGGGCCACATGTGGCCACACCTGGAACACTCCCGAC TGCGTGGAGATCTTCCGCCATGAAGACTGTGCCAATGCCAGCCTGGCCAACCTCACCTGT GACCAGCTTGCTGACCGCCGGTCCCCTGTCATCGAGTTCTGGGAGAACAAAGTCTTGAGG CTGTCTGGGGGACTGGAGGTGCCAGGGGCCCTCAACTGGGAGGTGACCCTTTGTCTGCTG GCCTGCTGGGTGCTGGTCTACTTCTGTGTCTGGAAGGGGGTCAAATCCACGGGAAAGATC GTGTACTTCACTGCTACATTCCCCTACGTGGTCCTGGTCGTGCTGCTGGTGCGTGGAGTG CTGCTGCCTGGCGCCCTGGATGGCATCATTTACTATCTCAAGCCTGACTGGTCAAAGCTG GGGTCCCCTCAGGTGTGGATAGATGCGGGGACCCAGATTTTCTTTTCTTACGCCATTGGC CTGGGGGCCCTCACAGCCCTGGGCAGCTACAACCGCTTCAACAACAACTGCTACAAGGAC GCCATCATCCTGGCTCTCATCAACAGTGGGACCAGCTTCTTTGCTGGCTTCGTGGTCTTC TCCATCCTGGGCTTCATGGCTGCAGAGCAGGGCGTGCACATCTCCAAGGTGGCAGAGTCA GGGCCGGGCCTGGCCTTCATCGCCTACCCGCGGGCTGTCACGCTGATGCCAGTGGCCCCA CTCTGGGCTGCCCTGTTCTTCTTCATGCTGTTGCTGCTTGGTCTCGACAGCCAGTTTGTA GGTGTGGAGGGCTTCATCACCGGCCTCCTCGACCTCCTCCCGGCCTCCTACTACTTCCGT TTCCAAAGGGAGATCTCTGTGGCCCTCTGTTGTGCCCTCTGCTTTGTCATCGATCTCTCC ATGGTGACTGATGGCGGGATGTACGTCTTCCAGCTGTTTGACTACTACTCGGCCAGCGGC ACCACCCTGCTCTGGCAGGCCTTTTGGGAGTGCGTGGTGGTGGCCTGGGTGTACGGAGCT GACCGCTTCATGGACGACATTGCCTGTATGATCGGGTACCGACCTTGCCCCTGGATGAAA TGGTGCTGGTCCTTCTTCACCCCGCTGGTCTGCATGGGCATCTTCATCTTCAACGTTGTG TACTACGAGCCGCTGGTCTACAACAACACCTACGTGTACCCGTGGTGGGGTGAGGCCATG GGCTGGGCCTTCGCCCTGTCCTCCATGCTGTGCGTGCCGCTGCACCTCCTGGGCTGCCTC CTCAGGGCCAAGGGCACCATGGCTGAGCGCTGGCAGCACCTGACCCAGCCCATCTGGGGC CTCCACCACTTGGAGTACCGAGCTCAGGACGCAGATGTCAGGGGCCTGACCACCCTGACC CCAGTGTCCGAGAGCAGCAAGGTCGTCGTGGTGGAGAGTGTCATGTGA Clone variation with respect to NM_005629.3 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for NM_005629 unedited TCGCATTTGTATACGACNACTATAGGCGGCACGCGAATTCGCACGAGGCGACCCCGGCCC GGCCGTGCGGCCCGCCGGGGCCATAGGCGAAGAAGATCGCCGAGAACGGCATCTATAGCG TGTCCGGCGACGAGAAGAAGGGCCCCCTCATCGCGCCCGGGCCCGACGGGGCCCCGGCCA AGGGCGACGGCCCCGTGGGCCTGGGGACACCCGGCGGCCGCCTGGCCGTGCCGCCGCGCG AGACCTGGACGCGCCAGATGGACTTCATCATGTCGTGCGTGGGCTTCGCCGTGGGCTTGG GCAACGTGTGGCGCTTCCCCTACCTGTGCTACAAGAACGGCGGAGGTGTGTTCCTTATTC CCTACGTCCTGATCGCCCTGGTTGGAGGAATCCCCATTTTCTTCTTATAGATCTCGCTGG GCCAGTTCATGAAGGCCGGCAGCATCAATGTCTGGAACATCTGTCCCCTGTTCAAAGGCC TGGGCTACGCCTCCATGGTGATCGTCTTCTACTGCAACACCTACTACATCATGGTGCTGG CCTGAGGCTTCTATTACCTGGTCAAGTCCTTTACCACCACGCTGCCCTGAGCCACATGTG GCCACACCTGGAACACTCCCGACTGCGTGGAGATCTTCCGCCATGAAGACTGTGCCAATG CCAGCCTGGCCAACCTCACCTGTGACCAGCTTGCTGACCGCCGGTCCCCTGTCATCGAGT TCTGGGAGAACATAGTCTTGATGCTGTCTGAGGGACTGGNAGTGGCAGGGGCCCTCACTG GGATGTGACCCTTTGTCTGCTGGNCTGCTGGGTGCTGGTCTACTTCTGTGTCTGGAATGG GGGTCAATCCACGGNAAAGATCGNGTACTTCACTGCTACATTCCNCTACGTGGNCCTGGT CNTGCTGCTAGTGCCNTGGAATGCTGCTGCCTGNCGCCCTGNATGGCATCATTTACTATC TCAGCCTGACTGTNAAAAANCTGGGGTCCCTCCAGGGTGGA 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for NM_005629 unedited AAGCGATACGAGGTATCTGTGCCGCGCTCGANGTTCAATTTTTTTTTTTTTTTTTTGTGA TATTTTTGGCGTTTTATAAAAAGGAAAAATTGTTTTAGTGAGCACTCATGGTGCTTTCTC CCCTCCTCCCCCAGGCAGACCCCAAAAGTGTCAGGGAAAGGCAGGCCCCCTGGAGGGGTG CGGTGGGGCTGAAGCAGGGGCTGCTATGGCTACCATATGTGAGCTGGTGATGTGAGCTGA GTTGTCACATGACACTCTCCACCACGACGACCTTGCTGCTCTCGGACACTGGGGTCAGGG TGGTCAGGCCCCTGACATCTGCGTCCTGAGCTCGGTACTCCAAGTGGTGGAGGCCCCAGA TGGGCTGGGTCAGGTGCTGCCAGCGCTCATCCATGGTGCCCTTGGCCCTGAGGAGGCAGC CCAGGAGGTGCAGCGGCACGCACAGCATGGAGGACAGGGCGAAGGCCCAGCCCATGGCCT CACCCCACCACGGGTACACGTAGGTGTTGTTGTAGACCAGCGGCTCGTAGTACACAACGT TGAAGATGAAGATGCCCATGCAGACCAGCGGGGTGAAGAATGACCAGCACCATTTCATCC AGGGGCAAGGTCGGTACCCGATCATACAGGCAATGTCGTCCATGAAGCGGTCAGCTCCGT ACACCCAGGCCACCACCACGCACTCCCAAAAGGCCTGCCAGAGCAGGGTGGTGCCGCTGG CCGAGTAGTAGTCAAACAGCTGGAAGACGTACATCCCGCCCTCAGTCACCATGGAGAGAT CGATGACAAAACAGAGGGCACAACAGAAGGCCACAGAATATCTCCTTTGGAAACGAAATT TTAGGATGCCGGGAGG
Restriction Sites	NotI-NotI
ACCN	NM_005629
Insert Size	2000 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_005629.1, NP_005620.1
RefSeq Size	3917 bp
RefSeq ORF	1908 bp
Locus ID	6535
UniProt ID	P48029
Domains	SNF
Protein Families	Druggable Genome, Transmembrane
Gene Summary	The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (3)

The use of this cDNA Clones has been cited in the following citations:
Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1 ,null, Frontiers in Physiology ,PubMed ID 35837012 [SLC6A8]
Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome ,El-Kasaby, A;Kasture, A;Koban, F;Hotka, M;Asjad, HMM;Kubista, H;Freissmuth, M;Sucic, S;, Neuropharmacology ,PubMed ID 30885608 [SLC6A8]
Lack of evidence for synaptic high-affinity γ-hydroxybutyric acid (GHB) transport in rat brain synaptosomes and 11 Na+ -dependent SLC neurotransmitter transporters ,Thiesen, L;Frølund, B;Wellendorph, P;, J. Neurochem. ,PubMed ID 30570143 [SLC6A8]

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
TrueORF SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

Other Versions

SKU	Description	Size	Price
RC209828	SLC6A8 (Myc-DDK-tagged)-Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,728.00
RC209828L1	Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1, Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 7,128.00
RC209828L2	Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1, mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RC209828L3	Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1, Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RC209828L4	Lenti ORF clone of Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1, mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RG209828	SLC6A8 (tGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8), transcript variant 1	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,328.00

其它SLC6A8产品

Expression Plasmids

Lentiviral Particles

CRISPR

RNAi

Proteins

Antibodies