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LRRC32 (NM_005512) Human Untagged Clone
CAT＃: SC116699
LRRC32 (untagged)-Human leucine rich repeat containing 32 (LRRC32), transcript variant 1
CNY 7,400.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CPPRDD; D11S833E; GARP |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005512, the custom clone sequence may differ by one or more nucleotides
ATGAGACCCCAGATCCTGCTGCTCCTGGCCCTGCTGACCCTAGGCCTGGCTGCACAACACCAAGACAAAG TGCCCTGTAAGATGGTGGACAAGAAGGTCTCGTGCCAGGTTCTGGGCCTGCTCCAGGTCCCCTCGGTGCT CCCGCCAGACACTGAGACCCTTGATCTATCTGGGAACCAGCTGCGGAGTATCCTGGCCTCACCCCTGGGC TTCTACACAGCACTTCGTCACCTGGACCTGAGCACCAATGAGATCAGCTTCCTCCAGCCAGGAGCCTTCC AGGCCCTGACCCACCTGGAGCACCTCAGCCTGGCTCACAACCGGCTGGCGATGGCCACTGCGCTGAGTGC TGGTGGCCTGGGCCCCCTGCCACGCGTGACCTCCCTGGACCTGTCTGGGAACAGCCTGTACAGCGGCCTG CTGGAGCGGCTGCTGGGGGAGGCACCCAGCCTGCATACCCTCTCACTGGCGGAGAACAGTCTGACTCGCC TCACCCGCCACACCTTCCGGGACATGCCTGCGCTGGAGCAGCTTGACCTGCATAGCAACGTGCTGATGGA CATCGAGGATGGCGCCTTCGAGGGTCTGCCCCGCCTGACCCATCTCAACCTCTCCAGGAATTCCCTCACC TGCATCTCCGACTTCAGCCTCCAGCAGCTGCGGGTGCTAGACCTGAGCTGCAACAGCATCGAGGCCTTTC AGACGGCCTCCCAGCCCCAGGCTGAGTTCCAGCTCACCTGGCTTGACCTGCGGGAGAACAAACTGCTCCA TTTCCCCGACCTGGCCGCGCTCCCGAGACTCATCTACCTGAACTTGTCCAACAACCTCATCCGGCTCCCC ACAGGGCCACCCCAGGACAGCAAGGGCATCCACGCACCTTCCGAGGGCTGGTCAGCCCTGCCCCTCTCAG CCCCCAGCGGGAATGCCAGCGGCCGCCCCCTTTCCCAGCTCTTGAATCTGGATTTGAGCTACAATGAGAT TGAGCTCATCCCCGACAGCTTTCTTGAGCACCTGACCTCCCTGTGCTTCCTGAACCTCAGCAGAAACTGC TTGCGGACCTTTGAGGCCCGGCGCTTAGGCTCCCTGCCCTGCCTGATGCTCCTTGACTTAAGCCACAATG CCCTGGAGACACTGGAACTGGGCGCCAGAGCCCTGGGGTCTCTGCGGACGCTGCTCCTACAGGGCAATGC CCTGCGGGACCTGCCCCCATACACCTTTGCCAATCTGGCCAGCCTGCAGCGGCTCAACCTGCAGGGGAAC CGAGTCAGCCCCTGTGGGGGGCCAGATGAGCCTGGCCCCTCCGGCTGTGTGGCCTTCTCCGGCATCACCT CCCTCCGCAGCCTGAGCCTGGTGGATAATGAGATAGAGCTGCTCAGGGCAGGGGCCTTCCTCCACACCCC ACTGACTGAGCTGGACCTTTCTTCCAATCCTGGGCTGGAGGTGGCCACGGGGGCCTTGGGAGGCCTGGAG GCCTCCTTGGAGGTCCTGGCACTGCAGGGCAACGGGCTGATGGTCCTGCAGGTGGACCTGCCCTGCTTCA TCTGCCTCAAGCGGCTCAATCTTGCCGAGAACCGCCTGAGCCACCTTCCCGCCTGGACACAGGCTGTGTC ACTGGAGGTGCTGGACCTGCGAAACAACAGCTTCAGCCTCCTGCCAGGCAGTGCCATGGGTGGCCTGGAG ACCAGCCTCCGGCGCCTCTACCTGCAGGGGAATCCACTCAGCTGCTGCGGCAATGGCTGGCTGGCAGCCC AGCTGCACCAGGGCCGTGTGGACGTGGACGCCACCCAGGACCTGATCTGCCGCTTCAGCTCCCAGGAGGA GGTGTCCCTGAGCCACGTGCGTCCCGAGGACTGTGAGAAGGGGGGACTGAAGAACATCAACCTCATCATC ATCCTCACCTTCATACTGGTCTCTGCCATCCTCCTCACCACGCTGGCCGCCTGCTGCTGCGTCCGCCGGC AGAAGTTTAACCAACAGTATAAAGCCTAA >OriGene 5' read for NM_005512 unedited
TATCCCCCGCCCGTTGNCGCATAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGC AGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCG AATTCGGCACGAGGAGAGGAGCTGCGGCCGCGCTGAGCCAGAGCCATGAGACCCCAGATC CTGCTGCTCCTGGCCCTGCTGACCCTAGGCCTGGCTGCACAACACCAAGACAAAGTGCCC TGTAAGATGGTGGACAAGAAGGTCTCGTGCCAGGTTCTGGGCCTGCTCCAGGTCCCCTCG GTGCTCCCGCCAGACACTGAGACCCTTGATCTATCTGGGAACCAGCTGCGGAGTATCCTG GCCTCACCCCTGGGCTTCTACACGGCACTTCGTCACCTGGACCTGAGCACCAATGAGATC AGCTTCCTCCAGCCAGGAGCCTTCCAGGCCCTGACCCACCTGGAGCACCTCAGCCTGGCT CACAACCGGCTGGCGATGGCCACTGCGCTGAGTGCTGGTGGCCTGGGCCCCCTGCCACGC GTGACCTCCCTGGACCTGTCTGGGAACAGCCTGTACAGCGGCCTGCTGGAGCGGCTGCTG GGGGAGGCACCCAGCCTGCATACCCTCTCACTGGCGGAGAACAGTCTGACTCGCCTCACC CGCCACACCTTCCGGGACATGCCTGCGCTGGAGCAGCTTGACCTGCATAGCAACGTGCTG ATGGACATCGAGGATGGCGCCTTCGAGGGCCTGCCCCGCCTGACCCATCTCAACCTCTCC AGGAATTCCCTCACCTGCATCTCCGACTTCAGCCTCCAGCAGCTGCGGGTGCTAGACCTG AGCTGCACAGCATCGAGGCCTTTCAGACGGCTCCCAGCCCCAGCTGAGTCCAGCTCACCT GGCTTGACCTGCGGNAGAACAACTGCTTCATTCC >OriGene 3' read for NM_005512 unedited
GGAATACTATGNACGCGGCCGCATTCTAGNATCGAGTTTTTTTTTTTTTTTTTTTCTCCA AAATTAGTTTTTAATACATTCAGGTAGGTTATACAAAGAGTTGGTCCCGAGGCCTGGGCT GAGGCCTGGGCCCTGGGAAGTGACAGCAGCCCTGTGTAGTGTTTTCAAAGATCAGGCGTG GGGACCCACACCTTGGCCTCCAGGCCTAAGGAGGAGTGTTACGTGCAGTAGCACCCGTGG GTGTGATCCCAACCAGGACTGGGTCTGCCTGGGTGCTCCACACACCACCAGGGCCTAGCC CTGGCTCTGCCCATTGACTCTCCCTTAACTTCCTCTGGGCCTTGGTGTTCTCCTCTGTAA AATGGGGTGGAGAGAGTGGCATTTTCACTTTCTCGCACATTACTGAGCCCACATCATGAG CCAGACTGTGGGCCAAGCACAGGTAAGATGATGAAGACAGCAAAACAAGGTCTTGAGTTG GTCCCAGCACGTCCATTCTTCCCAGACACCTCATGACTCCCTGGTATGAGGGATGGGGGT CATCTGGGTGAGGCTTTTTACCTGTTTTTGGAAGAGGAAAAAAGATCCTGCCTGATGAGG CACAAAAAGGAAGTTTGGAGCCCCCATTATCTTGTGATGTGATAGCTGAGAAAAAGAATC ACTTCTGGTGCAAACCCCCAACTTACCCCCAAAAAAGGGGTCTTTTTTCCCCCGAGCTCT GTATAAGCTCTCCCCAATTTTAATTTCTTCCTAACCTCAGTTTCCCCATTTTTGCAAGGG GGGAGGTGGTTTTCTATATCTTAAATCCAGGCTCTGGTTCTTTTGGGAAAAGGGATGGGA GAATCCCGAACCCCTCAGGGACAGGGGAACCCCCCCCAGGGGGTGAAGGGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005512 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005512.1, NP_005503.1 |
| RefSeq Size | 4163 bp |
| RefSeq ORF | 1989 bp |
| Locus ID | 2615 |
| UniProt ID | Q14392 |
| Domains | LRRNT, LRR, LRR_RI, LRR_TYP, LRR_PS |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1-4 all encode the same isoform (a). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
GARP Is Regulated by miRNAs and Controls Latent TGF-Beta1 Production by Human Regulatory T Cells
,Gauthy, E;Cuende, J;Stockis, J;Huygens, C;Lethe, B;Collet, JF;Bommer, G;Coulie, PG;Lucas, S;,
PLoS One. 2013 Sep 30;8(9):e76186
,PubMed ID 24098777
[LRRC32]
|
|
GARP regulates the bioavailability and activation of TGFß
,Rui Wang, Jianghai Zhu, Xianchi Dong, Minlong Shi, Chafen Lu, and Timothy A. Springer,
Mol. Biol. Cell, Mar 2012; 23: 1129 - 1139.
[LRRC32]
|
|
Identification of a Regulatory T Cell Specific Cell Surface Molecule that Mediates Suppressive Signals and Induces Foxp3 Expression
,Rui Wang, Qi Wan, Lina Kozhaya, Hodaka Fujii, Derya Unutmaz,
PLoS ONE 3(7): e2705.
[LRRC32]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209831 | LRRC32 (Myc-DDK-tagged)-Human leucine rich repeat containing 32 (LRRC32), transcript variant 1 |
CNY 7,392.00 |
|
| RC209831L1 | Lenti ORF clone of Human leucine rich repeat containing 32 (LRRC32), transcript variant 1, Myc-DDK-tagged |
CNY 9,792.00 |
|
| RC209831L2 | Lenti ORF clone of Human leucine rich repeat containing 32 (LRRC32), transcript variant 1, mGFP tagged |
CNY 9,792.00 |
|
| RC209831L3 | Lenti ORF clone of Human leucine rich repeat containing 32 (LRRC32), transcript variant 1, Myc-DDK-tagged |
CNY 9,792.00 |
|
| RC209831L4 | Lenti ORF clone of Human leucine rich repeat containing 32 (LRRC32), transcript variant 1, mGFP tagged |
CNY 9,792.00 |
|
| RG209831 | LRRC32 (tGFP-tagged) - Human leucine rich repeat containing 32 (LRRC32), transcript variant 1 |
CNY 8,992.00 |
