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FOXG1 (NM_005249) Human Untagged Clone
CAT＃: SC116871
FOXG1 (untagged)-Human forkhead box G1 (FOXG1)
CNY 5,488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BF1; BF2; FHKL3; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C; HBF-1; HBF-2; HBF-3; HBF-G2; HBF2; HFK1; HFK2; HFK3; KHL2; QIN |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005249, the custom clone sequence may differ by one or more nucleotides
ATGCTGGACATGGGAGATAGGAAAGAGGTGAAAATGATCCCCAAGTCCTCGTTCAGCATCAACAGCCTGG TGCCCGAGGCGGTCCAGAACGACAACCACCACGCGAGCCACGGCCACCACAACAGCCACCACCCCCAGCA CCACCACCACCACCACCACCATCACCACCACCCGCCGCCGCCCGCCCCGCAACCGCCGCCGCCGCCGCAG CAGCAGCAGCCGCCGCCGCCGCCGCCCCCGGCACCGCAGCCCCCCCAGACGCGGGGCGCCCCGGCCGCCG ACGACGACAAGGGCCCCCAGCAGCTGCTGCTCCCGCCGCCGCCACCGCCACCACCGGCCGCCGCCCTGGA CGGGGCTAAAGCGGACGGGCTGGGCGGCAAGGGCGAGCCGGGCGGCGGGCCGGGGGAGCTGGCGCCCGTC GGGCCGGACGAGAAGGAGAAGGGCGCCGGCGCCGGGGGGGAGGAGAAGAAGGGGGCGGGCGAGGGCGGCA AGGACGGGGAGGGGGGCAAGGAGGGCGAGAAGAAGAACGGCAAGTACGAGAAGCCGCCGTTCAGCTACAA CGCGCTCATCATGATGGCCATCCGGCAGAGCCCCGAGAAGCGGCTCACGCTCAACGGCATCTACGAGTTC ATCATGAAGAACTTCCCTTACTACCGCGAGAACAAGCAGGGCTGGCAGAACTCCATCCGCCACAATCTGT CCCTCAACAAGTGCTTCGTGAAGGTGCCGCGCCACTACGACGACCCGGGCAAGGGCAACTACTGGATGCT GGACCCGTCGAGCGACGACGTGTTCATCGGCGGCACCACGGGCAAGCTGCGGCGCCGCTCCACCACCTCG CGGGCCAAGCTGGCCTTCAAGCGCGGTGCGCGCCTCACCTCCACCGGCCTCACCTTCATGGACCGCGCCG GCTCCCTCTACTGGCCCATGTCGCCCTTCCTGTCCCTGCACCACCCCCGCGCCAGCAGCACTTTGAGTTA CAACGGCACCACGTCGGCCTACCCCAGCCACCCCATGCCCTACAGCTCCGTGTTGACTCAGAACTCGCTG GGCAACAACCACTCCTTCTCCACCGCCAACGGCCTGAGCGTGGACCGGCTGGTCAACGGGGAGATCCCGT ACGCCACGCACCACCTCACGGCCGCCGCGCTAGCCGCCTCGGTGCCCTGCGGCCTGTCGGTGCCCTGCTC TGGGACCTACTCCCTCAACCCCTGCTCCGTCAACCTGCTCGCGGGCCAGACCAGTTACTTTTTCCCCCAC GTCCCGCACCCGTCAATGACTTCGCAGAGCAGCACGTCCATGAGCGCCAGGGCCGCGTCCTCCTCCACGT CGCCGCAGGCCCCCTCGACCCTGCCCTGTGAGTCTTTAAGACCCTCTTTGCCAAGTTTTACGACGGGACT GTCTGGGGGACTGTCTGATTATTTCACACATCAAAATCAGGGGTCTTCTTCCAACCCTTTAATACATTAA >OriGene 5' read for NM_005249 unedited
TCACCATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGTACAGTTGGG AGCGAGGGAGCTTCACCCCCGGGGCGGTGGTTGTTTCTTTTTTCTTTCTTTCTTTTTTCT TTTCCTTTTTTTTTTTTTTTCTAATTCCTGAGGGGTGGTTGCTGCTTTTGCTACATGACT TGCCAGCGCCCGAGCCTGCGGTCCAACTGCGCTGCTGCCGGAGCGCTCAGTGCCGCCGCT GCCGCCCGCGCCCCCCGCGCCCCGTTCGGCACCCACCGGTCGCCGCCGCCCGCCGCGCCG CTGTCCCGCTCCCGCGCCGCCGCCGCCGTTTCCCCCCGACGACTGGGTGATGCTGGACAT GGGAGATAGGAAAGAGGTGAAAATGATCCCCAAGTCCTCGTTCAGCATCAACAGCCTGGT GCCCGAGGCGGTCCAGAACGACAACCACCACGCGAGCCACGGCCACCACAACAGCCACCA CCCCCAGCACCACCACCACCACCACCACCATTACCACCACCCGCCGCCGCCCGCCCCGCA ACCGCCGCCGCCGCCGCAGCAGCAGCAGCCGCCGCCGCCGCCGCCCCCGGCACCGCAGCC CCCCCAGACGCGGGGCGCCCCGGCCGCCGACGACGACAAGGGCCCCCAGCAGCTGCTGCT CCCGCCGCCGNCACCGNCACCACCGGCCGNCGCCCTGGACGGGGCTAAAGNCGACGGGCT GGGCGGCAAGGGCGAGCCGGGCGGCGGGCCGGGGGGAGCTGGCGCCCCGTCGGCCGGACG AGAAGGAAAGGCGCCGGCGCCCGGGGGGAGGAAAAAAGGGGGCGGGCNAGGCGNNNAAGA CGGGGAAGGGGGCAAGGAGGCCCAAAAAAAACCGCAGTTCCAAAAACCCCGNTCAATTCA ACCGCTAATATGATGGCCATCGGCAAACCCCAAA >OriGene 3' read for NM_005249 unedited
NCCGTTGCGGGGATAGTTTGTGTGTGTGGATGGAAACGTTTTGTAGGGACGTACCGGGCA TATGACCACGAGGTCACAGTCAGGAAATTTTAAGACAACATTAACAATGACTCAAATTTA TGCGGCATTTGCGCAACACAGGTTACATATTTGCAAGGTTTACCTATAAGTACAATAGGT ATTAACATTTCACTACATTTAGAAAAAATAAAAGTGACCTGTTAGTGACCACATACATCA AAATATACACAACACAAACTGAAGGCAATCGTTAATTTTGTCCCCTTCTGATTCAATTGA ATGGGCAGTGTTGCCAACTGAAACAACTTTCCTTTTTGTTTGTTTTAATACTTAGTATAC CAAGTGCATTTTCTAGAACCCAATCTTTGGTCTAAAAGTAAACAAAAGAAAAAAAAACAG TTCTTTAAAGAAAAGGACAAAACAATAAATGGCCAAAATAATTTCTTGGGCACCTTTACT ACGAATGCTTTTTAAATACAAATTACAGTTTAACATTTTAAAATTCTCCCCATAATTTAG GTTGTTCTCAAGGTCTGCGTCCACCATATAGTTCCATGATAACTTATAATACTGCACACA TGGAAATCTGGCGGCTCTTAGAGATAGACTTGTCAGGTTTGAATGAAATGGCAAAGCAGT CACTATTTAGATACACATTCTACTATAATTTGACTTCCAAACCTTATATTCTACAATGTA TTCTCCCCACATTGCACCTCGCTGACACTTCACACCTTGNTAGAATAATAAACAACCCTA GAGACTGGACAAACGTACAGGAATGGGAAGGGGGGGCCTAAATAAAAAATAACCTGGACT TATTTTTTTAATTATCATTTAACATGCAAATGTGTGTAAACGTTTACTTTACAGCTTGTT CCCAGGTATGTTAATGTATTAAAGGGTTGAAAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005249 |
| Insert Size | 2940 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005249.3, NP_005240.3 |
| RefSeq Size | 2600 bp |
| RefSeq ORF | 1470 bp |
| Locus ID | 2290 |
| UniProt ID | P55316 |
| Domains | FH |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
FGF signaling is strictly required to maintain early telencephalic precursor cell survival
,null,
Development (Cambridge, England)
,PubMed ID 19542358
[FOXG1]
|
|
FGF signaling is strictly required to maintain early telencephalic precursor cell survival
,Hunki Paek, Grigoriy Gutin, and Jean M. Hébert,
Development, Jul 2009; 136: 2457 - 2465.
[FOXG1]
|
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| RC207964L2 | Lenti ORF clone of Human forkhead box G1 (FOXG1), mGFP tagged |
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| RC207964L3 | Lenti ORF clone of Human forkhead box G1 (FOXG1), Myc-DDK-tagged |
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| RC207964L4 | Lenti ORF clone of Human forkhead box G1 (FOXG1), mGFP tagged |
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| RG207964 | FOXG1 (tGFP-tagged) - Human forkhead box G1 (FOXG1) |
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