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Plakophilin 2 (PKP2) (NM_004572) Human Untagged Clone
CAT＃: SC117285
PKP2 (untagged)-Human plakophilin 2 (PKP2), transcript variant 2b
CNY 6,464.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARVD9 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004572, the custom clone sequence may differ by one or more nucleotides
ATGGCAGCCCCCGGCGCCCCAGCTGAGTACGGCTACATCCGGACCGTCCTGGGCCAGCAGATCCTGGGAC AACTGGACAGCTCCAGCCTGGCGCTGCCCTCCGAGGCCAAGCTGAAGCTGGCGGGGAGCAGCGGCCGCGG CGGCCAGACAGTCAAGAGCCTGCGGATCCAGGAGCAGGTGCAGCAGACCCTCGCCCGGAAGGGCCGCAGC TCCGTGGGCAACGGAAATCTTCACCGAACCAGCAGTGTTCCTGAGTATGTCTACAACCTACACTTGGTTG AAAATGATTTTGTTGGAGGCCGTTCCCCTGTTCCTAAAACCTATGACATGCTAAAGGCTGGCACAACTGC CACTTATGAAGGTCGCTGGGGAAGAGGAACAGCACAGTACAGCTCCCAGAAGTCCGTGGAAGAAAGGTCC TTGAGGCATCCTCTGAGGAGACTGGAGATTTCTCCTGACAGCAGCCCGGAGAGGGCTCACTACACGCACA GCGATTACCAGTACAGCCAGAGAAGCCAGGCTGGGCACACCCTGCACCACCAAGAAAGCAGGCGGGCCGC CCTCCTAGTGCCACCGAGATATGCTCGTTCCGAGATCGTGGGGGTCAGCCGTGCTGGCACCACAAGCAGG CAGCGCCACTTTGACACATACCACAGACAGTACCAGCATGGCTCTGTTAGCGACACCGTTTTTGACAGCA TCCCTGCCAACCCGGCCCTGCTCACGTACCCCAGGCCAGGGACCAGCCGCAGCATGGGCAACCTCTTGGA GAAGGAGAACTACCTGACGGCAGGGCTCACTGTCGGGCAGGTCAGGCCGCTGGTGCCCCTGCAGCCCGTC ACTCAGAACAGGGCTTCCAGGTCCTCCTGGCATCAGAGCTCCTTCCACAGCACCCGCACGCTGAGGGAAG CTGGGCCCAGTGTCGCCGTGGATTCCAGCGGGAGGAGAGCGCACTTGACTGTCGGCCAGGCGGCCGCAGG GGGAAGTGGGAATCTGCTCACTGAGAGAAGCACTTTCACTGACTCCCAGCTGGGGAATGCAGACATGGAG ATGACTCTGGAGCGAGCAGTGAGTATGCTCGAGGCAGACCACATGCTGCCATCCAGGATTTCTGCTGCAG CTACTTTCATACAGCACGAGTGCTTCCAGAAATCTGAAGCTCGGAAGAGGGTTAACCAGCTTCGTGGCAT CCTCAAGCTTCTGCAGCTCCTAAAAGTTCAGAATGAAGACGTTCAGCGAGCTGTGTGTGGGGCCTTGAGA AACTTAGTATTTGAAGACAATGACAACAAATTGGAGGTGGCTGAACTAAATGGGGTACCTCGGCTGCTCC AGGTGCTGAAGCAAACCAGAGACTTGGAGACTAAAAAACAAATAACAGACCATACAGTCAATTTAAGAAG TAGGAATGGCTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGG ATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTTTGCTGTGGAATTTGTCATCTAATGACA AACTCAAGAATCTCATGATAACAGAAGCATTGCTTACGCTGACGGAGAATATCATCATCCCCTTTTCTGG GTGGCCTGAAGGAGACTACCCAAAAGCAAATGGTTTGCTCGATTTTGACATATTCTACAACGTCACTGGA TGCCTAAGAAACATGAGTTCTGCTGGCGCTGATGGGAGAAAAGCGATGAGAAGATGTGACGGACTCATTG ACTCACTGGTCCATTATGTCAGAGGAACCATTGCAGATTACCAGCCAGATGACAAGGCCACGGAGAATTG TGTGTGCATTCTTCATAACCTCTCCTACCAGCTGGAGGCAGAGCTCCCAGAGAAATATTCCCAGAATATC TATATTCAAAACCGGAATATCCAGACTGACAACAACAAAAGTATTGGATGTTTTGGCAGTCGAAGCAGGA AAGTAAAAGAGCAATACCAGGACGTGCCGATGCCGGAGGAAAAGAGCAACCCCAAGGGCGTGGAGTGGCT GTGGCATTCCATTGTTATAAGGATGTATCTGTCCTTGATCGCCAAAAGTGTCCGCAACTACACACAAGAA GCATCCTTAGGAGCTCTGCAGAACCTCACGGCCGGAAGTGGACCAATGCCGACATCAGTGGCTCAGACAG TTGTCCAGAAGGAAAGTGGCCTGCAGCACACCCGAAAGATGCTGCATGTTGGTGACCCAAGTGTGAAAAA GACAGCCATCTCGCTGCTGAGGAATCTGTCCCGGAATCTTTCTCTGCAGAATGAAATTGCCAAAGAAACT CTCCCTGATTTGGTTTCCATCATTCCTGACACAGTCCCGAGTACTGACCTTCTCATTGAAACTACAGCCT CTGCCTGTTACACATTGAACAACATAATCCAAAACAGTTACCAGAATGCACGCGACCTTCTAAACACCGG GGGCATCCAGAAAATTATGGCCATTAGTGCAGGCGATGCCTATGCCTCCAACAAAGCAAGTAAAGCTGCT TCCGTCCTTCTGTATTCTCTGTGGGCACACACGGAACTGCATCATGCCTACAAGAAGGCTCAGTTTAAGA AGACAGATTTTGTCAACAGCCGGACTGCCAAAGCCTACCACTCCCTTAAAGACTGA >OriGene 5' read for NM_004572 unedited
NTTTTTCGNAATTATGTATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCAG CTCGGTCGCCCCCACCGGCCCCATGGCAGCCCCCGGCGCCCCAGCTGAGTACGGCTACAT CCGGACCGTCCTGGGCCAGCAGATCCTGGGACAACTGGACAGCTCCAGCCTGGCGCTGCC CTCCGAGGCCAAGCTGAAGCTGGCGGGGAGCAGCGGCCGCGGCGGCCAGACAGTCAAGAG CCTGCGGATCCAGGAGCAGGTGCAGCAGACCCTCGCCCGGAAGGGCCGCAGCTCCGTGGG CAACGGAAATCTTCACCGAACCAGCAGTGTTCCTGAGTATGTCTACAACCTACACTTGGT TGAAAATGATTTTGTTGGAGGCCGTTCCCCTGTTCCTAAAACCTATGACATGCTAAAGGC TGGCACAACTGCCACTTATGAAGGTCGCTGGGGAAGAGGAACAGCACAGTACAGCTCCCA GAAGTCCGTGGAAGAAAGGTCCTTGAGGCATCCTCTGAGGAGACTGGAGATTTCTCCTGA CAGCAGCCCGGAGAGGGCTCACTACACGCACAGCGATTACCAGTACAGCCAGAGAAGCCA GGCTGGGCACACCCTGCACCACCAAGAAAGCAGGCGGGCCGCCCTCCTAGTGCCACCGAG ATATGCTCGTTCCGAGATCGTGGNGGTCAGCCGTGCTGGCACCACAAGCAGGCAGCGCCA CTNTGACACATACCACAGACAGTACCAGCATGGCTCTGTTAGCGACACCGTTTTTGACAG CATCCCTGCCAACCCGGCCCTGCTCACGTACCCCCAGCCAGGGACCAGCCGCAGCATGGG CAACCTCTGGNAGAAGGAGAACTACCTCGACGCAGGNCTCACTGTCGGCCCAGTCAGCCC GCTGGTGCCCCTGCAGCCGTCACTCAGAACAGGCTTTCCAGTCCTCCTGGCATAAC >OriGene 3' read for NM_004572 unedited
TACCTAGCTTCNNGTCNAGGTCGAGTTTATTACTTTTTTTTTTAAATTATCGAATGCTTT ATTAATGCCTTAAAAAACACAAAAGTTCTGAACACACATTTATTATCTGGAGGAATAAAT GCACTCCAAATGCTTATCATCAGAACTCTGGAAAAAGAATATAAATTCTCTCCAGTATTT TAAAAATTGGTATCTAAATAATTGCGGTGGGAACTAGGTTAGCAACCTAAGTTGGCTTCA TTCAGCTTTTAAAATTGAAAAAAAATTGCTTCAAATATAATAAAGACTTAAGTACACATT CAAAATTTATTTTCTGTTACAGTTTTCTTGCCAAAAGGAGTTGAAGAATTTTTTTGCTTA TCTTACTTAGGACAAATGTTGTCAGATTAAAAAAAAAAATAACAGAATAGTAGTTGTAAA GACTAACTCTATATGAATGGTTCTAATCATAGCGCAGTTAAAACAACATTTAATGTACAT TCATTTCGCTGGATGATGTCACCCATTTAAAATATCACGATTTCCCATATCATCGCTGGA TGGTCTTGACACATTCTTACATCTTTTTCAACATGACTTCTTCCACTTTCCTTCTCTAGA GTTTTCTTGAGTTAAAATACTGGTCTTGCAGAAAACATTTGCCATCCAGCGGCCCCGCGA TATTTGTTAACCGGCGGGGCAAGGCTGCGCTGGCTGCCCATGCCCCTCATTATCCTGAAC CCGCTTTCCCCCGCCCCACGCTGGCCCCCCTCCCTGTTCCCGGGTCTCCCTCCTTTTCCC CCTCCCATTCGATTCTTCTTTTTCCTATTCCCGGCCTCGCCCCCCGACCCCCCACCCGCC TCCGTCTTATCCCCCGCCCGCGACCATTATGCCCCCACGTTTCTTTCCCGCCTCCCCTTC CCCCAATTTGTCTTTTTTTTTCTGCCCCCCCCCCGTCCCTTTTCCGCCCCTTTTTGTTCA TTCCCCCCCTCAATCCACACCTAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004572 |
| Insert Size | 4230 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004572.2, NP_004563.1 |
| RefSeq Size | 4439 bp |
| RefSeq ORF | 2646 bp |
| Locus ID | 5318 |
| UniProt ID | Q99959 |
| Domains | Armadillo_seg |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
| Gene Summary | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008] Transcript Variant: This transcript variant (2b) represents the longer transcript variant and encodes the longer isoform. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218592 | PKP2 (Myc-DDK-tagged)-Human plakophilin 2 (PKP2), transcript variant 2b |
CNY 9,310.00 |
|
| RC218592L3 | Lenti-ORF clone of PKP2 (Myc-DDK-tagged)-Human plakophilin 2 (PKP2), transcript variant 2b |
CNY 11,210.00 |
|
| RC218592L4 | Lenti-ORF clone of PKP2 (mGFP-tagged)-Human plakophilin 2 (PKP2), transcript variant 2b |
CNY 11,210.00 |
|
| RG218592 | PKP2 (tGFP-tagged) - Human plakophilin 2 (PKP2), transcript variant 2b |
CNY 8,696.00 |
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