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CD163 (NM_004244) Human Untagged Clone
CAT＃: SC117495
CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 1
CNY 8,056.00
| Cited in 6 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | M130; MM130; SCARI1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004244 edited
AACATTTCTAGGGAATAATACAAGAAGATTTAGGAATCATTGAAGTTATAAATCTTTGGA ATGAGCAAACTCAGAATGGTGCTACTTGAAGACTCTGGATCTGCTGACTTCAGAAGACAT TTTGTCAACTTGAGTCCCTTCACCATTACTGTGGTCTTACTTCTCAGTGCCTGTTTTGTC ACCAGTTCTCTTGGAGGAACAGACAAGGAGCTGAGGCTAGTGGATGGTGAAAACAAGTGT AGCGGGAGAGTGGAAGTGAAAGTCCAGGAGGAGTGGGGAACGGTGTGTAATAATGGCTGG AGCATGGAAGCGGTCTCTGTGATTTGTAACCAGCTGGGATGTCCAACTGCTATCAAAGCC CCTGGATGGGCTAATTCCAGTGCAGGTTCTGGACGCATTTGGATGGATCATGTTTCTTGT CGTGGGAATGAGTCAGCTCTTTGGGATTGCAAACATGATGGATGGGGAAAGCATAGTAAC TGTACTCACCAACAAGATGCTGGAGTGACCTGCTCAGATGGATCCAATTTGGAAATGAGG CTGACGCGTGGAGGGAATATGTGTTCTGGAAGAATAGAGATCAAATTCCAAGGACGGTGG GGAACAGTGTGTGATGATAACTTCAACATAGATCATGCATCTGTCATTTGTAGACAACTT GAATGTGGAAGTGCTGTCAGTTTCTCTGGTTCATCTAATTTTGGAGAAGGCTCTGGACCA ATCTGGTTTGATGATCTTATATGCAACGGAAATGAGTCAGCTCTCTGGAACTGCAAACAT CAAGGATGGGGAAAGCATAACTGTGATCATGCTGAGGATGCTGGAGTGATTTGCTCAAAG GGAGCAGATCTGAGCCTGAGACTGGTAGATGGAGTCACTGAATGTTCAGGAAGATTAGAA GTGAGATTCCAAGGAGAATGGGGGACAATATGTGATGACGGCTGGGACAGTTACGATGCT GCTGTGGCATGCAAGCAACTGGGATGTCCAACTGCCGTCACAGCCATTGGTCGAGTTAAC GCCAGTAAGGGATTTGGACACATCTGGCTTGACAGCGTTTCTTGCCAGGGACATGAACCT GCTATCTGGCAATGTAAACACCATGAATGGGGAAAGCATTATTGCAATCACAATGAAGAT GCTGGCGTGACATGTTCTGATGGATCAGATCTGGAGCTAAGACTTAGAGGTGGAGGCAGC CGCTGTGCTGGGACAGTTGAGGTGGAGATTCAGAGACTGTTAGGGAAGGTGTGTGACAGA GGCTGGGGACTGAAAGAAGCTGATGTGGTTTGCAGGCAGCTGGGATGTGGATCTGCACTC AAAACATCTTATCAAGTGTACTCCAAAATCCAGGCAACAAACACATGGCTGTTTCTAAGT AGCTGTAACGGAAATGAAACTTCTCTTTGGGACTGCAAGAACTGGCAATGGGGTGGACTT ACCTGTGATCACTATGAAGAAGCCAAAATTACCTGCTCAGCCCACAGGGAACCCAGACTG GTTGGAGGGGACATTCCCTGTTCTGGACGTGTTGAAGTGAAGCATGGTGACACGTGGGGC TCCATCTGTGATTCGGACTTCTCTCTGGAAGCTGCCAGCGTTCTATGCAGGGAATTACAG TGTGGCACAGTTGTCTCTATCCTGGGGGGAGCTCACTTTGGAGAGGGAAATGGACAGATC TGGGCTGAAGAATTCCAGTGTGAGGGACATGAGTCCCATCTTTCACTCTGCCCAGTAGCA CCCCGCCCAGAAGGAACTTGTAGCCACAGCAGGGATGTTGGAGTAGTCTGCTCAAGATAC ACAGAAATTCGCTTGGTGAATGGCAAGACCCCGTGTGAGGGCAGAGTGGAGCTCAAAACG CTTGGTGCCTGGGGATCCCTCTGTAACTCTCACTGGGACATAGAAGATGCCCATGTTCTT TGCCAGCAGCTTAAATGTGGAGTTACAGAGGGATCCCCAGGAGGAGCACGTTTTGGAAAA GGAAATGGTCAGATCTGGAGGCATATGTTTCACTGCACTGGGACTGAGCAGCACATGGGA GATTGTCCTGTAACTGCTCTAGGTGCTTCATTATGTCCTTCAGAGCAAGTGGCCTCTGTA ATCTGCTCAGGAAACCAGTCCCAAACACTGTCCTCGTGCAATTCATCGTCTTTGGGCCCA ACAAGGCCTACCATTCCAGAAGAAAGTGCTGTGGCCTGCATAGAGAGTGGTCAACTTCGC CTGGTAAATGGAGGAGGTCGCTGTGCTGGGAGAGTAGAGATCTATCATGAGGGCTCCTGG GGCACCATCTGTGATGACAGCTGGGACCTGAGTGATGCCCACGTGGTTTGCAGACAGCTG GGCTGTGGAGAGGCCATTAATGCCACTGGTTCTGCTCATTTTGGGGAAGGAACAGGGCCC ATCTGGCTGGATGAGATGAAATGCAATGGAAAAGAATCCCGCATTTGGCAGTGCCATTCA CACGGCTGGGGGCAGCAAAATTGCAGGCACAAGGAGGATGCGGGAGTTATCTGCTCAGAA TTCATGTCTCTGAGACTGACCAGTGAAGCCAGCAGAGAGGCCTGTGCAGGGCGTCTGGAA GTTTTTTACAATGGAGCTTGGGGCACTGTTGGCAAGAGTAGCATGTCTGAAACCACTGTG GGTGTGGTGTGCAGGCAGCTGGGCTGTGCAGACAAAGGGAAAATCAACCCTGCATCTTTA GACAAGGCCATGTCCATTCCCATGTGGGTGGACAATGTTCAGTGTCCAAAAGGACCTGAC ACGCTGTGGCAGTGCCCATCATCTCCATGGGAGAAGAGACTGGCCAGCCCCTCGGAGGAG ACCTGGATCACATGTGACAACAAGATAAGACTTCAGGAAGGACCCACTTCCTGTTCTGGA CGTGTGGAGATCTGGCATGGAGGTTCCTGGGGGACAGTGTGTGATGACTCTTGGGACTTG GACGATGCTCAGGTGGTGTGTCAACAACTTGGCTGTGGTCCAGCTTTGAAAGCATTCAAA GAAGCAGAGTTTGGTCAGGGGACTGGACCGATATGGCTCAATGAAGTGAAGTGCAAAGGG AATGAGTCTTCCTTGTGGGATTGTCCTGCCAGACGCTGGGGCCATAGTGAGTGTGGGCAC AAGGAAGACGCTGCAGTGAATTGCACAGATATTTCAGTGCAGAAAACCCCACAAAAAGCC ACAACAGGTCGCTCATCCCGTCAGTCATCCTTTATTGCAGTCGGGATCCTTGGGGTTGTT CTGTTGGCCATTTTCGTCGCATTATTCTTCTTGACTAAAAAGCGAAGACAGAGACAGCGG CTTGCAGTTTCCTCAAGAGGAGAGAACTTAGTCCACCAAATTCAATACCGGGAGATGAAT TCTTGCCTGAATGCAGATGATCTGGACCTAATGAATTCCTCAGGAGGCCATTCTGAGCCA CACTGAAAAGGAAAATGGGAATTTATAACCCAGTGAGTTCAGCCTTTAAGATACCTTGAT GAAGACCTGGACTATTGAATGGAGCAGAAATTCACCTCTCTCACTGACTATTACAGTTGC ATTTTTATGGAGTTCTTCTTCTCCTAGGATTCCTAAGACTGCTGCTGAATTTATAAAAAT TAAGTTTGTGAATGTGACTACTTAGTGGTGTATATGAGACTTTCAAGGGAATTAAATAAA TAAATAAGAATGTT >OriGene 5' read for NM_004244 unedited
TAGGGCGGCAAACCCATTCGGCACGAGGAACATTTCTAGGGAATAATACAAGAAGATTTA GGAATCATTGAAGTTATAAATCTTTGGAATGAGCAAACTCAGAATGGTGCTACTTGAAGA CTCTGGATCTGCTGACTTCAGAAGACATTTTGTCAACTTGAGTCCCTTCACCATTACTGT GGTCTTACTTTTTATTGCCTGTTTTGTCACCAGTTCTCTTGGAGGAACAGACAAGGAGCT GAGGCTAGTGGATGGTGAAAACAAGTGTAGCGGGAGAGTGGAAGTGAAAGTCCAGGAGGA GTGGGGAACGGTGTGTAATAATGGCTGGAGCATGGAAGCGGTCTCTGTGATTTGTAACCA GCTGGGATGTCCAACTGCTATCAAAGCCCCTGGATGGGCTAATTCCAGTGCAGGTTCTGG ACGCATTTGGATGGATCATGTTTCTTGTCGTGGGAATGAGTCAGCTCTTTGGGATTGCAA ACATGATGGATGGGGAAAGCATAGTAACTGTACTCACCAACAAGATGCTGGAGTGACCTG CTCAGATGGATCCAATTTGGAAATGAGGCTGACGCGTGGAGGGAATATGTGTTCTGGAAG AATAGAGATCAAATTCCAAGGACGGTGGGGAACAGTGTGTGATGATAACTTCAACATAGA TCATGCATCTGTCATTTGTAGACAACTTGAATGTGGAAGTGCTGTCAGTTTCTCTGGTTC ATCTAATTTTGGAGAAGGCTCTGGACCAATCTGGTTTGATGATCTTATATGCAACGGAAA TGAGTCAGCTCTCTGGAACTGCAAACATCAAGGATGGGGAAAGCATAACTGTGATCATGC TNGAGATGCTGNAGTGATTTGCTCAAGGGAGCAGATCTGAGCCTGAGACTGG >OriGene 3' read for NM_004244 unedited
GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAACATTCTTATTTATTTATTTAA TTCCCTTGAAAGTCTCATATACACCACTAAGTAGTCACATTCACAAACTTAATTTTTATA AATTCAGCAGCAGTCTTAGGAATCCTAGGAGAAGAAGAACTCCATAAAAATGCAACTGTA ATAGTCAGTGAGAGAGGTGAATTTCTGCTCCATTCAATAGTCCAGGTCTTCATCAAGGCA TCTTAAAGGCTGAACTCACTGGGTTATAAATTCCCATTTTGCTTTCGAGTGTGGCTCACA ATGGCCTTCTGAGGACTCCCTTATGCCCCCATCATGTGCCGTTCCGCTGGACTCCTTTTT CCGGCCTTGTATCTCCTGGTTTCCCCTTCCTCGCTCCGTCGCACCCCCCCCCCGATTACT GTACCCCCCCGCCCTTCATTCTTACACCTTGCTCATCTTCCGGTTTTCTCCCCTATCCAA CGCTTCCTCTTCCTTTACCCCCCCCCTTCTCTCCCCCTCTCTCTTCCTCCTCCTCCTCCT TCCCCTTTTCCCTTTTTTCCTCTCCCCTTTGCATTTTTTCTTTCTCCTCTCTCCTTCCCC GTTTTTTCCCCTTGACTTCCCCTTCCCTTTCTCTTTCCCCCCCTCGTCCGCCATTTTTTT TTCATCCCCTTCCTTTCCCCTCCTTTTCTCCTCTTTCCCCCCGTTCTCCTCCCCTCCCTC CACCCCTTTGTAGTTCTCCGCCGCCCCGCCCCTTTTCTCTCTTCCCCCACCCACCCTCTC CCCTTTCCGTTCCTTTCCCCCCTTTTGCCCCTTTCCCTCCCCCTCTTCCGCTATTCTTCT CTCTCCCTCCCACCTCTTCCTTCTCCCTCCCCCCGTTCCCCTCTCTTCCCTTCTTCTCTC TCCGCACGCTCTTTTACCGCCGTCCTCTTTGTCTTTTTTCCTTCTTCCCCCCCTTTCCTG TTCCCTTTCTCTCCCCTCGCCCTCCCCTCTTTATGCCATCTTCGCTCGTATTCCTTACTT TATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004244 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004244.3, NP_004235.3 |
| RefSeq Size | 3806 bp |
| RefSeq ORF | 3471 bp |
| Locus ID | 9332 |
| UniProt ID | Q86VB7 |
| Domains | SR |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (1), also known as long tail variant 1, represents the longer transcript and encodes the longer isoform (a). |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Cytokine production capabilities of human primary monocyte-derived macrophages from patients with diabetes mellitus type 2 with and without diabetic peripheral neuropathy
,Alvarado-Vázquez, PA;Grosick, RL;Moracho-Vilrriales, C;Ward, E;Threatt, T;Romero-Sandoval, EA;,
J Pain Res
,PubMed ID 30588081
[CD163]
|
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CD163 overexpression using a macrophage-directed gene therapy approach improves wound healing in ex vivo and in vivo human skin models
,Ferreira, DW;Ulecia-Morón, C;Alvarado-Vázquez, PA;Cunnane, K;Moracho-Vilriales, C;Grosick, RL;Cunha, TM;Romero-Sandoval, EA;,
Immunobiology
,PubMed ID 31711674
[CD163]
|
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The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation
,Yang, H;Wang, H;Wang, Y;Addorisio, M;Li, J;Postiglione, MJ;Chavan, SS;Al-Abed, Y;Antoine, DJ;Andersson, U;Tracey, KJ;,
J. Intern. Med.
,PubMed ID 28464519
[CD163]
|
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Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes
,Yang, H;Wang, H;Levine, YA;Gunasekaran, MK;,
JCI Insight
,PubMed ID 27294203
[CD163]
|
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A Previously Unrecognized Protein-Protein Interaction between TWEAK and CD163: Potential Biological Implications
,LC Bover, M Cardo-Vila, A Kuniyasu, J Sun, R Rangel, M Takeya, BB Aggarwal, W Arap, and R Pasqualini,
J Immunol. 2007 Jun 15;178(12):8183-94
[CD163]
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CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
,Dominik J. Schaer, Christian A. Schaer, Paul W. Buehler, Robert A. Boykins, Gabriele Schoedon, Abdu I. Alayash, and Andreas Schaffner,
Blood. 2006 Jan 1;107(1):373-80.
[CD163]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208557 | CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 1 |
CNY 8,048.00 |
|
| RC208557L1 | Lenti ORF clone of Human CD163 molecule (CD163), transcript variant 1, Myc-DDK-tagged |
CNY 10,448.00 |
|
| RC208557L2 | Lenti ORF clone of Human CD163 molecule (CD163), transcript variant 1, mGFP tagged |
CNY 13,400.00 |
|
| RC208557L3 | Lenti ORF clone of Human CD163 molecule (CD163), transcript variant 1, Myc-DDK-tagged |
CNY 10,448.00 |
|
| RC208557L4 | Lenti ORF clone of Human CD163 molecule (CD163), transcript variant 1, mGFP tagged |
CNY 10,448.00 |
|
| RG208557 | CD163 (tGFP-tagged) - Human CD163 molecule (CD163), transcript variant 1 |
CNY 9,648.00 |
