Ephrin B2 (EFNB2) (NM_004093) Human Untagged Clone
CAT#: SC117586
EFNB2 (untagged)-Human ephrin-B2 (EFNB2)
CNY 3,656.00
CNY 7,220.00
Cited in 4 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | EPLG5; Htk-L; HTKL; LERK5 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_004093, the custom clone sequence may differ by one or more nucleotides
ATGGCTGTGAGAAGGGACTCCGTGTGGAAGTACTGCTGGGGTGTTTTGATGGTTTTATGCAGAACTGCGA TTTCCAAATCGATAGTTTTAGAGCCTATCTATTGGAATTCCTCGAACTCCAAATTTCTACCTGGACAAGG ACTGGTACTATACCCACAGATAGGAGACAAATTGGATATTATTTGCCCCAAAGTGGACTCTAAAACTGTT GGCCAGTATGAATATTATAAAGTTTATATGGTTGATAAAGACCAAGCAGACAGATGCACTATTAAGAAGG AAAATACCCCTCTCCTCAACTGTGCCAAACCAGACCAAGATATCAAATTCACCATCAAGTTTCAAGAATT CAGCCCTAACCTCTGGGGTCTAGAATTTCAGAAGAACAAAGATTATTACATTATATCTACATCAAATGGG TCTTTGGAGGGCCTGGATAACCAGGAGGGAGGGGTGTGCCAGACAAGAGCCATGAAGATCCTCATGAAAG TTGGACAAGATGCAAGTTCTGCTGGATCAACCAGGAATAAAGATCCAACAAGACGTCCAGAACTAGAAGC TGGTACAAATGGAAGAAGTTCGACAACAAGTCCCTTTGTAAAACCAAATCCAGGTTCTAGCACAGACGGC AACAGCGCCGGACATTCGGGGAACAACATCCTCGGTTCCGAAGTGGCCTTATTTGCAGGGATTGCTTCAG GATGCATCATCTTCATCGTCATCATCATCACGCTGGTGGTCCTCTTGCTGAAGTACCGGAGGAGACACAG GAAGCACTCGCCGCAGCACACGACCACGCTGTCGCTCAGCACACTGGCCACACCCAAGCGCAGCGGCAAC AACAACGGCTCAGAGCCCAGTGACATTATCATCCCGCTAAGGACTGCGGACAGCGTCTTCTGCCCTCACT ACGAGAAGGTCAGCGGGGACTACGGGCACCCGGTGTACATCGTCCAGGAGATGCCCCCGCAGAGCCCGGC GAACATTTACTACAAGGTCTGA >OriGene 5' read for NM_004093 unedited
NGGTTGCCATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACCAGNAGGATTGG GGGTCCCAGCCTGCGTCCCGTCAGTCCCTTCTTGGCCCGGAGTGCGCGGAGCTGGGAGTG GCTTCGCCATGGCTGTGAGAAGGGACTCCGTGTGGAAGTACTGCTGGGGTGTTTTGATGG TTTTATGCAGAACTGCGATTTCCAAATCGATAGTTTTAGAGCCTATCTATTGGAATTCCT CGAACTCCAAATTTCTACCTGGACAAGGACTGGTACTATACCCACAGATAGGAGACAAAT TGGATATTATTTGCCCCAAAGTGGACTCTAAAACTGTTGGCCAGTATGAATATTATAAAG TTTATATGGTTGATAAAGACCAAGCAGACAGATGCACTATTAAGAAGGAAAATACCCCTC TCCTCAACTGTGCCAAACCAGACCAAGATATCAAATTCACCATCAAGTTTCAAGAATTCA GCCCTAACCTCTGGGGTCTAGAATTTCAGAAGAACAAAGATTATTACATTATATCTACAT CAAATGGGTCTTTGGAGGGCCTGGATACCAGGAGGGAGGGGTGTGCCAGACAAGAGCCAT GAAGATCCTCATGANAGTTGGACAAGATGCAAGTTCTGCTGNGATCAACCAGAATAAAGA TCCAACAAGACGTCCAGAACTAGAAGCTGGTACANATGGAAGAAGTTCGACACCCAGTCC CTTTGTANAACCAAATCCAGGTTCTAGCACAGACCGGCACAGCGCCCGACATTCGGNGAA ACACATCCNTCGTTCCGAAGTGGCCTTATTTGCAGGNATTGCTTCAGGATGCATCATCTT CATCGNCATCATCATCACGCTGGTGGGTCCTCTTGCTGAAGTCCCGNAGGAGACACAGGA AGCACTCGNCGCNACACACGACCACGCTGTCGCTCAGACACTGGCCACACCCAGCGCAAG >OriGene 3' read for NM_004093 unedited
NCCCGGCCTTGGGGAATATTTTCATTTTTTAAAAACAAATCATTTGAAACANAGTGGAAT GTGACTTCACGGATTTCATTTTCTGGGGCTAACTGCAATGTGAAACTAAAGCAGATTTAA AACCTATGACAGGCTATTAAAATAAAACAAAGAAAGAAAAAAATATTTATAACTCAGGCA TAATACTGTGTTACTTACAAATTGGACAACGAAATTTTAAATAAATATTCATGGTACATA ATTACGGCACAAATATGCAGCAATTTGGCAACCTTTTATACCATTTTTTCCTCATTACAG TGCAAAGGGGAATGACACTGCCGTTAAACAAGCTGTAGCTAAATACATTGCAAAATTCAG ATTTTATACAAAACATCTTGCTTAGACTTTATAAAAAACCAACATTGCTCTATGTACACA ATCTGGGTAAGAAAAGCCATTTCTTTCTTGTTTTCATGTGTATTTTTATTAAAAAGGTGA ATAAGGCTACTGTAACACCCCAAATCCATAGACAGTAAAATCTGAACCTATTTACAGCAT CTTCACTGAAACATGATGGTGCAAATTCCAAAGTCGGGTGACCAGNGACGATCATACAAG CAAGGCATTTACAGTAACTTTCCAAAGCTAAACCAACTTCAAACAAAGGGACAGTTGGTA GATTGTCATATTCTGCACCAGACACAAAACAGACGCACAGAACACTTTTCAATTGGTTGC AGGGAACTCTTTTATCAATTCATCTGATTTTTCACAGTTTAGCATAGAACCAAAACGTAG CCAACTGATGATACATACTTTTGATTTCATTAAAATCAGACTATTTCCCATTTTTTCCCT TTNTTGCCCTCTCCCCCAATCCTAAAATTACTTCTGATGGCTTAAAAGAAACTCTTGCTG GATTGCAC |
Restriction Sites | NotI-NotI |
ACCN | NM_004093 |
Insert Size | 4700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_004093.2, NP_004084.1 |
RefSeq Size | 4335 bp |
RefSeq ORF | 1002 bp |
Locus ID | 1948 |
UniProt ID | P52799 |
Domains | Ephrin |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Axon guidance |
Gene Summary | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008] |
Citations (4)
The use of this cDNA Clones has been cited in the following citations: |
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p75NTR-dependent activation of NF-[kappa] B regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia
,Caporali, A;Meloni, M;Nailor, A;Mitic, T;,
Nature Communications
,PubMed ID 26268439
[EFNB2]
|
Identification of residues in the Hendra virus G glycoprotein critical for receptor binding
,Kimberly A Bishop, Tzanko S Stantchev, Andrew C Hickey, Dimple Khetawat, Katharine N Bossart, Valery Krasnoperov, Parkash Gill, Yan-Ru Feng, Lemin Wang, Bryan T Eaton, Lin-Fa Wang, and Christopher C Broder,
J Virol. 2007 Jun;81(11):5893-901.
[EFNB2]
|
Evidence of a Potential Receptor-Binding Site on the Nipah Virus G Protein (NiV-G): Identification of Globular Head Residues with a Role in Fusion Promotion and Their Localization on an NiV-G Structural Model
,Vanessa Guillaume, Hamide Aslan, Michelle Ainouze, Mathilde Guerbois, T. Fabian Wild, Robin Buckland, and Johannes P. M. Langedijk,
J. Virol., Aug 2006; 80: 7546 - 7554.
[EFNB2]
|
Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus
,Matthew I. Bonaparte, Antony S. Dimitrov, Katharine N. Bossart, Gary Crameri, Bruce A. Mungall, Kimberly A. Bishop, Vidita Choudhry, Dimiter S. Dimitrov, Lin-Fa Wang, Bryan T. Eaton, and Christopher C. Broder,
Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10652-7.
[EFNB2]
|
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