CASK (NM_003688) Human Untagged Clone
CAT#: SC117810
CASK (untagged)-Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1
CNY 6,752.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CAGH39; CAMGUK; CMG; FGS4; hCASK; LIN2; MICPCH; MRXSNA; TNRC8 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_003688 edited
ATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAG GGTCCCTTCAGTGTTGTACGACGATGTATCAACAGAGAAACTGGGCAACAATTTGCTGTA AAAATTGTTGATGTAGCCAAGTTCACATCAAGTCCAGGGTTAAGTACAGAAGATCTAAAG CGGGAAGCCAGTATCTGTCATATGCTGAAACATCCACACATTGTAGAGTTATTGGAGACA TATAGCTCAGATGGAATGCTTTACATGGTTTTCGAATTTATGGATGGAGCAGATCTGTGT TTTGAAATCGTAAAGCGAGCTGACGCTGGTTTTGTGTACAGTGAAGCTGTAGCCAGCCAT TATATGAGACAGATACTGGAAGCTCTACGCTACTGCCATGATAATAACATAATTCACAGG GATGTGAAGCCCCACTGTGTTCTCCTTGCCTCAAAAGAAAACTCGGCACCTGTTAAACTT GGAGGCTTTGGGGTAGCTATTCAATTAGGGGAGTCTGGACTTGTAGCTGGAGGACGTGTT GGAACACCTCATTTTATGGCACCAGAAGTGGTCAAAAGAGAGCCTTACGGAAAGCCTGTA GACGTCTGGGGGTGCGGTGTGATCCTTTTTATCCTGCTCAGTGGTTGTTTGCCTTTTTAC GGAACCAAGGAAAGATTGTTTGAAGGCATTATTAAAGGAAAATATAAGATGAATCCAAGG CAGTGGAGCCATATCTCTGAAAGTGCCAAAGACCTAGTACGTCGCATGCTGATGCTGGAT CCAGCTGAAAGGATCACTGTTTATGAAGCACTGAATCACCCATGGCTTAAGGAGCGGGAT CGTTACGCCTACAAGATTCATCTTCCAGAAACAGTAGAGCAGCTGAGGAAATTCAATGCA AGGAGGAAACTAAAGGGTGCAGTACTAGCCGCTGTGTCAAGTCACAAATTCAACTCATTC TATGGGGATCCCCCTGAAGAGTTACCAGATTTCTCCGAAGACCCTACCTCCTCAGGAGCA GTCTCACAGGTGCTGGACAGCCTGGAAGAGATTCATGCGCTTACAGACTGCAGTGAAAAG GACCTAGATTTTCTACACAGTGTTTTCCAGGATCAGCATCTTCACACACTACTAGATCTG TATGACAAAATTAACACAAAGTCTTCACCACAAATCAGGAATCCTCCAAGCGATGCAGTA CAGAGAGCCAAAGAGGTATTGGAAGAAATTTCATGTTACCCTGAGAATAACGACGCAAAG GAACTAAAGCGTATTTTAACACAACCTCATTTCATGGCCTTACTTCAGACTCACGACGTA GTGGCACATGAAGTTTACAGTGATGAAGCATTGAGGGTCACACCTCCTCCCACCTCTCCC TATTTAAACGGCGATTCTCCAGAAAGTGCTAACGGAGACATGGATATGGAGAATGTGACC AGAGTTCGGCTGGTACAGTTTCAAAAGAACACAGATGAACCAATGGGAATCACTTTAAAA ATGAATGAACTAAATCATTGTATTGTTGCAAGAATTATGCATGGGGGCATGATTCACAGG CAAGGTACACTTCATGTTGGTGATGAAATTCGAGAAATCAATGGCATCAGTGTGGCTAAC CAAACAGTGGAACAACTGCAAAAAATGCTTAGGGAAATGCGGGGGAGTATTACCTTCAAG ATTGTGCCAAGTTACCGCACTCAGTCTTCGTCCTGTGAGGACTTGCCATCAACTACCCAA CCAAAAGGACGACAGATCTATGTAAGAGCACAATTTGAATATGATCCAGCCAAGGATGAC CTCATCCCCTGTAAAGAAGCTGGCATTCGATTCAGAGTTGGTGACATCATCCAGATTATT AGTAAGGATGATCATAATTGGTGGCAGGGTAAACTGGAAAACTCCAAAAATGGAACTGCA GGTCTCATTCCTTCTCCTGAACTTCAGGAATGGCGAGTAGCTTGCATTGCCATGGAGAAG ACCAAACAGGAGCAGCAGGCCAGCTGTACTTGGTTTGGCAAGAAAAAGAAGCAGTACAAA GATAAATATTTGGCAAAGCACAATGCAGTGTTTGATCAATTAGATCTTGTCACATATGAA GAAGTAGTAAAACTGCCAGCATTCAAGAGGAAAACACTAGTCTTATTAGGCGCACATGGT GTTGGGAGAAGACACATAAAAAACACTCTCATCACAAAGCACCCAGACCGGTTTGCGTAC CCTATTCCACATACAACCAGACCTCCAAAGAAAGACGAAGAAAATGGAAAGAATTATTAC TTTGTATCTCATGACCAAATGATGCAAGACATCTCTAATAACGAGTACTTGGAGTACGGC AGCCACGAGGATGCGATGTATGGGACAAAACTGGAGACCATCCGGAAGATCCACGAGCAG GGGCTGATTGCAATACTGGACGTGGAGCCTCAGGCACTGAAGGTCCTGAGAACTGCAGAG TTTGCTCCTTTTGTTGTTTTCATTGCTGCACCAACTATTACTCCAGGTTTAAATGAGGAT GAATCTCTTCAGCGTCTGCAGAAGGAGTCTGACATCTTACAGAGAACATATGCACACTAC TTCGATCTCACAATTATCAACAATGAAATTGATGAGACAATCAGACATCTGGAGGAAGCT GTTGAGCTCGTGTGCACAGCCCCACAGTGGGTCCCTGTCTCCTGGGTCTATTAGGCCTCT CCCCAGATATCTGAGCATAACTGGGAGCACCTCATTTGTGGAAAAGCCTCTTTGTTATCG GCCTTGTGTCAGCAGGTCATGGTCCCTAGAGACTACCTAGTTGTAGTGTGACCTACATTT ATAATTATTGTCATGTCCGAATAGATAGGAGGAGAAAAACAATTACACACTAATTTAAAG AGACAGTATCTTTTTTAATCAGTTCTCCTAAACTTTAATAAAATGTATCTTTAAATGTAT GTATTATTCAATCCTTTGGAATGTTATATTTTTGGAAATCATAGCTTTTTATTTCCAAGG CCCCTAAAAACTGCACAAAATAGATGCTGCTTTCTATAATCTATTTTAATAATAATAAAC AATGATTCTGTTACCTTGAAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGC GGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCC TCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTG >OriGene 5' read for NM_003688 unedited
ATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGTTTTCGAAGCCCTCCAC GCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGT ACGAGCTGTGCGAGGTGATCGGAAAGGGTCCCTTCAGTGTTGTACGACGATGTATCAACA GAGAAACTGGGCAACAATTTGCTGTAAAAATTGTTGATGTAGCCAAGTTCACATCAAGTC CAGGGTTAAGTACAGAAGATCTAAAGCGGGAAGCCAGTATCTGTCATATGCTGAAACATC CACACATTGTAGAGTTATTGGAGACATATAGCTCAGATGGAATGCTTTACATGGTTTTCG AATTTATGGATGGAGCAGATCTGTGTTTTGAAATCGTAAAGCGAGCTGACGCTGGTTTTG TGTACAGTGAAGCTGTAGCCAGCCATTATATGAGACAGATACTGGAAGCTCTACGCTACT GCCATGATAATAACATAATTCACAGGGATGTGAAGCCCCACTGTGTTCTCCTTGCCTCAA AAGAAAACTCGGCACCTGTTAAACTTGGAGGCTTTGGGGTAGCTATTCAATTAGGGGAGT CTGGACTTGTAGCTGGAGGACGTGTTGGAACACCTCATTNTATGGCACCAGAAGTGGTCA AAAGAGAGCCTTACGGAAAGCCTGTANACGTCTGGGGGTGCGGTGTGATCCTTTNTATCC TGCTCAGTGGGNTGTTGCCTTTNTACNGNNACCAAGNAAGATTTGTTGAAGGCTTATTAA AGGGAAATATTAGATGAATCCCAGGCAGTGGAGCCATATCTCTGAAAGTGCCAAGACCTA NTACGTCGCATGCTGATGCTGGATCCANCTGAAGGATCACTGTNTATGAAGCCTGAATCA CCATGGCTTAGGAGCGGNNATCGTACGCTACAGATCATCTTCAGAACAC >OriGene 3' read for NM_003688 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTCAAGGAAACAGAATCA TTGTTTATTATTATTAAAATAGATTATAGAAAGCAGCATCTATTTTGTGCAGTTTTTAGG GGCCTTGGAAATAAAAAGCTATGATTTCCAAAAATATAACATTCCAAAGGATTGAATAAT ACATACATTTAAAGATACATTTTATTAAAGTTTAGGAGAACTGATTAAAAAAGATACTGT CTCTTTAAATTAGGGTGTAATTGTTTTTCTCCTCCTATCTATTCGGACATGACAATAATT ATAAATGTAGGTCACACTACAACTAGGTAGTCTCTAGGGACCATGACCTGCTGACACAAG GCCGATAACAAAGAGGCTTTTCCACAAATGAGGTGCTCCCAGTTATGCTCAGATATCTGG GGAGAGGCCTAATAGACCCAGGAGACAGGGACCCACTGTGGGGCTGTGCACACGAGCTCA ACAGCTTCCTCCAGATGTCTGATTGTCTCATCAATTTCATTGTTGATAATTGGGAGATCG AAGTAGTGTGCATATGTTCTCTGTAAGATGTCAGACTCCTTCTGCAGACGCTGAAGAGAT TCATCCTCATTTAAACCTGNAGTAATAGTTGGTGCCACAATGAAAACAACAAAAGGACCA AACTCTGCAATTCTCAAGACCTTTAGTGCCTGAAGCTCCACGTCCAGTATTGCAATCAGC CCCTGCTCGTGGATCTTCCGGATGGTCTCCAGTTTTGTCCCATACATGCATCCCTGTGGT TGCCGTACTCCAAGACTTCGTATAAGAAATGCCTTGCATCATTTGGCCATGAGAAACAAA GAATAATTCCTCTCCTTTTCTTCCCTTTTTTCTGAGTCCGGGTTGATGGGAAAAAGGCAC CCAAACCGGTCGGGTGCCTTGGGAAAAAAAGGTTTTAATTGGCTTTTCCAAACCCTGGGC N |
Restriction Sites | NotI-NotI |
ACCN | NM_003688 |
Insert Size | 3490 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_003688.1, NP_003679.1 |
RefSeq Size | 3122 bp |
RefSeq ORF | 2766 bp |
Locus ID | 8573 |
UniProt ID | O14936 |
Domains | pkinase, TyrKc, SH3, PDZ, S_TKc, L27, Guanylate_kin, GuKc |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Tight junction |
Gene Summary | This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
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SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC220531 | CASK (Myc-DDK-tagged)-Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1 |
CNY 6,784.00 |
|
RC220531L1 | Lenti-ORF clone of CASK (Myc-DDK-tagged)-Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1 |
CNY 9,184.00 |
|
RC220531L2 | Lenti-ORF clone of CASK (mGFP-tagged)-Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1 |
CNY 11,590.00 |
|
RC220531L3 | Lenti-ORF clone of CASK (Myc-DDK-tagged)-Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1 |
CNY 11,590.00 |
|
RC220531L4 | Lenti-ORF clone of CASK (mGFP-tagged)-Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1 |
CNY 11,590.00 |
|
RG220531 | CASK (tGFP-tagged) - Human calcium/calmodulin-dependent serine protein kinase (MAGUK family) (CASK), transcript variant 1 |
CNY 8,384.00 |