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VRK1 (NM_003384) Human Untagged Clone
CAT＃: SC117994
VRK1 (untagged)-Human vaccinia related kinase 1 (VRK1)
CNY 3,656.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PCH1; PCH1A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_003384 edited
ATGCCTCGTGTAAAAGCAGCTCAAGCTGGAAGACAGAGCTCTGCAAAGAGACATCTTGCA GAACAATTTGCAGTTGGAGAGATAATAACTGACATGGCAAAAAAGGAATGGAAAGTAGGA TTACCCATTGGCCAAGGAGGCTTTGGCTGTATATATCTTGCTGATATGAATTCTTCAGAG TCAGTTGGCAGTGATGCACCTTGTGTTGTAAAAGTGGAACCCAGTGACAATGGACCTCTT TTTACTGAATTAAAGTTCTACCAACGAGCTGCAAAACCAGAGCAAATTCAGAAATGGATT CGTACCCGTAAGCTGAAGTACCTGGGTGTTCCTAAGTATTGGGGGTCTGGTCTACATGAC AAAAATGGAAAAAGTTACAGGTTTATGATAATGGATCGCTTTGGGAGTGACCTTCAGAAA ATATATGAAGCAAATGCCAAAAGGTTTTCTCGGAAAACTGTCTTGCAGCTAAGCTTAAGA ATTCTGGATATTCTGGAATATATTCACGAGCATGAGTATGTGCATGGAGATATCAAGGCC TCAAATCTTCTTCTGAACTACAAGAATCCTGACCAGGTGTACTTGGTAGATTATGGCCTT GCTTATCGGTACTGCCCAGAAGGAGTTCATAAAGAATACAAAGAAGACCCCAAAAGATGT CACGATGGCACTATTGAATTCACGAGCATCGATGCACACAATGGCGTGGCCCCATCAAGA CGTGGTGATTTGGAAATACTTGGTTATTGCATGATCCAATGGCTTACTGGCCATCTTCCT TGGGAGGATAATTTGAAAGATCCTAAATATGTTAGAGATTCCAAAATTAGATACAGAGAA AATATTGCAAGTTTGATGGACAAATGTTTTCCTGAGAAAAACAAACCAGGTGAAATTGCC AAATACATGGAAACAGTGAAATTACTAGACTACACTGAAAAACCTCTTTATGAAAATTTA CGTGACATTCTTTTGCAAGGACTAAAAGCTATAGGAAGTAAGGATGATGGCAAATTGGAC CTCAGTGTTGTGGAGAATGGAGGTTTGAAAGCAAAAACAATAACAAAGAAGCGAAAGAAA GAAATTGAAGAAAGCAAGGAACCTGGTGTTGAAGATACGGAATGGTCAAACACACAGACA GAGGAGGCCATACAGACCCGTTCAAGAACCAGAAAGAGAGTCCAGAAGTAA >OriGene 5' read for NM_003384 unedited
GTAATACGACTCACTATAGGGCGGCCGCNGAATTCGCACGAGGCGGGAAGTTCGTACTGG GCAGAACGCGACGGGTCTGCGGCTTAGGTGAAAATGCCTCGTGTAAAAGCAGCTCAAGCT GGAAGACAGAGCTCTGCAAAGAGACATCTTGCAGAACAATTTGCAGTTGGAGAGATAATA ACTGACATGGCAAAAAAGGAATGGAAAGTAGGATTACCCATTGGCCAAGGAGGCTTTGGC TGTATATATCTTGCTGATATGAATTCTTCAGAGTCAGTTGGCAGTGATGCACCTTGTGTT GTAAAAGTGGAACCCAGTGACAATGGACCTCTTTTTACTGAATTAAAGTTCTACCAACGA GCTGCAAAACCAGAGCAAATTCAGAAATGGATTCGTACCCGTAAGCTGAAGTACCTGGGT GTTCCTAAGTATTGGGGGTCTGGTCTACATGACAAAAATGGAAAAAGTTACAGGTTTATG ATAATGGATCGCTTTGGGAGTGACCTTCAGAAAATATATGAAGCAAATGCCAAAAGGTTT TCTCGGAAAACTGTCTTGCAGCTAAGCTTAAGAATTCTGGATATTCTGGAATATATTCAC GAGCATGAGTATGTGCATGGAGATATCAAGGCCTCAAATCTTCTTCTGAACTACAAGAAT CCTGACCAGGTGTACTTGGTAGATTATGGCCTTGCTTATCGGTACTGCCCAGAAGGAGTT CATAAAGAATACANAGAAGACCCCANAGATGTCACGATGGCACTATTGAATTCACGAGCA TCGATGCACACAATGGCGTGGCCCCATCAAGACGTGGGTGATTGGAAATACTTGGNTATT GCATGATCCAATGGCTTACTGGCCATCTTTCTTGGNGAGATNNATTGAAAAGATCCTAAT ATGTTAGAGATTCCAAATTAGATACAGAAATATATTGCAGNTTGATGGACAATGTTTNCT G >OriGene 3' read for NM_003384 unedited
TGCTACAACAAAAGAGATGTATTTTAAGCTTTGCATTTCCTTAAAGTGAGGACTTTGTCA AACATTTTTATCCACTCTGAGAAAGTACAATGATTAGAAAAGTGCGTGTCATAATAATTT TCATATATATGTACTCCAAAACATCACAAACACACGGCTTTGGGATAACTTAAGGAGTAT AACCTGAAGATTTTCAAATTTCATAAATTAGCCTTTAATGAATTGTACAAAATATTTTTA TAAAAAAAGTTTATGTTTTCTGAACACATGAGTATTTAATCATTACTTCCACCTCGCAAG ACTCACAGGAAAATAAAACAGTTCAAATAGAAAAGGAGAAAAAAGTCAAAAGAAAACAAA GAAAAGGAAATCTGGTTCACAGCATCTGAATTACTTCTGGACTCTCTTTCTGGTTCTTGA ACGGGTCTGTATGGCCTCCTCTGTCTGTGTGTTTGACCATTCCGTATCTTCAACACCAGG TTCCTTGCTTTCTTCAATTTCTTTCTTTCGCTTCTTTGTTATTGTTTTTGCTTTCAAACC TTCATTCTCCACAACACTGAGGTCCAATTTGCCATCATCCTTACTTCCTATAGCTTTTAG TCCTTTGCAAAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003384 |
| Insert Size | 1630 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003384.2, NP_003375.1 |
| RefSeq Size | 1720 bp |
| RefSeq ORF | 1191 bp |
| Locus ID | 7443 |
| UniProt ID | Q99986 |
| Domains | pkinase, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210764 | VRK1 (Myc-DDK-tagged)-Human vaccinia related kinase 1 (VRK1) |
CNY 3,656.00 |
|
| RC210764L1 | Lenti ORF clone of Human vaccinia related kinase 1 (VRK1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210764L2 | Lenti ORF clone of Human vaccinia related kinase 1 (VRK1), mGFP tagged |
CNY 5,890.00 |
|
| RC210764L3 | Lenti ORF clone of Human vaccinia related kinase 1 (VRK1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210764L4 | Lenti ORF clone of Human vaccinia related kinase 1 (VRK1), mGFP tagged |
CNY 5,890.00 |
|
| RG210764 | VRK1 (tGFP-tagged) - Human vaccinia related kinase 1 (VRK1) |
CNY 5,256.00 |
|
| SC323490 | VRK1 (untagged)-Kinase deficient mutant (K71M) of Human vaccinia related kinase 1 (VRK1) |
CNY 3,656.00 |
