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CD45 (PTPRC) (NM_002838) Human Untagged Clone
CAT＃: SC118363
PTPRC (untagged)-Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1
CNY 9,088.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002838 edited
GGCCGCGAATTCGGCACGAGGCAGCTAGCAAGTGGTTTGTTCTTAGGGTAACAGAGGAGG AAATTGTTCCTCGTCTGATAAGACAACAGTGGAGAAAGGACGCATGCTGTTTCTTAGGGA CACGGCTGACTTCCAGATATGACCATGTATTTGTGGCTTAAACTCTTGGCATTTGGCTTT GCCTTTCTGGACACAGAAGTATTTGTGACAGGGCAAAGCCCAACACCTTCCCCCACTGGA TTGACTACAGCAAAGATGCCCAGTGTTCCACTTTCAAGTGACCCCTTACCTACTCACACC ACTGCATTCTCACCCGCAAGCACCTTTGAAAGAGAAAATGACTTCTCAGAGACCACAACT TCTCTTAGTCCAGACAATACTTCCACCCAAGTATCCCCGGACTCTTTGGATAATGCTAGT GCTTTTAATACCACAGGTGTTTCATCAGTACAGACGCCTCACCTTCCCACGCACGCAGAC TCGCAGACGCCCTCTGCTGGAACTGACACGCAGACATTCAGCGGCTCCGCCGCCAATGCA AAACTCAACCCTACCCCAGGCAGCAATGCTATCTCAGATGTCCCAGGAGAGAGGAGTACA GCCAGCACCTTTCCTACAGACCCAGTTTCCCCATTGACAACCACCCTCAGCCTTGCACAC CACAGCTCTGCTGCCTTACCTGCACGCACCTCCAACACCACCATCACAGCGAACACCTCA GATGCCTACCTTAATGCCTCTGAAACAACCACTCTGAGCCCTTCTGGAAGCGCTGTCATT TCAACCACAACAATAGCTACTACTCCATCTAAGCCAACATGTGATGAAAAATATGCAAAC ATCACTGTGGATTACTTATATAACAAGGAAACTAAATTATTTACAGCAAAGCTAAATGTT AATGAGAATGTGGAATGTGGAAACAATACTTGCACAAACAATGAGGTGCATAACCTTACA GAATGTAAAAATGCGTCTGTTTCCATATCTCATAATTCATGTACTGCTCCTGATAAGACA TTAATATTAGATGTGCCACCAGGGGTTGAAAAGTTTCAGTTACATGATTGTACACAAGTT GAAAAAGCAGATACTACTATTTGTTTAAAATGGAAAAATATTGAAACCTTTACTTGTGAT ACACAGAATATTACCTACAGATTTCAGTGTGGTAATATGATATTTGATAATAAAGAAATT AAATTAGAAAACCTTGAACCCGAACATGAGTATAAGTGTGACTCAGAAATACTCTATAAT AACCACAAGTTTACTAACGCAAGTAAAATTATTAAAACAGATTTTGGGAGTCCAGGAGAG CCTCAGATTATTTTTTGTAGAAGTGAAGCTGCACATCAAGGAGTAATTACCTGGAATCCC CCTCAAAGATCATTTCATAATTTTACCCTCTGTTATATAAAAGAGACAGAAAAAGATTGC CTCAATCTGGATAAAAACCTGATCAAATATGATTTGCAAAATTTAAAACCTTATACGAAA TATGTTTTATCATTACATGCCTACATCATTGCAAAAGTGCAACGTAATGGAAGTGCTGCA ATGTGTCATTTCACAACTAAAAGTGCTCCTCCAAGCCAGGTCTGGAACATGACTGTCTCC ATGACATCAGATAATAGTATGCATGTCAAGTGTAGGCCTCCCAGGGACCGTAATGGCCCC CATGAACGTTACCATTTGGAAGTTGAAGCTGGAAATACTCTGGTTAGAAATGAGTCGCAT AAGAATTGCGATTTCCGTGTAAAAGATCTTCAATATTCAACAGACTACACTTTTAAGGCC TATTTTCACAATGGAGACTATCCTGGAGAACCCTTTATTTTACATCATTCAACATCTTAT AATTCTAAGGCACTGATAGCATTTCTGGCATTTCTGATTATTGTGACATCAATAGCCCTG CTTGTTGTTCTCTACAAAATCTATGATCTACATAAGAAAAGATCCTGCAATTTAGATGAA CAGCAGGAGCTTGTTGAAAGGGATGATGAAAAACAACTGATGAATGTGGAGCCAATCCAT GCAGATATTTTGTTGGAAACTTATAAGAGGAAGATTGCTGATGAAGGAAGACTTTTTCTG GCTGAATTTCAGAGCATCCCGCGGGTGTTCAGCAAGTTTCCTATAAAGGAAGCTCGAAAG CCCTTTAACCAGAATAAAAACCGTTATGTTGACATTCTTCCTTATGATTATAACCGTGTT GAACTCTCTGAGATAAACGGAGATGCAGGGTCAAACTACATAAATGCCAGCTATATTGAT GGTTTCAAAGAACCCAGGAAATACATTGCTGCACAAGGTCCCAGGGATGAAACTGTTGAT GATTTCTGGAGGATGATTTGGGAACAGAAAGCCACAGTTATTGTCATGGTCACTCGATGT GAAGAAGGAAACAGGAACAAGTGTGCAGAATACTGGCCGTCAATGGAAGAGGGCACTCGG GCTTTTGGAGATGTTGTTGTAAAGATCAACCAGCACAAAAGATGTCCAGATTACATCATT CAGAAATTGAACATTGTAAATAAAAAAGAAAAAGCAACTGGAAGAGAGGTGACTCACATT CAGTTCACCAGCTGGCCAGACCACGGGGTGCCTGAGGATCCTCACTTGCTCCTCAAACTG AGAAGGAGAGTGAATGCCTTCAGCAATTTCTTCAGTGGTCCCATTGTGGTGCACTGCAGT GCTGGTGTTGGGCGCACAGGAACCTATATCGGAATTGATGCCATGCTAGAAGGCCTGGAA GCCGAGAACAAAGTGGATGTTTATGGTTATGTTGTCAAGCTAAGGCGACAGAGATGCCTG ATGGTTCAAGTAGAGGCCCAGTACATCTTGATCCATCAGGCTTTGGTGGAATACAATCAG TTTGGAGAAACAGAAGTGAATTTGTCTGAATTACATCCATATCTACATAACATGAAGAAA AGGGATCCACCCAGTGAGCCGTCTCCACTAGAGGCTGAATTCCAGAGACTTCCTTCATAT AGGAGCTGGAGGACACAGCACATTGGAAATCAAGAAGAAAATAAAAGTAAAAACAGGAAT TCTAATGTCATCCCATATGACTATAACAGAGTGCCACTTAAACATGAGCTGGAAATGAGT AAAGAGAGTGAGCATGATTCAGATGAATCCTCTGATGATGACAGTGATTCAGAGGAACCA AGCAAATACATCAATGCATCTTTTATAATGAGCTACTGGAAACCTGAAGTGATGATTGCT GCTCAGGGACCACTGAAGGAGACCATTGGTGACTTTTGGCAGATGATCTTCCAAAGAAAA GTCAAAGTTATTGTTATGCTGACAGAACTGAAACATGGAGACCAGGAAATCTGTGCTCAG TACTGGGGAGAAGGAAAGCAAACATATGGAGATATTGAAGTTGACCTGAAAGACACAGAC AAATCTTCAACTTATACCCTTCGTGTCTTTGAACTGAGACATTCCAAGAGGAAAGACTCT CGAACTGTGTACCAGTACCAATATACAAACTGGAGTGTGGAGCAGCTTCCTGCAGAACCC AAGGAATTAATCTCTATGATTCAGGTCGTCAAACAAAAACTTCCCCAGAAGAATTCCTCT GAAGGGAACAAGCATCACAAGAGTACACCTCTACTCATTCACTGCAGGGATGGATCTCAG CAAACGGGAATATTTTGTGCTTTGTTAAATCTCTTAGAAAGTGCGGAAACAGAAGAGGTA GTGGATATTTTTCAAGTGGTAAAAGCTCTACGCAAAGCTAGGCCAGGCATGGTTTCCACA TTCGAGCAATATCAATTCCTATATGACGTCATTGCCAGCACCTACCCTGCTCAGAATGGA CAAGTAAAGAAAAACAACCATCAAGAAGATAAAATTGAATTTGATAATGAAGTGGACAAA GTAAAGCAGGATGCTAATTGTGTTAATCCACTTGGTGCCCCAGAAAAGCTCCCTGAAGCA AAGGAACAGGCTGAAGGTTCTGAACCCACGAGTGGCACTGAGGGGCCAGAACATTCTGTC AATGGTCCTGCAAGTCCAGCTTTAAATCAAGGTTCATAGGAAAAGACATAAATGAGGAAA CTCCAAACCTCCTGTTAGCTGTTATTTCTATTTTTGTAGAAGTAGGAAGTGAAAATAGGT ATACAGTGGATTAATTAAATGCAGCGAACCAATATTTGTAGAAGGGTTATATTTTACTAC TGTGGAAAAATATTTAAGATAGTTTTGCCAGAACAGTTTGTACAGACGTATGCTTATTTT AAAATTTTATCTCTTATTCAGTAAAAAACAACTTCTTTGTAATCGTTATGTGTGTATATG TATGTGTGTATGGGTGTGTGTTTGTGTGAGAGACAGAGAAAGAGAGAGAATTCTTTCAAG TGAATCTAAAAGCTTTTGCTTTTCCTTTGTTTTTATGAAGAAAAAATACATTTTATATTA GAAGTGTTAACTTAGCTTGAAGGATCTGTTTTTAAAAATCATAAACTGTGTGCAGACTCA ATAAAATCATGTACATTTTTGAAATGACCTCAAGATGTCCTCCTTGTTCTACTCATATAT ATCTATCTTATATAGTTTACTATTTTACTTCTAGAGATAGTACATAAAGGTGGTATGTGT GTGTATGCTACTACAAAAAAGTTGTTAACTAAATTAACATTGGGAAATCTTATATTCCAT ATATTAGCATTTAGTCCAATGTCTTTTTAAGCTTATTTAATTAAAAAATTTCCAGTGAGC TTATCATGCTGTCTTTACATGGGGTTTTCAATTAAATAAGCTCAAAAAAAAAAAAAAAAA AAAAAAAAAC >OriGene 5' read for NM_002838 unedited
GGTCCGCCATTTATGTATACGACTTCACTATAGGGCGGCCGCGAATCGGCACGAGGCAGC TAGCAAGTGGTTTGTTCTTAGGGTAACAGAGGAGGAAATTGTTCCTCGTCTGATAAGACA ACAGTGGAGAAAGGACGCATGCTGTTTCTTAGGGACACGGCTGACTTCCAGATATGACCA TGTATTTGTGGCTTAAACTCTTGGCATTTGGCTTTGCCTTTCTGGACACAGAAGTATTTG TGACAGGGCAAAGCCCAACACCTTCCCCCACTGGATTGACTACAGCAAAGATGCCCAGTG TTCCACTTTCAAGTGACCCCTTACCTACTCACACCACTGCATTCTCACCCGCAAGCACCT TTGAAAGAGAAAATGACTTCTCAGAGACCACAACTTCTCTTAGTCCAGACAATACTTCCA CCCAAGTATCCCCGGACTCTTTGGATAATGCTAGTGCTTTTAATACCACAGGTGTTTCAT CAGTACAGACGCCTCACCTTCCCACGCACGCAGACTCGCAGACGCCCTCTGCTGGAACTG ACACGCAGACATTCAGCGGCTCCGCCGCCAATGCAAAACTCAACCCTACCCCAGGCAGCA ATGCTATCTCAGATGTCCCAGGAGAGAGGAGTACAGCCAGCACCTTTCCTACAGACCCAG TTTCCCCATTGACAACCACCCTCAGCCTTGCACACCACAGCTCTGCTGCCTTACCTGCAC GCACCCTCCACACCACCATCACAGCGAACACCTCAGATGCCTACCTTAATGCCCTCTGAA CACCACTCTGAGCCCTTCTGGAAGCGCTGTCATTTCACCCACACATAGCTACTACTCCAT CTAAGCCACATGTGATGAANATATGCCAACTCACTGTGGATACTTATTAACACGAAACTA ATNTTTACAGCAAGCTAATGTTATGAGATGTGGATGTGGAACATT >OriGene 3' read for NM_002838 unedited
ATCTGNACCCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTGAGCT TATTTAATTGAAAACCCCATGTAAAGACAGCATGATAAGCTCACTGGAAATTTTTTAATT AAATAAGCTTAAAAAGACATTGGACTAAATGCTAATATATGGAATATAAGATTTCCCAAT GTTAATTTAGTTAACAACTTTTTTGTAGTAGCATACACACACATACCACCTTTATGTACT ATCTCTAGAAGTAAAATAGTAAACTATATAAGATAGATATATATGAGTAGAACAAGGAGG ACATCTTGAGGTCATTTCAAAAATGTACATGATTTTATTGAGTCTGCACACAGTTTATGA TTTTTAAAAACAGATCCTTCAAGCTAAGTTAACACTTCTAATATAAAATGTATTTTTTCT TCATAAAAACAAAGGAAAAGCAAAAGCTTTTAGATTCACTTGAAAGAATTCTCTCTCTTT CTCTGGCTCTCACACAAACACACACCCATACACACATACATATACACACATAACGATTAC AAAGAAGTTGTTTTTTACTGAATAAGAGATAAAATTTTAAAATAAGCATACGTCTGTACA AACTGTTCTGGCAAAACTATCCTAAATATTTTTTCCCAGTAGTAAAATATAACCCTTCTT ACAAATTGGGTTCGCTGGATTTAAATTAATCCACTGGATACCCTATTTTCACTTCCTACT TCTACCAAAAATAAAAATAACAGCTAACAGGAGGGTTGGGAAGTCCCCCATTAAGGCCTT TCCCTAGAACCTTGATTTAAAGCTGGACTTGCAGGAACATTGACAGAATGTTCTGGCCCC CTCAGGCCCCTCGGGGGTTAAGAACCTTAAACCTGGTTCCTTTGTTTTAAGGGACCTTTT TCGTGGGCACCCAGTGGGTTTAACCCATTTAACTCACCTGCCTTCCTACTGGCACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002838 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002838.2, NP_002829.2 |
| RefSeq Size | 5026 bp |
| RefSeq ORF | 3915 bp |
| Locus ID | 5788 |
| UniProt ID | P08575 |
| Domains | Y_phosphatase, PTPc_motif, FN3 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216590 | PTPRC (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1 |
CNY 9,096.00 |
|
| RC216590L1 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1, Myc-DDK-tagged |
CNY 11,496.00 |
|
| RC216590L2 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1, mGFP tagged |
CNY 14,920.00 |
|
| RC216590L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1, Myc-DDK-tagged |
CNY 11,496.00 |
|
| RC216590L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1, mGFP tagged |
CNY 11,496.00 |
|
| RG216590 | PTPRC (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1 |
CNY 10,696.00 |
