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MYD88 (NM_002468) Human Untagged Clone
CAT＃: SC118606
MYD88 (untagged)-Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2
CNY 3,600.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMD68; MYD88D |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002468 edited
GAATTCGGCACGAGGCGCGCTGAGGCTCCAGGACCGCCCGCCATGGCTGCAGGAGGTCCC GGCGCGGGGTCTGCGGCCCCGGTCTCCTCCACATCCTCCCTTCCCCTGGCTGCTCTCAAC ATGCGAGTGCGGCGCCGCCTGTCTCTGTTCTTGAACGTGCGGACACAGGTGGCGGCCGAC TGGACCGCGCTGGCGGAGGAGATGGACTTTGAGTACTTGGAGATCCGGCAACTGGAGACA CAAGCGGACCCCACTGGCAGGCTGCTGGACGCCTGGCAGGGACGCCCTGGCGCCTCTGTA GGCCGACTGCTCGAGCTGCTTACCAAGCTGGGCCGCGACGACGTGCTGCTGGAGCTGGGA CCCAGCATTGAGGAGGATTGCCAAAAGTATATCTTGAAGCAGCAGCAGGAGGAGGCTGAG AAGCCTTTACAGGTGGCCGCTGTAGACAGCAGTGTCCCACGGACAGCAGAGCTGGCGGGC ATCACCACACTTGATGACCCCCTGGGGCATATGCCTGAGCGTTTCGATGCCTTCATCTGC TATTGCCCCAGCGACATCCAGTTTGTGCAGGAGATGATCCGGCAACTGGAACAGACAAAC TATCGACTGAAGTTGTGTGTGTCTGACCGCGATGTCCTGCCTGGCACCTGTGTCTGGTCT ATTGCTAGTGAGCTCATCGAAAAGAGGTGCCGCCGGATGGTGGTGGTTGTCTCTGATGAT TACCTGCAGAGCAAGGAATGTGACTTCCAGACCAAATTTGCACTCAGCCTCTCTCCAGGT GCCCATCAGAAGCGACTGATCCCCATCAAGTACAAGGCAATGAAGAAAGAGTTCCCCAGC ATCCTGAGGTTCATCACTGTCTGCGACTACACCAACCCCTGCACCAAATCTTGGTTCTGG ACTCGCCTTGCCAAGGCCTTGTCCCTGCCCTGAAGACTGTTCTGAGGCCCTGGGTGTGTG TGTATCTGTCTGCCTGTCCATGTACTTCTGCCCTGCCTCCTCCTTTCGTTGTAGGAGGAA TCTGTGCTCTACTTACCTCTCAATTCCTGGAGATGCCAACTTCACAGACACGTCTGCAGC AGCTGGACATCACATTTCATGTCCTGCATGGAACCAGTGGCTGTGAGTGGCATGTCCACT TGCTGGATTATCAGCCAGGACACTATAGAACAGGACCAGCTGAGACTAAGAAGGACCAGC AGAGCCAGCTCAGCTCTGAGCCATTCACACATCTTCACCCTCAGTTTCCTCACTTGAGGA GTGGGATGGGGAGAACAGAGAGTAGCTGTGTTTGAATCCCTGTAGGAAATGGTGAAGCAT AGCTCTGGGTCTCCTGGGGGAGACCAGGCTTGGCTGCGGGAGAGCTGGCTGTTGCTGGAC TACATGCTGGCCACTGCTGTGACCACGACACTGCTGGGGCAGCTTCTTCCACAGTGATGC CTACTGATGCTTCAGTGCCTCTGCACACCGCCCATTCCACTTCCTCCTTCCCCACAGGGC AGGTGGGGAAGCAGTTTGGCCCAGCCCAAGGAGACCCCACCTTGAGCCTTATTTCCTAAT GGGTCCACCTCTCATCTGCATCTTTCACACCTCCCAGCTTCTGCCCAACCTTCAGCAGTG ACAAGTCCCCAAGAGACTCGCCTGAGCAGCTTGGGCTGCTTTTCATTTCCACCTGTCAGG ATGCCTGTGGTCATGCTCTCAGCTCCACCTGGCATGAGAAGGGATCCTGGCCTCTGGCAT ATTCATCAAGTATGAGTTCTGGGGATGAGTCACTGTAATGATGTGAGCAGGGAGCCTTCC TCCCTGGGCCACCTGCAGAGAGCTTTCCCACCAACTTTGTACCTTGATTGCCTTACAAAG TTATTTGTTTACAAACAGCGACCATATAAAAGCCTCCTGCCCCAAAGCTTGTGGGCACAT GGGCACATACAGACTCACATACAGACACACACATATATGTACAGACATGTACTCTCACAC ACACAGGCACCAGCATACACACGTTTTTCTAGGTACAGCTCCCAGGAACAGCTAGGTGGG AAAGTCCCATCACTGAGGGAGCCTAACCATGTCCCTGAACAAAAATTGGGCACTCATCTA TTCCTTTTCTCTTGTGTCCCTACTCATTGAAACCAAACTCTGGAAAGGACCCAATGTACC AGTATTTATACCTCTAGTGAAGCACAGAGAGAGGAAGAGAGCTGCTTAAACTCACACAAC AATGAACTGCAGACACAGCTGTTCTCTCCCTCTCTCCTTCCCAGAGCAATTTATACTTTA CCCTCAGGCTGTCCTCTGGGGAGAAGGTGCCATGGTCTTAGGTGTCTGTGCCCCAGGACA GACCCTAGGACCCTAAATCCAATAGAAAATGCATATCTTTGCTCCACTTTCAGCCAGGCT GGAGCAAGGTACCTTTTCTTAGGATCTTGGGAGGGAATGGATGCCCCTCTCTGCATGATC TTGTTGAGGCATTTAGCTGCCATGCACCTGTCCCCCTTTAATACTGGGCATTTTAAAGCC ATCTCAAGAGGCATCTTCTACATGTTTTGTACGCATTAAAATAATTTCAAAGATATCTGA GAAAAGCCGATATTTGCCATTCTTCCTATATCCTGGAATATATCTTGCATCCTGAGTTTA TAATAATAAATAATATTCTACCTTGGAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_002468 unedited
AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGCGCTGAGGCT CCAGGACCGCCCGCCATGGCTGCAGGAGGTCCCGGCGCGGGGTCTGCGGCCCCGGTCTCC TCCACATCCTCCCTTCCCCTGGCTGCTCTCAACATGCGAGTGCGGCGCCGCCTGTCTCTG TTCTTGAACGTGCGGACACAGGTGGCGGCCGACTGGACCGCGCTGGCGGAGGAGATGGAC TTTGAGTACTTGGAGATCCGGCAACTGGAGACACAAGCGGACCCCACTGGCAGGCTGCTG GACGCCTGGCAGGGACGCCCTGGCGCCTCTGTAGGCCGACTGCTCGAGCTGCTTACCAAG CTGGGCCGCGACGACGTGCTGCTGGAGCTGGGACCCAGCATTGAGGAGGATTGCCAAAAG TATATCTTGAAGCAGCAGCAGGAGGAGGCTGAGAAGCCTTTACAGGTGGCCGCTGTAGAC AGCAGTGTCCCACGGACAGCAGAGCTGGCGGGCATCACCACACTTGATGACCCCCTGGGG CATATGCCTGAGCGTTTCGATGCCTTCATCTGCTATTGCCCCAGCGACATCCAGTTTGTG CAGGAGATGATCCGGCAACTGGAACAGACAAACTATCGACTGAAGTTGTGTGTGTCTGAC CGCGATGTCCTGCCTGGCACCTGTGTCTGGTCTATTGCTAGTGAGCTCATCGAAAAGAGT GCCGCCGGATGGTGGTGGTTGTCTCTGATGATTACCTGCAGAGCAAGGAATGTGACTNCC AGACCAAATTGCACTCAGCCTCTCTTCAGGTGCCCATCAGAAGCGACTGATCCCCCATCA GTACCAGGGCATGAAGAAAGAGCTCCCCAGCATCCTCGAGGTCATCACTGTCTGCGACTA CACCAACCCCTGCACCAAT >OriGene 3' read for NM_002468 unedited
ATGGCCGCGGCCGCATTCTAGATCGAGTTTTTTTTTTTTTTTTTTTTCCAGGTAGNAAAT TATTTATTATTATAAACTCAGGATGCAAGATATATTCCAGGATATAGGAAGAATGGCAAA TATCGGCTTTTCTCAAATATCTTTGAAATTATTTTAATGCGTACAAAACATGTAGAAAAT GCCTCTTGAGATGGCTTTAAAATGCCCAGTATTAAAGGGGGACAGGTGCATGGCAGCTAA ATGCCTCAACAAGATCATGCAGAGAGGGGCATCCATTCCCTCCCAAGATCCTAAGAAAAG GTACCTTGCTCCAGCCTGGCTGAAAGTGGAGCAAAGATATGCATTTTCTATTGGATTTAG GGTCCTAGGGTCTGTCCTGGGGCACAGACACCTAAGACCATGGCACCTTCTCCCCAGAGG ACAGCCTGAGGGTAAAGTATAAATTGCTCTGGGAAGGAGAGAGGGAGAGAACAGCTGTGT CTGCAGTTCATTGTTGTGTGAGTTTAAGCAGCTCTCTTCCTCTCTCTGTGCTTCACTAGA GGTATAAATACTGGTACATTGGGTCCTTTCCAGAGTTTGGTTTCAATGAGTAGGGACACA AGAGAAAAGGAATAGATGAGTGCCCAATTTTTGTTCAGGGACATGGTTAGGCTCCCTCAG TGATGGGACTTTCCCACCTAGCTGTTCCTGGGAGCTGTACCTAGAANAACGTGTGTATGC TGGTGCCTGTGTGTGTGAGAGTACATGTCTGTACATATATGTNGTGNGTCTGTATGTGAG TCTGTATGTGCCCATGTGCCCACAAGCTTTTGGGCANGAGGCTTTATATGGTCGCTGTTT GTAACAAATNACTTTGTAGGGCATCAGGTACAAAAGTTGTGGNNAGCTCTCTGCANGTGG CCAGGGAGAANGCCTCCTGCTCACATCATACGGGACTCATCCCAGACTATACTGATGATA TGCAGAGCCAGNATCCTTTCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002468 |
| Insert Size | 2550 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002468.2, NP_002459.1 |
| RefSeq Size | 2862 bp |
| RefSeq ORF | 891 bp |
| Locus ID | 4615 |
| UniProt ID | Q99836 |
| Domains | TIR, DEATH |
| Protein Families | Druggable Genome |
| Protein Pathways | Apoptosis, Toll-like receptor signaling pathway |
| Gene Summary | This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202253 | MYD88 (Myc-DDK-tagged)-Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2 |
CNY 3,600.00 |
|
| RC202253L1 | Lenti ORF clone of Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC202253L2 | Lenti ORF clone of Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2, mGFP tagged |
CNY 6,000.00 |
|
| RC202253L3 | Lenti ORF clone of Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202253L4 | Lenti ORF clone of Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2, mGFP tagged |
CNY 6,000.00 |
|
| RC229151 | MYD88 (Myc-DDK-tagged)-Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2 |
CNY 3,600.00 |
|
| RG202253 | MYD88 (tGFP-tagged) - Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2 |
CNY 5,200.00 |
|
| RG229151 | MYD88 (tGFP-tagged) - Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2 |
CNY 5,200.00 |
|
| SC327786 | MYD88 (untagged)-Human myeloid differentiation primary response gene (88) (MYD88) |
CNY 6,270.00 |
