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p95 NBS1 (NBN) (NM_002485) Human Untagged Clone
CNY 8,296.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AT-V1; AT-V2; ATV; NBS; NBS1; P95 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118613 sequence for NM_002485 edited (data generated by NextGen Sequencing)
ATGTGGAAACTGCTGCCCGCCGCGGGCCCGGCAGGAGGAGAACCATACAGACTTTTGACT GGCGTTGAGTACGTTGTTGGAAGGAAAAACTGTGCCATTCTGATTGAAAATGATCAGTCG ATCAGCCGAAATCATGCTGTGTTAACTGCTAACTTTTCTGTAACCAACCTGAGTCAAACA GATGAAATCCCTGTATTGACATTAAAAGATAATTCTAAGTATGGTACCTTTGTTAATGAG GAAAAAATGCAGAATGGCTTTTCCCGAACTTTGAAGTCGGGGGATGGTATTACTTTTGGA GTGTTTGGAAGTAAATTCAGAATAGAGTATGAGCCTTTGGTTGCATGCTCTTCTTGTTTA GATGTCTCTGGGAAAACTGCTTTAAATCAAGCTATATTGCAACTTGGAGGATTTACTGTA AACAATTGGACAGAAGAATGCACTCACCTTGTCATGGTATCAGTGAAAGTTACCATTAAA ACAATATGTGCACTCATTTGTGGACGTCCAATTGTAAAGCCAGAATATTTTACTGAATTC CTGAAAGCAGTTGAGTCCAAGAAGCAGCCTCCACAAATTGAAAGTTTTTACCCACCTCTT GATGAACCATCTATTGGAAGTAAAAATGTTGATCTGTCAGGACGGCAGGAAAGAAAACAA ATCTTCAAAGGGAAAACATTTATATTTTTGAATGCCAAACAGCATAAGAAATTGAGTTCC GCAGTTGTCTTTGGAGGTGGGGAAGCTAGGTTGATAACAGAAGAGAATGAAGAAGAACAT AATTTCTTTTTGGCTCCGGGAACGTGTGTTGTTGATACAGGAATAACAAACTCACAGACC TTAATTCCTGACTGTCAGAAGAAATGGATTCAGTCAATAATGGATATGCTCCAAAGGCAA GGTCTTAGACCTATTCCTGAAGCAGAAATTGGATTGGCGGTGATTTTCATGACTACAAAG AATTACTGTGATCCTCAGGGCCATCCCAGTACAGGATTAAAGACAACAACTCCAGGACCA AGCCTTTCACAAGGCGTGTCAGTTGATGAAAAACTAATGCCAAGCGCCCCAGTGAACACT ACAACATACGTAGCTGACACAGAATCAGAGCAAGCAGATACATGGGATTTGAGTGAAAGG CCAAAAGAAATCAAAGTCTCCAAAATGGAACAAAAATTCAGAATGCTTTCACAAGACGCA CCCACTGTAAAGGAGTCCTGCAAAACAAGCTCTAATAATAATAGTATGGTATCAAATACT TTGGCTAAGATGAGAATCCCAAACTATCAGCTTTCACCAACTAAATTGCCAAGTATAAAT AAAAGTAAAGATAGGGCTTCTCAGCAGCAGCAGACCAACTCCATCAGAAACTACTTTCAG CCGTCTACCAAAAAAAGGGAAAGGGATGAAGAAAATCAAGAAATGTCTTCATGCAAATCA GCAAGAATAGAAACGTCTTGTTCTCTTTTAGAACAAACACAACCTGCTACACCCTCATTG TGGAAAAATAAGGAGCAGCATCTATCTGAGAATGAGCCTGTGGACACAAACTCAGACAAT AACTTATTTACAGATACAGATTTAAAATCTATTGTGAAAAATTCTGCCAGTAAATCTCAT GCTGCAGAAAAGCTAAGATCAAATAAAAAAAGGGAAATGGATGATGTGGCCATAGAAGAT GAAGTATTGGAACAGTTATTCAAGGACACAAAACCAGAGTTAGAAATTGATGTGAAAGTT CAAAAACAGGAGGAAGATGTCAATGTTAGAAAAAGGCCAAGGATGGATATAGAAACAAAT GACACTTTCAGTGATGAAGCAGTACCAGAAAGTAGCAAAATATCTCAAGAAAATGAAATT GGGAAGAAACGTGAACTCAAGGAAGACTCACTATGGTCAGCTAAAGAAATATCTAACAAT GACAAACTTCAGGATGATAGTGAGATGCTTCCAAAAAAGCTGTTATTGACTGAATTTAGA TCACTGGTGATTAAAAACTCTACTTCCAGAAATCCATCTGGCATAAATGATGATTATGGT CAACTAAAAAATTTCAAGAAATTCAAAAAGGTCACATATCCTGGAGCAGGAAAACTTCCA CACATCATTGGAGGATCAGATCTAATAGCTCATCATGCTCGAAAGAATACAGAACTAGAA GAGTGGCTAAGGCAGGAAATGGAGGTACAAAATCAACATGCAAAAGAAGAGTCTCTTGCT GATGATCTTTTTAGATACAATCCTTATTTAAAAAGGAGAAGATAA Clone variation with respect to NM_002485.4 1197 t=>c >OriGene 5' read for NM_002485 unedited
GGGCGGGCCGGGNNCGCTTTTTCTCCCCCCGGGGTTGAGATTTGTATACAACTTACTATA GGCGGCCGCGNAATTCGCACGAGGCCGACCGCAGGCGCCGTATCCGCGCTCGTCTAGCAG CCCCGGTTACGCGGTTGCACGTCGGCCCCAGCCCTGAGGAGCCGGACCGATGTGGAAACT GCTGCCCGCCGCGGGCCCGGCAGGAGGAGAACCATACAGACTTTTGACTGGCGTTGAGTA CGTTGTTGGAAGGAAAAACTGTGCCATTCTGATTGAAAATGATCAGTCGATCAGCCGAAA TCATGCTGTGTTAACTGCTAACTTTTCTGTAACCAACCTGAGTCAAACAGATGAAATCCC TGTATTGACATTAAAAGATAATTCTAAGTATGGTACCTTTGTTAATGAGGAAAAAATGCA GAATGGCTTTTCCCGAACTTTGAAGTCGGGGGATGGTATTACTTTTGGAGTGTTTGGAAG TAAATTCAGAATAGAGTATGAGCCTTTGGTTGCATGCTCTTCTTGTTTAGATGTCTCTGG GAAAACTGCTTTAAATCAAGCTATATTGCAACTTGGAGGATTTACTGTAAACAATTGGAC AGAAGAATGCACTCACCTTGTCATGGTATCAGTGAAAGTTACCATTAAAACAATATGTGC ACTCATTTGTGGACGTCCAATTGTAAAGCCAGAATATTTTACTGAATTCCTGAAAGCAGT TGAGTCCAAGAAGCAGCCTCCACAAATTGAAAGTTTTACCCACCTCTTGATGAACCATCT ATTGGAAAGTAAAATGTTGATCTGTCAGGACGGCAGGAAAGACAACAAATCTTCAAAAGG AAAACATTTTATTTTTTGGATGCCAAACAGCATAAGAAATTGGGTTCCGCCATTGGTTTT TGAAAGTGGGGAACCTTGGTTGTTACTCAAGGAGATGAAGAAAAACCTAATTTCTTTTTG GCTCCCGGAACCTGTGTTGTTGAACC >OriGene 3' read for NM_002485 unedited
CCGCGGTCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTAGGGGAAAAGGATTTTTTACTAATTGGCAAGGGAATTTAATGAGGAAA GGATAATTTTTTCAATAAACAGGGTTACAATGACTGGATACTTGTTTGGGGGAAAAAAAA AACCCTGATCCATAATTCACAACATACATTTCAATTCAGGGGGGATCACAAATTTAAAAA TTTAAAGTTTTTTTAATAGAGCAAAATTTTTGAAATTTTGGGGTTAAATTGGAGAGAAAA AATTTCAAACCAAAGAAAAAAATAAATTTGACCTTGTCAAAATTTAAAACTTTTTTTCTT CAAAAAACATAAAAAAAACAGTCAAGCCACAAACTAGGGGTAATATCTCAATACCTATAT CCGACAAAAAACTTGCATTTAAAATGTATAAAAAATTTCTATGACCCAATTATTGCTTTC AGGGATTTACAAATTAAAACCAAAATGAAACATCCCTACCCACCGATTGGAATGGTTAAA AAGGAAAAATACTGACAACACCAATATTTGTAAAGACAGGAGGTCCCAAAACTCTCATTC ATTATATTCATAAATTGACAAATATAAAAACTGCTATAGTAGGGCAGTCTTCCTTATAAG GGATTGTGGGCATTACANAAAACAATATTAATCTGGGCATTATATTCCTTAACTGTAAAA TGGAGACCATATGTTCCACCAGCTTCACTTTGGAATTTATGAACCTGGCCTTTTAAGAAA CTCAAAAGACTCCCTTTTATCCACCTAATATGCCCTGGAAATTCTACCTTTAAAGTTTCC CTGTTCTTTTCCATGTCCTACCACTATTATTATTTAAGGGTCCTAACCTCTTTATATTAT TTCAATAATTCAACCTGGGCCCAATGCGCTGTGANAAAAAATTGCAGAATGGCTCCCCCC ATGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002485 |
| Insert Size | 4420 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002485.4, NP_002476.2 |
| RefSeq Size | 4639 bp |
| RefSeq ORF | 2265 bp |
| Locus ID | 4683 |
| UniProt ID | O60934 |
| Domains | FHA |
| Protein Families | Druggable Genome |
| Protein Pathways | Homologous recombination |
| Gene Summary | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214682 | NBN (Myc-DDK-tagged)-Human nibrin (NBN) |
CNY 5,520.00 |
|
| RC214682L1 | Lenti ORF clone of Human nibrin (NBN), Myc-DDK-tagged |
CNY 7,920.00 |
|
| RC214682L2 | Lenti ORF clone of Human nibrin (NBN), mGFP tagged |
CNY 5,890.00 |
|
| RC214682L3 | Lenti ORF clone of Human nibrin (NBN), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC214682L4 | Lenti ORF clone of Human nibrin (NBN), mGFP tagged |
CNY 7,920.00 |
|
| RG214682 | NBN (tGFP-tagged) - Human nibrin (NBN) |
CNY 7,120.00 |
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