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Mad (MXD1) (NM_002357) Human Untagged Clone
CAT＃: SC118694
MXD1 (untagged)-Human MAX dimerization protein 1 (MXD1), transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BHLHC58; MAD; MAD1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002357, the custom clone sequence may differ by one or more nucleotides
ATGGCGGCGGCGGTTCGGATGAACATCCAGATGCTGCTGGAGGCGGCCGACTATCTGGAGCGGCGGGAGA GAGAAGCTGAACATGGTTATGCCTCCATGTTACCATACAATAACAAGGACAGAGATGCCTTAAAACGGAG GAACAAATCCAAAAAGAATAACAGCAGTAGCAGATCAACTCACAATGAAATGGAGAAGAATAGACGGGCT CATCTTCGCTTGTGCCTGGAGAAGTTGAAGGGGCTGGTGCCACTTGGACCCGAATCAAGTCGACACACTA CGTTGAGTTTATTAACAAAAGCCAAATTGCACATAAAGAAACTTGAAGATTGTGACAGAAAAGCCGTTCA CCAAATCGACCAGCTTCAGCGAGAGCAGCGACACCTGAAGAGGCAGCTGGAGAAGCTGGGCATTGAGAGG ATCCGGATGGACAGCATCGGCTCCACCGTCTCCTCGGAGCGCTCCGACTCCGACAGGGAAGAAATCGACG TTGACGTGGAGAGCACGGACTATCTCACAGGTGATCTGGACTGGAGCAGCAGCAGTGTGAGCGACTCTGA CGAGCGGGGCAGCATGCAGAGCCTCGGCAGTGATGAGGGCTATTCCAGCACCAGCATCAAGAGAATAAAG CTGCAGGACAGTCACAAGGCGTGTCTTGGTCTCTAA >OriGene 5' read for NM_002357 unedited
TTCCCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA ATTCGGCACGAGGCGGCGGTGGCGGCTGCTGCTCTGCTCCGGGTTCTGTCACTGTGTCGG CGGTGCCCAGCTCACTGGCCCCCTCCCTCTCTTGTCGAGCGTGGTTGCCAGAGAGGCTCC CTCAGCCCTGCTCCGCGGGGTCCACAGCGGGCTCCACAGCGGGCTCCATAGCGGGCTCCA CAGCGGTCCGGCGGCGGCAGCGAGCCCGTGGGCAGTGGGGGTTGGTCCCGTGGCTCCGGC CCCCGGTGCAGAATGGCGGCGGCGGTTCGGATGAACATCCAGATGCTGCTGGAGGCGGCC GACTATCTGGAGCGGCGGGAGAGAGAAGCTGAACATGGTTATGCCTCCATGTTACCATAC AATAACAAGGACAGAGATGCCTTANAACGGAGGAACAAATCCAAAAAGAATAACAGCAGT AGCAGATCAACTCACAATGAAATGGAGAAGAATAGACGGGCTCATCTTCGCTTGTGCCTG GAGAAAGTGAAGGNNGCTGTGCCACTTGNACCCCGATCAAGTCGACACACTACGTTGAGT TTATTAAACAAAGCCAATTGCACATAAAGAAACTTTTGAGATGTGACAGANAAGCCGTTC ACCAAATCGACCAGCTTCAGCGAGAGCAGCGACACCTGAAGAAGCAGCTGNAGAAGCTGG GCATTGANAGNATCCNGATGGACACNATCGCTCCACCGTCTCTCGNAGCGCTCCACTCCG ACAGGAAAAATCNACGTTGACCTGAAAGCACGACTATCTACAAGTGATCTGNACTGGAGC ACCACANTGTTGACCACTTTGAAAGCGGGCCACATGCAAACCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002357 |
| Insert Size | 3700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002357.2, NP_002348.1 |
| RefSeq Size | 5587 bp |
| RefSeq ORF | 666 bp |
| Locus ID | 4084 |
| UniProt ID | Q05195 |
| Domains | HLH |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eµ-miR-155 transgenic mouse model
,Sukhinder K. Sandhu, Stefano Volinia, Stefan Costinean, Marco Galasso, Reid Neinast, Ramasamy Santhanam, Mark R. Parthun, Danilo Perrotti, Guido Marcucci, Ramiro Garzon, and Carlo M. Croce,
PNAS, Dec 2012; 109: 20047 - 20052.
[MXD1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210520 | MXD1 (Myc-DDK-tagged)-Human MAX dimerization protein 1 (MXD1), transcript variant 1 |
CNY 2,400.00 |
|
| RC210520L1 | Lenti ORF clone of Human MAX dimerization protein 1 (MXD1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC210520L2 | Lenti ORF clone of Human MAX dimerization protein 1 (MXD1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RC210520L3 | Lenti ORF clone of Human MAX dimerization protein 1 (MXD1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210520L4 | Lenti ORF clone of Human MAX dimerization protein 1 (MXD1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG210520 | MXD1 (tGFP-tagged) - Human MAX dimerization protein 1 (MXD1), transcript variant 1 |
CNY 4,000.00 |
