United States
Germany
Japan
United Kingdom
China
alpha 1 Catenin (CTNNA1) (NM_001903) Human Untagged Clone
CAT＃: SC118935
CTNNA1 (untagged)-Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1)
CNY 6,640.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAP102; MDPT2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118935 sequence for NM_001903 edited (data generated by NextGen Sequencing)
ATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATC AGGACTCTGGCAGTTGAGAGACTGTTGGAGCCTCTTGTTACACAGGTTACAACCCTTGTA AACACCAATAGTAAAGGGCCCTCTAATAAGAAGAGAGGTCGTTCTAAGAAGGCCCATGTT TTGGCTGCATCTGTTGAACAAGCAACTGAGAATTTCTTGGAGAAGGGGGATAAAATTGCG AAGGAGAGCCAGTTTCTCAAGGAGGAGCTTGTGGCTGCTGTAGAAGATGTTCGAAAACAA GGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGAAG CGAGGCAACATGGTTCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATT TTGGCTGACATGGCAGATGTCTACAAATTACTTGTTCAGCTGAAAGTTGTGGAAGATGGT ATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCCTA AAACCTGAAGTGGATAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGAT GTTGGCCATCGTGATCAGATGGCTGCAGCTAGAGGAATCCTGCAGAAGAACGTTCCGATC CTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCAAC AGGGACCTGATATACAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAG GCCACTGCCTCAGACGATGCCTCACAGCACCAGGGTGGAGGAGGAGGAGAACTGGCATAT GCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGCGC TTTAGGCCTTCCCTGGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCC GACTCGTCCTGCACGCGTGATGACCGTCGTGAGCGAATTGTGGCAGAGTGTAATGCTGTC CGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATGCTGGACGTAAAGAAAGA AGTGATGCACTCAATTCTGCAATAGATAAAATGACCAAGAAGACCAGGGACTTGCGTAGA CAGCTCCGCAAAGCTGTCATGGACCACGTTTCAGATTCTTTCCTGGAAACCAATGTTCCA CTTTTGGTATTGATTGAAGCTGCAAAGAATGGAAATGAGAAAGAAGTTAAGGAGTATGCC CAAGTTTTCCGTGAACATGCCAACAAATTGATTGAGGTTGCCAACTTGGCCTGTTCCATC TCAAATAATGAAGAAGGTGTAAAGCTTGTTCGAATGTCTGCAAGCCAGTTAGAAGCCCTC TGTCCTCAGGTTATTAATGCTGCACTGGCTTTAGCAGCAAAACCACAGAGTAAACTGGCC CAAGAGAACATGGATCTTTTTAAAGAACAATGGGAAAAACAAGTCCGTGTTCTCACAGAT GCTGTCGATGACATTACTTCCATTGATGACTTCTTGGCTGTCTCAGAGAATCACATTTTG GAAGATGTGAACAAATGTGTCATTGCTCTCCAAGAGAAGGATGTGGATGGCCTGGACCGC ACAGCTGGTGCAATTCGAGGCCGGGCAGCCCGGGTCATTCACGTAGTCACCTCAGAGATG GACAACTATGAGCCAGGAGTCTACACAGAGAAGGTTCTGGAAGCCACTAAGCTGCTCTCC AACACAGTCATGCCACGTTTTACTGAGCAAGTAGAAGCAGCCGTGGAAGCCCTCAGCTCG GACCCTGCCCAGCCCATGGATGAGAATGAGTTTATCGATGCTTCCCGCCTGGTATATGAT GGCATCCGGGACATCAGGAAAGCAGTGCTGATGATAAGGACCCCTGAGGAGTTGGATGAC TCTGACTTTGAGACAGAAGATTTTGATGTCAGAAGCAGGACGAGCGTCCAGACAGAAGAC GATCAGCTGATAGCTGGCCAGAGTGCCCGGGCGATCATGGCTCAGCTTCCCCAGGAGCAA AAAGCGAAGATTGCGGAACAGGTGGCCAGCTTCCAGGAAGAAAAGAGCAAGCTGGATGCT GAAGTGTCCAAATGGGACGACAGTGGCAATGACATCATTGTGCTGGCCAAGCAGATGTGC ATGATTATGATGGAGATGACAGACTTTACCCGAGGTAAAGGACCACTCAAAAATACATCG GATGTCATCAGTGCTGCCAAGAAAATTGCTGAGGCAGGATCCAGGATGGACAAGCTTGGC CGCACCATTGCAGACCATTGCCCCGACTCGGCTTGCAAGCAGGACCTGCTGGCCTACCTG CAACGCATCGCCCTCTACTGCCACCAGCTGAACATCTGCAGCAAGGTCAAGGCCGAGGTG CAGAATCTCGGCGGGGAGCTTGTTGTCTCTGGGGTGGACAGCGCCATGTCCCTGATCCAG GCAGCCAAGAACTTGATGAATGCTGTGGTGCAGACAGTGAAGGCATCCTACGTCGCCTCT ACCAAATACCAAAAGTCACAGGGTATGGCTTCCCTCAACCTTCCTGCTGTGTCATGGAAG ATGAAGGCACCAGAGAAAAAGCCATTGGTGAAGAGAGAGAAACAGGATGAGACACAGACC AAGATTAAACGGGCATCTCAGAAGAAGCACGTGAACCCGGTGCAGGCCCTCAGCGAGTTC AAAGCTATGGACAGCATCTAA Clone variation with respect to NM_001903.2 >OriGene 5' read for NM_001903 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATT CGGCACGAGGCCGGACTGGAGGGAGACAAAGCAGCGCCCGTCTGCTTCGGGCCTCTGGAA TTTAGCGCTCGCCCAGCTAGCCGCAGAAATGACTGCTGTCCATGCAGGCAACATAAACTT CAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGGAGCC TCTTGTTACACAGGTTACAACCCTTGTAAACACCAATAGTAAAGGGCCCTCTAATAAGAA GAGAGGTCGTTCTAAGAAGGCCCATGTTTTGGCTGCATCTGTTGAACAAGCAACTGAGAA TTTCTTGGAGAAGGGGGATAAAATTGCGAAGGAGAGCCAGTTTCTCAAGGAGGAGCTTGT GGCTGCTGTAGAAGATGTTCGAAAACAAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTT CGCAGATGATCCCTGCTCTTCTGTGAAGCGAGGCAACATGGTTCGGGCAGCTCGAGCTTT GCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAATTACT TGTTCAGCTGAAAGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACA AGACTTANGAATCCAGTATAAAGCCCTAAAACCTGAAGTGGATAAGCTGAACATTATGGC AGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAGCTAG AGGAATCCTGCAGAAAGACGNTNNCGATCCTCTATACTGCATCCCCAGCATGCCTACAGC ACCCTGGATGTCGCAGCCTATAAGGCCCACAGGGACCTGATATANCAGCAGCTGCAGCAA GGCGGTCACG >OriGene 3' read for NM_001903 unedited
TAAAAGACAACTTTCATTAATGGTCCTGCAGCAGCGTACATTAGTAATTATAACAATGCA TTAAAATTTTCATTTCATGTCATAGAGAATCAGTTTTCTTCATGATACATTATGTTTTAC TGAGTGAGTTTGTCCCTCCAGAGACCTTTCTGGGAACATGCCTTCTCCAGGGACTGCTTC CTAAGATGCCCAGGTTGCTTACCACAGGTCATCTTTGGTCATTTAAAAGCAGTCAAGCTG TCTGGACTGCACCCTCTCAACTGAAGTTGAGCCAAATTCCCTTCTCTCAAACCCTAACGC CGCCATCACTAAGAGAATGGGCATCTCGGCTTGGTCAGAGCATTACTAACAAGCTAATGT GGGATTCTCTTTGGTTATGAATTTTTATTTTTATTTAAGCATACAAAAAATACAGCTAGA AGTAGGCTCCTGCATTCTAAAAGCATTTTTAATCAACTTAAACTATGTTCTTGGAAAATT CACCACCTGGACTGGTTCAGTCTGCCCATTTCCCTGTGGAATCTAGTATCAGTGTTGTAT TTAGCAAATTCATTTGAGTGACGAACAGTGACTGATATTCAGGAGCCCCGAGGGGTGGGG GCGGCCGGCCTGGGCAGACTTAGATGCTGTCCATAGCTTTGAACTCGCTGAGGGCCTGCA CCGGGTTCACGTGCTTCTTCTGAGATGCCCGTTTAATCTTGGGCTGTGTCTCATCCTGTT TCTCTCTCTTCACCAATGGCTTTTTCTCTGGTGCCTTCATCTTCCATGACACAGCAGGAA AGTTGAGGGNAAGCCATACCCTGTGACTTTNGGNTATTGGGTANAAGCGACGTAGGATGC CTTCACTGTCTGGACCACAGCATCATCAAATTCTGGGCTGCTGGATAGGGACATGGCGCT GTTCACCCCAGAACAACAGCTTCCCGCCGGATTTGGCCCTNGCCTTGCACTTTTGNAAAT GTAACCTGGGGCATAAAGGGAATGCCTTAAGGTAGGCAACAGCCTCTTTTCACCGATACG GAAGGTGTCAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001903 |
| Insert Size | 3670 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001903.2, NP_001894.2 |
| RefSeq Size | 3778 bp |
| RefSeq ORF | 2721 bp |
| Locus ID | 1495 |
| UniProt ID | P35221 |
| Domains | Vinculin |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction |
| Gene Summary | This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
DLC1 Interaction with a-Catenin Stabilizes Adherens Junctions and Enhances DLC1 Antioncogenic Activity
,Veenu Tripathi, Nicholas C. Popescu, and Drazen B. Zimonjic,
Mol. Cell. Biol., Jun 2012; 32: 2145 - 2159.
[CTNNA1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201766 | CTNNA1 (Myc-DDK-tagged)-Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1) |
CNY 6,632.00 |
|
| RC201766L1 | Lenti ORF clone of Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1), Myc-DDK-tagged |
CNY 9,032.00 |
|
| RC201766L2 | Lenti ORF clone of Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1), mGFP tagged |
CNY 5,890.00 |
|
| RC201766L3 | Lenti ORF clone of Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201766L4 | Lenti ORF clone of Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1), mGFP tagged |
CNY 9,032.00 |
|
| RG201766 | CTNNA1 (tGFP-tagged) - Human catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1) |
CNY 8,232.00 |
其它alpha 1 Catenin产品
