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CCR3 (NM_001837) Human Untagged Clone
CAT＃: SC118980
CCR3 (untagged)-Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1
CNY 3,656.00
CNY 7,220.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CC-CKR-3; C C CKR3; CD193; CKR 3; CKR3; CMKBR3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001837, RT-PCR generated
ATGACAACCTCACTAGATACAGTTGAGACCTTTGGTACCACATCCTACTATGATGACGTG GGCCTGCTCTGTGAAAAAGCTGATACCAGAGCACTGATGGCCCAGTTTGTGCCCCCGCTG TACTCCCTGGTGTTCACTGTGGGCCTCTTGGGCAATGTGGTGGTGGTGATGATCCTCATA AAATACAGGAGGCTCCGAATTATGACCAACATCTACCTGCTCAACCTGGCCATTTCGGAC CTGCTCTTCCTCGTCACCCTTCCATTCTGGATCCACTATGTCAGGGGGCATAACTGGGTT TTTGGCCATGGCATGTGTAAGCTCCTCTCAGGGTTTTATCACACAGGCTTGTACAGCGAG ATCTTTTTCATAATCCTGCTGACAATCGACAGGTACCTGGCCATTGTCCATGCTGTGTTT GCCCTTCGAGCCCGGACTGTCACTTTTGGTGTCATCACCAGCATCGTCACCTGGGGCCTG GCAGTGCTAGCAGCTCTTCCTGAATTTATCTTCTATGAGACTGAAGAGTTGTTTGAAGAG ACTCTTTGCAGTGCTCTTTACCCAGAGGATACAGTATATAGCTGGAGGCATTTCCACACT CTGAGAATGACCATCTTCTGTCTCGTTCTCCCTCTGCTCGTTATGGCCATCTGCTACACA GGAATCATCAAAACGCTGCTGAGGTGCCCCAGTAAAAAAAAGTACAAGGCCATCCGGCTC ATTTTTGTCATCATGGCGGTGTTTTTCATTTTCTGGACACCCTACAATGTGGCTATCCTT CTCTCTTCCTATCAATCCATCTTATTTGGAAATGACTGTGAGCGGAGCAAGCATCTGGAC CTGGTCATGCTGGTGACAGAGGTGATCGCCTACTCCCACTGCTGCATGAACCCGGTGATC TACGCCTTTGTTGGAGAGAGGTTCCGGAAGTACCTGCGCCACTTCTTCCACAGGCACTTG CTCATGCACCTGGGCAGATACATCCCATTCCTTCCTAGTGAGAAGCTGGAAAGAACCAGC TCTGTCTCTCCATCCACAGCAGAGCCGGAACTCTCTATTGTGTTTTAG >OriGene 5' read for NM_001837 unedited
TTTTAGTTGGGTTGGGNNGCTTANNCGATGGCGTTTAGGGCTTTGACGTGAATCTGCAGA AATCGGCTTGAGAAGTGAAATGACACACCCACTAGATACAGTTGAGACCTTTGGTACCAC ATCCTACTATGATGACGTGGGCCTGCTCTGTGAAAAAGCTGATACCAGAGCACTGATGGC CCAGTTTGTGCCCCCGCTGTACTCCCTGTAGTCATTGTGGGCCTCTTGGGCAATGTGGTG GTGGTGATGATCCTCATAAAATACAGGAGGCTCCGAATTATGACCAACATCTACCTGCTC AACCTGGCCATTTCGGACCTGCTCTTCCTCGTCACCCTTCCATTCTGGATCCACTATGTC AGGGGGCATAACTGGGTTTTTGGCCATGGCATGTGTAAGCTCCTCTCAGGGTTTTATCAC ACAGGCTTGTACAGCGAGATCTTTTTCATAATCCTGCTGACAATCGACAGGTACCTGGCC ATTGTCCATGCTGTGTTTGCCCTTCGAGCCCGGACTGTCACTTTTGGTGTCATCACCAGC ATCGTCACCTGNGGCCTGACAGTGCTAGCAGCTCTTCCTGAATTTATCTTCTATGAGACT GAACAGTTGTTTGAAGAGACTCTTTGCAGTGCTCTTTACCCAGACGATACAGTATATAGC TGGGAGCATTTNCACACTCTGAGGATGACCATCTTCTGTCTCCGTCTCCCTCTGCTCGTT ATGGCCATCTGCTACACAGGATCATCAAAACGCTGCTGAAGTGCCCCAGTAAAAAAAAAT ACAAGGCCATCCCGGCTCATTTTTGTCATCATGGCCGGGGTTTATTCATTTTCTGGAAAC CCTTAAAAGGTGGGCTATTCCTTCTCTCTTGCTAATAATCCATCTTATTTGGAAAGACTG TGAGCGGAGAAGGAACTGAACTGGAAAGCCGGGGAAN >OriGene 3' read for NM_001837 unedited
GAAAGCCCATTGGNGATGGCAACTTCCAGGACCAGNAAAGCACTGGGGNAGGGTCACAGG AATGCCACCCGGGTTCTGTTCAGGAAAAGCTATGACCGCGGCCGCAATCTAGAGTCGACA AGCTTGATATCGGTACCGAGCTCGGATCCACTAGTAACGGCCGCCAGTGTGCTGGAATTC GGCTTCTGACCTAAAACACAATAGAGAGTTCCGGCTCTGCTGTGGATGGAGAGACAGAGA TGGTTCTTTCAAGCTTCTCACTAGGAAGGAATGGGACGTAACTGCCCAGGTGCAAGAGCA AGTGCCTGTGGAAGAAGTGGCACCGGTACTTCCGGAACCTCTCTCCAACCACAGCGTAAA TGACCCGGATCATGCACCCAAAGGGAGAAGGCAATCATATATATCGCCGCCGGGAACCGA TACAAATGCTTAAAACCTTTCGGGAATTGGCTATGTTATGTGGAGTGATGATGAAAATAG CAGCATATCCATAAGAGAAAACCGGTATCTGCGTGTGTTTTTATTAGGGAGAAGGAAAAA TATACGAATTATGCGGGCGGGGGGGCGGGAAAGAAATATTTCGAGTTTTGAGGGATGCGG TGTTTTAAAAAAAAGGGCGGGCGATGGAAAGGGTATTTTTTTTTTCGAAAACTCTCCCGC CAAAACCTCCTCTTTTATCAGACGAAATAAGGGGTAATAGAATGAAGGAAGAATGACGCG AGGGTGTAAGCCGCGCCGGAAAAGGCCGGGGCGCTTAAGTTTCTTTAGATTATTTAAAGA TTTTTCCCCCGCTACATAGAAGTATAGCCCCTCCTATAAAAAAACATACCCGCGCGCGGC GAAGCGGCGGAAATAAACCAAAAAAAAAACGGGCCGGAAAAAATCGCTTGATATCGTGTG CGGAGGTT |
| Restriction Sites | Please inquire |
| ACCN | NM_001837 |
| Insert Size | 1200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001837.2, NP_001828.1 |
| RefSeq Size | 1945 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 1232 |
| UniProt ID | P51677 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] Transcript Variant: This variant (1) represents the longest transcript. It encodes the same isoform (1) as variant 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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The Lupane-type Triterpene 30-Oxo-calenduladiol Is a CCR5 Antagonist with Anti-HIV-1 and Anti-chemotactic Activities
,Jonathan Barroso-González, Nabil El Jaber-Vazdekis, Laura García-Expósito, José-David Machado, Rafael Zárate, Ángel G. Ravelo, Ana Estévez-Braun, and Agustín Valenzuela-Fernández,
J. Biol. Chem., Jun 2009; 284: 16609 - 16620.
[CCR3]
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Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8
,PC Jensen, R Nygaard, S Thiele, A Elder, G Zhu, R Kolbeck, S Ghosh, TW Schwartz, and MM Rosenkilde,
Mol Pharmacol. 2007 Aug;72(2):327-40.
[CCR3]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210337 | CCR3 (Myc-DDK-tagged)-Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1 |
CNY 3,656.00 |
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| RC210337L1 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
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| RC210337L2 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC210337L3 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210337L4 | Lenti ORF clone of Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG210337 | CCR3 (tGFP-tagged) - Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1 |
CNY 5,256.00 |
