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C1S (NM_001734) Human Untagged Clone
CAT＃: SC119071
C1S (untagged)-Human complement component 1, s subcomponent (C1S), transcript variant 2
CNY 5,048.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EDSPD2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001734, the custom clone sequence may differ by one or more nucleotides
ATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTATGCTGAGCCTACCATGTATGGGGAGATCC TGTCCCCTAACTATCCTCAGGCATATCCCAGTGAGGTAGAGAAATCTTGGGACATAGAAGTTCCTGAAGG GTATGGGATTCACCTCTACTTCACCCATCTGGACATTGAGCTGTCAGAGAACTGTGCGTATGACTCAGTG CAGATAATCTCAGGAGACACTGAAGAAGGGAGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTC CAATTGTGGAAGAGTTCCAAGTCCCATACAACAAACTCCAGGTGATCTTTAAGTCAGACTTTTCCAATGA AGAGCGTTTTACGGGGTTTGCTGCATACTATGTTGCCACAGACATAAATGAATGCACAGATTTTGTAGAT GTCCCTTGTAGCCACTTCTGCAACAATTTCATTGGTGGTTACTTCTGCTCCTGCCCCCCGGAATATTTCC TCCATGATGACATGAAGAATTGCGGAGTTAATTGCAGTGGGGATGTATTCACTGCACTGATTGGGGAGAT TGCAAGTCCCAATTATCCCAAACCATATCCAGAGAACTCAAGGTGTGAATACCAGATCCGGTTGGAGAAA GGGTTCCAAGTGGTGGTGACCTTGCGGAGAGAAGATTTTGATGTGGAAGCAGCTGACTCAGCGGGAAACT GCCTTGACAGTTTAGTTTTTGTTGCAGGAGATCGGCAATTTGGTCCTTACTGTGGTCATGGATTCCCTGG GCCTCTAAATATTGAAACCAAGAGTAATGCTCTTGATATCATCTTCCAAACTGATCTAACAGGGCAAAAA AAGGGCTGGAAACTTCGCTATCATGGAGATCCAATGCCCTGCCCTAAGGAAGACACTCCCAATTCTGTTT GGGAGCCTGCGAAGGCAAAATATGTCTTTAGAGATGTGGTGCAGATAACCTGTCTGGATGGGTTTGAAGT TGTGGAGGGACGTGTTGGTGCAACATCTTTCTATTCGACTTGTCAAAGCAATGGAAAGTGGAGTAATTCC AAACTGAAATGTCAACCTGTGGACTGTGGCATTCCTGAATCCATTGAGAATGGTAAAGTTGAAGACCCAG AGAGCACTTTGTTTGGTTCTGTCATCCGCTACACTTGTGAGGAGCCATATTACTACATGGAAAATGGAGG AGGTGGGGAGTATCACTGTGCTGGTAACGGGAGCTGGGTGAATGAGGTGCTGGGCCCGGAGCTGCCGAAA TGTGTTCCAGTCTGTGGAGTCCCCAGAGAACCCTTTGAAGAAAAACAGAGGATAATTGGAGGATCCGATG CAGATATTAAAAACTTCCCCTGGCAAGTCTTCTTTGACAACCCATGGGCTGGTGGAGCGCTCATTAATGA GTACTGGGTGCTGACGGCTGCTCATGTTGTGGAGGGAAACAGGGAGCCAACAATGTATGTTGGGTCCACC TCAGTGCAGACCTCACGGCTGGCAAAATCCAAGATGCTCACTCCTGAGCATGTGTTTATTCATCCGGGAT GGAAGCTGCTGGAAGTCCCAGAAGGACGAACCAATTTTGATAATGACATTGCACTGGTGCGGCTGAAAGA CCCAGTGAAAATGGGACCCACCGTCTCTCCCATCTGCCTACCAGGCACCTCTTCCGACTACAACCTCATG GATGGGGACCTGGGACTGATCTCAGGCTGGGGCCGAACAGAGAAGAGAGATCGTGCTGTTCGCCTCAAGG CGGCAAGGTTACCTGTAGCTCCTTTAAGAAAATGCAAAGAAGTGAAAGTGGAGAAACCCACAGCAGATGC AGAGGCCTATGTTTTCACTCCTAACATGATCTGTGCTGGAGGAGAGAAGGGCATGGATAGCTGTAAAGGG GACAGTGGTGGGGCCTTTGCTGTACAGGATCCCAATGACAAGACCAAATTCTACGCAGCTGGCCTGGTGT CCTGGGGGCCCCAGTGTGGGACCTATGGGCTCTACACACGGGTAAAGAACTATGTTGACTGGATAATGAA GACTATGCAGGAAAATAGCACCCCCCGTGAGGACTAA >OriGene 5' read for NM_001734 unedited
TCAGTAATTTGTAATACGACTCACTATTAGGGCGGCCGCGNAATTCGCACCAGGCTGGCC GGAGGTTCCTGCAGAGGAGCGTCAAGGCCCTGTGCTGCTGTCCCTGGGGGCCAGAGGGGT TGCCCAGCATGCCCACTGGCAGGAGAGAGGGAACTGACCCACTTGCTCCTACCAGCTTCT GAAGGCTCCAAAGTCCGGAGGTGCAGAAAGCCAGGACCAAGATACAGGCAGCTCACCAGG GTGGACAAATCGCCAGAGATGTGGTGCATTGTCCTGTTTTCACTTTTGGCATGGGTTTAT GCTGAGCCTACCATGTATGGGGAGATCCTGTCCCCTAACTATCCTCAGGCATATCCCAGT GAGGTAGAGAAATCTTGGGACATAGAAGTTCCTGAAGGGTATGGGATTCACCTCTACTTC ACCCATCTGGACATTGAGCTGTCAGAGAACTGTGCGTATGACTCAGTGCAGATAATCTCA GGAGACACTGAAGAAGGGAGGCTCTGTGGACAGAGGAGCAGTAACAATCCCCACTCTCCA ATTGTGGAAGAGTTCCAAGTCCCATACAACAAACTCCAGGTGATCTTTAAGTCAGACTTT TCCAATGAAGAGCGTTTTACGGAGTTTGCTGCATACTATGTTGCCACAGACATAAATGAA TGCACAGATTCTGTAGATGTCCCTTGTAGCCACTTCTGCAACAATTTCATTGGTGGTTAC TTCTGCTCCTGCCCCCCGGAATATTTNCTCCATGATGACATGAAGAATTGCGGAGTTAAT TGCAGTGGGGATGTATTCACTGCACTGATTGGNGAGATTNGCAGTTCCATTATTCCAAAC CTATCCAGAGACTCAAGTGTGAATACAGATCCGTNTGGAGATAGGCTNCAGTGGGGGTGA CCTTGCGAGAGATATNTGATGTGGAGCACTGACTCACGGAAACTGCTGACAGTTATTTTT GTGCAGAGATCGCATTGGTCCTACGTGTCAG >OriGene 3' read for NM_001734 unedited
NGAGCCATTGGCGATGTGCAACTTCCCAGGTCCAGNAAAGCACTGGGGNAGGGTCACAGG GCTGCCACCCGGGTATCTGTTGCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAGTC GAGTTTTTTTTTTTTTTTTTTGCTTATAAACATCCTTTATTGTACATAGACAGTGGATAC TGAGAATGATCAAGTAAATGGAATTTTGAACAGGTAAAGAGGAAACAAAGAATTAAGGTA TCCCTGTGGAATAGTGCAAGAAAGGAGTGCCCCACCCATAGTGTTATCTACAATAGGTAC TCCGGGGAAAGGACCCCAAGGAGTCAGACCACAAATGTATGACCAGCACAATTCTATGAT CAAACTCTACCTCTAGCAAGGCGTCTCAACAATCAAGTTCTATTTAAATCATTCGCTCGT GTCTTCTTTCAGTCATGATGAAATAATGAGAATATCATAAGGAACAGAAGGTAATGCATT GGTCACCACCCTTGGAGAGGCTGGTGGGATGTATCTGGATTAGTCCTCACGGGGGGTGCT ATTTTCCTGCATAGTCTTCATTATCCAGTCAACATAGTTCTTTACCCGTGTGTAGAGCCC ATAGGTCCCACACTGGGGCCCCCAGGACACCAGGCCAGCTGCGTAGAATTTGGTCTTGTC ATTGGGATCCTGTACAGCAAAGGCCCCACCACTGTCCCCTTTACAGCTATCCATGCCCTT CTCTCCTCCAGCACAGATCATGTTAGGAGTGAAAACATAGGCCTCTGCATCTGCTGTGGG TTTCTCCACTTTCACTTCTTTGCATTTTCTTAAAGGAGCTACAGGTAACCTTGCCGCCTT TGAGCGAACAGCACGATCTCTCTTCTCTGTNTCGCCCCAGCCTGAGATCAGTCCCAGGTC CCCATCCATGATGTTGTANTCAGAAAGAGTGCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001734 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001734.2, NP_001725.1 |
| RefSeq Size | 2714 bp |
| RefSeq ORF | 2067 bp |
| Locus ID | 716 |
| UniProt ID | P09871 |
| Domains | CCP, CUB, Tryp_SPc, EGF_CA, EGF |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Complement and coagulation cascades, Systemic lupus erythematosus |
| Gene Summary | This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Classical complement pathway components c1r and c1s: purification from human serum and in recombinant form and functional characterization
,Rossi, V;Bally, I;Lacroix, M;Arlaud, GJ;Thielens, NM;,
Methods Mol. Biol. 43-60
,PubMed ID 24218249
[C1S]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218963 | C1S (Myc-DDK-tagged)-Human complement component 1, s subcomponent (C1S), transcript variant 2 |
CNY 5,040.00 |
|
| RC218963L1 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 2, Myc-DDK-tagged |
CNY 7,440.00 |
|
| RC218963L2 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC218963L3 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC218963L4 | Lenti ORF clone of Human complement component 1, s subcomponent (C1S), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG218963 | C1S (tGFP-tagged) - Human complement component 1, s subcomponent (C1S), transcript variant 2 |
CNY 6,640.00 |
