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Catalase (CAT) (NM_001752) Human Untagged Clone
CNY 3,936.00
CNY 7,220.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119081 sequence for NM_001752 edited (data generated by NextGen Sequencing)
ATGGCTGACAGCCGGGATCCCGCCAGCGACCAGATGCAGCACTGGAAGGAGCAGCGGGCC GCGCAGAAAGCTGATGTCCTGACCACTGGAGCTGGTAACCCAGTAGGAGACAAACTTAAT GTTATTACAGTAGGGCCCCGTGGGCCCCTTCTTGTTCAGGATGTGGTTTTCACTGATGAA ATGGCTCATTTTGACCGAGAGAGAATTCCTGAGAGAGTTGTGCATGCTAAAGGAGCAGGG GCCTTTGGCTACTTTGAGGTCACACATGACATTACCAAATACTCCAAGGCAAAGGTATTT GAGCATATTGGAAAGAAGACTCCCATCGCAGTTCGGTTCTCCACTGTTGCTGGAGAATCG GGTTCAGCTGACACAGTTCGGGACCCTCGTGGGTTTGCAGTGAAATTTTACACAGAAGAT GGTAACTGGGATCTCGTTGGAAATAACACCCCCATTTTCTTCATCAGGGATCCCATATTG TTTCCATCTTTTATCCACAGCCAAAAGAGAAATCCTCAGACACATCTGAAGGATCCGGAC ATGGTCTGGGACTTCTGGAGCCTACGTCCTGAGTCTCTGCATCAGGTTTCTTTCTTGTTC AGTGATCGGGGGATTCCAGATGGACATCGCCACATGAATGGATATGGATCACATACTTTC AAGCTGGTTAATGCAAATGGGGAGGCAGTTTATTGCAAATTCCATTATAAGACTGACCAG GGCATCAAAAACCTTTCTGTTGAAGATGCGGCGAGACTTTCCCAGGAAGATCCTGACTAT GGCATCCGGGATCTTTTTAACGCCATTGCCACAGGAAAGTACCCCTCCTGGACTTTTTAC ATCCAGGTCATGACATTTAATCAGGCAGAAACTTTTCCATTTAATCCATTCGATCTCACC AAGGTTTGGCCTCACAAGGACTACCCTCTCATCCCAGTTGGTAAACTGGTCTTAAACCGG AATCCAGTTAATTACTTTGCTGAGGTTGAACAGATAGCCTTCGACCCAAGCAACATGCCA CCTGGCATTGAGGCCAGTCCTGACAAAATGCTTCAGGGCCGCCTTTTTGCCTATCCTGAC ACTCACCGCCATCGCCTGGGACCCAATTATCTTCATATACCTGTGAACTGTCCCTACCGT GCTCGAGTGGCCAACTACCAGCGTGATGGCCCGATGTGCATGCAGGACAATCAGGGTGGT GCTCCAAATTACTACCCCAACAGCTTTGGTGCTCCGGAACAACAGCCTTCTGCCCTGGAG CACAGCATCCAATATTCTGGAGAAGTGCGGAGATTCAACACTGCCAATGATGATAACGTT ACTCAGGTGCGGGCATTCTATGTGAACGTGCTGAATGAGGAACAGAGGAAACGTCTGTGT GAGAACATTGCCGGCCACCTGAAGGATGCACAAATTTTCATCCAGAAGAAAGCGGTCAAG AACTTCACTGAGGTCCACCCTGACTACGGGAGCCACATCCAGGCTCTTCTGGACAAGTAC AATGCTGAGAAGCCTAAGAATGCGATTCACACCTTTGTGCAGTCCGGATCTCACTTGGCG GCAAGGGAGAAGGCAAATCTGTGA Clone variation with respect to NM_001752.3 1167 c=>t >OriGene 5' read for NM_001752 unedited
GGTTGNAATTTGTATACGACTCACTATAGGGCGGCCGCGCAATTCGCACGAGGACGAGCC GAGGCCTCCTGCAGTGTTCTGCACAGCAAACCGCACGCTATGGCTGACAGCCGGGATCCC GCCAGCGACCAGATGCAGCACTGGAAGGAGCAGCGGGCCGCGCAGAAAGCTGATGTCCTG ACCACTGGAGCTGGTAACCCAGTAGGAGACAAACTTAATGTTATTACAGTAGGGCCCCGT GGGCCCCTTCTTGTTCAGGATGTGGTTTTCACTGATGAAATGGCTCATTTTGACCGAGAG AGAATTCCTGAGAGAGTTGTGCATGCTAAAGGAGCAGGGGCCTTTGGCTACTTTGAGGTC ACACATGACATTACCAAATACTCCAAGGCAAAGGTATTTGAGCATATTGGAAAGAAGACT CCCATCGCAGTTCGGTTCTCCACTGTTGCTGGAGAATCGGGTTCAGCTGACACAGTTCGG GACCCTCGTGGGTTTGCAGTGAAATTTTACACAGAAGATGGTAACTGGGATCTCGTTGGA AATAACACCCCCATTTTCTTCATCAGGGATCCCATATTGTTTCCATCTTTTATCCACAGC CAAAAGAGAAATCCTCAGACACATCTGAAGGATCCGGACATGGTCTGGGACTTCTGGAGC CTACGTCCTGAGTCTCTGCATCACGTTTCTTTCTTGTTCAGTGATCCGGGGATTCCAGAT GGACATCGCCACATGAATGGATATGGATCACATACTCTCCAGCCTGTTTAATGCCAAATG GGGAGGCAGTTTATTGCAAATTCCATTATAAGACTGACCACGGCATCAAAAACCTTTCTG TTGAAGATCCGGCGAGACTTTCCCANGAAGAATCTGACTATGGCATCCGGGGATCTTTTT ACCGCCATTGCCCCAGNAAAGTCN >OriGene 3' read for NM_001752 unedited
NNNTTTTTAGCTATGGACCCGCGGCCGCAATCTAGNGTCGAGTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTACGGACAGATTATTTATTGGAAAAATGTAAGCAATTACA AATTGATCTGTTGGGAAATCAGGGCTGAATTAACATTAATGTAACTCCAGGGAAAAAAAT GAATTTGATCAATTATTATCATTAATAAACATTAAGCCATGACGGGGCTCAAGTTATCTT CTGATGACACTGCTGTATTAAATGTACTTTTCCTATGAAAACCTTAAAAAAATAAAAATT TCTGAGGAAAACATCTTTATCTTTTCTTTTTATATATTTATAGCCATATTTTAATATAAT AGGCCATGAGGGGATATGTAAACATACATAATTTCAACAAATTTTGTCAAATAAAATCAT ATTTCTAGCTAGAAACTTGCCTTCTAATCATTTTAAATGAATAATCCAATCATCCGTCAA AACAAATTTTTTTTTTAAATGACTGTTAAATCCTAACCTTCATTTTCCCCTGGGGAAATA GCATTAAAATTGTTACACAATCTGCTATAGAAAGTGGGATTCTCTATTTTGAAGCCACTA GCTTGCATTTGCACATCTAGCACAGGAGAATCTTCATCCAGTGATGAGCGGGTTACACCG GATGAACGCTAAGCTTCGCTGCACAGGTGCAGGGCCCCGGCCTCACAGATTTGCCTTCTC CCTTGCCGCCAAGTGAGATCCGGACTGCACAAAGGTGTGAATCGCATTCTAAGGCTTTTC AGCATTGCACTTGCCCAAAAAGCCTGAATGTGCCTCCCGTATCCAGGTGGACCTCAGTGA AGTCTTGACCGTTTTCTCTGGAAGAAAATTTGGCATCCTTCAGGTGCCCGCAATGTTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001752 |
| Insert Size | 2150 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001752.2, NP_001743.1 |
| RefSeq Size | 2305 bp |
| RefSeq ORF | 1584 bp |
| Locus ID | 847 |
| UniProt ID | P04040 |
| Domains | catalase |
| Protein Families | Druggable Genome |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS), Metabolic pathways, Methane metabolism, Tryptophan metabolism |
| Gene Summary | This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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The effects of catalase and kisspeptin overexpression on amyloid peptide toxicity
,Chilumuri, A;,
Thesis
[CAT]
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Immunocytochemical staining of endogenous nuclear proteins with the HIS-1 anti-poly-histidine monoclonal antibody: A potential source of error in His-tagged protein detection
,Chilumuri, A;Markiv, A;Milton, NG;,
Acta Histochem.
,PubMed ID 24835186
[CAT]
|
|
Autophagy Is a Cell Self-Protective Mechanism Against Arsenic-Induced Cell Transformation
,Tao Zhang, Yuanlin Qi, Mingjun Liao, Mei Xu, Kimberley A. Bower, Jacqueline A. Frank, Han-Ming Shen, Jia Luo, Xianglin Shi, and Gang Chen,
Toxicol. Sci., Dec 2012; 130: 298 - 308.
[CAT]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210763 | CAT (Myc-DDK-tagged)-Human catalase (CAT) |
CNY 3,928.00 |
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| RC210763L1 | Lenti ORF clone of Human catalase (CAT), Myc-DDK-tagged |
CNY 6,328.00 |
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| RC210763L2 | Lenti ORF clone of Human catalase (CAT), mGFP tagged |
CNY 6,460.00 |
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| RC210763L3 | Lenti ORF clone of Human catalase (CAT), Myc-DDK-tagged |
CNY 6,328.00 |
|
| RC210763L4 | Lenti ORF clone of Human catalase (CAT), mGFP tagged |
CNY 6,328.00 |
|
| RG210763 | CAT (tGFP-tagged) - Human catalase (CAT) |
CNY 5,528.00 |
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