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CIRBP (NM_001280) Human Untagged Clone
CAT＃: SC119359
CIRBP (untagged)-Human cold inducible RNA binding protein (CIRBP), transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIRP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001280 edited
ATGGCATCAGATGAAGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAG TCGCTGGAGCAGGTCTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGAC AGGGAGACCCAGAGATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCT AAGGATGCCATGATGGCCATGAATGGGAAGTCTGTAGATGGACGGCAGATCCGAGTAGAC CAGGCAGGCAAGTCGTCAGACAACCGATCCCGTGGGTACCGTGGTGGCTCTGCCGGGGGC CGGGGCTTCTTCCGTGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGAGGAGGGGAC CGAGGCTATGGGGGGAACCGGTTCGAGTCCAGGAGTGGGGGCTACGGAGGCTCCAGAGAC TACTATAGCAGCCGGAGTCAGAGTGGTGGCTACAGTGACCGGAGCTCGGGCGGGTCCTAC AGAGACAGTTATGACAGTTACGCTACACACAACGAGTAA >OriGene 5' read for NM_001280 unedited
TGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTCGGGTCGTTGTGGTGCG CTGTCTTCCCGCTTGCGTCAGGGACCTGCCCGACTCAGTGGCCGCCATGGCATCAGATGA AGGCAAACTTTTTGTTGGAGGGCTGAGTTTTGACACCAATGAGCAGTCGCTGGAGCAGGT CTTCTCAAAGTACGGACAGATCTCTGAAGTGGTGGTTGTGAAAGACAGGGAGACCCAGAG ATCTCGGGGATTTGGGTTTGTCACCTTTGAGAACATTGACGACGCTTAGGATGCCATGAT GGCCATGAATGGGAAGTCTGTAGATGGACGGCAGATCCGAGTAGACCAGGCAGGCAAGTC GTCAGACAACCGATCCCGTGGGTACCGTGGTGGCTCTGCCGGGGGCCGGGGCTTCTTCCG TGGGGGCCGAGGACGGGGCCGTGGGTTCTCTAGAGGAGGAGGGGACCGAGGCTATGGGGG GAACCGGTTCGAGTCCAGGAGTGGGGGCTACGGAGGCTCCAGAGACTACTATAGCAGCCG GAGTCAGAGTGGTGGCTACAGTGACCGGAGCTCGGGCGGGTCCTACAGAGACAGTTATGA CAGTTACGCTACACACAACGAGTAAAAACCCTTCCTGCTCAAGATCGTCCTTCCAATGGG CTGTGTGTTTAAAGATTGTGGGAGCTTCGCTGAACGTTAATGTGTAGTAAATGCACCTCC TTGTATTCCCACTTTCGAGTCTTTTTTCGGGTTCTGATCTTGTCAAACCCAGCCTGACCG CTTCTGACGCCCGGGATGGCCTCNGTACTAGACTTTCTTTTTAAAGGAAGGGGTTGGTTT TTTTTTGGGGGGGTTTTCAAACATTTTGAAAAGCATTTACTTTTTGACCCAGCCATGAGT TAAAAGGGGGGGGGGGGGGGGGGGGGNNNNNNNNGGGNNNNNNAAAAAA >OriGene 3' read for NM_001280 unedited
GCGGCACGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTCATTTAACACGNGTCTTTT AATCGGCTTCGTAAAGCCAAAAAAAACTGCGTACAAGAATTCCTCAGCCACTGCAAATAC AACATCGATGGAGTATGCGTACGTCTTCCAGTAAAAAAGGACAATATAAATAAACATCTT CAAGAACCTCTCAGGGACGTCTGCACGTCTACTGTGGGGCGCACAGCACAGATGGACGCA GGGGCTGGGGCTCCAGGGCAGTTGCTGCCACACCCGCCGGGGTCCTACCACACTACACTC AGAAACGTCACACGGAGTTGGAAAAAAGCCACAGCTTGCTCAGCTTCCGACAAAGAGCGG ATTCACAGTCCGTTCGATCTCAGAGAAGTGAGTGGGGCACCCACTTCATGGGGCCAACCC CACTAAAAAAAAAAAGGCAACGCAACCAAAAACTAAAACAAAAACCAAAAACCCACACAA CCCCCGATTTTTTTGAAAACTCATGGCTCGTGGTCAAAAAAGTAAATGCTTTTCAAAATG TTTTGAAAACCCTCAAAAAAAAACAGCACTTCCTTAAAAAGAAAAGTCTAGTAACGAGGC CATCCCGGCGTCAGAAGCGGTCAGGCTGGGTTTGACAAGATCAGAACCGAAATGACTACG AAAGTGGGAATACAAGGAGGTGCATTTACTACACATTAACGTTCAGCGAAGCTCCCACAA TCTTTAAACACACAGCCATTGGAAGGACGATCTTGAGCAGGAAGGGTTTTTACTCGTTGT GTGTAGCGTAACTGTCATAACTGTCTCTGTNAGACCCGNCCCGAGCTCGGTCACTGTAGC CACCACTCTGACTNNCGCTGCTATAGTAGTCTCTGGAGCCTNCGTAGCCCCACTCCTGGA CTCGNACCGGTNTCCCNCATAGCCTCGGTCCCCTCCTCTCTAGAAAACCCACGCCCGTNN CTCGCCCCAGNAAGAGCCCGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001280 |
| Insert Size | 1260 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001280.1, NP_001271.1 |
| RefSeq Size | 1322 bp |
| RefSeq ORF | 519 bp |
| Locus ID | 1153 |
| UniProt ID | Q14011 |
| Domains | RRM, RRM_1 |
| Gene Summary | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) uses alternate splice sites at the 3' end, resulting in a novel 3' coding region and 3' UTR, compared to variant 5. It encodes isoform 1, which has a shorter and distinct C-terminus, compared to isoform 3. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Tumor necrosis factor and transforming growth factor beta regulate clock genes by controlling the expression of the cold inducible RNA - binding protein (CIRBP)
,Lopez, MA;Meier, D;Mueller, AF;Franken, P;Fujita, J;Fontana, A;,
J. Biol. Chem. Dec 2013.
,PubMed ID 24337574
[CIRBP]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201639 | CIRBP (Myc-DDK-tagged)-Human cold inducible RNA binding protein (CIRBP), transcript variant 1 |
CNY 2,400.00 |
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| RC201639L1 | Lenti ORF clone of Human cold inducible RNA binding protein (CIRBP), transcript variant 1, Myc-DDK-tagged |
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| RC201639L2 | Lenti ORF clone of Human cold inducible RNA binding protein (CIRBP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
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| RC201639L3 | Lenti ORF clone of Human cold inducible RNA binding protein (CIRBP), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC201639L4 | Lenti ORF clone of Human cold inducible RNA binding protein (CIRBP), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
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| RG201639 | CIRBP (tGFP-tagged) - Human cold inducible RNA binding protein (CIRBP), transcript variant 1 |
CNY 4,000.00 |
