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BMP2 (NM_001200) Human Untagged Clone
CAT＃: SC119392
BMP2 (untagged)-Human bone morphogenetic protein 2 (BMP2)
CNY 3,656.00
CNY 6,460.00
| Cited in 8 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BDA2; BMP2A; SSFSC; SSFSC1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119392 sequence for NM_001200 edited (data generated by NextGen Sequencing)
ATGGTGGCCGGGACCCGCTGTCTTCTAGCGTTGCTGCTTCCCCAGGTCCTCCTGGGCGGC GCGGCTGGCCTCGTTCCGGAGCTGGGCCGCAGGAAGTTCGCGGCGGCGTCGTCGGGCCGC CCCTCATCCCAGCCCTCTGACGAGGTCCTGAGCGAGTTCGAGTTGCGGCTGCTCAGCATG TTCGGCCTGAAACAGAGACCCACCCCCAGCAGGGACGCCGTGGTGCCCCCCTACATGCTA GACCTGTATCGCAGGCACTCGGGTCAGCCGGGCTCACCCGCCCCAGACCACCGGTTGGAG AGGGCAGCCAGCCGAGCCAACACTGTGCGCAGCTTCCACCATGAAGAATCTTTGGAAGAA CTACCAGAAACGAGTGGGAAAACAACCCGGAGATTCTTCTTTAATTTAAGTTCTATCCCC ACGGAGGAGTTTATCACCTCAGCAGAGCTTCAGGTTTTCCGAGAACAGATGCAAGATGCT TTAGGAAACAATAGCAGTTTCCATCACCGAATTAATATTTATGAAATCATAAAACCTGCA ACAGCCAACTCGAAATTCCCCGTGACCAGTCTTTTGGACACCAGGTTGGTGAATCAGAAT GCAAGCAGGTGGGAAAGTTTTGATGTCACCCCCGCTGTGATGCGGTGGACTGCACAGGGA CACGCCAACCATGGATTCGTGGTGGAAGTGGCCCACTTGGAGGAGAAACAAGGTGTCTCC AAGAGACATGTTAGGATAAGCAGGTCTTTGCACCAAGATGAACACAGCTGGTCACAGATA AGGCCATTGCTAGTAACTTTTGGCCATGATGGAAAAGGGCATCCTCTCCACAAAAGAGAA AAACGTCAAGCCAAACACAAACAGCGGAAACGCCTTAAGTCCAGCTGTAAGAGACACCCT TTGTACGTGGACTTCAGTGACGTGGGGTGGAATGACTGGATTGTGGCTCCCCCGGGGTAT CACGCCTTTTACTGCCACGGAGAATGCCCTTTTCCTCTGGCTGATCATCTGAACTCCACT AATCATGCCATTGTTCAGACGTTGGTCAACTCTGTTAACTCTAAGATTCCTAAGGCATGC TGTGTCCCGACAGAACTCAGTGCTATCTCGATGCTGTACCTTGACGAGAATGAAAAGGTT GTATTAAAGAACTATCAGGACATGGTTGTGGAGGGTTGTGGGTGTCGCTAG Clone variation with respect to NM_001200.2 261 a=>g;570 a=>t >OriGene 5' read for NM_001200 unedited
TCTTTACCCGCCCGTTGNCGCATAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCG AATTCGGCACGAGGCCCAGGATGGCTGCCCCGAGCCATGGGCCGCGGCGGAGCTAGCGCG GAGCGCCCGACCCTCGACCCCCGAGTCCCGGAGCCGGCCCCGCGCGGGGCCACGCGTCCC TCGGGCGCTGGTTCCTAAGGAGGACGACAGCACCAGCTTCTCCTTTCTCCCTTCCCTTCC CTGCCCCGCACTCCTCCCCCTGCTCGCTGTTGTTGTGTGTCAGCACTTGGCTGGGGACTT CTTGAACTTGCAGGGAGAATAACTTGCGCACCCCACTTTGCGCCGGTGCCTTTGCCCCAG CGGAGCCTGCTTCGCCATCTCCGAGCCCCACCGCCCCTCCACTCCTCGGCCTTGCCCGAC ACTGAGACGCTGTTCCCAGCGTGAAAAGAGAGACTGCGCGGCCGGCACCCGGGAGAAGGA GGAGGCAAAGAAAAGGAACGGACATTCGGTCCTTGCGCCAGGTCCTTTGACCAGAGTTTT TCCATGTGGACGCTCTTTCAATGGACGTGTCCCCGCGTGCTTCTTAGACGGACTGCGGTC TCCTAAAGGTCGACCATGGTGGCCGGGACCCGCTGTCTTCTAGCGTTGCTGCTTCCCCAG GTCCTCCTGGGCGGCGCGGCTGGCCTCGTTCCGGAGCTGGGCCGCATGATGTTCGCGGCG GCGTCGTCAGGCCGNCCCTCATCCCAGCCCTCTGACGATGTCCTGAGCGAGTTCGAGTTG CAGCTGCTCAGCATGTTTCGCCCTGAACAGAGACCCACCCCAGCATGGACGCCGTGGNTG CCCCCCTACATGCTAGACCTGTATCGCAAGCACTCGGGNTCAGCCGGGCTCACCCGNCCC >OriGene 3' read for NM_001200 unedited
GGAAAATCAGGTACGTCGCCGCAATTCNAGATCGAGTTTTTTTTTTTTTTTTTNTCTAAA ATATATATATATATATATATTTATGTATTTAATTTTGCTGTACTAGCGACACCCACAACC CTCCACAACCATGTCCTGATAGTTCTTTAATACAACCTTTTCATTCTCGTCAAGGTACAG CATCGAGATAGCACTGAGTTCTGTCGGGACACAGCATGCCTTAGGAATCTTAGAGTTAAC AGAGTTGACCAACGTCTGAACAATGGCATGATTAGTGGAGTTCAGATGATCAGCCAGAGG AAAAGGGCATTCTCCGTGGCAGTAAAAGGCGTGATACCCCGGGGGAGCCACAATCCAGTC ATTCCACCCCACGTCACTGAAGTCCACGTACAAAGGGTGTCTCTTACAGCTGGACTTAAG GCGTTTCCGCTGTTTGTGTTTGGCTTGACGTTTTTCTCTTTTGTGGAGAGGATGCCCTTT TCCATCATGGCCAAAAGTTACTAGCAATGGCCTTATCTGTGACCAGCTGTGTTCATCTTG GTGCAAAGACCTGCTTATCCTAACATGTCTCTTGAAGACACCTTTGTTCTCCTCCAAGTG GGCCACTTCCACCACGAATCCATGGTTGGCGTGTCCCTGTGCAGTCCACCCGATCACAGC GGGGGGTGACATCAAAAACTTTCCCACCCGCTTTGGATTCTGGATTCACCAACCCTGTTT GTTCAAAAAGACTGGTCCACGGGGAAATTTCAAGTTGGCCGGTTGCAGGGTTTTAGGATT TCATAAAATATTAATTCCGGGGAAGGAAACTGCTATTGTTTCCTAAAACATTTTGCATCT GGTTTTCGGAAAACCGGAAACTCTGCTGGGGGGATAAACCTCCTCCGCGGGGGTAGAACC TTAATTAAGAAAAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001200 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001200.1, NP_001191.1 |
| RefSeq Size | 1547 bp |
| RefSeq ORF | 1191 bp |
| Locus ID | 650 |
| UniProt ID | P12643 |
| Domains | TGFb_propeptide, TGF-beta |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transmembrane |
| Protein Pathways | Acute myeloid leukemia, Basal cell carcinoma, Cytokine-cytokine receptor interaction, Endocytosis, Hedgehog signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, TGF-beta signaling pathway |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] |
Citations (8)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Comparison of in-situ versus ex-situ delivery of polyethylenimine-BMP-2 polyplexes for rat calvarial defect repair via intraoperative bioprinting.
,null,
Biofabrication
,PubMed ID 36322966
[BMP2]
|
|
Non-viral gene delivery embedded in biomimetically mineralized matrices for bone tissue engineering
,Acri, T;Laird, NZ;Jaidev, LR;Meyerholz, DK;Salem, AK;Shin, K;,
Tissue Eng Part A
,PubMed ID 33086991
[BMP2]
|
|
A Multi-Functional Implant Induces Bone Formation in a Diabetic Model
,Khorsand, B;Acri, TM;Do, AV;Femino, JE;Petersen, E;Fredericks, DC;Salem, AK;,
Adv Healthc Mater
,PubMed ID 32815306
[BMP2]
|
|
Histone-targeted gene transfer of bone morphogenetic protein-2 enhances mesenchymal stem cell chondrogenic differentiation
,Munsell, EV;Kurpad, DS;Freeman, TA;Sullivan, MO;,
Acta Biomater
,PubMed ID 29481871
[BMP2]
|
|
Modification of Human Umbilical Cord Blood Stem Cells Using Polyethylenimine Combined with Modified TAT Peptide to Enhance BMP-2 Production
,Wang, Y;You, C;Wei, R;Zu, J;Song, C;Li, J;Yan, J;,
BioMed Research International
,PubMed ID 28951869
[BMP2]
|
|
Regeneration of bone using nanoplex delivery of FGF-2 and BMP-2 genes in diaphyseal long bone radial defects in a diabetic rabbit model
,Khorsand, B;Nicholson, N;Do, AV;Femino, JE;Martin, JA;Petersen, E;Guetschow, B;Fredericks, DC;Salem, AK;,
J Control Release
,PubMed ID 28069556
[BMP2]
|
|
Scaffold-mediated BMP-2 Minicircle DNA Delivery Accelerated Bone Repair in a Mouse Critical-Size Calvarial Defect Model
,Keeney, M;Chung, MT;Zielins, ER;Paik, KJ;McArdle, A;Morrison, SD;Ransom, RC;Barbhaiya, N;Atashroo, D;Jacobson, G;Zare, RN;Longaker, MT;Wan, DC;Yang, F;,
J Biomed Mater Res A
,PubMed ID 27059085
[BMP2]
|
|
BMP-2 signaling in ovarian cancer and its association with poor prognosis
,Cécile Le Page, Marie-Line Puiffe, Liliane Meunier, Magdalena Zietarska, Manon de Ladurantaye, Patricia N Tonin, Diane Provencher and Anne-Marie Mes-Masson,
Journal of Ovarian Research 2009, 2:4
[BMP2]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214586 | BMP2 (Myc-DDK-tagged)-Human bone morphogenetic protein 2 (BMP2) |
CNY 3,656.00 |
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| RC214586L1 | Lenti ORF clone of Human bone morphogenetic protein 2 (BMP2), Myc-DDK-tagged |
CNY 6,056.00 |
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| RC214586L2 | Lenti ORF clone of Human bone morphogenetic protein 2 (BMP2), mGFP tagged |
CNY 5,890.00 |
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| RC214586L3 | Lenti ORF clone of Human bone morphogenetic protein 2 (BMP2), Myc-DDK-tagged |
CNY 5,890.00 |
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| RC214586L4 | Lenti ORF clone of Human bone morphogenetic protein 2 (BMP2), mGFP tagged |
CNY 6,056.00 |
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| RG214586 | BMP2 (tGFP-tagged) - Human bone morphogenetic protein 2 (BMP2) |
CNY 5,256.00 |
