GABA A Receptor alpha 4 (GABRA4) (NM_000809) Human Untagged Clone
CAT#: SC119625
GABRA4 (untagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1
CNY 4,136.00
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119625 sequence for NM_000809 edited (data generated by NextGen Sequencing)
ATGGTTTCTGCCAAGAAGGTACCCGCGATCGCTCTGTCCGCCGGGGTCAGTTTCGCCCTC CTGCGCTTCCTGTGCCTGGCGGTTTGTTTAAACGAATCCCCAGGACAGAACCAAAAGGAG GAGAAATTGTGCACAGAAAATTTCACCCGCATCCTGGACAGTTTGCTCGATGGTTATGAC AACAGGCTGCGTCCTGGATTTGGGGGTCCTGTTACAGAAGTGAAAACTGACATATATGTC ACCAGCTTTGGACCTGTTTCTGATGTTGAAATGGAATACACAATGGATGTGTTCTTCAGG CAGACATGGATTGACAAAAGATTAAAATATGACGGCCCCATTGAAATTTTGAGATTGAAC AATATGATGGTAACGAAAGTGTGGACCCCTGATACTTTCTTCAGGAATGGAAAGAAATCT GTCTCACATAATATGACAGCTCCAAATAAGCTTTTTAGAATTATGAGAAATGGTACTATT TTATACACAATGAGACTCACCATAAGTGCGGAGTGTCCCATGAGATTGGTGGATTTTCCC ATGGATGGTCATGCATGCCCTTTGAAATTCGGGAGTTATGCCTATCCAAAGAGTGAGATG ATCTATACCTGGACAAAAGGTCCTGAGAAATCAGTTGAAGTTCCGAAGGAGTCTTCCAGC TTAGTTCAATATGATTTGATTGGGCAAACCGTATCAAGTGAAACCATCAAATCAATTACG GGTGAATATATTGTTATGACGGTTTACTTCCACCTCAGACGGAAGATGGGTTATTTTATG ATTCAGACCTATATTCCGTGCATTATGACAGTGATTCTTTCTCAAGTTTCATTTTGGATA AATAAAGAATCAGTTCCCGCTAGGACTGTATTTGGAATAACAACTGTCCTCACCATGACC ACACTAAGCATCAGTGCACGACATTCTTTGCCCAAAGTGTCCTATGCTACCGCCATGGAC TGGTTCATAGCTGTCTGCTTTGCTTTTGTATTTTCGGCCCTTATCGAGTTTGCTGCTGTC AACTATTTCACCAATATTCAAATGGAAAAAGCCAAAAGGAAGACATCAAAGCCCCCTCAG GAAGTTCCCGCTGCTCCAGTGCAGAGAGAGAAGCATCCTGAAGCCCCTCTGCAGAATACA AATGCCAATTTGAACATGAGAAAAAGAACAAATGCTTTGGTTCACTCTGAATCTGATGTT GGCAACAGAACTGAGGTGGGAAACCATTCAAGCAAATCTTCCACAGTTGTTCAAGAATCT TCTAAAGGCACACCTCGGTCTTACTTAGCTTCCAGTCCAAACCCATTCAGCCGTGCAAAT GCAGCTGAAACCATATCTGCAGCAAGAGCACTTCCATCTGCTTCTCCTACTTCTATCCGA ACTGGATATATGCCTCGAAAGGCTTCAGTTGGATCTGCTTCTACTCGTCACGTGTTTGGA TCAAGACTGCAGAGGATAAAGACCACAGTTAATACCATAGGGGCTACTGGGAAGTTGTCA GCTACTCCTCCTCCATCGGCTCCACCACCTTCTGGATCTGGCACAAGTAAAATAGACAAA TATGCCCGTATTCTCTTTCCAGTCACATTTGGGGCATTTAACATGGTTTATTGGGTTGTT TATTTATCTAAGGACACTATGGAGAAATCAGAAAGTCTAATGTAA Clone variation with respect to NM_000809.3 >OriGene 5' read for NM_000809 unedited
AACCCAATTCGCACGAGGAGTGTGCGCACGCCGCGGGAGCCTCTCTGCCCTCTCCTCGCA CCCTGCTCAGGGCATCTGAAGAGCCTGGAAACGTGAACAGGCTTGAAGTATGGCATGTTG CAAAGATGGTTTCTGCCAAGAAGGTACCCGCGATCGCTCTGTCCGCCGGGGTCAGTTTCT TCCTCCTGCGCTTCCTGTGCCTGGCGGTTTGTTTAAACGAATCCCCAGGACAGAACCAAA AGGAGGAGAAATTGTGCACAGAAAATTTCACCCGCATCCTGGACAGTTTGCTCGATGGTT ATGACAACAGGCTGCGTCCTGGATTTGGGGGTCCTGTTACAGAAGTGAAAACTGACATAT ATGTCACCAGCTTTGGACCTGTTTCTGATGTTGAAATGGAATACACAATGGATGTGTTCT TCAGGCAGACATGGATTGACAAAAGATTAAAATATGACGGCCCCATTGAAATTTTGAGAT TGAACAATATGATGGTAACGAAAGTGTGGACCCCTGATACTTTCTTCAGGAATGGAAAGA AATCTGTCTCACATAATATGACAGCTCCAAATAAGCTTTTTAGAATTATGAGAAATGGTA CTATTTTATACACAATGAGACTCACCATAAGTGCGGAGTGTCCCATGAGATTGGTGGATT TTCCCATGGATGGTCATGCATGCNCTTTGAAATTCGGGAGTTATGCCTATCCAAAGAGTG AGATGATCTATACCTGGACAAAAGGTCCTGAGAAATCAGTTGAAGTTTCGAAGGAGTCTT CCAGCTTAGTTCAATATGATTTGATTGGNGCAACCGTATCAAGTGAAACCATCAAATCAT TACGGGTGAATATATTGGTATGC >OriGene 3' read for NM_000809 unedited
NNTTTACTATGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTAC AAGTACTCTTTATTAAATATATACATATATACAGGTGTTACTGGACCTAATTTTACTAGA ATCAATTTTAAATTGGGGGGTTGGGACTGGGTGATTTCGACAGTATCTTTCAGCCTTAAA ATGTGTTGATTCTATGGAATACCTAGAAAGACAGCCAAGAATGATTTCTCAGATATGACT TACAATTAATATTTGGCATTTGCACAATTTTCAGGTATCAAAAACAACCATTATAAGGTA GTGCAATATCTGAAAAATCGATGCCAATTAACTACTATCACTTCTTTTCTATAAAAACAA AAAGAGAGAGAGAGATTTTGTCTGCAAGGTGGTCATTTCTATCAATATGTTCCCTAAAAC ACCCAGAACACATTCACTCATCCATTCCAGAGCAGATAGAGAGAAGCACAGAAGAAAATC TAGAGGCAATATGACAAAAAACCATACTTAGATTCAGCTGCATAGACAGTTGCAAAATTC TCAAGTAAGTTGTTAAGCCTACCTAATGAGAAAGAAGTCAGTAGATGAAAACCCTGATAA ATCACATAGCAGAGTCAGTGGCATCCTACCCGACAGCTATTTTTTTCTTTACTCCTTTCA TTTGCTGCTCTCTTAATTTAAAATATTCCCCTTATTATTAAACCTTAAAAAACTCCAAAA AAACAACATGATGACTGCCCAGAATACAGAACTACNGACACAAAACTCTTAAAATTTAGC ATTNCACTACCTAATATCTAGATCTATCTTGGGGAAAGCACCTGAAAAAGACTGTGCTCA GTTCTATGTCTGATGGATCTGGGATTCTGATCAAATCTACTTGGGACTCTGACAAATTGC GACGTTATCTATAAGGCTTAATTGGCTGAATTTACTTTCATACAA |
Restriction Sites | NotI-NotI |
ACCN | NM_000809 |
Insert Size | 4050 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000809.2, NP_000800.2 |
RefSeq Size | 11143 bp |
RefSeq ORF | 1665 bp |
Locus ID | 2557 |
UniProt ID | P48169 |
Domains | Neur_chan_memb, Neur_chan_LBD |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
Gene Summary | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207208 | GABRA4 (Myc-DDK-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1 |
CNY 4,128.00 |
|
RC207208L1 | Lenti-ORF clone of GABRA4 (Myc-DDK-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1 |
CNY 5,890.00 |
|
RC207208L2 | Lenti-ORF clone of GABRA4 (mGFP-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1 |
CNY 5,890.00 |
|
RC207208L3 | Lenti-ORF clone of GABRA4 (Myc-DDK-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1 |
CNY 5,890.00 |
|
RC207208L4 | Lenti-ORF clone of GABRA4 (mGFP-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1 |
CNY 5,890.00 |
|
RG207208 | GABRA4 (tGFP-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 4 (GABRA4), transcript variant 1 |
CNY 4,370.00 |
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