United States
Germany
Japan
United Kingdom
China
Metabotropic Glutamate Receptor 2 (GRM2) (NM_000839) Human Untagged Clone
CAT＃: SC119644
GRM2 (untagged)-Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1
CNY 6,392.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GLUR2; GPRC1B; mGlu2; MGLUR2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000839 edited
CGGCACGAGGCTTCGCATCTCTCTTCTTGTCTGTCCTTTCCTGGTCCCTGTTTCCTCCTC TCTTTGCCTTCGCTGCTTCTAATCTCATCCCCTGGAGACCCAGGTCTGCGGGACCCATCC ATCCCCTTTGGGGCCATGGGATCGCTGCTTGCGCTCCTGGCACTGCTGCTGCTGTGGGGT GCTGTGGCTGAGGGCCCAGCCAAGAAGGTGCTGACCCTGGAGGGAGACTTGGTGCTGGGT GGGCTGTTCCCAGTGCACCAGAAGGGCGGCCCAGCAGAGGACTGTGGTCCTGTCAATGAG CACCGTGGCATCCAGCGCCTGGAGGCCATGCTTTTTGCACTGGACCGCATCAACCGTGAC CCGCACCTGCTGCCTGGCGTGCGCCTGGGTGCACACATCCTCGACAGTTGCTCCAAGGAC ACACATGCGCTGGAGCAGGCACTGGACTTTGTGCGTGCCTCACTCAGCCGTGGTGCTGAT GGCTCACGCCACATCTGCCCCGACGGCTCTTATGCGACCCATGGTGATGCTCCCACTGCC ATCACTGGTGTTATTGGCGGTTCCTACAGTGATGTCTCCATCCAGGTGGCCAACCTCTTG AGGCTATTTCAGATCCCACAGATTAGCTACGCCTCTACCAGTGCCAAGCTGAGTGACAAG TCCCGCTATGACTACTTTGCCCGCACAGTGCCTCCTGACTTCTTCCAAGCCAAGGCCATG GCTGAGATTCTCCGCTTCTTCAACTGGACCTATGTGTCCACTGTGGCGTCTGAGGGCGAC TATGGCGAGACAGGCATTGAGGCCTTTGAGCTAGAGGCTCGTGCCCGCAACATCTGTGTG GCCACCTCGGAGAAAGTGGGCCGTGCCATGAGCCGCGCGGCCTTTGAGGGTGTGGTGCGA GCCCTGCTGCAGAAGCCCAGTGCCCGCGTGGCTGTCCTGTTCACCCGTTCTGAGGATGCC CGGGAGCTGCTTGCTGCCAGCCAGCGCCTCAATGCCAGCTTCACCTGGGTGGCCAGTGAT GGTTGGGGGGCCCTGGAGAGTGTGGTGGCAGGCAGTGAGGGGGCTGCTGAGGGTGCTATC ACCATCGAGCTGGCCTCCTACCCCATCAGTGACTTTGCCTCCTACTTCCAGAGCCTGGAC CCTTGGAACAACAGCCGGAACCCCTGGTTCCGTGAATTCTGGGAGCAGAGGTTCCGCTGC AGCTTCCGGCAGCGAGACTGCGCAGCCCACTCTCTCCGGGCTGTGCCCTTTGAGCAGGAG TCCAAGATCATGTTTGTGGTCAATGCAGTGTACGCCATGGCCCATGCGCTCCACAACATG CACCGTGCCCTCTGCCCCAACACCACCCGGCTCTGTGACGCGATGCGGCCAGTTAACGGG CGCCGCCTCTACAAGGACTTTGTGCTCAACGTCAAGTTTGATGCCCCCTTTCGCCCAGCT GACACCCACAATGAGGTCCGCTTTGACCGCTTTGGTGATGGTATTGGCCGCTACAACATC TTCACCTATCTGCGTGCAGGCAGTGGGCGCTATCGCTACCAGAAGGTGGGCTACTGGGCA GAAGGCTTGACTCTGGACACCAGCCTCATCCCATGGGCCTCACCCTCAGCCGGCCCCCTG CCCGCCTCTCGCTGCAGTGAGCCCTGCCTCCAGAATGAGGTGAAGAGTGTGCAGCCGGGC GAAGTCTGCTGCTGGCTCTGCATTCCGTGCCAGCCCTATGAGTACCGATTGGACGAATTC ACTTGCGCTGATTGTGGCCTGGGCTACTGGCCCAATGCCAGCCTGACTGGCTGCTTCGAA CTGCCCCAGGAGTACATCCGCTGGGGCGATGCCTGGGCTGTGGGACCTGTCACCATCGCC TGCCTCGGTGCCCTGGCCACCCTCTTTGTGCTGGGTGTCTTTGTGCGGCACAATGCCACA CCAGTGGTCAAGGCCTCAGGTCGGGAGCTCTGCTACATCCTGCTGGGTGGTGTCTTCCTC TGCTACTGCATGACCTTCATCTTCATTGCCAAGCCATCCACGGCAGTGTGTACCTTACGG CGTCTTGGTTTGGGCACTGCCTTCTCTGTCTGCTACTCAGCCCTGCTCACCAAGACCAAC CGCATTGCACGCATCTTCGGTGGGGCCCGGGAGGGTGCCCAGCGGCCACGCTTCATCAGT CCTGCCTCACAGGTGGCCATCTGCCTGGCACTTATCTCGGGCCAGCTGCTCATCGTGGTC GCCTGGCTGGTGGTGGAGGCACCGGGCACAGGCAAGGAGACAGCCCCCGAACGGCGGGAG GTGGTGACACTGCGCTGCAACCACCGCGATGCAAGTATGTTGGGCTCGCTGGCCTACAAT GTGCTCCTCATCGCGCTCTGCACGCTTTATGCCTTCAAGACTCGCAAGTGCCCCGAAAAC TTCAACGAGGCCAAGTTCATTGGCTTCACCATGTACACCACCTGCATCATCTGGCTGGCA TTCCTGCCCATCTTCTATGTCACCTCCAGTGACTACCGGGTACAGACCACCACCATGTGC GTGTCAGTCAGCCTCAGCGGCTCCGTGGTGCTTGGCTGCCTCTTTGCGCCCAAGCTGCAC ATCATCCTCTTCCAGCCGCAGAAGAACGTGGTTAGCCACCGGGCACCCACCAGCCGCTTT GGCAGTGCTGCTGCCAGGGCCAGCTCCAGCCTTGGCCAAGGGTCTGGCTCCCAGTTTGTC CCCACTGTTTGCAATGGCCGTGAGGTGGTGGACTCGACAACGTCATCGCTTTGAAGACCC CATACTCCCGCCCTGACACAGCTGCTCCTGGGAACCTAGTGCAGACCCACGTCCAGGGCC AGGAGGAAGTTGGCTGGAGCACTGCAATAATTTATTACCCACCCTATGTCTGCCCCCAAA GTCACTTACCCACCTCCTTACCCCAGCTCTTCAGACTCAGAAGTCAGGAGCCTTGGCCAG GAGCCTCTGCAGTGGCCACTAACTGCCCTTGTAGCTGTGTTTCCTCCTGGCCAGGCCCAG GGCTCAGAGAGGAGCAAGCCAGGGTTCACTCTGCCCTGGACCCGGGTGGCTGAGGACGGC AGGCCCCAGTCCTAACCAGCAAAGGTGCTTCCAGCCCAGCCCCTCCCCCCAACTAGGGCC TTTTTTATTTTTTATATAAGT >OriGene 5' read for NM_000839 unedited
GGATTTAGTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGGCTTCGCATCT CTCTTCTTGTCTGTCCTTTCCTGGTCCCTGTTTCCTCCTCTCTTTGCCTTCGCTGCTTCT AATCTCATCCCCTGGAGACCCAGGTCTGCGGGACCCATCCATCCCCTTTGGGGCCATGGG ATCGCTGCTTGCGCTCCTGGCACTGCTGCTGCTGTGGGGTGCTGTGGCTGAGGGCCCAGC CAAGAAGGTGCTGACCCTGGAGGGAGACTTGGTGCTGGGTGGGCTGTTCCCAGTGCACCA GAAGGGCGGCCCAGCAGAGGACTGTGGTCCTGTCAATGAGCACCGTGGCATCCAGCGCCT GGAGGCCATGCTTTTTGCACTGGACCGCATCAACCGTGACCCGCACCTGCTGCCTGGCGT GCGCCTGGGTGCACACATCCTCGACAGTTGCTCCAAGGACACACATGCGCTGGAGCAGGC ACTGGACTTTGTGCGTGCCTCACTCAGCCGTGGTGCTGATGGCTCACGCCACATCTGCCC CGACGGCTCTTATGCGACCCATGGTGATGCTCCCACTGCCATCACTGGTGTTATTGGCGG TTCCTACAGTGATGTCTCCATCCAGGTGGCCAACCTCTTGAGGCTATTTCAGATCCCACA GATTAGCTACGCCTCTACCAGTGCCAAGCTGAGTGACAAGTCCCGCTATGACTACTTTGC CCGCACAGTGCCTCCTGACTTCTTCCCAGCCAAGGCCCTGGCTGAGATTCTCCGCTTCTT CACTGGACCTATGTGTCCACTGTGGCGTCTGAGGCCGACTATGGCGAGACAGGCATTGAG GCCTTTGAGCTAGAGGCTCGTGCCCGCCACATCTGTGTGGCCACCTCCGAAAAAGTGGGC CGTGCCATGACCGCGCGGCCTTTGAGATGTGGTGCGAGCCCTGCTGCAGAAACCCAGTGC CGCGTGGCTGTCCTT >OriGene 3' read for NM_000839 unedited
ATGAACCGCGGCACGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTAAAAAAAAAGCCACTTTTATTTACAGGTAATACAAAATAAACC ACAGGACAAACTACTGGGCAGGGGGAGGGGCACCCCCCAAAATAACCACCCTCCCCATCC CAAAGTAACTTATTTAAAAAATAAAAAAGGCCCTATTTGGGGGGAGGGGCTGGGCTGAAA ACACCTTTGTTGGTTAAAACTGGGGCCTGCCGTCCTAAACCACCCGGGTCCAGGGCAAAG GGAACCCTGGTTTGCTCCTTTTTAACCCCTGGGCCTGGCCAGAAGGAAACACAGCTCCAA GGGCATTTAGGGGCCACTGCAAAGGCTCCTGGCCAAGGCTCCTGACTTTTGATTCTAAAA ACCTGGGGTAAGGAGGGGGGTAATTGACTTTGGGGGCAAACATAGGGGGGGTAATAAATT ATTGAAGGGCTCCAGCCAATTTCCTCCTGGCCCTGAACGTGGGTCTGCACTAGGTTCCCA GAAACACCTGTGTCAGGGCGGAATTATGGGGTCTTAAAAGCGATGACGTTGTCGAGTCCA CCACCTTACGGCCATTGGAAAAGTGGGGAAAACTGGGACCCAACCCTTGGCCAGGGTGGA GCTGCCCTGGCAAAACACTGCAAAAGGGCTGTGGGCGCCCGGGGCTACCCCCGTTTTTTG CGGGTGAAAAGATTAATTCACCTGGGCCCCAAAAGGCCCCATCCCCCGGGGCCCCTTGAG TTTACTGACACCCCCAGGTGGGGGCCCGCCCCGGTTTCTCCCGGAGGGCCATATAAAAGG GCAGATATCCCCCCAAATACCCGGGGGGGCATATCGGAACCAAGAAATTGCCCTCGTGAA TCTTCGGGGCCTGTCGATTCTCAAAGCCTATACTGCAAACCGACAAAGAAACACTTTCCC ACCCACCCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000839 |
| Insert Size | 2619 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000839.2, NP_000830.2 |
| RefSeq Size | 3186 bp |
| RefSeq ORF | 2619 bp |
| Locus ID | 2912 |
| UniProt ID | Q14416 |
| Domains | 7tm_3, ANF_receptor |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218103 | GRM2 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1 |
CNY 3,990.00 |
|
| RC218103L1 | Lenti ORF clone of Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC218103L2 | Lenti ORF clone of Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC218103L3 | Lenti ORF clone of Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC218103L4 | Lenti ORF clone of Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG218103 | GRM2 (tGFP-tagged) - Human glutamate receptor, metabotropic 2 (GRM2), transcript variant 1 |
CNY 4,370.00 |
其它Metabotropic Glutamate Receptor 2产品
