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Cytochrome P450 1A2 (CYP1A2) (NM_000761) Human Untagged Clone
CAT＃: SC119671
CYP1A2 (untagged)-Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2)
CNY 3,848.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CP12; CYPIA2; P3-450; P450(PA) |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000761 edited
GCACCAGGCCATTACAACCCTGCCAATCTCAAGCACCTGCCTCTACAGTTGGTACAGATG GCATTGTCCCAGTCTGTTCCCTTCTCGGCCACAGAGCTTCTCCTGGCCTCTGCCATCTTC TGCCTGGTATTCTGGGTGCTCAAGGGTTTGAGGCCTCGGGTCCCCAAAGGCCTGAAAAGT CCACCAGAGCCATGGGGCTGGCCCTTGCTCGGGCATGTGCTGACCCTGGGGAAGAACCCG CACCTGGCACTGTCAAGGATGAGCCAGCGCTACGGGGACGTCCTGCAGATCCGCATTGGC TCCACGCCCGTGCTGGTGCTGAGCCGCCTGGACACCATCCGGCAGGCCCTGGTGCGGCAG GGCGACGATTTCAAGGGCCGGCCTGACCTCTACACCTCCACCCTCATCACTGATGGCCAG AGCTTGACCTTCAGCACAGACTCTGGACCGGTGTGGGCTGCCCGCCGGCGCCTGGCCCAG AATGCCCTCAACACCTTCTCCATCGCCTCTGACCCAGCTTCCTCATCCTCCTGCTACCTG GAGGAGCATGTGAGCAAGGAGGCTAAGGCCCTGATCAGCAGGTTGCAGGAGCTGATGGCA GGGCCTGGGCACTTCGACCCTTACAATCAGGTGGTGGTGTCAGTGGCCAACGTCATTGGT GCCATGTGCTTCGGACAGCACTTCCCTGAGAGTAGCGATGAGATGCTCAGCCTCGTGAAG AACACTCATGAGTTCGTGGAGACTGCCTCCTCCGGGAACCCCCTGGACTTCTTCCCCATC CTTCGCTACCTGCCTAACCCTGCCCTGCAGAGGTTCAAGGCCTTCAACCAGAGGTTCCTG TGGTTCCTGCAGAAAACAGTCCAGGAGCACTATCAGGACTTTGACAAGAACAGTGTCCGG GACATCACGGGTGCCCTGTTCAAGCACAGCAAGAAGGGGCCTAGAGCCAGCGGCAACCTC ATCCCACAGGAGAAGATTGTCAACCTTGTCAATGACATCTTTGGAGCAGGATTTGACACA GTCACCACAGCCATCTCCTGGAGCCTCATGTACCTTGTGACCAAGCCTGAGATACAGAGG AAGATCCAGAAGGAGCTGGACACTGTGATTGGCAGGGAGCGGCGGCCCCGGCTCTCTGAC AGACCCCAGCTGCCCTACTTGGAGGCCTTCATCCTGGAGACCTTCCGACACTCCTCCTTC TTGCCCTTCACCATCCCCCACAGCACAACAAGGGACACAACGCTGAATGGCTTCTACATC CCCAAGAAATGCTGTGTCTTCGTAAACCAGTGGCAGGTCAACCATGACCCAGAGCTGTGG GAGGACCCCTCTGAGTTCCGGCCTGAGCGGTTCCTCACCGCCGATGGCACTGCCATTAAC AAGCCCTTGAGTGAGAAGATGATGCTGTTTGGCATGGGCAAGCGCCGGTGTATCGGGGAA GTCCTGGCCAAGTGGGAGATCTTCCTCTTCCTGGCCATCCTGCTACAGCAACTGGAGTTC AGCGTGCCGCCGGGCGTGAAAGTCGACCTGACCCCCATCTACGGGCTGACCATGAAGCAC GCCCGCTGTGAACATGTCCAGGCGCGGCTGCGCTTCTCCATCAACTGAAGAAGACACCAC CATTCTGAGGCCAGGGAGCGAGTGGGGGCCAGCCACGGGGACTCAGCCCTTGTTTCTCTT CCTTTCTTTTTTTAAAAAATAGCAGCTTTAGC >OriGene 5' read for NM_000761 unedited
NGTTCAAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGATTACAACCC TGCCAATCTCAAGCACCTGCCTCTACAGTTGGTACAGATGGCATTGTCCCAGTCTGTTCC CTTCTCGGCCACAGAGCTTCTCCTGGCCTCTGCCATCTTCTGCCTGGTATTCTGGGTGCT CAAGGGTTTGAGGCCTCGGGTCCCCAAAGGCCTGAAAAGTCCACCAGAGCCATGGGGCTG GCCCTTGCTCGGGCATGTGCTGACCCTGGGGAAGAACCCGCACCTGGCACTGTCAAGGAT GAGCCAGCGCTACGGGGACGTCCTGCAGATCCGCATTGGCTCCACGCCCGTGCTGGTGCT GAGCCGCCTGGACACCATCCGGCAGGCCCTGGTGCGGCAGGGCGACGATTTCAAGGGCCG GCCTGACCTCTACACCTCCACCCTCATCACTGATGGCCAGAGCTTGACCTTCAGCACAGA CTCTGGACCGGTGTGGGCTGCCCGCCGGCGCCTGGCCCAGAATGCCCTCAACACCTTCTC CATCGCCTCTGACCCAGCTTCCTCATCCTCCTGCTACCTGGAGGAGCATGTGAGCAAGGA GGCTAAGGCCCTGATCAGCAGGTTGCAGGAGCTGATGGCAGGGCCTGGGCACTTCGACCC TTACAATCAGGTGGTGGTGTCAGTGGCCAACGTCATTGGTGCCATGTGCTTCGGACAGCA CTTCCCTGAGAGTAGCGATGAGATGCTCAGCCTCGTGAAGACACTCATGAGTTCGTGGAG ACTGCCTCCTNCGGGAACCCCCTGGACTTCTTCCCCATCCTTCGCTACCTGCCTAACCCT GCCCTGCAGAGGTTCAAGGCCTTTCACCAGAGTTCCCTGTGGTTCCTGCAAANACAGTCC AGGAGCACTATCAGG >OriGene 3' read for NM_000761 unedited
TATCTTGNCCGCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTTTCATTGGGTA ATTCCATTTATATGAAATGTTTAGAGAAGGCAAATCCATAGACACAGAAAGTAGATTAGC AGTTGCCAGGGCTGGTGAGGCAGGGGAGGCAGGCTAGGGGGAAATGTGGAGGGACTGCTA ATGGGTGCAGGGTTTCTTTTAGGGGTGATGAAAATGTTCTAAAATTAATTGTGGGCCGGG CACCGTGGCTCACACCTGTAATGCCAGCACTTTGAGAGAGGTCGAGGCGGGCAGATCACT TGAGGTCAAAAGTTTGAGACTAGTCTAGCCAACATGGTGAAACCCGTCTCTACTAAAAAT ACAAAAATTACCCAGGCGTGGTGGTGTGTGCCTGTAGTCTCAGCTACTTGGGAGGCTGAG GCTGGAGAAGCACTTGAACCTGGGAGGCAAAGGTTGCAGTGAGCTGAGATGATGCCACTG CACTCCAGCTTAGGAGACAGAGGAAGACTCTGTCTCAAAAAAAAAAAAAAACAAAAAGGC TGGGCGCGGTGGTTCATACCTGTTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATC ACGAGGTCAAGAGATGGAGACCATCCTGNCCAACACAGTGAAACCTCGTCTCTACTAAAA AACAAAAATAGCTGGCCATGGTGGCGCATGCCTATAGTCCCAGCTACTTCGGAGGGGCTG AGCAGAGAATCCCTGAACATGNNGAGCGGAGTTGTANTGACCTGAAATCGCGCACTGCAC TCAGCCTGGCAACAGAGTAGACTCTGTCTCAAANNTATAGAAATATAAATTAATTCTGGG ATGGGTGCACAATNCACACTAAAAATCATTCGACCTTAAAATGTAGTTAGGCTGGATGGG NNGGCTACACCTGNATCCAGNACTTTGGAACCAAGCCAGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000761 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000761.3, NP_000752.2 |
| RefSeq Size | 3127 bp |
| RefSeq ORF | 1551 bp |
| Locus ID | 1544 |
| UniProt ID | P05177 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450, Transmembrane |
| Protein Pathways | Caffeine metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tryptophan metabolism |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221636 | CYP1A2 (Myc-DDK-tagged)-Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2) |
CNY 3,840.00 |
|
| RC221636L1 | Lenti ORF clone of Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), Myc-DDK-tagged |
CNY 6,240.00 |
|
| RC221636L2 | Lenti ORF clone of Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), mGFP tagged |
CNY 5,890.00 |
|
| RC221636L3 | Lenti ORF clone of Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221636L4 | Lenti ORF clone of Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), mGFP tagged |
CNY 6,240.00 |
|
| RG221636 | CYP1A2 (tGFP-tagged) - Human cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2) |
CNY 5,440.00 |
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