DMT1 (SLC11A2) (NM_000617) Human Untagged Clone

CAT#: SC119791

SLC11A2 (untagged)-Human solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2), transcript variant 4



  "NM_000617" in other vectors (6)

CNY 4,184.00

CNY 7,220.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit polyclonal SLC11A2 Antibody (Center)
    • 400 ul

CNY 6,314.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms AHMIO1; DCT1; DMT1; NRAMP2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119791 sequence for NM_000617 edited (data generated by NextGen Sequencing)
ATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCTGGAGATCATGGGGAG
TCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCT
GGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAG
GAGTACTCTTGTTTTAGCTTTCGTAAACTCTGGGCTTTCACCGGACCAGGTTTTCTTATG
AGCATTGCCTACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCT
GGATTTAAGTTGCTCTGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGG
CTTGCAGCTAGACTGGGAGTGGTTACTGGGCTGCATCTTGCTGAAGTATGTCACCGTCAG
TATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCTCA
GACATGCAAGAAGTCATTGGCTCAGCCATTGCTATCAATCTTCTGTCTGTAGGAAGAATT
CCTCTGTGGGGTGGCGTTCTCATCACCATTGCAGATACTTTTGTATTTCTCTTCTTGGAC
AAATATGGCTTGCGGAAGCTAGAAGCATTTTTTGGCTTTCTCATCACTATTATGGCCCTC
ACATTTGGATATGAGTATGTTACAGTGAAACCCAGCCAGAGCCAGGTACTCAAGGGCATG
TTCGTACCATCCTGTTCAGGCTGTCGCACTCCACAGATTGAACAGGCTGTGGGCATCGTG
GGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAGTCAAGTCTAGACAG
GTAAACCGGAACAATAAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTTCATTGAATCC
TGCATTGCACTCTTTGTTTCCTTCATCATCAATGTCTTTGTTGTCTCAGTCTTTGCTGAA
GCATTTTTTGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTCCT
CATGCTGGCCTCTTTCCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGT
GTTGTGCTGGGATGTTACTTTGGGCCTGCTGCACTCTACATTTGGGCAGTGGGGATCCTG
GCTGCAGGACAGAGCTCCACCATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGGGA
TTCCTGAACCTAAAGTGGTCACGCTTTGCCCGAGTGGTTCTGACTCGCTCTATTGCCATC
ATCCCCACTCTGCTTGTTGCTGTCTTCCAAGATGTAGAGCATCTAACAGGGATGAATGAC
TTTCTGAATGTTCTACAGAGCTTACAGCTTCCCTTTGCTCTCATACCCATCCTCACATTT
ACGAGCTTGCGGCCAGTAATGAGTGACTTTGCCAATGGACTAGGCTGGCGGATTGCAGGA
GGAATCTTGGTCCTTATCATCTGTTCCATCAATATGTACTTTGTAGTGGTTTATGTCCGG
GACCTAGGGCATGTGGCATTATATGTGGTGGCTGCTGTGGTCAGCGTGGCTTATCTGGGC
TTTGTGTTCTACTTGGGTTGGCAATGTTTGATTGCACTGGGCATGTCCTTCCTGGACTGT
GGGCATACGGTAAGCATCTCTAAAGGCCTGCTGACAGAAGAAGCCACCCGTGGCTACGTT
AAATAA

Clone variation with respect to NM_000617.2
>OriGene 5' read for NM_000617 unedited
TAGACGCTCTGGGATATTTGTNAATCCGNACTTCTACTATAGGGCGGCACGCGCAATTCG
GCACGAGGGCGGAGCTGGTAAGAATCATATTCTAAGAACTCAGCCACTCAGGTATCCACC
ATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCTGGAGATCATGGGGAG
TCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTTCACAGTCCCCT
GGGGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAG
GAGTACTCTTGTTTTAGCTTTCGTAAACTCTGGGCTTTCACCGGACCAGGTTTTCTTATG
AGCATTGCCTACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCT
GGATTTAAGTTGCTCTGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGG
CTTGCAGCTAGACTGGGAGTGGTTACTGGGCTGCATCTTGCTGAAGTATGTCACCGTCAG
TATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCTCA
GACATGCAAGAAGTCATTGGCTCAGCCATTGCTATCAATCTTCTGTCTGTAGGAAGAATT
CCTCTGTGGGGTGGGCGTCTCATCACCATTGCAGATACTTTTGTATTTCTCTTCTTGGAC
AAATATGGCTTGCNGAAGCTAGAAGCATTTTTGGGCTTCTCATCACTATTATGGCCCCTC
ACATTTGGATATGAGTATNGTACAGTGAAACCCAGCCAGAGCCAGGTACTCAAGGGCATG
TTCGTACCATNCCTGTCAGGGCTGTCGCACTCACAAAATGAACAAGCTGGGGGCATCGTG
GGAGCTGGCATCATGCCCACACATGTACC
>OriGene 3' read for NM_000617 unedited
ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTGGAAAAAGAA
ATTTTTTTTTAATTAAAAACCAAGTTTACATACGGGTAAATGGGTACTAAAAGCTCAGTT
GTAACCACTCCTAACACCACTAGCAAAACCTCAAGGGAGCCAAGAGCTCTTCCCTTTTCC
CCTGTTAATTTCCAGTATAATGTAGCAGCACAATTATTTCATGTCACATTTAAAAAGAAC
AAGAACCAATTTATATAAAGTACAATTGTATATCCTTAAACATTCCACATAAACACACTG
TCAAAACTCACTGGATATGCTGGAATTGGAGGACTTAAATTTCTACATATTATTTATTGC
ACCCAGAGTACTGGTTAAAATGCACTTTCTGTGAAGATCAAATGCAATAACGTATGAGGG
TATTTTTAACACTGTGAAGTACACACATAATATTATAAAATGCCATTTAATTGGAAGGAG
TTTTCTATCATTGCAAGTCATAAATGTAACTTTTAAAAGAATACTAGCAGCTTTTACCTA
GGCTCCTAAATGCTTGTAAATCTGAGACTGACTGGACCCACCCAGACCCAGGGCAAAGAT
ACATGTTACCATATCATCTTTATAAAGAATTTTTTTTTTGTCGTCAGTTTGGCCTTTCCT
ACTGCAGCCAGGTGAGAGCTTAAGATGTCAGTCCCCAATATCTTCACAGAGTGCCTTTAT
GACCAGTTTGGAGAATTACGNATGGTAGGGGAAGAAGCANATATGAAAAGGGATGGTTAN
GGGGAATNGTCATTCATAACTCTGTGCTATATTACTTGAGGGGCTAAGAAAAATGTATGG
GCAGTGAACACAGTANTGTACCCTTAAATGCCTATAAAGACCATCATNCAGTCTGCGCTT
TGACTGGGTGCAGTATCANTATAATGCTTTTGGGGCTCAAAA
Restriction Sites NotI-NotI     
ACCN NM_000617
Insert Size 4100 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000617.1, NP_000608.1
RefSeq Size 4103 bp
RefSeq ORF 1686 bp
Locus ID 4891
UniProt ID P49281
Domains Nramp
Protein Families Transmembrane
Protein Pathways Lysosome
Gene Summary This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]
Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region compared to variant 1. The resulting protein (isoform 3) has a shorter and distinct N-terminus compared to isoform 1. Variants 4, 5 and 6 encode isoform 3.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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