Prealbumin (TTR) (NM_000371) Human Untagged Clone
CAT#: SC119937
TTR (untagged)-Human transthyretin (TTR)
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119937 sequence for NM_000371 edited (data generated by NextGen Sequencing)
ATGGCTTCTCATCGTCTGCTCCTCCTCTGCCTTGCTGGACTGGTATTTGTGTCTGAGGCT GGCCCTACGGGCACCGGTGAATCCAAGTGTCCTCTGATGGTCAAAGTTCTAGATGCTGTC CGAGGCAGTCCTGCCATCAATGTGGCCGTGCATGTGTTCAGAAAGGCTGCTGATGACACC TGGGAGCCATTTGCCTCTGGGAAAACCAGTGAGTCTGGAGAGCTGCATGGGCTCACAACT GAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAATCTTACTGGAAG GCACTTGGCATCTCCCCATTCCATGAGCATGCAGAGGTGGTATTCACAGCCAACGACTCC GGCCCCCGCCGCTACACCATTGCCGCCCTGCTGAGCCCCTACTCCTATTCCACCACGGCT GTCGTCACCAATCCCAAGGAATGA Clone variation with respect to NM_000371.3 >OriGene 5' read for NM_000371 unedited
CACGAGGGCAGGATGGCTTCTCATCGTCTGCTCCTCCTCTGCCTTGCTGGACTGGTATTT GTGTCTGAGGCTGGCCCTACGGGCACCGGTGAATCCAAGTGTCCTCTGATGGTCAAAGTT CTAGATGCTGTCCGAGGCAGTCCTGCCATCAATGTGGCCGTGCATGTGTTCAGAAAGGCT GCTGATGACACCTGGGAGCCATTTGCCTCTGGGAAAACCAGTGAGTCTGGAGAGCTGCAT GGGCTCACAACTGAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAA TCTTACTGGAAGGCACTTGGCATCTCCCCATTCCATGAGCATGCAGAGGTGGTATTCACA GCCAACGACTCCGGCCCCCGCCGCTACACCATTGCCGCCCTGCTGAGCCCCTACTCCTAT TCCACCACGGCTGTCGTCACCAATCCCAAGGAATGAGGGACTTCTCCTCCAGTGGACCTG AAGGACGAGGGATGGGATTTCATGTAACCAAGAGTATTCCATTTTTACTAAAGCAGTGTT TTCACCTCATATGCTATGTTAGAAGTCCAGGCAGAGACAATAAAACATTCCTGTGAAAGG CAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGA ACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTT GCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATT >OriGene 3' read for NM_000371 unedited
GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCCTTTCACAGGATGTTTTATTGTCT CTGCCTGGACTTCTAACATAGCATATGAGGTGAAAACACTGCTTTAGTAAAAATGGAATA CTCTTGGTTACATGAAATCCCATCCCTCGTCCTTCAGGTCCACTGGAGGAGAAGTCCCTC ATTCCTTGGGATTGGTGACGACAGCCGTGGTGGAATAGGAGTAGGGGCTCAGCAGGGCGG CAATGGTGTATCGGCGGGGGCCGGAGTCGTTGGCTGTGAATACCACCTCTGCATGCTCAT GGAATGGGGAGATGCCAAGTGCCTTCCAGTAAGATTTGGTGTCTATTTCCACTTTGTATA TCCCTTCTACAAATTCCTCCTCAGTTGTGAGCCCATGCAGCTCTCCAGACTCACTGGTTT TCCCAGAGGCAAATGGCTCCCAGGTGTCATCAGCAGCCTTTCTGAACACATGCACGGCCA CATTGATGGCAGGACTGCCTCGGACAGCATCTAGAACTTTGACCATCAGAGGACACTTGG ATTCACCGGTGCCCGTATGGCCAGCCTCAGACACAAATACCAGTCCAGCAAGGCAGATGA GGAGCAGACGATGAGAAGCCATCCTGCCCTCGTGCCGAATTCGCGGCCGCCCTATAGTGA GTCGTATTACAAAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCTNCCACC GTACACGCCTACCGCCCATTTTGCGTCACGGGGCGGGGTTATTACGACATTTTGGAAAGT CCCCGTGATTTTGGTGCCAACCAACTCCCATGACGTCATGGGGTGAGACTTGGAATCCCG CGAGTCAACCGCTATCACGCCATTGTTGACGCCAAACCGCTCACATGGNATAGCGAGACT ATACCTAAAGTACTGCAGTAGAAGTCCCGTAGTCATGACTGGCTAATGCAGCGGCCTTTA CGTCTGAGTAATAGGGCGACTCGCTT |
Restriction Sites | NotI-NotI |
ACCN | NM_000371 |
Insert Size | 444 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_000371.1, NP_000362.1 |
RefSeq Size | 615 bp |
RefSeq ORF | 444 bp |
Locus ID | 7276 |
UniProt ID | P02766 |
Domains | TR_THY |
Protein Families | ES Cell Differentiation/IPS, Secreted Protein |
Gene Summary | This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017] |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204976 | TTR (Myc-DDK-tagged)-Human transthyretin (TTR) |
CNY 1,200.00 |
|
RC204976L1 | Lenti ORF clone of Human transthyretin (TTR), Myc-DDK-tagged |
CNY 3,600.00 |
|
RC204976L2 | Lenti ORF clone of Human transthyretin (TTR), mGFP tagged |
CNY 5,890.00 |
|
RC204976L3 | Lenti ORF clone of Human transthyretin (TTR), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204976L4 | Lenti ORF clone of Human transthyretin (TTR), mGFP tagged |
CNY 3,600.00 |
|
RG204976 | TTR (tGFP-tagged) - Human transthyretin (TTR) |
CNY 2,800.00 |
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