RPGR (NM_000328) Human Untagged Clone
CAT#: SC119976
RPGR (untagged)-Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A
CNY 5,976.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | COD1; CORDX1; CRD; orf15; PCDX; RP3; RP15; XLRP3 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC119976 sequence for NM_000328 edited (data generated by NextGen Sequencing)
ATGAGGGAGCCGGAAGAGCTGATGCCCGATTCGGGTGCTGTGTTTACATTTGGGAAAAGT AAATTTGCTGAAAATAATCCCGGTAAATTCTGGTTTAAAAATGATGTCCCTGTACATCTT TCATGTGGAGATGAACATTCTGCTGTTGTTACCGGAAATAATAAACTTTACATGTTTGGC AGTAACAACTGGGGTCAGTTAGGATTAGGATCAAAGTCAGCCATCAGCAAGCCAACATGT GTCAAAGCTCTAAAACCTGAAAAAGTGAAATTAGCTGCCTGTGGAAGGAACCACACCCTG GTGTCAACAGAAGGAGGCAATGTATATGCAACTGGTGGAAATAATGAAGGACAGTTGGGG CTTGGTGACACCGAAGAAAGAAACACTTTTCATGTAATTAGCTTTTTTACATCCGAGCAT AAGATTAAGCAGCTGTCTGCTGGATCTAATACTTCAGCTGCCCTAACTGAGGATGGAAGA CTTTTTATGTGGGGTGACAATTCCGAAGGGCAAATTGGTTTAAAAAATGTAAGTAATGTC TGTGTCCCTCAGCAAGTGACCATTGGGAAACCTGTCTCCTGGATCTCTTGTGGATATTAC CATTCAGCTTTTGTAACAACAGATGGTGAGCTATATGTGTTTGGAGAACCTGAGAATGGG AAGTTAGGTCTTCCCAATCAGCTCCTGGGCAATCACAGAACACCCCAGCTGGTGTCTGAA ATTCCGGAGAAGGTGATCCAAGTAGCCTGTGGTGGAGAGCATACTGTGGTTCTCACGGAG AATGCTGTGTATACCTTTGGGCTGGGACAATTTGGTCAGCTGGGTCTTGGCACTTTTCTT TTTGAAACTTCAGAACCCAAAGTCATTGAGAATATTAGGGATCAAACAATAAGTTATATT TCTTGTGGAGAAAATCACACAGCTTTGATAACAGATATCGGCCTTATGTATACTTTTGGA GATGGTCGCCACGGAAAATTAGGACTTGGACTGGAGAATTTTACCAATCACTTCATTCCT ACTTTGTGCTCTAATTTTTTGAGGTTTATAGTTAAATTGGTTGCTTGTGGTGGATGTCAC ATGGTAGTTTTTGCTGCTCCTCATCGTGGTGTGGCAAAAGAAATTGAATTCGATGAAATA AATGATACTTGCTTATCTGTGGCGACTTTTCTGCCGTATAGCAGTTTAACCTCAGGAAAT GTACTGCAGAGGACTCTATCAGCACGTATGCGGCGAAGAGAGAGGGAGAGGTCTCCAGAT TCTTTTTCAATGAGGAGAACACTACCTCCAATAGAAGGGACTCTTGGCCTTTCTGCTTGT TTTCTCCCCAATTCAGTCTTTCCACGATGTTCTGAGAGAAACCTCCAAGAGAGTGTCTTA TCTGAACAGGACCTCATGCAGCCAGAGGAACCAGATTATTTGCTAGATGAAATGACCAAA GAAGCAGAGATAGATAATTCTTCAACTGTAGAAAGCCTTGGAGAAACTACTGATATCTTA AACATGACACACATCATGAGCCTGAATTCCAATGAAAAGTCATTAAAATTATCACCAGTT CAGAAACAAAAGAAACAACAAACAATTGGGGAACTGACGCAGGATACAGCTCTTACTGAA AACGATGATAGTGATGAATATGAAGAAATGTCAGAAATGAAAGAAGGGAAAGCATGTAAA CAACATGTGTCACAAGGGATTTTCATGACGCAGCCAGCTACGACTATCGAAGCATTTTCA GATGAGGAAGTAGAGATCCCAGAGGAGAAGGAAGGAGCAGAGGATTCAAAAGGAAATGGA ATAGAGGAGCAAGAGGTAGAAGCAAATGAGGAAAATGTGAAGGTGCATGGAGGAAGAAAG GAGAAAACAGAGATCCTATCAGATGACCTTACAGACAAAGCAGAGGATCATGAATTTTCT AAAACTGAGGAACTAAAACTAGAAGATGTGGATGAGGAAATTAATGCTGAAAATGTGGAA AGCAAGAAGAAAACTGTGGGAGATGATGAAAGTGTTCCTACAGGTTATCACAGTAAAACA GAAGGAGCAGAAAGAACCAATGATGATAGCTCAGCTGAAACTATTGAAAAGAAAGAAAAA GCCAACCTAGAGGAACGGGCCATTTGTGAGTACAATGAAAACCCAAAAGGATACATGCTT GATGATGCAGATAGCAGTTCATTAGAAATCCTAGAAAACAGTGAAACAACACCAAGCAAA GACATGAAAAAAACAAAGAAGATTTTTCTGTTCAAAAGAGTCCCCTCAATAAATCAAAAG ATTGTCAAGAATAACAATGAGCCGCTCCCAGAGATAAAATCCATAGGAGACCAGATCATT TTAAAAAGTGATAATAAAGATGCCGACCAGAACCACATGAGTCAGAATCATCAGAATATC CCACCAACAAATACAGAGAGAAGATCAAAATCCTGTACAATACTATAA Clone variation with respect to NM_000328.2 >OriGene 5' read for NM_000328 unedited
TGTAGATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGTTTGTTGACT TCCGGGAGCGCGGTTGTAGTTGATCTCCGGAGTTTCGCCATGCGGAACTTGGGGGCTTTC GCGGCCCGCGTCGGTGCGGAGTAGCTGCTTTAGCCCCGACCAAACCGTCCTCTACAGCCT CCTGGCCCCGGCGCAGGCTGCCCGTACTGCCCGTGGCATGAGGGAGCCGGAAGAGCTGAT GCCCGATTCGGGTGCTGTGTTTACATTTGGGAAAAGTAAATTTGCTGAAAATAATCCCGG TAAATTCTGGTTTAAAAATGATGTCCCTGTACATCTTTCATGTGGAGATGAACATTCTGC TGTTGTTACCGGAAATAATAAACTTTACATGTTTGGCAGTAACAACTGGGGTCAGTTAGG ATTAGGATCAAAGTCAGCCATCAGCAAGCCAACATGTGTCAAAGCTCTAAAACCTGAAAA AGTGAAATTAGCTGCCTGTGGAAGGAACCACACCCTGGTGTCAACAGAAGGAGGCAATGT ATATGCAACTGGTGGAAATAATGAAGGACAGCTGGGGCTTGGTGACACCGAAGAAAGACC ACTTTTTATGTAATTAGCTCTTTTACATCCGAGCATAAGATTAAGCAGCTGTCTGCTGGA TCTAATACTTCAGCTGCCCTAACTGATGATGGGAGACTTTTTATGTGGGGTGAACATTCC CAAAGGCCAATTGCTTTAAAAAATGTAAGTCATGTCTTGTGTCCCTTACCAGGGACCATT GGGAAACCTGTCTCCTGNATTCCTTGGGGATATTACCATTCACTTTTGTAACACAGATGG TGAGCTTTTGTGTTTGAAGAACTGAGAATGGAAATTAGGTCTTCCAATCACTTCCTGGCA TCCCAAAACCCCACCTGGGGTTG >OriGene 3' read for NM_000328 unedited
TGGCCGCGGCCGCAATCTAGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTAACAGGGGAAACTGACCAGATATAGTTTATTAAAATATGTTCATTATAAACAA TTTTACCTCAGTTTTGTAAAAATTGTAAATACATCAAAAACTGTTACAGGGTCGAAAAAT TGCAAATATTGCCTTATAAAATTATAAAGAAGTAAAATTGTTTAGTAAAAACTAGGAAAT ATTTTATTTCAATTTTCCACATATAAAAATATATTTTTTATTGCAATACTGAACAGTTAA GGCCACAACACTTTAGGGAGAATTTGAGATACACATATTTTGAAATGACTTGTTAAAAAT ATTAGCATAAATAAATATCAAAACTGGTCACACTTATAGAAGCTGAATAAAACATATTAA GTCTTATATCTTTTAAAGACTACTATCAAAAACTTTACTTCATAAGTTATAACATTTTTC AAGTATACATTACAATACACTTGGGGACTGTGAAAACATAAATATATATTTATAGTATTG GACAGGATTTTGATCTTCTCTCTGTATTTGGGGGGGGGATATTCTGATGATTCTGACTCA TGTGGTTCTGGTCGGCATCTTTATTATCACTTTTTAAAATGATCTGGCCTCCTATGGATT TTATCTCTGGGAGCGGCTCATTGTTATTCTTGACAATCTTTTGATTTATTGAGGGGACTC TTTTGAACAAAAAAATCTCTTTGTTTTTTCATGCCTTTGCTTGGGGGTGTTCACTGTTTC CTAGATTTCTAATGACTGCTATTTGATATCAACATGTTCCCTTGGGTTTTATGGACTCAC AATGGCCGTCCTCTAGTGGCTTTCCTTTTTTAAAAGTTAAGTGACTTTTCATG |
Restriction Sites | NotI-NotI |
ACCN | NM_000328 |
Insert Size | 3240 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000328.2, NP_000319.1 |
RefSeq Size | 3082 bp |
RefSeq ORF | 2448 bp |
Locus ID | 6103 |
UniProt ID | Q92834 |
Domains | RCC1 |
Protein Families | Druggable Genome |
Gene Summary | This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008] Transcript Variant: This variant (A) uses an alternate splice site and contains multiple alternative exons in the 3' coding region, compared to variant C. The resulting isoform (A, also referred to as isoform 1) is shorter and has a distinct C-terminus, compared to isoform C. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC220424 | RPGR (Myc-DDK-tagged)-Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A |
CNY 5,968.00 |
|
RC220424L3 | Lenti ORF clone of Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A, Myc-DDK-tagged |
CNY 7,700.00 |
|
RC220424L4 | Lenti ORF clone of Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A, mGFP tagged |
CNY 7,700.00 |
|
RG220424 | RPGR (tGFP-tagged) - Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A |
CNY 7,568.00 |