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Integrin alpha 6 (ITGA6) (NM_000210) Human Untagged Clone
CAT＃: SC120055
ITGA6 (untagged)-Human integrin, alpha 6 (ITGA6), transcript variant 2
CNY 7,480.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD49f; ITGA6B; VLA-6 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000210 edited
GGGCGGCCCGCGAATTCGGCACCAGGGCCGCTGCAGGTCCCCGCTCCCCTCCCCGTGCGT CCGCCCATGGCCGCCGCCGGGCAGCTGTGCTTGCTCTACCTGTCGGCGGGGCTCCTGTCC CGGCTCGGCGCAGCCTTCAACTTGGACACTCGGGAGGACAACGTGATCCGGAAATATGGA GACCCCGGGAGCCTCTTCGGCTTCTCGCTGGCCATGCACTGGCAACTGCAGCCCGAGGAC AAGCGGCTGTTGCTCGTGGGGGCCCCGCGGGCAGAAGCGCTTCCACTGCAGAGAGCCAAC AGAACGGGAGGGCTGTACAGCTGCGACATCACCGCCCGGGGGCCATGCACGCGGATCGAG TTTGATAACGATGCTGACCCCACGTCAGAAAGCAAGGAAGATCAGTGGATGGGGGTCACC GTCCAGAGCCAAGGTCCAGGGGGCAAGGTCGTGACATGTGCTCACCGATATGAAAAAAGG CAGCATGTTAATACGAAGCAGGAATCCCGAGACATCTTTGGGCGGTGTTATGTCCTGAGT CAGAATCTCAGGATTGAAGACGATATGGATGGGGGAGATTGGAGCTTTTGTGATGGGCGA TTGAGAGGCCATGAGAAATTTGGCTCTTGCCAGCAAGGTGTAGCAGCTACTTTTACTAAA GACTTTCATTACATTGTATTTGGAGCCCCGGGTACTTATAACTGGAAAGGGATTGTTCGT GTAGAGCAAAAGAATAACACTTTTTTTGACATGAACATCTTTGAAGATGGGCCTTATGAA GTTGGTGGAGAGACTGAGCATGATGAAAGTCTCGTTCCTGTTCCTGCTAACAGTTACTTA GGTTTTTCTTTGGACTCAGGGAAAGGTATTGTTTCTAAAGATGAGATCACTTTTGTATCT GGTGCTCCCAGAGCCAATCACAGTGGAGCCGTGGTTTTGCTGAAGAGAGACATGAAGTCT GCACATCTCCTCCCTGAGCACATATTCGATGGAGAAGGTCTGGCCTCTTCATTTGGCTAT GATGTGGCGGTGGTGGACCTCAACAAGGATGGGTGGCAAGATATAGTTATTGGAGCCCCA CAGTATTTTGATAGAGATGGAGAAGTTGGAGGTGCAGTGTATGTCTACATGAACCAGCAA GGCAGATGGAATAATGTGAAGCCAATTCGTCTTAATGGAACCAAAGATTCTATGTTTGGC ATTGCAGTAAAAAATATTGGAGATATTAATCAAGATGGCTACCCAGATATTGCAGTTGGA GCTCCGTATGATGACTTGGGAAAGGTTTTTATCTATCATGGATCTGCAAATGGAATAAAT ACCAAACCAACACAGGTTCTCAAGGGTATATCACCTTATTTTGGATATTCAATTGCTGGA AACATGGACCTTGATCGAAATTCCTACCCTGATGTTGCTGTTGGTTCCCTCTCAGATTCA GTAACTATTTTCAGATCCCGGCCTGTGATTAATATTCAGAAAACCATCACAGTAACTCCT AACAGAATTGACCTCCGCCAGAAAACAGCGTGTGGGGCGCCTAGTGGGATATGCCTCCAG GTTAAATCCTGTTTTGAATATACTGCTAACCCCGCTGGTTATAATCCTTCAATATCAATT GTGGGCACACTTGAAGCTGAAAAAGAAAGAAGAAAATCTGGGCTATCCTCAAGAGTTCAG TTTCGAAACCAAGGTTCTGAGCCCAAATATACTCAAGAACTAACTCTGAAGAGGCAGAAA CAGAAAGTGTGCATGGAGGAAACCCTGTGGCTACAGGATAATATCAGAGATAAACTGCGT CCCATTCCCATAACTGCCTCAGTGGAGATCCAAGAGCCAAGCTCTCGTAGGCGAGTGAAT TCACTTCCAGAAGTTCTTCCAATTCTGAATTCAGATGAACCCAAGACAGCTCATATTGAT GTTCACTTCTTAAAAGAGGGATGTGGAGACGACAATGTATGTAACAGCAACCTTAAACTA GAATATAAATTTTGCACCCGAGAAGGAAATCAAGACAAATTTTCTTATTTACCAATTCAA AAAGGTGTACCAGAACTAGTTCTAAAAGATCAGAAGGATATTGCTTTAGAAATAACAGTG ACAAACAGCCCTTCCAACCCAAGGAATCCCACAAAAGATGGCGATGACGCCCATGAGGCT AAACTGATTGCAACGTTTCCAGACACTTTAACCTATTCTGCATATAGAGAACTGAGGGCT TTCCCTGAGAAACAGTTGAGTTGTGTTGCCAACCAGAATGGCTCGCAAGCTGACTGTGAG CTCGGAAATCCTTTTAAAAGAAATTCAAATGTCACTTTTTATTTGGTTTTAAGTACAACT GAAGTCACCTTTGACACCCCAGATCTGGATATTAATCTGAAGTTAGAAACAACAAGCAAT CAAGATAATTTGGCTCCAATTACAGCTAAAGCAAAAGTGGTTATTGAACTGCTTTTATCG GTCTCGGGAGTTGCTAAACCTTCCCAGGTGTATTTTGGAGGTACAGTTGTTGGCGAGCAA GCTATGAAATCTGAAGATGAAGTGGGAAGTTTAATAGAGTATGAATTCAGGGTAATAAAC TTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAA ATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAG GTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACGGAGTCTCACAACTCA AGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTT GCTGAAAGAAAATACCAGACTCTTAACTGTAGCGTGAACGTGAACTGTGTGAACATCAGA TGCCCGCTGCGGGGGCTGGACAGCAAGGCGTCTCTTATTTTGCGCTCGAGGTTATGGAAC AGCACATTTCTAGAGGAATATTCCAAACTGAACTACTTGGACATTCTCATGCGAGCCTTC ATTGATGTGACTGCTGCTGCCGAAAATATCAGGCTGCCAAATGCAGGCACTCAGGTTCGA GTGACTGTGTTTCCCTCAAAGACTGTAGCTCAGTATTCGGGAGTACCTTGGTGGATCATC CTAGTGGCTATTCTCGCTGGGATCTTGATGCTTGCTTTATTAGTGTTTATACTATGGAAG TGTGGTTTCTTCAAGAGAAATAAGAAAGATCATTATGATGCCACATATCACAAGGCTGAG ATCCATGCTCAGCCATCTGATAAAGAGAGGCTTACTTCTGATGCATAGTATTGATCTACT TCTGTAATTGTGTGGATTCTTTAAACGCTCTAGGTACGATGACAGTGTTCCCCGATACCA TGCTGTAAGGATCCGGAAAGAAGAGCGAGAGATCAAAGATGAAAAGTATATTGATAACCT TGAAAAA >OriGene 5' read for NM_000210 unedited
TGTGCGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACCAGGCCGCT GCAGGTCCCCGCTCCCCTCCCCGTGCGTCCGCCCATGGCCGCCGCCGGGCAGCTGTGCTT GCTCTACCTGTCACTCGGGGCTCCTGTCCCGGCTCGGCGCAGCCTTCAACTTGGACACTC GGGAGGACAACGTGATCCGGAAATATGGAGACCCCGGGAGCCTCTTCGGCTTCTCGCTGG CCATGCACTGGCAACTGCAGCCCGAGGACAAGCGGCTGTTGCTCGTGGGGGCCCCGCGGG CAGAAGCGCTTCCACTGCAGAGAGCCAACAGAACGGGAGGGCTGTACAGCTGCGACACTA CCGCCCGGGGGCTCATGCACGCGGATCGAGTTTGATAACGATGCTGACCCCACGTCAGAA AGCAAGGAAGATCAGTGGATGGGGGTCACCGTCCAGAGCCAAGGTCCAGGGGGCAAGGTC GTGACATGTGCTCACCGATATGAAAAAAGGCAGCATGTTAATACGAAGCAGGAATCCCGA GACATCTTTGGGCGGTGTTATGTCCTGAGTCAGAATCTCAGGATTGAAGACGATATGGAT GGGGGAGATTGGAGCTTTTGTGATGGGCGATTGAGAGGCCATGAGAAATTTGGCTCTTGC CAGCAAGGTGTAACAGCTACTTTTACTAAAGACTTTCATTACATTGTATTTGGAGCCCCG GTACTTACTACTGGAAAGGGATGTTCGTGTAGAGCACAAGAATACCACTTTTTTGCCATG AACATCTTTTGAGATGGGCCTTATGAATTTGGTGGAGAGACTGAGCATGATGAAAGTCTC GGTCCTGTTCCTGCTAACAGTACTTAGGTTTTCCTTGCACTCAGGCAAGGCATTGTTTCT AAAGATGAGACACCTTTTGAATCTGGGGCTCCCAGAACCCATCCAGTGCAGC >OriGene 3' read for NM_000210 unedited
NAACCCCGGGAANAAACCCCCCAACCATCCCCCAAAATNNTTGACTGTGCNCNCCGGCCC GCTATTCTNANGATCGNGTTTTTTTTTTTTTTTTTTTAACTTTTATAAAAAATTATTTCA CACTTTTATACAAATATCCACAGGTAATTTCTAATCATGAAATAATTTTACAATGCTAGT TAGTACAAAAATGTATCAAATGCAAACAGACCAGTGACTTGACTTGAGATGACATTTTTA ACAACCATAAATCTAAACACCATAACATCTTTGTTTCTTTGTTGAACCACCCTCCCAACA CCCTTTTCAGGACATTCATCTTTTTTTTAGCAACACAGGTCTAAAAACACTGTCAAAGTA TCCAGTTCCTTACCAATCTACTAATCTACACCACATTAGGGACACAAGCTCCCCCATCAA GAAACTGACACTTCAAACACTGTTATAACCTGTTTTACCGCACCTCTCGCAAACCATCTA CCTTTCCCGACTAATACTTCTACCCTTCTACCCAAACAACTCCCTTTGCTTCTTACCGCT TTTCATTCCCCGAAATTATAAACCCCTTTCTCACTTACCCCTTGCCTCTCTTCCCGCTCC CCTCCCCTTCCCATGTTCTCCCCCACGTCCTCACCACACCCAATTATTCCCCCCATTATT TCGCCCTTTCCCCCCCACTCCCCCCCCCCTCTTCCCCCCCTTTCCCTCACCCCCCCCCCC CCTTTTCCTCCTATTTTCCCAATTTCCCTCCCTTCCCCTATTTTTCCCCCTCCCTTCCTC CGCTTCCCTTCCCCGATTCCCCTCTTCGTCTCCATCCCTCACCCTCTACCACCTCTTCCA CCACCCCCCTCGCTCTTCACCCACCTATCTTCTCCCTCCCTCCCCCCCTCCTCCCTTCTC CTTCCCCCCTCCCCCTCCCTCCTCCCTTATTTCCCCTTCCCTTTTTTTCCCCTTCTCCTT CGCCCTCCTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000210 |
| Insert Size | 4730 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000210.1, NP_000201.1 |
| RefSeq Size | 5611 bp |
| RefSeq ORF | 3222 bp |
| Locus ID | 3655 |
| UniProt ID | P23229 |
| Domains | FG-GAP |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer |
| Gene Summary | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] Transcript Variant: This variant (2) contains an alternate coding exon compared to variant 1, which results in a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221990 | ITGA6 (Myc-DDK-tagged)-Human integrin, alpha 6 (ITGA6), transcript variant 2 |
CNY 7,472.00 |
|
| RC221990L1 | Lenti ORF clone of Human integrin, alpha 6 (ITGA6), transcript variant 2, Myc-DDK-tagged |
CNY 9,872.00 |
|
| RC221990L2 | Lenti ORF clone of Human integrin, alpha 6 (ITGA6), transcript variant 2, mGFP tagged |
CNY 7,600.00 |
|
| RC221990L3 | Lenti ORF clone of Human integrin, alpha 6 (ITGA6), transcript variant 2, Myc-DDK-tagged |
CNY 7,600.00 |
|
| RC221990L4 | Lenti ORF clone of Human integrin, alpha 6 (ITGA6), transcript variant 2, mGFP tagged |
CNY 9,872.00 |
|
| RG221990 | ITGA6 (tGFP-tagged) - Human integrin, alpha 6 (ITGA6), transcript variant 2 |
CNY 9,072.00 |
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