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Cytochrome P450 2A6 (CYP2A6) (NM_000762) Human Untagged Clone
CAT＃: SC120818
CYP2A6 (untagged)-Human cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6)
CNY 3,656.00
CNY 7,890.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120818 sequence for NM_000762 edited (data generated by NextGen Sequencing)
ATGCTGGCCTCAGGGATGCTTCTGGTGGCCTTGCTGGTCTGCCTGACTGTGATGGTCTTG ATGTCTGTTTGGCAGCAGAGGAAGAGCAAGGGGAAGCTGCCTCCGGGACCCACCCCATTG CCCTTCATTGGAAACTACCTGCAGCTGAACACAGAGCAGATGTACAACTCCCTCATGAAG ATCAGTGAGCGCTATGGCCCCGTGTTCACCATTCACTTGGGGCCCCGGCGGGTCGTGGTG CTGTGTGGACATGATGCCGTCAGGGAGGCTCTGGTGGACCAGGCTGAGGAGTTCAGCGGG CGAGGCGAGCAAGCCACCTTCGACTGGGTCTTCAAAGGCTATGGCGTGGTATTCAGCAAC GGGGAGCGCGCCAAGCAGCTCCGGCGCTTCTCCATCGCCACCCTGCGGGACTTCGGGGTG GGCAAGCGAGGCATCGAGGAGCGCATCCAGGAGGAGGCGGGCTTCCTCATCGACGCCCTC CGGGGCACTGGCGGCGCCAATATCGATCCCACCTTCTTCCTGAGCCGCACAGTCTCCAAT GTCATCAGCTCCATTGTCTTTGGGGACCGCTTTGACTATAAGGACAAAGAGTTCCTGTCA CTGTTGCGCATGATGCTAGGAATCTTCCAGTTCACGTCAACCTCCACGGGGCAGCTCTAT GAGATGTTCTCTTCGGTGATGAAACACCTGCCAGGACCACAGCAACAGGCCTTTCAGTTG CTGCAAGGGCTGGAGGACTTCATAGCCAAGAAGGTGGAGCACAACCAGCGCACGCTGGAT CCCAATTCCCCACGGGACTTCATTGACTCCTTTCTCATCCGCATGCAGGAGGAGGAGAAG AACCCCAACACGGAGTTCTACTTGAAAAACCTGGTGATGACCACGTTGAACCTCTTCATT GGGGGCACCGAGACCGTCAGCACCACCCTGCGCTATGGCTTCTTGCTGCTCATGAAGCAC CCAGAGGTGGAGGCCAAGGTCCATGAGGAGATTGACAGAGTGATCGGCAAGAACCGGCAG CCCAAGTTTGAGGACCGGGCCAAGATGCCCTACATGGAGGCAGTGATCCACGAGATCCAA AGATTTGGAGACGTGATCCCCATGAGTTTGGCCCGCAGAGTCAAAAAGGACACCAAGTTT CGGGATTTCTTCCTCCCTAAGGGCACCGAAGTGTACCCTATGCTGGGCTCTGTGCTGAGA GACCCCAGTTTCTTCTCCAACCCCCAGGACTTCAATCCCCAGCACTTCCTGAATGAGAAG GGGCAGTTTAAGAAGAGTGATGCTTTTGTGCCCTTTTCCATCGGAAAGCGGAACTGTTTC GGAGAAGGCCTGGCCAGAATGGAGCTCTTTCTCTTCTTCACCACCGTCATGCAGAACTTC CGCCTCAAGTCCTCCCAGTCACCTAAGGACATTGACGTGTCCCCCAAACACGTGGGCTTT GCCACGATCCCACGAAACTACACCATGAGCTTCCTGCCCCGCTGA Clone variation with respect to NM_000762.5 51 a=>g >OriGene 5' read for NM_000762 unedited
AGGAATTTGTAATACGACTCACTATAGGCGGCCCGCGAATTCGCACCATCCACCATGCTG GCCTCAGGGATGCTTCTGGTGGCCTTGCTGGTCTGCCTGACTGTGATGGTCTTGATGTCT GTTTGGCAGCAGAGGAAGATCAAGGGGAAGCTGCCTCCGGGACCCACCCCATTGCCCTTC ATTGGAAACTACCTGCAGCTGAACACAGAGCAGATGTACAACTCCCTCATGAAGATCAGT GAGCGCTATGGCCCCGTGTTCACCATTCACTTGGGGCCCCGGCGGGTCGTGGTGCTGTGT GGACATGATGCCGTCAGGGAGGCTCTGGTGGACCATGCTGAAGAGTTCAGCGGGCGATGC GAGCAAGCCACCTTCGACTGGGTCTTCAAAGGCTATGGCGTGGTATTCAGCAACGGGGAG CGCGCCAAGCAGCTCCGGCGCTTCTCCATCGCCACCCTGCGGGACTTCGGGGTGGGCAAG CGAGGCATCGAGGAGCGCATCCAGGATGATGCGGGCTTCCTCATCGACGCCCTCCGGGGC ACTGGCGGCGCCAATATCGATCCCACCTTCTTCCTGAGCCGCACAGTCTCCAATGTCATC AGCTCCATTGTCTTTGGGGACCGCTTTGACTATAAAGACAAAGAGTTCCTGTCACTGTTG CGCATGATGCTAAGAATCTTCCAGTTCACGTCAACCTCCACGGAGCAGCTCTATGAGATG TTCTCTTCGGTGATGAAACACCTGCCATGACCACAGCATCAGGCCTTTCATTTGCTGCAA GGGCTGGATGACTTCATAGCCAAGAATGTGGAGCACAACCAGCGCACGCTGGATCCCANN TCCCACGGNACTCATTGACTCCTTCTATCGCTGCAGGAGGATGATATATCCCACACGNGT TCTACTGAAACCTGTGATGACACGCTGACTCTCATGGGGGCACGAGACGTAGCACACCTG GCTT >OriGene 3' read for NM_000762 unedited
CGGATTGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCT ATGACCTTGGCCGCAATCTAGAGTCGAGTTTTTTTTTGGTTTTTTTTCAGGAAATAAGAG CTGCTATTATTACTACTCTTCATAGCATAATGTAAGGGTTTCCTTCCTCTCATCCCAGCT CGGAAGCACCTTATCAAGGTGAACTGAGCCCCTTCTGTTTCTTCTCTTCCCTCTAGCCAC CACGCCCCTTCCTTTCCCGCATCTTCCCCCCATTCTTATACCCGCCTCTTCCGCGAACCC CGCCCTGACCCCGCCTTTCCCTGGCCCCGCCCACCAGACCTGCACCGGCACAGCCCTCGC TCAGCGGGGCAGGAAGCTCATGGTGTAGTTTCGTGGGATCGTGGCAAAGCCCACGTGTTT GGGGGACACGTCAATGTCCTTAGGTGACTGGGAGGACTTGAGGCGGAAGTTCTGCATGAC GGTGGTGAAGAAGAGAAAGAGCNTCATTCTGCCCAGCCTTCTCGANACAGTTTCGCTTTC CGATGGAAAAGGCACANNAGCATCACTCTTCTTTAACTGCCCCTTCTATTCANGAAGTGC NTGGGATTGAAGTCTTGNGGGTTGAGAAGAAAACTGGGTCTCTCACACAAAAGCCAGCAT TAGGTACACTTCGGTGCCTTTAGGGAAGAAGGATCCCCGAANCTGTGGTTCTTTTGACTC TGCGGGCAAACTCATGGGGTTCACTTTCAATTCTTTGAATCTCGGATCCACTGCTCCGTG G |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000762 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000762.4, NP_000753.2 |
| RefSeq Size | 1751 bp |
| RefSeq ORF | 1485 bp |
| Locus ID | 1548 |
| UniProt ID | P11509 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450, Transmembrane |
| Protein Pathways | Caffeine metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Retinol metabolism |
| Gene Summary | This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222995 | CYP2A6 (Myc-DDK-tagged)-Human cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6) |
CNY 3,656.00 |
|
| RC222995L3 | Lenti ORF clone of Human cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC222995L4 | Lenti ORF clone of Human cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6), mGFP tagged |
CNY 5,890.00 |
|
| RG222995 | CYP2A6 (tGFP-tagged) - Human cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6) |
CNY 5,256.00 |
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