United States
Germany
Japan
United Kingdom
China
IBRDC2 (RNF144B) (NM_182757) Human Untagged Clone
CAT＃: SC121747
RNF144B (untagged)-Human ring finger protein 144B (RNF144B)
CNY 2,400.00
CNY 6,270.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA528A10.3; IBRDC2; p53RFP; PIR2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC121747 sequence for NM_182757 edited (data generated by NextGen Sequencing)
ATGGGCTCAGCTGGTAGGCTCCACTATCTCGCCATGACTGCTGAAAATCCCACTCCTGGA GACCTGGCTCCGGCCCCCCTCATCACTTGCAAACTCTGCCTGTGTGAGCAGTCTCTGGAC AAGATGACCACACTCCAGGAATGCCAGTGCATCTTTTGCACAGCTTGCCTGAAACAGTAC ATGCAGCTGGCAATCCGAGAAGGATGTGGGTCTCCCATCACTTGCCCTGACATGGTGTGC CTAAACCACGGGACCCTGCAGGAAGCTGAGATTGCCTGTTTGGTACCTGTGGACCAGTTT CAACTTTATCAGAGGTTAAAATTTGAAAGAGAAGTTCATCTGGACCCCTACCGAACATGG TGTCCTGTTGCAGACTGTCAGACAGTGTGCCCTGTTGCCTCGAGTGACCCAGGACAGCCT GTGCTGGTGGAATGCCCTTCTTGCCACCTGAAATTCTGCTCGTGTTGCAAGGATGCTTGG CATGCAGAGGTCTCCTGTAGAGACAGTCAGCCTATTGTCCTGCCAACAGAGCACCGAGCC CTCTTTGGGACAGATGCAGAAGCCCCCATTAAGCAGTGCCCAGTTTGCCGGGTTTATATC GAACGCAATGAAGGCTGCGCTCAGATGATGTGCAAAAACTGCAAGCATACATTTTGCTGG TACTGCCTCCAGAACTTGGATAATGACATTTTCCTCAGACATTATGACAAAGGGCCATGC AGGAATAAACTTGGCCACTCAAGAGCATCAGTGATGTGGAACCGAACACAGGTGGTGGGG ATTCTCGTAGGCTTGGGCATCATTGCCTTGGTTACTTCACCCTTGTTACTCCTGGCCTCC CCATGTATAATCTGTTGTGTCTGCAAGTCCTGTCGGGGCAAGAAGAAAAAGCACGACCCA TCCACAACCTAA Clone variation with respect to NM_182757.3 >OriGene 5' read for NM_182757 unedited
GCCGCGAATTCGGCACGAGCAGAGCACGGAGGAAAGACGGAGAGAATGGAAGAGCTCCTG TCCGGTGTGCCAGCAGCCCGGACTGGCGGTGAGCGCGAGGGAGGCTACTGAGAAGCCCGG CGACGGAGGAACGCAGGTCTGCTGCCAGGGATTGAGGAGACTGAAGAACGCTGAAGACAG GCTGATGGGCTCAGCTGGTAGGCTCCACTATCTCGCCATGACTGCTGAAAATCCCACTCC TGGAGACCTGGCTCCGGCCCCCCTCATCACTTGCAAACTCTGCCTGTGTGAGCAGTCTCT GGACAAGATGACCACACTCCAGGAATGCCAGTGCATCTTTTGCACAGCTTGCCTGAAACA GTACATGCAGCTGGCAATCCGAGAAGGATGTGGGTCTCCCATCACTTGCCCTGACATGGT GTGCCTAAACCACGGGACCCTGCAGGAAGCTGAGATTGCCTGTTTGGTACCTGTGGACCA GTTTCAACTTTATCAGAGGTTAAAATTTGAAAGAGAAGTTCATCTGGACCCCTACCGAAC ATGGTGTCCTGTTGCAGACTGTCAGACAGTGTGCCCTGTTGCCTCGAGTGACCCAGGACA GCCTGTGCTGGTGGAATGCCCTTCTTGCCACCTGAAATTCTGCTCGTGTTGCAAGGATGC TTGGCATGCANAGGTCTNCTGTANAGACAGTCAGCCTATTGTCCTGCCACAGAGCACCGA GCCCTCTTTGGGACAGATGCAGAAGCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_182757 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_182757.2, NP_877434.2 |
| RefSeq Size | 4782 bp |
| RefSeq ORF | 912 bp |
| Locus ID | 255488 |
| UniProt ID | Q7Z419 |
| Protein Families | Transmembrane |
| Gene Summary | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209302 | RNF144B (Myc-DDK-tagged)-Human ring finger protein 144B (RNF144B) |
CNY 2,400.00 |
|
| RC209302L1 | Lenti ORF clone of Human ring finger protein 144B (RNF144B), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC209302L2 | Lenti ORF clone of Human ring finger protein 144B (RNF144B), mGFP tagged |
CNY 17,860.00 |
|
| RC209302L3 | Lenti ORF clone of Human ring finger protein 144B (RNF144B), Myc-DDK-tagged |
CNY 17,860.00 |
|
| RC209302L4 | Lenti ORF clone of Human ring finger protein 144B (RNF144B), mGFP tagged |
CNY 17,860.00 |
|
| RG209302 | RNF144B (tGFP-tagged) - Human ring finger protein 144B (RNF144B) |
CNY 4,000.00 |
