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KCNK10 (NM_138317) Human Untagged Clone
CAT＃: SC121923
KCNK10 (untagged)-Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2
CNY 4,048.00
CNY 8,740.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | K2p10.1; PPP1R97; TREK-2; TREK2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_138317, the custom clone sequence may differ by one or more nucleotides
ATGAAATTTCCAATCGAGACGCCAAGAAAACAGGTGAACTGGGATCCTAAAGTGGCCGTTCCCGCAGCAG CACCGGTGTGCCAGCCCAAGAGCGCCACTAACGGGCAACCCCCGGCTCCGGCTCCGACTCCAACTCCGCG CCTGTCCATTTCCTCCCGAGCCACAGTGGTAGCCAGGATGGAAGGCACCTCCCAAGGGGGCTTGCAGACC GTCATGAAGTGGAAGACGGTGGTTGCCATCTTTGTGGTTGTGGTGGTCTACCTTGTCACTGGCGGTCTTG TCTTCCGGGCATTGGAGCAGCCCTTTGAGAGCAGCCAGAAGAATACCATCGCCTTGGAGAAGGCGGAATT CCTGCGGGATCATGTCTGTGTGAGCCCCCAGGAGCTGGAGACGTTGATCCAGCATGCTCTTGATGCTGAC AATGCGGGAGTCAGTCCAATAGGAAACTCTTCCAACAACAGCAGCCACTGGGACCTCGGCAGTGCCTTTT TCTTTGCTGGAACTGTCATTACGACCATAGGGTATGGGAATATTGCTCCGAGCACTGAAGGAGGCAAAAT CTTTTGTATTTTATATGCCATCTTTGGAATTCCACTCTTTGGTTTCTTATTGGCTGGAATTGGAGACCAA CTTGGAACCATCTTTGGGAAAAGCATTGCAAGAGTGGAGAAGGTCTTTCGAAAAAAGCAAGTGAGTCAGA CCAAGATCCGGGTCATCTCAACCATCCTGTTCATCTTGGCCGGCTGCATTGTGTTTGTGACGATCCCTGC TGTCATCTTTAAGTACATCGAGGGCTGGACGGCCTTGGAGTCCATTTACTTTGTGGTGGTCACTCTGACC ACGGTGGGCTTTGGTGATTTTGTGGCAGGGGGAAACGCTGGCATCAATTATCGGGAGTGGTATAAGCCCC TAGTGTGGTTTTGGATCCTTGTTGGCCTTGCCTACTTTGCAGCTGTCCTCAGTATGATCGGAGATTGGCT ACGGGTTCTGTCCAAAAAGACAAAAGAAGAGGTGGGTGAAATCAAGGCCCATGCGGCAGAGTGGAAGGCC AATGTCACGGCTGAGTTCCGGGAGACACGGCGAAGGCTCAGCGTGGAGATCCACGATAAGCTGCAGCGGG CGGCCACCATCCGCAGCATGGAGCGCCGGCGGCTGGGCCTGGACCAGCGGGCCCACTCACTGGACATGCT GTCCCCCGAGAAGCGCTCTGTCTTTGCTGCCCTGGACACCGGCCGCTTCAAGGCCTCATCCCAGGAGAGC ATCAACAACCGGCCCAACAACCTGCGCCTGAAGGGGCCGGAGCAGCTGAACAAGCATGGGCAGGGTGCGT CCGAGGACAACATCATCAACAAGTTCGGGTCCACCTCCAGACTCACCAAGAGGAAAAACAAGGACCTCAA AAAGACCTTGCCCGAGGACGTTCAGAAAATCTACAAGACCTTCCGGAATTACTCCCTGGACGAGGAGAAG AAAGAGGAGGAGACGGAAAAGATGTGTAACTCAGACAACTCCAGCACAGCCATGCTGACGGACTGTATCC AGCAGCACGCTGAGTTGGAGAACGGAATGATACCCACGGACACCAAAGACCGGGAGCCGGAGAACAACTC ATTACTTGAAGACAGAAACTAA >OriGene 5' read for NM_138317 unedited
GAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCAGTGGGCTTCTCCG TAGCCCCAGCCTTCAGGCTGCGCAGCCCCTAACCTGCCGGCACCGCTTTTGGGAAGCAGC TTGGCTCTTCCATCTCCCCAAGCCTTCCTCTCCATCCTTTCATCCACCCCTCGCCGATCT TACTTTTTCTTTTACCCACGGGGCCGCGGCCGGCCACCCCCTGGCCGGTGCANACACCCA AGCCCTCTCCAGTTCTCCCCCAAGCTAATATTTTCCCACCTGTCTTTTTCTGGGGTTCCT CCCCGAACCAATCCCAGGCTTCCCCATCCTCGGAAAATGGTTTGGTGGACTGGCTAACCG AAGCGTGGAAAGCTTGGAGACCTTATTAATAATTGGGGTCCTTTCAATTCTTCCCCTTTT GGGCAACGAAACCATTGAAATTTCCAATCGAGACGCCCAAGAAACAAGTGAACTGGGATC CCTAAGTGGCCGTTCCCGGCACAGCACCGGTGTTGCCAGCCCCAAGAGCGCCACTAACGG GCAACCCCCGGGCTCCGGCTCCGACTCCAAACTCCGCGCCCTGTCCATTTCCCTCCCGAG CCCACAGTGGTAGCCCAGGATGGAAGGCACCCTNCCCAAGGGGGCTTGCAGAACCGTCAT GGAAGTGGGAAGAACGGTGGTTGCCATCCTTTGTGGTTGTGGTGGTCTACCTTGTCACTG GCGGTCTTTGTCTTCCGGCATTGGANCAGCCCTTTGAAAGCAGCCCGAAGAATACCTTCC GCCTTGGAGAAGAGCGGAATTTCCGCGGGAAACGT >OriGene 3' read for NM_138317 unedited
CAACTCAACGTGCTGCTGGATACAGTCCGTCAGCATGGCTGTGCTGGAGTTGNNTGAGTT ACACATCTTTTCCGTCTCCTCCTCTTTCTTCTCCTCGTCCAGGGAGTAATTCCGGAAGGT CTTGTAGATTTTCTGAACGTCCTCGGGCAAGGTCTTTTTGAGGTCCTTGTTTTTCCTCTT GGTGAGTCTGGAGGTGGACCCGAACTTGTTGATGATGTTGTCCTCGGACGCACCCTGCCC ATGCTTGTTCAGCTGCTCCGGCCCCTTCAGGCGCAGGTTGTTGGGCCGGTTGTTGATGCT CTCCTGGGATGAGGCCTTGAAGCGGCCGGTGTCCAGGGCAGCAAAGACAGAGCGCTTCTC GGGGGACAGCATGTCCAGTGAGTGGGCCCGCTGGTCCAGGCCCAGCCGCCGGCGCTCCAT GCTGCGGATGGTGGCCGCCCGCTGCAGCTTATCGTGGATCTCCACGCTGAGCCTTCGCCG TGTCTCCCGGAACTCAGCCGTGACATTGGCCTTCCACTCTGCCGCATGGGCCTTGATTTC ACCCACCTCTTCTTTTGTCTTTTTGGACAGAACCCGTAGCCAATCTCCGATCATACTGAG GACAGCTGCAAAGTAGGCAAGGCCAACAAGGATCCAAAACCACACTAGGNGCTTATACCA CTCCCGATAATTGATGCCAGCGTTTCCCCTTGCCACAAATCACCAAAGCCCACCGTGGTC AGAGTGACCACCACANAATAAATTGACTTCAAAGCCGTCCAGGCCCTCATGTACTTAAGA TGACCACCGGTTCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138317 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138317.1, NP_612190.1 |
| RefSeq Size | 2484 bp |
| RefSeq ORF | 1632 bp |
| Locus ID | 54207 |
| UniProt ID | P57789 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008] Transcript Variant: This variant (2, also known as TREK2 splice variant c) has a different 5' terminal exon compared to transcript variant 1, and encodes a slightly longer isoform (2) with a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
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Block of TREK and TRESK K2P channels by lamotrigine and two derivatives sipatrigine and CEN-092
,Walsh, Y;Leach, M;Veale, EL;Mathie, A;,
Biochemistry and biophysics reports
,PubMed ID 34041373
[KCNK10]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223229 | KCNK10 (Myc-DDK-tagged)-Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2 |
CNY 4,040.00 |
|
| RC223229L1 | Lenti ORF clone of Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2, Myc-DDK-tagged |
CNY 6,440.00 |
|
| RC223229L2 | Lenti ORF clone of Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC223229L3 | Lenti ORF clone of Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223229L4 | Lenti ORF clone of Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG223229 | KCNK10 (tGFP-tagged) - Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 2 |
CNY 5,640.00 |
