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KCNA1 (NM_000217) Human Untagged Clone
CAT＃: SC122128
KCNA1 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC122128 representing NM_000217.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGACGGTGATGTCTGGGGAGAACGTGGACGAGGCTTCGGCCGCCCCGGGCCACCCCCAGGATGGCAGC TACCCCCGGCAGGCCGACCACGACGACCACGAGTGCTGCGAGCGCGTGGTGATCAACATCTCCGGGCTG CGCTTCGAGACGCAGCTCAAGACCCTGGCGCAGTTCCCCAACACGCTGCTGGGCAACCCTAAGAAACGC ATGCGCTACTTCGACCCCCTGAGGAACGAGTACTTCTTCGACCGCAACCGGCCCAGCTTCGACGCCATC CTCTACTACTACCAGTCCGGCGGCCGCCTGCGGAGGCCGGTCAACGTGCCCCTGGACATGTTCTCCGAG GAGATCAAGTTTTACGAGTTGGGCGAGGAGGCCATGGAGAAGTTCCGGGAGGACGAGGGCTTCATCAAG GAGGAGGAGCGCCCTCTGCCCGAGAAGGAGTACCAGCGCCAGGTGTGGCTGCTCTTCGAGTACCCCGAG AGCTCGGGGCCCGCCAGGGTCATCGCCATCGTCTCCGTCATGGTCATCCTCATCTCCATCGTCATCTTT TGCCTGGAGACGCTCCCCGAGCTGAAGGATGACAAGGACTTCACGGGCACCGTCCACCGCATCGACAAC ACCACGGTCATCTACAATTCCAACATCTTCACAGACCCCTTCTTCATCGTGGAAACGCTGTGCATCATC TGGTTCTCCTTCGAGCTGGTGGTGCGCTTCTTCGCCTGCCCCAGCAAGACGGACTTCTTCAAAAACATC ATGAACTTCATAGACATTGTGGCCATCATTCCTTATTTCATCACCCTGGGCACCGAGATAGCTGAGCAG GAAGGAAACCAGAAGGGCGAGCAGGCCACCTCCCTGGCCATCCTCAGGGTCATCCGCTTGGTAAGGGTT TTTAGAATCTTCAAGCTCTCCCGCCACTCTAAGGGCCTCCAGATCCTGGGCCAGACCCTCAAAGCTAGT ATGAGAGAGCTAGGGCTGCTCATCTTTTTCCTCTTCATCGGGGTCATCCTGTTTTCTAGTGCAGTGTAC TTTGCCGAGGCGGAAGAAGCTGAGTCGCACTTCTCCAGTATCCCCGATGCTTTCTGGTGGGCGGTGGTG TCCATGACCACTGTAGGATACGGTGACATGTACCCTGTGACAATTGGAGGCAAGATCGTGGGCTCCTTG TGTGCCATCGCTGGTGTGCTAACAATTGCCCTGCCCGTACCTGTCATTGTGTCCAATTTCAACTATTTC TACCACCGAGAAACTGAGGGGGAAGAGCAGGCTCAGTTGCTCCACGTCAGTTCCCCTAACTTAGCCTCT GACAGTGACCTCAGTCGCCGCAGTTCCTCTACTATGAGCAAGTCTGAGTACATGGAGATCGAAGAGGAT ATGAATAATAGCATAGCCCATTATAGACAGGTCAATATCAGAACTGCCAATTGCACCACAGCTAACCAA AACTGCGTTAATAAGAGCAAGCTACTGACCAAAGGGCGA >OriGene 5' read for NM_000217 unedited
GTTTTCATTTGTATACGACTCCTATAGGCGGCACGCGATTCGCCCTTATGACGGTGATGT CTGGGGAGAACGTGGACGAGGCTTCGGCCGCCCCGGGCCACCCCCAGGATGGCAGCTACC CCCGGCAGGCCGACCACGACGACCACGAGTGCTGCGAGCGCGTGGTGATCAACATCTCCG GGCTGCGCTTCGAGACGCAGCTCAAGACCCTGGCGCAGTTCCCCAACACGCTGCTGGGCA ACCCTAAGAAACGCATGCGCTACTTCGACCCCCTGAGGAACGAGTACTTCTTCGACNCGC AACCGGCCCAGCTTCGACGCCATCCTCTACTACTACCAGTCCGGCGGCCGCCTGCGGAGG CCGGTCAACGTGCCCCTGGACATGTTCTCCGAGGAGATCAAGTTTTACGAGTTGGGCGAG GAGGCCATGGAGAAGTTCCGGGAGGACGAGGGCTTCATCAAGGAGGAGGAGCGCCCTCTG CCCGAGAAGGAGTACCAGCGCCAGGTGTGGCTGCTCTTCGAGTACCCCGAGAGCTCGGGG CCCGCCAGGGTCATCGCCATCGTCTCCGTCATGGTCATCCTCATCTCCATCGTCATCTTT TGCCTGGAGACGCTCCCCGAGCTGAAGGATGACAAGGACTTCACGGGCACCGTCCACCGC ATCGACAACACCACGGTCATCTACAATTCCAACATCTTCACAGACCCCTTCTTCATCGTG GAAACGCTGTGCATCATCTGGTTCTCCTTCGAGCTGGTGGTGCGCTTCTTCGCCTGCCCC AGCAGACAGACTTCTTCAAAACATCATGAACTTCATAGACATTGTGGCCATCATTCCTTA TTTCATCACCCTGGGCACCGAGATAGCTGAGCAGGAAGGAAACCAGATGGCGAGCAGGCC ACTNCCTGCCATCCTCAGGNTCATCGCTGGTAAGGNCTTTTAAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_000217 |
| Insert Size | 1488 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000217.1 |
| RefSeq Size | 1488 bp |
| RefSeq ORF | 1488 bp |
| Locus ID | 3736 |
| UniProt ID | Q09470 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| MW | 56.6 kDa |
| Gene Summary | This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211000 | KCNA1 (Myc-DDK-tagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1) |
CNY 3,656.00 |
|
| RC211000L1 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC211000L2 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), mGFP tagged |
CNY 5,890.00 |
|
| RC211000L3 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC211000L4 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), mGFP tagged |
CNY 6,056.00 |
|
| RG211000 | KCNA1 (tGFP-tagged) - Human potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1) |
CNY 5,256.00 |
