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VASP (NM_003370) Human Untagged Clone
CAT＃: SC122656
VASP (untagged)-Human vasodilator-stimulated phosphoprotein (VASP)
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003370 edited
GCAAGGGGTGCGCGCTGGGGAGCGGACGCTGCATCCCCTTTCTGCTGCAGGAACCTCTCA TCAGACCGCCTGAGGGAAGCGGCGCCCGGAGACCCGCCCCGGCCCGGTCCACATTCTCCC CAGGAAGCCGGACTCTATGGGGCGGGACCCTGGGGGAGCCTGAGCCGAGCCCGGAGCCAG CCCCGAACCCCTGAACCTCCAGCCAGGGGCGCCCCGGGAGCAGCCAGCCCGTGGGCGAGC CGCCCGCCCGCCGAGCAGCCATGAGCGAGACGGTCATCTGTTCCAGCCGGGCCACTGTGA TGCTTTATGATGATGGCAACAAGCGATGGCTCCCTGCTGGCACGGGTCCCCAGGCCTTCA GCCGCGTCCAGATCTACCACAACCCCACGGCCAATTCCTTTCGCGTCGTGGGCCGGAAGA TGCAGCCCGACCAGCAGGTGGTCATCAACTGTGCCATCGTCCGGGGTGTCAAGTATAACC AGGCCACCCCCAACTTCCATCAGTGGCGCGACGCTCGCCAGGTCTGGGGCCTCAACTTCG GCAGCAAGGAGGATGCGGCCCAGTTTGCCGCCGGCATGGCCAGTGCCCTAGAGGCGTTGG AAGGAGGTGGGCCCCCTCCACCCCCAGCACTTCCCACCTGGTCGGTCCCGAACGGCCCCT CCCCGGAGGAGGTGGAGCAGCAGAAAAGGCAGCAGCCCGGCCCGTCGGAGCACATAGAGC GCCGGGTCTCCAATGCAGGAGGCCCACCTGCTCCCCCCGCTGGGGGTCCACCCCCACCAC CAGGACCTCCCCCTCCTCCAGGTCCCCCCCCACCCCCAGGTTTGCCCCCTTCGGGGGTCC CAGCTGCAGCGCACGGAGCAGGGGGAGGACCACCCCCTGCACCCCCTCTCCCGGCAGCAC AGGGCCCTGGTGGTGGGGGAGCTGGGGCCCCAGGCCTGGCCGCAGCTATTGCTGGAGCCA AACTCAGGAAAGTCAGCAAGCAGGAGGAGGCCTCAGGGGGGCCCACAGCCCCCAAAGCTG AGAGTGGTCGAAGCGGAGGTGGGGGACTCATGGAAGAGATGAACGCCATGCTGGCCCGGA GAAGGAAAGCCACGCAAGTTGGGGAGAAAACCCCCAAGGATGAATCTGCCAATCAGGAGG AGCCAGAGGCCAGAGTCCCGGCCCAGAGTGAATCTGTGCGGAGACCCTGGGAGAAGAACA GCACAACCTTGCCAAGGATGAAGTCGTCTTCTTCGGTGACCACTTCCGAGACCCAACCCT GCACGCCCAGCTCCAGTGATTACTCGGACCTACAGAGGGTGAAACAGGAGCTTCTGGAAG AGGTGAAGAAGGAATTGCAGAAAGTGAAAGAGGAAATCATTGAAGCCTTCGTCCAGGAGC TGAGGAAGCGGGGTTCTCCCTGACCACAGGGACCCAGAAGACCCGCTTCTCCTTTCCGCA CACCCGGCCTGTCACCCTGCTTTCCCTGCCTCTACTTGACTTGGAATTGGCTGAAGACTA CACAGGAATGCATCGTTCCCACTCCCCATCCCACTTGGAAAACTCCAAGGGGGTGTGGCT TCCCTGCTCACACCCACACTGGCTGCTGATTGGCTGGGGAGGCCCCCGCCCTTTTCTCCC TTTGGTCCTTCCCCTCTGCCATCCCCTTGGGGCCGGTCCCTCTGCTGGGGATGCACCAAT GAACCCCACAGGAAGGGGGAAGGAAGGAGGGAATTTCACATTCCCTTGTTCTAGATTCAC TTTAACGCTTAATGCCTTCAAAGTTTTGGTTTTTTTAAGAAAAAAAAATATATATATATT TGGGTTTTGGGGGAAAAGGGAAATTTTTTTTTCTCTTTGGTTTTGATAAAATGGGATGTG GGAGTTTTTAAATGCTATAGCCCTGGGCTTGCCCCATTTGGGGCAGCTATTTAAGGGGAG GGGATGTCTCACCGGGCTGGGGGTGAGACATCCCCCCACCCCAGGGACTCCCCTTCCCTC TGGCTCCTTCCCCTTTTCTATGAGGAAATAAGATGCTGTAACTTTTTGGAACCTCAGTTT TTTGATTTTTTATTTGGGTAGGTTTTGGGGTCCAGGCCATTTTTTTTACCCCTTGGAGGA AATAAGATGAGGGAGAAAGGAAAAGGGGAGGAAACTTCTCCCCTCCCACCTTCACCTTTA GCTTCTTGAAAATGGGCCCCTGCAGAATAAATCTGCCAGTTTTTATAAAAAAAAAAAAAA AAAAAAAAAAA >OriGene 5' read for NM_003370 unedited
TTCGCATTAGTAATACGACTTACTATAGGGCGGCCGCGATTCCCGGATGCAAGGGTGCGC GCTGGGGAGCGGACGCTGCATCCCCTTTCTGCTGCAGGAACCTCTCATCAGACCGCCTGA GGGAAGCGGCGCCCGGAGACCCGCCCCGGCCCGGTCCACATTCTCCCCAGGAAGCCGGAC TCTATGGGGCGGGACCCTGGGGGAGCCTGAGCCGAGCCCGGAGCCAGCCCCGAACCCCTG AACCTCCAGCCAGGGGCGCCCCGGGAGCAGCCAGCCCGTGGGCGAGCCGCCCGCCCGCCG AGCAGCCATGAGCGAGACGGTCATCTGTTCCAGCCGGGCCACTGTGATGCTTTATGATGA TGGCAACAAGCGATGGCTCCCTGCTGGCACGGGTCCCCAGGCCTTCAGCCGCGTCCAGAT CTACCACAACCCCACGGCCAATTCCTTTCGCGTCGTGGGCCGGAAGATGCAGCCCGACCA GCAGGTGGTCATCAACTGTGCCATCGTCCGGGGTGTCAAGTATAACCAGGCCACCCCCAA CTTCCATCAGTGGCGCGACGCTCGCCAGGTCTGGGGCCTCAACTTCGGCAGCAAGGAGGA TGCGGCCCATTTTGCCGCCGGCATGGCCAGTGCCCTATAGGCGTTGGAAGGATGTGGGCC CCCTCCACCCCCAGCACTTCCCACCTGGTCGGTCCCGAACGGCCCCTCCCCGGANGATGT GGAGCAGCAGAAAGGCAGCAGCCCGGCCCGTCNGAGCACATAGAGCGCCGGGGTCTCAAT GCTATGAGCCCACCTGCTCCCCCCGCTGGGGGTCCACCCCCACCACCAGTACCTCCCCCT TCTCCAAGTTCCCCCCCACCCCCAGTTTGCCCCCTTCGGGGTTCCAACTGCAGCGCACGG GCAGGGGGAGGACCACCCCTGGCCCCCCTT |
| Restriction Sites | Please inquire |
| ACCN | NM_003370 |
| Insert Size | 2231 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003370.3, NP_003361.1 |
| RefSeq Size | 2298 bp |
| RefSeq ORF | 1143 bp |
| Locus ID | 7408 |
| UniProt ID | P50552 |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration |
| Gene Summary | Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury
,Janek Henes, Marthe A. Schmit, Julio C. Morote-Garcia, Valbona Mirakaj, David Köhler, Louise Glover, Therese Eldh, Ulrich Walter, Jörn Karhausen, Sean P. Colgan, and Peter Rosenberger,
FASEB J, Aug 2009; 10.1096/fj.09-138693
[VASP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203544 | VASP (Myc-DDK-tagged)-Human vasodilator-stimulated phosphoprotein (VASP) |
CNY 5,488.00 |
|
| RC203544L1 | Lenti-ORF clone of VASP (Myc-DDK-tagged)-Human vasodilator-stimulated phosphoprotein (VASP) |
CNY 7,888.00 |
|
| RC203544L2 | Lenti-ORF clone of VASP (mGFP-tagged)-Human vasodilator-stimulated phosphoprotein (VASP) |
CNY 5,890.00 |
|
| RC203544L3 | Lenti-ORF clone of VASP (Myc-DDK-tagged)-Human vasodilator-stimulated phosphoprotein (VASP) |
CNY 7,888.00 |
|
| RC203544L4 | Lenti-ORF clone of VASP (mGFP-tagged)-Human vasodilator-stimulated phosphoprotein (VASP) |
CNY 5,890.00 |
|
| RG203544 | VASP (tGFP-tagged) - Human vasodilator-stimulated phosphoprotein (VASP) |
CNY 7,088.00 |
