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TMEM16A (ANO1) (BC033036) Human Untagged Clone
CAT＃: SC123484
ANO1 (untagged)-Human transmembrane protein 16A (cDNA clone MGC:33580 IMAGE:4823645), complete cds
CNY 6,152.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (4)
ANO1 mouse monoclonal antibody, clone OTI1C8 (formerly 1C8)
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | anoctamin 1, calcium activated chloride; FLJ10261; membrane protein; oral cancer overexpressed 2; ORAOV2; TAOS2; TMEM16A; transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor amplified and overexpressed sequence 2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for BC033036 edited
AGCGGGGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCGGC ACCAAATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCC TAGGGCCAGAGAGGCCAAGGTGCCAGGGACATGGCCCCAACTGTCCCCTAACCAGGGGTA GAGGAGTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTGGA CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTA CATCCTGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCCTGGTCAGGAGGGTGCA GCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA GGGGGCGTCGCTGGATGCAGGCTCAGGGGAGCCCCCGATGGACTACCACGAGGATGACAA GCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTGGAGGCGGGCCTGGAGCTGGAGCG GGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACAT TAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCTGTGCTCCAGAAAATCACAGATCC CATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAA AACCCGGAGCACGATTGTCTATGAGATCTTGAAGAGAACGACGTGTACAAAGGCCAAGTA CAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCA CGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGA GTGGGCACGCTATGGAGTTTTCTATAAGTACCAGCCCATCGACCTGGTCAGGAAGTATTT TGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCC TGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACAT CCCCAGCATGGAGATGTGTGACCAGAGACACAATATCACCATGTGCCCGCTTTGCGACAA GACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTT CGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCAT GGAGCACTGGAAGCGGAAACAGATGCGACTCAACTACCGCTGGGACCTCACGGGCTTTGA AGAGGAAGAGGATCATCCTAGAGCTGAATACGAAGCAAGAGTCTTGGAGAAGTCTCTGAA GAAAGAGTCTAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCC AGCCTACCTCACTAACTTGGTCTCCATCATCTTCATGATTGCAGTGACGTTTGCCATCGT CCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCC CTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGT GGTCATCATCCTCCTGGACGAGGTGTATGGCTGCATAGCCCGATGGCTCACCAAGATCGA GGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAA GTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGG ACGCCCGGGCGACTACGTGTACATTTTCCGTTCCTTCCGAATGGAAGAGTGTGCGCCAGG GGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGAT CCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAA GCTGAAGCAGCAGAGCCCCCCTGACCACGAGGAGTGTGTGAAGAGGAAACAGCGGTACGA GGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCAT CCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCT GCTGAACAACATCATCGAGATCCGCCTGGACGCCAAAAAGTTTGTCACTGAGCTCCGAAG GCCGGTAGCTGTCAGAGCCAAAGACATCGGAATCTGGTACAATATCCTCAGAGGCATTGG GAAGCTTGCTGTCATCATCGATGCCTTCGTGATCTCCTTCACGTCTGACTTCATCCCGCG CCTGGTGTACCTCTACATGTACAGTAAGAACGGGACCATGCACGGCTTCGTCAACCACAC CCTCTCCTCCTTCAACGTCAGTGACTTCCAGAACGGCACGGCCCCCAATGACCCCCTGGA CCTGGGCTACGAGGTGCAGATCTGCAGGTATAAAGACTACCGAGAGCCGCCGTGGTCGGA AAACAAGTACGACATCTCCAAGGACTTCTGGGCCGTCCTGGCAGCCCGGCTGGCGTTTGT CATCGTCTTCCAGAACCTGGTCATGTTCATGAGCGACTTTGTGGACTGGGTCATCCCGGA CATCCCCAAGGACATCAGCCAGCAGATCCACAAGGAGAAGGTGCTCATGGTGGAGCTGTT CATGCGGGAGGAGCAAGACAAGCAGCAGCTGCTGGAAACCTGTATGGAGAAGGAGCGGCA GAAGGACGAGCCGCCGTGCAACCACCACAACACCAAAGCCTGCCCAGACAGCCTCGGCAG CCCAGCCCCCAGCCATGCCTACCACGGGGGCGTCCTGTAGCTATGCCAGCGGGGCTGGGC AGGCCAGCCGGGCATCCTGACCGATGGGCACCCTCTCCCAGGGCAGGCGGCTTCCCGCTC CCACCAGGGCCCGGAATGTCACTGTTGGACAATTATTTTAAAAGTGTATAAAACCAAGTC TCATAAATGATATGAGTGATCTAAATTTGCAGCAATGATACTAAACAACTCTCTGAAATT TCTCAAGCACCAAGAGAAACATCATTTTAGCAAAGGCCAGGAGGAAAAATAGAAATAAAT TTGTCTTGAAGATCCCAAAAAAAAAAAAAAAA >OriGene 5' read for BC033036 unedited
NAGAGTCTGTATTTGTATACGACTTCTATAGGCGGCCGCATAACTTCGTATAGCATACAT TATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGCGG GGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCGGCACCAA ATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCCTAGGG CCAGAGAGGCCAAGGTGCCAGGGACATGGCCCCAACTGTCCCCTAACCAGGGGTAGAGGA GTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTGGACCCTG ATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCC TGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACA GCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAAGGGGG CGTCGCTGGATGCAGGCTCATGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCT TCCGCANGGAGGAGTACGAGGGCAACCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACG AGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGTGCTGT GCANAGAGGCCCAGTTTCCTGAAAACTCGGAAAAAAGGCCCCCCCCCCCCNNGGNNNNNT NGGGGNGGGAGAGGGGAGAGGGGGTTATGGGACTTCCCGAATTGTGACTTTCCCTCTTTC TGCCCCACGCNCCTTAAAACGTAGTGTGTTGCCGGGGTGGGGCCCGCGCCACGATA |
| Restriction Sites | Please inquire |
| ACCN | BC033036 |
| Insert Size | 3277 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC033036.2, AAH33036.2 |
| RefSeq Size | 3272 bp |
| RefSeq ORF | 2520 bp |
| Locus ID | 55107 |
| Protein Families | Transmembrane |
| Gene Summary | Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Calcium-Activated Chloride Channel TMEM16A is Inhibitied by Liquiritigenin
,null,
Frontiers in Pharmacology
,PubMed ID 33897420
[ANO1]
|
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