OTUD5 (BC028225) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	deubiquinating enzyme A; DKFZp761A052; DUBA; MGC104871; OTTHUMP00000025821; OTU domain containing 5
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC028225 edited CGGCAGTGCAGCCATGACTATACTCCCCAAAAAGAAGCCGCCGCCTCCCGACGCCGACCC CGCCAACGAGCCGCCGCCGCCCGGGCCGATGCCCCCGGCGCCGCGGCGCGGCGGAGGTGT GGGCGTGGGCGGCGGCGGCACGGGCGTGGGCGGCGGCGATCGCGACCGTGACTCCGGCGT CGTGGGGGCCCGTCCGCGAGCTTCGCCACCGCCTCAAGGCCCGCTACCAGGACCGCCGGG CGCTCTTCATCGCTGGGCGCTGGCCGTGCCGCCTGGTGCAGTGGCGGGTCCCCGGCCACA ACAGGCTTCTCCACCTCCTTGCGGGGGCCCAGGTGGTCCCGGCGGCGGTCCCGGCGACGC GCTGGGCGCAGCGGCGGCGGGTGTGGGTGCCGCGGGCGTGGTGGTGGGTGTGGGTGGTGC CGTAGGCGTGGGCGGCTGCTGCTCCGGGCCTGGGCACAGCAAGCGGCGACGTCAAGCTCC CGGGGTTGGCGCGGTTGGCGGGGGCAGTCCCGAGCGTGAGGAGGTCGGCGCAGGCTACAA CAGTGAGGACGAGTATGAGGCGGCTGCAGCACGCATCGAGGCTATGGACCCTGCCACTGT CGAGCAGCAGGAGCATTGGTTTGAAAAGGCCCTACGAGACAAGAAGGGCTTCATCATCAA GCAGATGAAGGAGGATGGCGCCTGTCTCTTCCGGGCTGTAGCTGACCAGGTGTATGGAGA CCAGGACATGCATGAGGTTGTGCGAAAGCATTGCATGGACTATCTGATGAAGAATGCCGA CTACTTCTCCAACTATGTCACAGAGGACTTTACCACCTACATTAACAGGAAGCGGAAAAA CAATTGCCATGGCAACCACATTGAGATGCAGGCCATGGCAGAGATGTACAACCGTCCTGT GGAGGTGTACCAGTACAGCACAGAACCCATCAACACATTCCATGGGATACATCAAAACGA GGACGAACCCATTCGTGTTAGCTACCATCGGAATATCCACTATAATTCAGTGGTGAATCC TAACAAGGCCACCATTGGTGTGGGGCTGGGCCTGCCATCATTCAAACCAGGGTTTGCAGA GCAGTCTCTGATGAAGAATGCCATAAAAACATCGGAGGAGTCATGGATTGAACAGCAGAT GCTAGAAGACAAGAAACGGGCCACAGACTGGGAGGCCACAAATGAAGCCATCGAGGAGCA GGTGGCTCGGGAATCCTACCTGCAGTGGTTGCGGGATCAGGAGAAACAGGCTCGCCAGGT CCGAGGCCCCAGCCAGCCCCGGAAAGCCAGCGCCACATGCAGTTCGGCCACAGCAGCAGC CTCCAGTGGCCTGGAGGAGTGGACTAGCCGGTCCCCGCGGCAGCGGAGTTCAGCCTCGTC ACCTGAGCACCCTGAGCTGCATGCTGAATTGGGCATGAAGCCCCCTTCCCCAGGCACTGT TTTAGCTCTTGCCAAACCTCCTTCGCCCTGTGCGCCAGGTACAAGCAGTCAGTTCTCGGC AGGGGCCGACCGGGCAACTTCCCCCCTTGTGTCCCTCTACCCTGCTTTGGAGTGCCGGGC CCTCATTCAGCAGATGTCCCCCTCTGCCTTTGGTCTGAATGACTGGGATGATGATGAGAT CCTAGCTTCGGTGCTGGCAGTGTCCCAACAGGAATACCTAGACAGTATGAAGAAAAACAA AGTGCCCTGCAGGTGTTGACAAGATCCGCCATCTGTAATGTCCTTGGCACAATAAAACCA AATGTCAGTTTAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC028225 unedited NNNGGTGCGGTTCGAATTTGTATACGACTCATATAGGCGGCCGCGNATTCCCGGGATCGG CAGTGCAGCCATGACTATACTCCCCAAAAAAAAGCCGCCGCCTCCCGACGCCGACCCCGC CAACGAGCCGCCGCCGCCCGGGCCGATGCCCCCGGCGCCGCGGCGCGGCGGAGGTGTGGG CGTGGGCGGCGGCGGCACGGGCGTGGGCGGCGGCGATCGCGACCGTGACTCCGGCGTCGT GGGGGCCCGTCCGCGAGCTTCGCCACCGCCTCAAGGCCCGCTACCAGGACCGCCGGGCGC TCTTCATCGCTGGGCGCTGGCCGTGCCGCCTGGTGCAGTGGCGGGTCCCCGGCCACAACA GGCTTCTCCACCTCCTTGCGGGGGCCCAGGTGGTCCCGGCGGCGGTCCCGGCGACGCGCT GGGCGCAGCGGCGGCGGGTGTGGGTGCCGCGGGCGTGGTGGTGGGTGTGGGTGGTGCCGT ANGCGTGGGCGGCTGCTGCTCCGGGCCTGGGCACAGCAAGCGGCGACGTCAAGCTCCCGG GGTTGGCGCGGTTGGCGGGGGCAGTCCCGAGCGTGAGGAGGTCGGCGCAGGCTACAACAG TGAGGACGAGTATGAGGCGGCTGCAGCACGCATCGAGGCTATGGACCCTGCCACTGTCGA GCAGCAGGAGCATTGGTTTGAAAAGGCCCTACGAGACAAGAAGGGCTTCATCATCAAGCA GATGAAGGAGGATGGCGCCTGTCTCTTCCGGGCTGTAGCTGACCAGGTGTATGGAGACCA GGACATGCATGAGGTTGTGCGAAAGCATTGCATGGACTATCTGATGAAGAATGCCGACTA CTTCTNCCACTATGTCACAGAGGACTTTACCAC
Restriction Sites	Please inquire
ACCN	BC028225
Insert Size	1777 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC028225.1, AAH28225.1
RefSeq Size	1777 bp
Locus ID	55593
Protein Families	Protease
Protein Pathways	RIG-I-like receptor signaling pathway
Gene Summary	This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.