TBK1 (BC009864) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC009864 edited GGCACGAGGGACCAGTCTTTGGTTATACATTTGGCAATTACTTGGGAGTTGTTTTGAGGC CACCTACTAAGAATACTTGGGATAGAGATTACAAATTAAACCCATAAGCCAGGTAGACGA GGAGCAAGGAAATGTCTGGGAATTCGTATTTCATCGGCATATATTTAAAACATCTTATGC TTCTAATTTCCGGTGTGAGTCAACCTCTGCGGACTGAACATCACTAAAACTCTAAGGAAA CGTCTCTTTTTAATCCTCTGAAAAATCAATACATTTAAAAACTGCCCGTTGTGTCGACGC TCGGAAAGAGGGTAGAAAACAGCGAGTCTAAGGGAAAGAGGTGCCCCTGCCTCCCCAGGC AGCCAGGGCCCAGGCCCGGTAACGGAGTCGTCCTCTTTATGCCCAAAGCCGCCGGACGGG ATGCAGGTCGAGGACCGGCCGCGCGGCGCGGAGCGGGGATGCAGGTAACAGGGCCCGCGC GACCATTCCACCGGCTACGGCCACCCGACACACACCCCAGAGGCAGTGTCCACGCAGCCG GGGTCCTGGATGGCTTGGCCTCGGGTCGTCCGGGGCTTCTCGGTGCGCCCGCCCCCGCCC CCGCTCTGACTCAGCATCCCAGCCTCCCACAGGGGGCGGGAGCGCTCCCCGCCGGGCGGC GCAGGCCTGACCGACCGCGCCCCGCGCCGCCTTGGCCCCTCAGCCCGCGGCCGTCTCACT TACCCAGCCGGGTCTCCGCCGCGCCACCGCCGGCGGGCTCCCGCGGCCTCCTCGAGACTC AGGACACTTCCGGCTTCGCAAGCCCTGGCCGGAGGCCACGTGACCGACGGCCGGCGCGCC GGTGCGGGTGCGCGTGCGCACGCCTATGGCCCGTCTGGTAGTCACCACAGCCGCGGCGGC AACTGCCGAGTCGGCTTCCGCGGCCACGGTAATGAGGGGGATGTCTGGAGACACCCCGTC CACTGTTGCCCTCGCCCTTTACTCTAAAGGGGAATGAGGAGCCCTGAGCAGCGAACACAG TAATTGGGATTCCCGCAACTGCAAATCCCGCCCCTTCCCCGAGCGCTGGCCGACAGTAGG GCGGACCGACGCTGAGCAAGGGATTACATCCCAAGATTTACAGGTGTGCAGAACGTGGGA CACGTGGGGGGCAGGCACAGACGGCCGGCAGAGCTGGGAGGGATGGATTCTATGTTTTAA GGGCCCACTTTGGCTGCAGTGGAGCCAGATTATCGTCTCGCAGTAATTCAGACTTTACAT TGTTTTTTTCATTTTCCCATCACCCAGAAATACATTAAATTCTTAATGTAAAAATGTTCA AAAAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC009864 unedited NGGGAGTTCANAATTTTGTAATACGACTTCATTATAGGGCCGNGCCGCGCAATTCGTATT TCATCGGCATATATTTAAAACATCTTATGCTTCTAATTTCCGGTGTGAGTCAACCTCTGC GGACTGAACATCACTAAAACTCTAAGGAAACGTCTCTTTTTANATCCTCTGAAAAATCAA TACATTTAAAAACTGCCCGTTGTGTCGACGCTCGGAAAGAGGGTAGAAAACAGCGAGTCT AAGGGAAAGAGGTGCCCCTGCCTCCCCAGGCAGCCAGGGCCCAGGCCCGGTAACGGAGTC GTCCTCTTTATGCCCAAAGCCGCCGGACGGGATGCAGGTCGAGGACCGGCCGCGCGGCGC GGAGCGGGGATGCAGGTAACAGGGCCCGCGCGACCATTCCACCGGCTACGGCCACCCGAC ACACACCCCAGAGGCAGTGTCCACGCAGCCGGGGTCCTGGATGGCTTGGCCTCGGGTCGT CCGGGGCTTCTCGGTGCGCCCGCCCCCGCCCCCGCTCTGACTCAGCATCCCAGCCTCCCA CAGGGGGCGGGAGCGCTCCCCGCCGGGCGGCGCAGGCCTGACCGACCGCGCCCCGCGCCG CCTTGGCCCCTCAGCCCGCGGCCGTCTCACTTACCCAGCCGGGTCTCCGCCGCGCCACCG CCGGCGGGCTCCCGCGGCCTCCTCGAGACTCAGGACACTTCCGGCTTCGCAAGCCCTGGC CGGAGGCCACGTGACCGACNGCCGGCGCGCCGGTGCGGGTGCGCGTGCGCACGCCTATGG CCCGTCTGGTAGTCACCACAGCCGCGGCGGCAACTGCCGAGTCGGCTTCCGCGGCCACGG TAATGAAGGGGGATGTCTGGAGACACCCCGTTCACTGTTGCCCTCGCCCTTTACTCTAAA GGGGAATGAGGAGCCCTGC
Restriction Sites	Please inquire
ACCN	BC009864
Insert Size	1349 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC009864.1, AAH09864.1
RefSeq Size	1349 bp
Locus ID	29110
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Gene Summary	The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

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