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MMP3 (NM_002422) Human Untagged Clone
CAT＃: SC123913
MMP3 (untagged)-Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3)
CNY 3,656.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC123913 sequence for NM_002422 edited (data generated by NextGen Sequencing)
ATGAAGAGTCTTCCAATCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATCCATTG GATGGAGCTGCAAGGGGTGAGGACACCAGCATGAACCTTGTTCAGAAATATCTAGAAAAC TACTACGACCTCGAAAAAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTT GTTAAAAAAATCCGAGAAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGAC TCCGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGAGTTCCTGACGTTGGTCACTTC AGAACCTTTCCTGGCATCCCGAAGTGGAGGAAAACCCACCTTACATACAGGATTGTGAAT TATACACCAGATTTGCCAAAAGATGCTGTTGATTCTGCTGTTGAGAAAGCTCTGAAAGTC TGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATG ATCTCTTTTGCAGTTAGAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTT TTGGCCCATGCCTATGCCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGAT GAACAATGGACAAAGGATACAACAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATT GGCCACTCCCTGGGTCTCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTAT CACTCACTCACAGACCTGACTCGGTTCCGCCTGTCTCAAGATGATATAAATGGCATTCAG TCCCTCTATGGACCTCCCCCTGACTCCCCTGAGACCCCCCTGGTACCCACGGAACCTGTC CCTCCAGAACCTGGGACGCCAGCCAACTGTGATCCTGCTTTGTCCTTTGATGCTGTCAGC ACTCTGAGGGGAGAAATCCTGATCTTTAAAGACAGGCACTTTTGGCGCAAATCCCTCAGG AAGCTTGAACCTGAATTGCATTTGATCTCTTCATTTTGGCCATCTCTTCCTTCAGGCGTG GATGCCGCATATGAAGTTACTAGCAAGGACCTCGTTTTCATTTTTAAAGGAAATCAATTC TGGGCCATCAGAGGAAATGAGGTACGAGCTGGATACCCAAGAGGCATCCACACCCTAGGT TTCCCTCCAACCGTGAGGAAAATCGATGCAGCCATTTCTGATAAGGAAAAGAACAAAACA TATTTCTTTGTAGAGGACAAATACTGGAGATTTGATGAGAAGAGAAATTCCATGGAGCCA GGCTTTCCCAAGCAAATAGCTGAAGACTTTCCAGGGATTGACTCAAAGATTGATGCTGTT TTTGAAGAATTTGGGTTCTTTTATTTCTTTACTGGATCTTCACAGTTGGAGTTTGACCCA AATGCAAAGAAAGTGACACACACTTTGAAGAGTAACAGCTGGCTTAATTGTTGA Clone variation with respect to NM_002422.3 133 a=>g;288 t=>c;1086 t=>c >OriGene 5' read for NM_002422 unedited
NGGTCAGTCAAATATTTGTAATAGACTCACTATAGGCGGCCGCGNAATTCGCACCAGNAC AGCAAGGCATAGAGACAACATAGAGCTAAGTAAAGCCAGTGGAAATGAAGAGTCTTCCAA TCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATCCATTGGATGGAGCTGCAAGGG GTGAGGACACCAGCATGAACCTTGTTCAGAAATATCTAGAAAACTACTACGACCTCGAAA AAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTTGTTAAAAAAATCCGAG AAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGACTCCGACACTCTGGAGG TGATGCGCAAGCCCAGGTGTGGAGTTCCTGACGTTGGTCACTTCAGAACCTTTCCTGGCA TCCCGAAGTGGAGGAAAACCCACCTTACATACAGGATTGTGAATTATACACCAGATTTGC CAAAAGATGCTGTTGATTCTGCTGTTGAGAAAGCTCTGAAAGTCTGGGAAGAGGTGACTC CACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATGATCTCTTTTGCAGTTA GAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTTTTGGCCCATGCCTATG CCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGATGAACAATGGACAAAGG ATACAACAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATTGGCCACTCCCTGGGTC TCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTATCACTCACTCACAGACC TGACTCGGGTCCGCCTGTCTCAAGAGATATAAAGGC >OriGene 3' read for NM_002422 unedited
TTTCCGGCCAGGAGTTGCACAGAGGAGCCGTCACAGGGATGCCACCCGGGATCTGTTCAG GAAACAGCTATGACCTGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAA TAACTGACAAATCGTCTTTATTAAATAAGCAAATAGTCTACACAGATACAGTCACTTGTC TGTTGCACACGAGTGCTTCCCCTTCTCTTGGGAAAGATCACTCTATGTGACAAGGTGCAA GCTAAGCAGCAGCCCATTTGAATGCCCTGTAATAACATAAAAATGACCGGCAAGATACAG ATTCACGCTCAAGTTCCCTTGAGTGTGACTCGAGTCACAGCACAGGCAGGAGAAAACGAA CATTTCAATTCACAGAGACTTAGGTGAAGAATTATTAGCTTCATTTAAAGTGCCCATATT GTGCCTTCTACATATCTCTTTCAACAATTAAGCCAGCTGTTACTCTTCAAAGTGTGTGTC ACTTTCTTTGCATTTGGGTCAAACTCCAACTGTGAAGATCCAGTAAAGAAATAAAAGAAC CCAAATTCTTCAAAAACAGCATCAATCTTTGAGTCAATCCCTGGAAAGTCTTCAGCTATT TGCTTGGGAAAGCCTGGCTCCATGGAATTTCTCTTCTCATCAAATCTCCAGTATTTGTCC TCTACAAAGAAATATGTTTTGTTCTTTTCCTTATCAGAAATGGCTGCATCGATTTTCCT |
| Restriction Sites | Please inquire |
| ACCN | NM_002422 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002422.3, NP_002413.1 |
| RefSeq Size | 1828 bp |
| RefSeq ORF | 1434 bp |
| Locus ID | 4314 |
| UniProt ID | P08254 |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The inhibitor of kappa B kinase-epsilon regulates MMP-3 expression levels and can promote lung metastasis
,Seccareccia, E;Pinard, M;Wang, N;Li, S;Burnier, J;Dankort, D;Brodt, P;,
Oncogenesis
,PubMed ID 25133483
[MMP3]
|
|
Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3
,Robichaud, N;Del Rincon, SV;Huor, B;Alain, T;Petruccelli, LA;Hearnden, J;Goncalves, C;Grotegut, S;Spruck, CH;Furic, L;Larsson, O;Muller, WJ;Miller, WH;Sonenberg, N;,
Oncogene
,PubMed ID 24909168
[MMP3]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210235 | MMP3 (Myc-DDK-tagged)-Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3) |
CNY 3,656.00 |
|
| RC210235L1 | Lenti ORF clone of Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210235L2 | Lenti ORF clone of Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), mGFP tagged |
CNY 5,890.00 |
|
| RC210235L3 | Lenti ORF clone of Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210235L4 | Lenti ORF clone of Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), mGFP tagged |
CNY 6,056.00 |
|
| RG210235 | MMP3 (tGFP-tagged) - Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3) |
CNY 5,256.00 |
