United States
Germany
Japan
United Kingdom
China
MMP12 (NM_002426) Human Untagged Clone
CAT＃: SC123937
MMP12 (untagged)-Human matrix metallopeptidase 12 (macrophage elastase) (MMP12)
CNY 3,656.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HME; ME; MME; MMP-12 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002426 edited
AATTGATCCGTTTAGAAGTTTACAATGAAGTTTCTTCTAATACTGCTCCTGCAGGCCACT GCTTCTGGAGCTCTTCCCCTGAACAGCTCTACAAGCCTGGAAAAAAATAATGTGCTATTT GGTGAAAGATACTTAGAAAAATTTTATGGCCTTGAGATAAACAAACTTCCAGTGACAAAA ATGAAATATAGTGGAAACTTAATGAAGGAAAAAATCCAAGAAATGCAGCACTTCTTGGGT CTGAAAGTGACCGGGCAACTGGACACATCTACCCTGGAGATGATGCACGCACCTCGATGT GGAGTCCCCGATGTCCATCATTTCAGGGAAATGCCAGGGGGGCCCGTATGGAGGAAACAT TATATCACCTACAGAATCAATAATTACACACCTGACATGAACCGTGAGGATGTTGACTAC GCAATCCGGAAAGCTTTCCAAGTATGGAGTAATGTTACCCCCTTGAAATTCAGCAAGATT AACACAGGCATGGCTGACATTTTGGTGGTTTTTGCCCGTGGAGCTCATGGAGACTTCCAT GCTTTTGATGGCAAAGGTGGAATCCTAGCCCATGCTTTTGGACCTGGATCTGGCATTGGA GGGGATGCACATTTCGATGAGGACGAATTCTGGACTACACATTCAGGAGGCACAAACTTG TTCCTCACTGCTGTTCACGAGATTGGCCATTCCTTAGGTCTTGGCCATTCTAGTGATCCA AAGGCCGTAATGTTCCCCACCTACAAATATGTTGACATCAACACATTTCGCCTCTCTGCT GATGACATACGTGGCATTCAGTCCCTGTATGGAGACCCAAAAGAGAACCAACGCTTGCCA AATCCTGACAATTCAGAACCAGCTCTCTGTGACCCCAATTTGAGTTTTGATGCTGTCACT ACCGTGGGAAATAAGATCTTTTTCTTCAAAGACAGGTTCTTCTGGCTGAAGGTTTCTGAG AGACCAAAGACCAGTGTTAATTTAATTTCTTCCTTATGGCCAACCTTGCCATCTGGCATT GAAGCTGCTTATGAAATTGAAGCCAGAAATCAAGTTTTTCTTTTTAAAGATGACAAATAC TGGTTAATTAGCAATTTAAGACCAGAGCCAAATTATCCCAAGAGCATACATTCTTTTGGT TTTCCTAACTTTGTGAAAAAAATTGATGCAGCTGTTTTTAACCCACGTTTTTATAGGACC TACTTCTTTGTAGATAACCAGTATTGGAGGTATGATGAAAGGAGACAGATGATGGACCCT GGTTATCCCAAACTGATTACCAAGAACTTCCAAGGAATCGGGCCTAAAATTGATGCAGTC TTCTACTCTAAAAACAAATACTACTATTTCTTCCAAGGATCTAACCAATTTGAATATGAC TTCCTACTCCAACGTATCACCAAAACACTGAAAAGCAATAGCTGGTTTGGTTGTTAGAAA TGGTGTAATTAATGGTTTTTGTTAGTTCACTTCAGCTTAATAAGTATTTATTGCATATTT GCTATGTCCTCAGTGTACCACTACTTAGAGATATGTATCATAAAAATAAAATCTGTAAAC CATAGGTAATGATTATATAAAATACATAATATTTTTCAATTTTGAAAACTCTAATTGTCC ATTCTTGCTTGACTCTACTATTAAGTTTGAAAATAGTTACCTTCAAAGGCCAAGAGAATT CTATTTGAAGCATGCTCTGTAAGTTGCTTCCTAACATCCTTGGACTGAGAAATTATACTT ACTTCTGGCATAACTAAAATTAAGTATATATATTTTGGCTCAAATAAATTTGAAAAAAAA AAAAAAAAAAA >OriGene 5' read for NM_002426 unedited
TAAAGTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGAATTGAT CCGTTTAGAAGTTTACAATGAAGTTTCTTCTAATACTGCTCCTGCAGGCCACTGCTTCTG GAGCTCTTCCCCTGAACAGCTCTACAAGCCTGGAAAAAAATAATGTGCTATTTGGTGAAA GATACTTAGAAAAATTTTATGGCCTTGAGATAAACAAACTTCCAGTGACAAAAATGAAAT ATAGTGGAAACTTAATGAAGGAAAAAATCCAAGAAATGCAGCACTTCTTGGGTCTGAAAG TGACCGGGCAACTGGACACATCTACCCTGGAGATGATGCACGCACCTCGATGTGGAGTCC CCGATGTCCATCATTTCAGGGAAATGCCAGGGGGGCCCGTATGGAGGAAACATTATATCA CCTACAGAATCAATAATTACACACCTGACATGAACCGTGAGGATGTTGACTACGCAATCC GGAAAGCTTTCCAAGTATGGAGTAATGTTACCCCCTTGAAATTCAGCAAGATTAACACAG GCATGGCTGACATTTTGGTGGTTTTTGCCCGTGGAGCTCATGGAGACTTCCATGCTTTTG ATGGCAAAGGTGGAATCCTAGCCCATGCTTTTGGACCTGGATCTGGCATTGGAGGGGATG CACATTTCGATGAGGACGAATTCTGGACTACACATTCAGGAGGCACAAACTTGGTCCTCA CTGCTGTTCACGAGATTGGCCATTCCTTANGTCTTGGCCATTCTAGTGATCCAAAGGCCG TAATGTTTCCCCCCTACCAATATGTTGACATCACACCTTTCGGCTCTCTGCTGATGACAT ACCTGGCATTCAGTCCCTGTATGGGGACCCCANAAAAACCCACCGCTTGCCCAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002426 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_002426. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002426.2, NP_002417.2 |
| RefSeq Size | 1825 bp |
| RefSeq ORF | 1413 bp |
| Locus ID | 4321 |
| UniProt ID | P39900 |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Matrix metalloproteinase-12 (MMP-12) SNP affects MMP activity, lung macrophage infiltration and protects against emphysema in COPD
,Imran Haq, Gillian E Lowrey, Noor Kalsheker, and Simon R Johnson,
Thorax, Nov 2011; 66: 970 - 976.
[MMP12]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223246 | MMP12 (Myc-DDK-tagged)-Human matrix metallopeptidase 12 (macrophage elastase) (MMP12) |
CNY 3,656.00 |
|
| RC223246L1 | Lenti ORF clone of Human matrix metallopeptidase 12 (macrophage elastase) (MMP12), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC223246L2 | Lenti ORF clone of Human matrix metallopeptidase 12 (macrophage elastase) (MMP12), mGFP tagged |
CNY 6,056.00 |
|
| RC223246L3 | Lenti ORF clone of Human matrix metallopeptidase 12 (macrophage elastase) (MMP12), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC223246L4 | Lenti ORF clone of Human matrix metallopeptidase 12 (macrophage elastase) (MMP12), mGFP tagged |
CNY 6,056.00 |
|
| RG223246 | MMP12 (tGFP-tagged) - Human matrix metallopeptidase 12 (macrophage elastase) (MMP12) |
CNY 5,256.00 |
