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KCNA5 (NM_002234) Human Untagged Clone
CAT＃: SC123964
KCNA5 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5)
CNY 6,856.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002234, the custom clone sequence may differ by one or more nucleotides
ATGGAGATCGCCCTGGTGCCCCTGGAGAACGGCGGTGCCATGACCGTCAGAGGAGGCGATGAGGCCCGGG CAGGCTGCGGCCAGGCCACAGGGGGAGAGCTCCAGTGTCCCCCGACGGCTGGGCTCAGCGATGGGCCCAA GGAGCCGGCGCCAAAGGGGCGCGGCGCGCAGAGAGACGCGGACTCGGGAGTGCGGCCCTTGCCTCCGCTG CCGGACCCGGGAGTGCGGCCCTTGCCTCCGCTGCCAGAGGAGCTGCCACGGCCTCGACGGCCGCCTCCCG AGGACGAGGAGGAAGAAGGCGATCCCGGCCTGGGCACGGTGGAGGACCAGGCTCTGGGCACGGCGTCCCT GCACCACCAGCGCGTCCACATCAACATCTCCGGGCTGCGCTTTGAGACGCAGCTGGGCACCCTGGCGCAG TTCCCCAACACACTCCTGGGGGACCCCGCCAAGCGCCTGCGCTACTTCGACCCCCTGAGGAACGAGTACT TCTTCGACCGCAACCGGCCCAGCTTCGACGGTATCCTCTACTACTACCAGTCCGGGGGCCGCCTGCGGAG GCCGGTCAACGTCTCCCTGGACGTGTTCGCGGACGAGATACGCTTCTACCAGCTGGGGGACGAGGCCATG GAGCGCTTCCGCGAGGATGAGGGCTTCATTAAAGAAGAGGAGAAGCCCCTGCCCCGCAACGAGTTCCAGC GCCAGGTGTGGCTTATCTTCGAGTATCCGGAGAGCTCTGGGTCCGCGCGGGCCATCGCCATCGTCTCGGT CTTGGTTATCCTCATCTCCATCATCACCTTCTGCTTGGAGACCCTGCCTGAGTTCAGGGATGAACGTGAG CTGCTCCGCCACCCTCCGGCGCCCCACCAGCCTCCCGCGCCCGCCCCTGGGGCCAACGGCAGCGGGGTCA TGGCCCCGCCCTCTGGCCCTACGGTGGCACCGCTCCTGCCCAGGACCCTGGCCGACCCCTTCTTCATCGT GGAGACCACGTGCGTCATCTGGTTCACCTTCGAGCTGCTCGTGCGCTTCTTCGCCTGCCCCAGCAAGGCA GGGTTCTCCCGGAACATCATGAACATCATCGATGTGGTGGCCATCTTCCCCTACTTCATCACCCTGGGCA CCGAACTGGCAGAGCAGCAGCCAGGGGGTGGAGGAGGCGGCCAGAATGGGCAGCAGGCCATGTCCCTGGC CATCCTCCGAGTCATCCGCCTGGTCCGGGTGTTCCGCATCTTCAAGCTCTCCCGCCACTCCAAGGGGCTG CAGATCCTGGGCAAGACCTTGCAGGCCTCCATGAGGGAGCTGGGGCTGCTCATCTTCTTCCTCTTCATCG GGGTCATCCTCTTCTCCAGTGCCGTCTACTTCGCAGAGGCTGACAACCAGGGAACCCATTTCTCTAGCAT CCCTGACGCCTTCTGGTGGGCAGTGGTCACCATGACCACTGTGGGCTACGGGGACATGAGGCCCATCACT GTTGGGGGCAAGATCGTGGGCTCGCTGTGTGCCATCGCCGGGGTCCTCACCATTGCCCTGCCTGTGCCCG TCATCGTCTCCAACTTCAACTACTTCTACCACCGGGAAACGGATCACGAGGAGCCGGCAGTCCTTAAGGA AGAGCAGGGCACTCAGAGCCAGGGGCCGGGGCTGGACAGAGGAGTCCAGCGGAAGGTCAGCGGGAGCAGG GGATCCTTCTGCAAGGCTGGGGGGACCCTGGAGAATGCAGACAGTGCCCGAAGGGGCAGCTGCCCCCTAG AGAAGTGTAACGTCAAGGCCAAGAGCAACGTGGACTTGCGGAGGTCCCTTTATGCCCTCTGCCTGGACAC CAGCCGGGAAACAGATTTGTGA >OriGene 5' read for NM_002234 unedited
NTTTCCCTGGAGAACGCGGTGCCATGACCGTCAGAGGAGGCGATGAGGCCCGGGCAGGCT GCGGCCAGGCCACAGGGGGAGAGCTCCAGTGTCCCCCGACGGCTGGGCTCAGCGATGGGC CCAAGGAGCCGGCGCCAAAGGGGCGCGGCGCGCAGAGAGACGCGGACTCGGGAGTGCGGC CCTTGCCTCCGCTGCCGGACCCGGGAGTGCGGCCCTTGCCTCCGCTGCCAGAGGAGCTGC CACGGCCTCGACGGCCGCCTCCCGAGGACGAGGAGGAAGAAGGCGATCCCGGCCTGGGCA CGGTGGAGGACCAGGCTCTGGGCACGGCGTCCCTGCACCACCAGCGCGTCCACATCAACA TCTCCGGGCTGCGCTTTGAGACGCAGCTGGGCACCCTGGCGCAGTTCCCCAACACACTCC TGGGGGACCCCGCCAAGCGCCTGCGCTACTTCGACCCCCTGAGGAACGAGTACTTCTTCG ACCGCAACCGGCCCAGCTTCGACGGTATCCTCTACTACTACCAGTCCGGGGGCCGCCTGC GGAGGCCGGTCAACGTCTCCCTGGACGTGTTCGCGGACGAGATACGCTTCTACCAGCTGG GGGACGAGGCCATGGAGCGCTTCCGCGAGGATGAGGGCTTCATTAAAGAAGAGGAGAAGC CCCTGCCCCGCAACGAGTTCCAGCGCCAGGTGTGGCTTATCNTCGAGTATCCGGAGAGCT CTGGGTCCGCGCGGGCCATCGCCATCGTCTCGGTCTTGGTTATCTCATCTCCTCATCACC TTCTGCTTGAGACCNTGCTGAGTTAGGGATGACGTGAGCTGCTCCN >OriGene 3' read for NM_002234 unedited
NTTGCCTGGATGGCACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCA CCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTCTT TCTTTGGGTTTTTTTGCAACAAGGTAACGGTTTATTTCCTGGGATAAAAATAAAGACAAT AAATTATCAGAAGTATTCCTCCAATATCATTAAAATGCTTTTTGAAGAAAGTTACAAGAA TTGTTTAAGGCGCACAGAAAAAGTCAGATTTGCCTTTCTTCAAGAACATACTCTGCCCTA GACACAAAGCACCAATACCACATCCCAGAAAAGACAGAGGCTTGGAGACACATGAAACAG ATCAGCCCATACCAAGATCTCTGACTCTAATATAAGTAACACAGAAAAACATCGGGACAA CACTTTCTTCCATAAATACAACATGTATCTTGAAAATATACCCAAAATATCTCTATCTGA ACTACAGTACAAAAAGCCACTTACCAGGCATAAAAATAATATTTTCCCCTATACACGAAT ACAATCATATGTCAAGCAAATTTGGAACACATTGATGGGAGAGTTACATAATCTCTTTGG ATCTGGGCTATTTAGAGTCATTTTTGTTTGGGGTATGCCTCTGCTTGGGTATACGAGACT GGCTACAAATACATNCATTCCTAAAGCGGTTAACAATTTCAACAACCTCTCGGTTATTGG AATGGGGTACTTTTTAAAAATAAGGCACACCTTGGTGTGTTGGAAAGGAATTATCAAATT GGGGGGGTCTCGGGGGGGGGGGAAAAAGGTTTAAAGGGAGGGGGTATCTGNG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002234 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002234.2, NP_002225.2 |
| RefSeq Size | 2865 bp |
| RefSeq ORF | 1842 bp |
| Locus ID | 3741 |
| UniProt ID | P22460 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219793 | KCNA5 (Myc-DDK-tagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5) |
CNY 6,848.00 |
|
| RC219793L1 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5), Myc-DDK-tagged |
CNY 9,248.00 |
|
| RC219793L2 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5), mGFP tagged |
CNY 5,890.00 |
|
| RC219793L3 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219793L4 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5), mGFP tagged |
CNY 9,248.00 |
|
| RG219793 | KCNA5 (tGFP-tagged) - Human potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5) |
CNY 8,448.00 |
