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GATA4 (NM_002052) Human Untagged Clone
CAT＃: SC124037
GATA4 (untagged)-Human GATA binding protein 4 (GATA4)
CNY 3,656.00
CNY 7,220.00
| Cited in 5 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ASD2; TACHD; TOF; VSD1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124037 sequence for NM_002052 edited (data generated by NextGen Sequencing)
ATGTATCAGAGCTTGGCCATGGCCGCCAACCACGGGCCGCCCCCCGGTGCCTACGAGGCGGGCGGCCCCG GCGCCTTCATGCACGGCGCGGGCGCCGCGTCCTCGCCAGTCTACGTGCCCACACCGCGGGTGCCCTCCTC CGTGCTGGGCCTGTCCTACCTCCAGGGCGGAGGCGCGGGCTCTGCGTCCGGAGGCGCCTCGGGCGGCAGC TCCGGTGGGGCCGCGTCTGGTGCGGGGCCCGGGACCCAGCAGGGCAGCCCGGGATGGAGCCAGGCGGGAG CCGACGGAGCCGCTTACACCCCGCCGCCGGTGTCGCCGCGCTTCTCCTTCCCGGGGACCACCGGGTCCCT GGCGGCCGCCGCCGCCGCTGCCGCGGCCCGGGAAGCTGCGGCCTACAGCAGTGGCGGCGGAGCGGCGGGT GCGGGCCTGGCGGGCCGCGAGCAGTACGGGCGCGCCGGCTTCGCGGGCTCCTACTCCAGCCCCTACCCGG CTTACATGGCCGACGTGGGCGCGTCCTGGGCCGCAGCCGCCGCCGCCTCCGCCGGCCCCTTCGACAGCCC GGTCCTGCACAGCCTGCCCGGCCGGGCCAACCCGGCCGCCCGACACCCCAATCTCGATATGTTTGACGAC TTCTCAGAAGGCAGAGAGTGTGTCAACTGTGGGGCTATGTCCACCCCGCTCTGGAGGCGAGATGGGACGG GTCACTATCTGTGCAACGCCTGCGGCCTCTACCACAAGATGAACGGCATCAACCGGCCGCTCATCAAGCC TCAGCGCCGGCTGTCCGCCTCCCGCCGAGTGGGCCTCTCCTGTGCCAACTGCCAGACCACCACCACCACG CTGTGGCGCCGCAATGCGGAGGGCGAGCCTGTGTGCAATGCCTGCGGCCTCTACATGAAGCTCCACGGGG TCCCCAGGCCTCTTGCAATGCGGAAAGAGGGGATCCAAACCAGAAAACGGAAGCCCAAGAACCTGAATAA ATCTAAGACACCAGCAGCTCCTTCAGGCAGTGAGAGCCTTCCTCCCGCCAGCGGTGCTTCCAGCAACTCC AGCAACGCCACCACCAGCAGCAGCGAGGAGATGCGTCCCATCAAGACGGAGCCTGGTCTGTCATCTCACT ACGGGCACAGCAGCTCCGTGTCCCAGACGTTCTCAGTCAGTGCGATGTCTGGCCATGGGCCCTCCATCCA CCCTGTCCTCTCGGCCCTGAAGCTCTCCCCACAAGGCTATGCGTCTCCCGTCAGCCAGTCTCCACAGACC AGCTCCAAGCAGGACTCTTGGAACAGCCTGGTCTTGGCCGACAGTCACGGGGACATAATCACTGCGTAA Clone variation with respect to NM_002052.3 353 c=>n;354 g=>n;355 g=>n;356 c=>n;357 c=>n;358 g=>n;359 c=>n;360 c=>n;361 g=>n;1107 c=>t >OriGene 5' read for NM_002052 unedited
GGTCAGATTTGTATACGACTCATATAGGCGGCCGCGAATTCGCACGAGCGCAGGGCCGCG AGAGGCTTCGTCGCCGCTGCAGCTCCGGGGGCTCCCAGGGGAGCGTGCGCGGAACCTCCA GGCCCAGCAGGACCCCGGCTGCGGCGAGGAGGAAGGAGCCAGCCTAGCAGCTTCTGCGCC TGTGGCCGCGGGTGTCCTGGAGGCCTCTCGGTGTGACGAGTGGGGGACCCGAAGGCTCGT GCGCCACCTCCAGGCCTGGACGCTGCCCTCCGTCTTCTGCCCCCAATAGGTGCGCCGGAC CTTCAGGCCCTGGGGTGAATTCAGCTGCTCCTACATCAGCTTCCGGAACCACCAAAAATT CAAATTGGGATTTTCCGGAGTAAACAAGAGCCTAGAGCCCTTTGCTCAATGCTGGATTTA ATACGTATATATTTTTAAGCGAGTTGGTTTTTTCCCCTTTGATTTTTGATCTTCGCGACA GTTCCTCCCACGCATATTATCGTTGTTGCCGTCGTTTTCTCTCCCCGCGTGGCTCCTTGA CCTGCGAGGGAGAGAGAGGACACCGAAGCCGGGAGCTCGCAGGGACCATGTATCAGAGCT TGGCCATGGCCGCCAACCACGGGCCGCCCCCCGGTGCCTACGAGGCGGGCGGCCCCGGCG CCTTCATGCACGGCGCGGGCGCCGCGTCCTCGCCAGTCTACGTGCCCACACCGCGGGGTG CCCTCCTCCGTGCTGGGCCTGTCCTACCTCCAGGGCGGAGGCGCGGGCTCTGCGTCCGGG AGCGCCCTCGGCGGCAGCTCCGGGTGGGGCCCGGTCTGTTGCCGGGCCCGGNACCCCACA GGGCAGCCCGGGGAGGACCCAGCGCGGGGCCAACGAGCCGCTTACCCCCCGCCGCCGTGT CTCCCGCCCTTTTCCTCG >OriGene 3' read for NM_002052 unedited
GCATGGCAACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGG ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTGT TTTTTAAAGAGGAATACAGATAAATTTATTAGTTAAATACTGATTTTCCAGCCATTTCAC CTTAAGACAATGTTAACAGGTTTGTGGGTTAGGGAGGGTATACGAGGGGGCCTTTGGAAG AAAACAATGTAAATGATGATTAAAACAGAATCTTGGTTCAAAGGTATTCTCTGCTACAGC CAGTAGGATTTTGGAGTGAGGGGTCTGGGCGTGTGGGGAGGCGTAGTAATGCCACAGTCA GCTACAGCTCTGCTGAGAAAGAGGAAGGAGTCTCCATGAGCTCCAGCATCAGGGGCAGAA ACAGCAATGTGCAGAGGAGAACGCGGCAGATCCCGGAGCAGCTCAGAGTCGGAGGCTCCC TCCAGGCCCCCCTGCCGTGTCTTAGCAGTCGTCTTCTTTCCAGGAATTCTGTTGTGTTGT GTTTGTTTGCTTCGAATTCGTGTTGCAGAATCTCTGGCTTTTTGCCTCCTGGACAAAAGA CTTCTGCCGGGGCGAAGCTGCAAGTCCTTGAGGACTCTGGCTTGCATCTTGACCAAGGGT AGGAGGACCAACAGACCACAGGTGGGCCACCTTGGGACACTCTGCCCCTGACAGGAATTT GTCACTTACCTCTCCCAGAAGACCTCAGGCTGGCTGATGCTGCCAATGCTTGACACAAAC GTTTGTTTTCTAAACCTTTATTTGACCGTGACAAGGCTCATGACTCAGGGGTCGTTGTAA TCCAACCTTGTTCAGGAAAAATTCAACG |
| Restriction Sites | Please inquire |
| ACCN | NM_002052 |
| Insert Size | 3600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002052.2, NP_002043.2 |
| RefSeq Size | 3372 bp |
| RefSeq ORF | 1329 bp |
| Locus ID | 2626 |
| UniProt ID | P43694 |
| Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
| Gene Summary | This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Loss of GATA5 expression due to gene promoter methylation induces growth and colony formation of hepatocellular carcinoma cells
,Xia, L;Gong, Y;Zhang, A;Cai, S;,
Oncology Letters Nov2015
[GATA4]
|
|
Direct Reprogramming of Human Fibroblasts to Hepatocyte-Like Cells by Synthetic Modified mRNAs
,Simeonov, KP;Uppal, H;,
PLoS ONE
,PubMed ID 24963715
[GATA4]
|
|
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas
,null,
The Journal of Experimental Medicine
,PubMed ID 21464220
[GATA4]
|
|
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas
,Sameer Agnihotri, Amparo Wolf, Diana M. Munoz, Christopher J. Smith, Aaron Gajadhar, Andres Restrepo, Ian D. Clarke, Gregory N. Fuller, Santosh Kesari, Peter B. Dirks, C. Jane McGlade, William L. Stanford, Kenneth Aldape, Paul S. Mischel, Cynthia Hawkins, and Abhijit Guha,
J. Exp. Med., Apr 2011; 208: 689 - 702
[GATA4]
|
|
GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system
,Agnihotri S, Wolf A, Picard D, Hawkins C, Guha A.,
Oncogene. 2009 Jun 22.
[GATA4]
|
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210945 | GATA4 (Myc-DDK-tagged)-Human GATA binding protein 4 (GATA4) |
CNY 3,656.00 |
|
| RC210945L1 | Lenti ORF clone of Human GATA binding protein 4 (GATA4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210945L2 | Lenti ORF clone of Human GATA binding protein 4 (GATA4), mGFP tagged |
CNY 6,056.00 |
|
| RC210945L3 | Lenti ORF clone of Human GATA binding protein 4 (GATA4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210945L4 | Lenti ORF clone of Human GATA binding protein 4 (GATA4), mGFP tagged |
CNY 6,056.00 |
|
| RG210945 | GATA4 (tGFP-tagged) - Human GATA binding protein 4 (GATA4) |
CNY 5,256.00 |
