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alpha 2C Adrenergic Receptor (ADRA2C) (NM_000683) Human Untagged Clone
CAT＃: SC124091
ADRA2C (untagged)-Human adrenergic, alpha-2C-, receptor (ADRA2C)
CNY 5,488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124091 sequence for NM_000683 edited (data generated by NextGen Sequencing)
ATGGCGTCCCCGGCGCTGGCGGCGGCGCTGGCGGTGGCGGCAGCGGCGGGCCCCAATGCG AGCGGCGCGGGCGAGAGGGGCAGCGGCGGGGTTGCCAATGCCTCGGGGGCTTCCTGGGGG CCGCCGCGCGGCCAGTACTCGGCGGGCGCGGTGGCAGGGCTGGCTGCCGTGGTGGGCTTC CTCATCGTCTTCACCGTGGTGGGCAACGTGCTGGTGGTGATCGCCGTGCTGACCAGCCGG GCGCTGCGCGCGCCACAGAACCTCTTCCTGGTGTCGCTGGCCTCGGCCGACATCCTGGTG GCCACGCTGGTCATGCCCTTCTCGTTGGCCAACGAGCTCATGGCCTACTGGTACTTCGGG CAGGTGTGGTGCGGCGTGTACCTGGCGCTCGATGTGCTGTTTTGCACCTCGTCGATCGTG CATCTGTGTGCCATCAGCCTGGACCGCTACTGGTCGGTGACGCAGGCCGTCGAGTACAAC CTGAAGCGCACACCACGCCGCGTCAAGGCCACCATCGTGGCCGTGTGGCTCATCTCGGCC GTCATCTCCTTCCCGCCGCTGGTCTCGCTCTACCGCCAGCCCGACGGCGCCGCCTACCCG CAGTGCGGCCTCAACGACGAGACCTGGTACATCCTGTCCTCCTGCATCGGCTCCTTCTTC GCGCCCTGCCTCATCATGGGCCTGGTCTACGCGCGCATCTACCGAGTGGCCAAGCTGCGC ACGCGCACGCTCAGCGAGAAGCGCGCCCCCGTGGGCCCCGACGGTGCGTCCCCGACTACC GAAAACGGGCTGGGCGCGGCGGCAGGCGCAGGCGAGAACGGGCACTGCGCGCCCCCGCCC GCCGACGTGGAGCCGGACGAGAGCAGCGCAGCGGCCGAGAGGCGGCGGCGCCGGGGCGCG TTGCGGCGGGGCGGGCGGCGGCGAGCGGGCGCCGAGGGGGGCGCGGGCGGTGCGGACGGG CAGGGGGNNGGGCAGGGGGCGGCTGAGTCGGGGGCGCTGACCGCCTCCAGGTCCTCGGGG CCCGGTGGCCGCCTGTCGCGCGCCAGCTCGCGCTCCGTCGAGTTCTTCCTGTCGCGCCGG CGCCGGGCGCGCAGCAGCGTGTGCCGCCGCAAGGTGGCCCAGGCGCGCGAGAAGCGCTTC ACCTTTGTGCTGGCTGTGGTCATGGGTGTGTTCGTGCTCTGCTGGTTCCCCTTCTTCTTC AGCTACAGCCTGTACGGCATCTGCCGCGAGGCCTGCCAGGTGCCCGGCCCGCTCTTCAAG TTCTTCTTCTGGATCGGCTACTGCAACAGCTCGCTCAACCCGGTCATCTACACGGTCTTC AACCAGGATTTCCGGCGATCCTTTAAGCACATCCTCTTCCGACGGAGGAGAAGGGGCTTC AGGCAGTGA Clone variation with respect to NM_000683.3 933 g=>c;968 c=>n;969 g=>n;974 c=>a;1015 c=>t;1167 c=>t >OriGene 5' read for NM_000683 unedited
TTTTTTTGAGGCTATAGGGCGGCCGCGAATTCGCCCTTCCGCGGGAGGACCATGGCGTCC CCGGCGCTGGCGGCGGCGCTGGCGGTGGCGGCAGCGGCGGGCCCCAATGCGAGCGGCGCG GGCGAGAGGGGCAGCGGCGGGGTTGCCAATGCCTCGGGGGCTTCCTGGGGGCCGCCGCGC GGCCAGTACTCGGCGGGCGCGGTGGCAGGGCTGGCTGCCGTGGTGGGCTTCCTCATCGTC TTCACCGTGGTGGGCAACGTGCTGGTGGTGATCGCCGTGCTGACCAGCCGGGCGCTGCGC GCGCCACAGAACCTCTTCCTGGTGTCGCTGGCCTCGGCCGACATCCTGGTGGCCACGCTG GTCATGCCCTTCTCGTTGGCCCAACGAGCTCATGGCCTACTGGTACTTCGGGCAGGTGTG GTGCGGCGTGTACCTGGCGCTCGATGTGCTGTTTTGCACCTCGTCGATCGTGCATCTGTG TGCCATCAGCCTGGACCGCTACTGGTCGGTGACGCANGCCGTCGAGTACAACCTGAAGCG CACACCACGCCGCGTCAAGGCCACCATCGTGGCCGTGTGGCTCATCTCGGCCGTCATCTC CTTCCCGCCGCTGGTCTCGCTCTACCGCCAGCCCGACGGCGCCGCCTACCCGCAGTGCGG CCTCAACGACGAGACCTGGTACATCCTGTCCTCCTGCATCGGCTCCTTCTTCGCGCCCTG CCTCATCATGGGCCTGGTCTACGCGCGCATCTACCGAGTGGN >OriGene 3' read for NM_000683 unedited
AACTTCCAGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTT CAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTTTTTTTTTTTTTAAAATACCAAGG GTTAATTAAAAAATAATTTGGTTGGTTTGGCCGGTGGTTTTGGCAAACATTTAAATACCT TCAGTAATCAAAGAATGGCCGTGCCTTCTCCTTGGCCCCTGGCAGCCACCCCCCGACTAG GTCCCGGAAAAATCAACCCTTGGTCAAACCGGGATGGGGAGTGGTAATGTGTTTTGGGGG CCCCCTGGCTGCCCAATTAAGGGGCCACCTCTGGCACTGGTCTCTAAAACCCTGAACTTA CAACCACCCCTCGGCAAGGGCTCCAAAACTGGATCCCAGCGCGGAACCCCCAAAACCACC CCCTGCTGAAGGGGGAAGGCCAAAGGGTCTTCCCCTCTTTTCTTCCCAATTCCTGGAACC CGGCGATTTCTCTGCCAAACTTCTGGCCTGGCGCAACCTTCCCTGGGCCCTGGAAGCCAA ACCATCCCCCGGTCCTTTGGAGAAGCCCCCCGGTCCCTGGGAAAAGCCCCCCGGTCGGGC CCGCCCTTTCGGCCAACCCCCAAGGCGGAACTTGCCAAAAGATCCAGAAGGGGGGCGAGA CAAGGCCTAAACCCCTTTTCCTCCGGCGAAAAGAGAGTGCCTAAAGAATCCCCGAAAACC CTGTTGAAAACCGGGTAAAGAACCGGTTGAACAAACTGTCCAAC |
| Restriction Sites | Please inquire |
| ACCN | NM_000683 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000683.3, NP_000674.2 |
| RefSeq Size | 1958 bp |
| RefSeq ORF | 1389 bp |
| Locus ID | 152 |
| UniProt ID | P18825 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216418 | ADRA2C (Myc-DDK-tagged)-Human adrenergic, alpha-2C-, receptor (ADRA2C) |
CNY 5,488.00 |
|
| RC216418L1 | Lenti ORF clone of Human adrenergic, alpha-2C-, receptor (ADRA2C), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC216418L2 | Lenti ORF clone of Human adrenergic, alpha-2C-, receptor (ADRA2C), mGFP tagged |
CNY 6,560.00 |
|
| RC216418L3 | Lenti ORF clone of Human adrenergic, alpha-2C-, receptor (ADRA2C), Myc-DDK-tagged |
CNY 6,560.00 |
|
| RC216418L4 | Lenti ORF clone of Human adrenergic, alpha-2C-, receptor (ADRA2C), mGFP tagged |
CNY 6,560.00 |
|
| RG216418 | ADRA2C (tGFP-tagged) - Human adrenergic, alpha-2C-, receptor (ADRA2C) |
CNY 7,088.00 |
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