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FLT4 (NM_182925) Human Untagged Clone
CAT＃: SC124114
FLT4 (untagged)-Human fms-related tyrosine kinase 4 (FLT4), transcript variant 1
CNY 14,000.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CHTD7; FLT-4; FLT41; LMPH1A; LMPHM1; PCL; VEGFR-3; VEGFR3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_182925 edited
GTCGGACCCACGCGCAGCGGCCGGAGATGCAGCGGGGCGCCGCGCTGTGCCTGCGACTGT GGCTCTGCCTGGGACTCCTGGACGGCCTGGTGAGTGGCTACTCCATGACCCCCCCGACCT TGAACATCACGGAGGAGTCACACGTCATCGACACCGGTGACAGCCTGTCCATCTCCTGCA GGGGACAGCACCCCCTCGAGTGGGCTTGGCCAGGAGCTCAGGAGGCGCCAGCCACCGGAG ACAAGGACAGCGAGGACACGGGGGTGGTGCGAGACTGCGAGGGCACAGACGCCAGGCCCT ACTGCAAGGTGTTGCTGCTGCACGAGGTACATGCCAACGACACAGGCAGCTACGTCTGCT ACTACAAGTACATCAAGGCACGCATCGAGGGCACCACGGCCGCCAGCTCCTACGTGTTCG TGAGAGACTTTGAGCAGCCATTCATCAACAAGCCTGACACGCTCTTGGTCAACAGGAAGG ACGCCATGTGGGTGCCCTGTCTGGTGTCCATCCCCGGCCTCAATGTCACGCTGCGCTCGC AAAGCTCGGTGCTGTGGCCAGACGGGCAGGAGGTGGTGTGGGATGACCGGCGGGGCATGC TCGTGTCCACGCCACTGCTGCACGATGCCCTGTACCTGCAGTGCGAGACCACCTGGGGAG ACCAGGACTTCCTTTCCAACCCCTTCCTGGTGCACATCACAGGCAACGAGCTCTATGACA TCCAGCTGTTGCCCAGGAAGTCGCTGGAGCTGCTGGTAGGGGAGAAGCTGGTCCTGAACT GCACCGTGTGGGCTGAGTTTAACTCAGGTGTCACCTTTGACTGGGACTACCCAGGGAAGC AGGCAGAGCGGGGTAAGTGGGTGCCCGAGCGACGCTCCCAGCAGACCCACACAGAACTCT CCAGCATCCTGACCATCCACAACGTCAGCCAGCACGACCTGGGCTCGTATGTGTGCAAGG CCAACAACGGCATCCAGCGATTTCGGGAGAGCACCGAGGTCATTGTGCATGAAAATCCCT TCATCAGCGTCGAGTGGCTCAAAGGACCCATCCTGGAGGCCACGGCAGGAGACGAGCTGG TGAAGCTGCCCGTGAAGCTGGCAGCGTACCCCCCGCCCGAGTTCCAGTGGTACAAGGATG GAAAGGCACTGTCCGGGCGCCACAGTCCACATGCCCTGGTGCTCAAGGAGGTGACAGAGG CCAGCACAGGCACCTACACCCTCGCCCTGTGGAACTCCGCTGCTGGCCTGAGGCGCAACA TCAGCCTGGAGCTGGTGGTGAATGTGCCCCCCCAGATACATGAGAAGGAGGCCTCCTCCC CCAGCATCTACTCGCGTCACAGCCGCCAGGCCCTCACCTGCACGGCCTACGGGGTGCCCC TGCCTCTCAGCATCCAGTGGCACTGGCGGCCCTGGACACCCTGCAAGATGTTTGCCCAGC GTAGTCTCCGGCGGCGGCAGCAGCAAGACCTCATGCCACAGTGCCGTGACTGGAGGGCGG TGACCACGCAGGATGCCGTGAACCCCATCGAGAGCCTGGACACCTGGACCGAGTTTGTGG AGGGAAAGAATAAGACTGTGAGCAAGCTGGTGATCCAGAATGCCAACGTGTCTGCCATGT ACAAGTGTGTGGTCTCCAACAAGGTGGGCCAGGATGAGCGGCTCATCTACTTCTATGTGA CCACCATCCCCGACGGCTTCACCATCGAATCCAAGCCATCCGAGGAGCTACTAGAGGGCC AGCCGGTGCTCCTGAGCTGCCAAGCCGACAGCTACAAGTACGAGCATCTGCGCTGGTACC GCCTCAACCTGTCCACGCTGCACGATGCGCACGGGAACCCGCTTCTGCTCGACTGCAAGA ACGTGCATCTGTTCGCCACCCCTCTGGCCGCCAGCCTGGAGGAGGTGGCACCTGGGGCGC GCCACGCCACGCTCAGCCTGAGTATCCCCCGCGTCGCGCCCGAGCACGAGGGCCACTATG TGTGCGAAGTGCAAGACCGGCGCAGCCATGACAAGCACTGCCACAAGAAGTACCTGTCGG TGCAGGCCCTGGAAGCCCCTCGGCTCACGCAGAACTTGACCGACCTCCTGGTGAACGTGA GCGACTCGCTGGAGATGCAGTGCTTGGTGGCCGGAGCGCACGCGCCCAGCATCGTGTGGT ACAAAGACGAGAGGCTGCTGGAGGAAAAGTCTGGAGTCGACTTGGCGGACTCCAACCAGA AGCTGAGCATCCAGCGCGTGCGCGAGGAGGATGCGGGACGCTATCTGTGCAGCGTGTGCA ACGCCAAGGGCTGCGTCAACTCCTCCGCCAGCGTGGCCGTGGAAGGCTCCGAGGATAAGG GCAGCATGGAGATCGTGATCCTTGTCGGTACCGGCGTCATCGCTGTCTTCTTCTGGGTCC TCCTCCTCCTCATCTTCTGTAACATGAGGAGGCCGGCCCACGCAGACATCAAGACGGGCT ACCTGTCCATCATCATGGACCCCGGGGAGGTGCCTCTGGAGGAGCAATGCGAATACCTGT CCTACGATGCCAGCCAGTGGGAATTCCCCCGAGAGCGGCTGCACCTGGGGAGAGTGCTCG GCTACGGCGCCTTCGGGAAGGTGGTGGAAGCCTCCGCTTTCGGCATCCACAAGGGCAGCA GCTGTGACACCGTGGCCGTGAAAATGCTGAAAGAGGGCGCCACGGCCAGCGAGCACCGCG CGCTGATGTCGGAGCTCAAGATCCTCATTCACATCGGCAACCACCTCAACGTGGTCAACC TCCTCGGGGCGTGCACCAAGCCGCAGGGCCCCCTCATGGTGATCGTGGAGTTCTGCAAGT ACGGCAACCTCTCCAACTTCCTGCGCGCCAAGCGGGACGCCTTCAGCCCCTGCGCGGAGA AGTCTCCCGAGCAGCGCGGACGCTTCCGCGCCATGGTGGAGCTCGCCAGGCTGGATCGGA GGCGGCCGGGGAGCAGCGACAGGGTCCTCTTCGCGCGGTTCTCGAAGACCGAGGGCGGAG CGAGGCGGGCTTCTCCAGACCAAGAAGCTGAGGACCTGTGGCTGAGCCCGCTGACCATGG AAGATCTTGTCTGCTACAGCTTCCAGGTGGCCAGAGGGATGGAGTTCCTGGCTTCCCGAA AGTGCATCCACAGAGACCTGGCTGCTCGGAACATTCTGCTGTCGGAAAGCGACGTGGTGA AGATCTGTGACTTTGGCCTTGCCCGGGACATCTACAAAGACCCTGACTACGTCCGCAAGG GCAGTGCCCGGCTGCCCCTGAAGTGGATGGCCCCTGAAAGCATCTTCGACAAGGTGTACA CCACGCAGAGTGACGTGTGGTCCTTTGGGGTGCTTCTCTGGGAGATCTTCTCTCTGGGGG CCTCCCCGTACCCTGGGGTGCAGATCAATGAGGAGTTCTGCCAGCGGCTGAGAGACGGCA CAAGGATGAGGGCCCCGGAGCTGGCCACTCCCGCCATACGCCGCATCATGCTGAACTGCT GGTCCGGAGACCCCAAGGCGAGACCTGCATTCTCGGAGCTGGTGGAGATCCTGGGGGACC TGCTCCAGGGCAGGGGCCTGCAAGAGGAAGAGGAGGTCTGCATGGCCCCGCGCAGCTCTC AGAGCTCAGAAGAGGGCAGCTTCTCGCAGGTGTCCACCATGGCCCTACACATCGCCCAGG CTGACGCTGAGGACAGCCCGCCAAGCCTGCAGCGCCACAGCCTGGCCGCCAGGTATTACA ACTGGGTGTCCTTTCCCGGGTGCCTGGCCAGAGGGGCTGAGACCCGTGGTTCCTCCAGGA TGAAGACATTTGAGGAATTCCCCATGACCCCAACGACCTACAAAGGCTCTGTGGACAACC AGACAGACAGTGGGATGGTGCTGGCCTCGGAGGAGTTTGAGCAGATAGAGAGCAGGCATA GACAAGAAAGCGGCTTCAGCTGTAAAGGACCTGGCCAGAATGTGGCTGTGACCAGGGCAC ACCCTGACTCCCAAGGGAGGCGGCGGCGGCCTGAGCGGGGGGCCCGAGGAGGCCAGGTGT TTTACAACAGCGAGTATGGGGAGCTGTCGGAGCCAAGCGAGGAGGACCACTGCTCCCCGT CTGCCCGCGTGACTTTCTTCACAGACAACAGCTACTAAGCAGCATCGGACAAGACCCCCA GCACTTGGGGGTTCAGGCCCGGCAGGGCGGGCAGAGGGCTGGAGGCCCAGGCTGGGAACT CATCTGGTTGAACTCTGGTGGCACAGGAGTGTCCTCTTCCCTCTCTGCAGACTTCCCAGC TAGGAAGAGCAGGACTCCAGGCCCAAGGCTCCCGGAATTCCGTCACCACGACTGGCCAGG GCCACGCTCCAGCTGCCCCGGCCCCTCCCCCTGAGATTCAGATGTCATTTAGTTCAGCAT CCGCAGGTGCTGGTCCCGGGGCCAGCACTTCCATGGGAATGTCTCTTTGGCGACCTCCTT TCATCACACTGGGTGGTGGCCTGGTCCCTGTTTTCCCACGAGGAATCTGTGGGTCTGGGA GTCACACAGTGTTGGAGGTTAAGGCATACGAGAGCAGAGGTCTCCCAAACGCCCTTTCCT CCTCAGGCACACAGCTACTCTCCCCACGAGGGCTGGCTGGCCTCACCCACCCCTGCACAG TTGAAGGGAGGGGCTGTGTTTCCATCTCAAAGAAGGCATTTGCAGGGTCCTCTTCTGGGC CTGACCAAACAGCCAACTAGC >OriGene 3' read for NM_182925 unedited
CAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGC TATGACCGTGGCCGCAATCTAGACTCAGTACAGCTGTCCCTGGGCGCCTTCCAGGCTGAA TTCGGAAAGCAAATTCTTCTCAGCAGCTCTAACAGTCTGTGAAGTTCTGTTGAAAAAGAC TTGCAGGATGGCTCTCAACACCCAGGCGCAGGTGTGCGGGCTGCCTCTGTGTTGCCAGCG TATAATACTGTCATACTGGTGGCCACCCCAGGGGCTAGTTGGCTGTTTGGTCAGGCCCAG AAGAGGACCCTGCAAATGCCTTCTTTGAGATGGAAACACAGCCCCTCCCTTCAACTGTGC AGGGGTGGGTGAGGCCAGCCAGCCCTCGTGGGGAGAGTAGCTGTGTGCCTGAGGAGGAAA GGGCGTTTGGGAGACCTCTGCTCTCGTATGCCTTAACCTCCAACACTGTGTGACTCCCAG ACCCACAGATTCCTCGTGGGAAAACAGGGACCAGGCCACCACCCAGTGTGATGAAAGGAG GTCGCCAAAGAGACATTCCCATGGAAGTGCTGGCCCCGGGACCAGCACCTGCGGATGCTG AACTAAATGACATCTGAATCTCAGGNGGAGGGGCCGGNGCAGCTGGAGCGTGGCCCTGGC CAGTCGTGGTGACGGAATTCCGGGAGNCCTGNGCCTGGAGTCCTGCTCTTCCTAGCTGGG GAGTCTGC |
| Restriction Sites | Please inquire |
| ACCN | NM_182925 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_182925.1, NP_891555.1 |
| RefSeq Size | 5857 bp |
| RefSeq ORF | 4092 bp |
| Locus ID | 2324 |
| UniProt ID | P35916 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Focal adhesion |
| Gene Summary | This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway
,Y Luo, H Zhou, L Liu, T Shen, W Chen, B Xu, X Han, F Zhang, R S Scott, J S Alexander, et al.,
Oncogene (10 January 2011) doi:10.1038/onc.2010.590 Original Article
[Flt4]
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