TBX5 (NM_181486) Human Untagged Clone
CAT#: SC124969
TBX5 (untagged)-Human T-box 5 (TBX5), transcript variant 4
CNY 7,220.00
Cited in 1 publication. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HOS |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_181486, the custom clone sequence may differ by one or more nucleotides
ATGGCCGACGCAGACGAGGGCTTTGGCCTGGCGCACACGCCTCTGGAGCCTGACGCAAAAGACCTGCCCT GCGATTCGAAACCCGAGAGCGCGCTCGGGGCCCCCAGCAAGTCCCCGTCGTCCCCGCAGGCCGCCTTCAC CCAGCAGGGCATGGAGGGAATCAAAGTGTTTCTCCATGAAAGAGAACTGTGGCTAAAATTCCACGAAGTG GGCACGGAAATGATCATAACCAAGGCTGGAAGGCGGATGTTTCCCAGTTACAAAGTGAAGGTGACGGGCC TTAATCCCAAAACGAAGTACATTCTTCTCATGGACATTGTACCTGCCGACGATCACAGATACAAATTCGC AGATAATAAATGGTCTGTGACGGGCAAAGCTGAGCCCGCCATGCCTGGCCGCCTGTACGTGCACCCAGAC TCCCCCGCCACCGGGGCGCATTGGATGAGGCAGCTCGTCTCCTTCCAGAAACTCAAGCTCACCAACAACC ACCTGGACCCATTTGGGCATATTATTCTAAATTCCATGCACAAATACCAGCCTAGATTACACATCGTGAA AGCGGATGAAAATAATGGATTTGGCTCAAAAAATACAGCGTTCTGCACTCACGTCTTTCCTGAGACTGCG TTTATAGCAGTGACTTCCTACCAGAACCACAAGATCACGCAATTAAAGATTGAGAATAATCCCTTTGCCA AAGGATTTCGGGGCAGTGATGACATGGAGCTGCACAGAATGTCAAGAATGCAAAGTAAAGAATATCCCGT GGTCCCCAGGAGCACCGTGAGGCAAAAAGTGGCCTCCAACCACAGTCCTTTCAGCAGCGAGTCTCGAGCT CTCTCCACCTCATCCAATTTGGGGTCCCAATACCAGTGTGAGAATGGTGTTTCCGGCCCCTCCCAGGACC TCCTGCCTCCACCCAACCCATACCCACTGCCCCAGGAGCATAGCCAAATTTACCATTGTACCAAGAGGAA AGAGGAAGAATGTTCCACCACAGACCATCCCTATAAGAAGCCCTACATGGAGACATCACCCAGTGAAGAA GATTCCTTCTACCGCTCTAGCTATCCACAGCAGCAGGGCCTGGGTGCCTCCTACAGGACAGAGTCGGCAC AGCGGCAAGCTTGCATGTATGCCAGCTCTGCGCCCCCCAGCGAGCCTGTGCCCAGCCTAGAGGACATCAG CTGCAACACGTGGCCAAGCATGCCTTCCTACAGCAGCTGCACCGTCACCACCGTGCAGCCCATGGACAGG CTACCCTACCAGCACTTCTCCGCTCACTTCACCTCGGGGCCCCTGGTCCCTCGGCTGGCTGGCATGGCCA ACCATGGCTCCCCACAGCTGGGAGAGGGAATGTTCCAGCACCAGACCTCCGTGGCCCACCAGCCTGTGGT CAGGCAGTGTGGGCCTCAGACTGGCCTGCAGTCCCCTGGCACCCTTCAGCCCCCTGAGTTCCTCTACTCT CATGGCGTGCCAAGGACTCTATCCCCTCATCAGTACCACTCTGTGCACGGAGTTGGCATGGTGCCAGAGT GGAGCGACAATAGCTAA >OriGene 5' read for NM_181486 unedited
NGGTTCACAATTGTAAACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGAGTTG GCTTGTATTTCAGAGAGAGAGAGAGAGGGAGAGAGAGTGAGAGAGACTGACTCTTACCTC GAATCCGGGAACTTTAATCCTGAAAGCTGCGCTCAGAAAGGACTTCGACCATTCACTGGG CTTCCAACTTTCCCTCCCTGGGGGTGTAAAGGAGGAGCGGGGCACTGAGATTATATGGTT GCCGGTGCTCTTGGAGGCTATTTTGTGTTCTTTGGCGCTTGCCAACTGGGAAGTATTTAG GGAGAGCAAGCGCACAGCAGAGGAGGTGTGTGTTGGAGGTGGGCAGTCGCCGCGGAGGCT CCAGCGGTAGGTGCGCCCTAGTAGGCAGCAGTAGCCGCTATTCTGGGTAAGCAGTAAACC CCGCATAAACCCCGGAGCCACCATGCCTGCTCCCCCGCCTCACCGCCGGCTTCCCTGCTA GGAGCAGCAGAGGATGTGGTGAATGCACCGGCTTCACCGAACGAGAGCAGAACCTTGCGC GGGCACAGGGCCCTGGGCGCACCATGGCCGACGCAGACGAGGGCTTTGGCCTGGCGCACA CGCCTCTGGAGCCTGACGCAAAAGACCTGCCCTGCGATTCGAAACCCGAGAGCGCGCTCG GNGCCCCCAGCAAGTCCCCGTCGTCCCCGCAGGCCGCCTTCACCCAGCAGGGCATGGAGG GAATCAAAGTGTTTCTCCATGAAAGAGAACTGTGGCTAANATTCCACGAAGTGGGCACGG AAATGATCATAAACCAAGCTGGAAGGCNGATGTTTCCCAGTTACAAAGTGAAGGTGACGG GCCTTAATCCCAAACGAATACATTCTTCTCATGGACATTGTACCTGCCGACGACACAGAT ACAATCGCAGATATAATGGTCTGTGACGGNCAAGCTGAGCCGCCATGCT |
Restriction Sites | NotI-NotI |
ACCN | NM_181486 |
Insert Size | 2550 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_181486.1, NP_852259.1 |
RefSeq Size | 3749 bp |
RefSeq ORF | 1557 bp |
Locus ID | 6910 |
UniProt ID | Q99593 |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 and 4 both encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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TBX5 mutations contribute to early-onset atrial fibrillation in Chinese and Caucasians
,Ma, JF;Yang, F;Mahida, SN;Zhao, L;Chen, X;Zhang, ML;Sun, Z;Yao, Y;Zhang, YX;Zheng, GY;Dong, J;Feng, MJ;Zhang, R;Sun, J;Li, S;Wang, QS;Cao, H;Benjamin, EJ;Ellinor, PT;Li, YG;Tian, XL;,
Cardiovasc. Res.
,PubMed ID 26762269
[TBX5]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC221808 | TBX5 (Myc-DDK-tagged)-Human T-box 5 (TBX5), transcript variant 4 |
CNY 3,856.00 |
|
RC221808L3 | Lenti ORF clone of Human T-box 5 (TBX5), transcript variant 4, Myc-DDK-tagged |
CNY 5,890.00 |
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RC221808L4 | Lenti ORF clone of Human T-box 5 (TBX5), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
RG221808 | TBX5 (tGFP-tagged) - Human T-box 5 (TBX5), transcript variant 4 |
CNY 5,456.00 |