IL6 (NM_000600) Human Untagged Clone

CAT#: SC125236

IL6 (untagged)-Human interleukin 6 (interferon, beta 2) (IL6)



  "NM_000600" in other vectors (6)

CNY 2,400.00

CNY 3,990.00


货期*
现货

规格
    • 10 ug

Cited in 5 publications.

Product images

经常一起买 (4)
IL6 mouse monoclonal antibody, clone OTI3G9 (formerly 3G9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC125236 sequence for NM_000600 edited (data generated by NextGen Sequencing)
ATGAACTCCTTCTCCACAAGCGCCTTCGGTCCAGTTGCCTTCTCCCTGGGGCTGCTCCTG
GTGTTGCCTGCTGCCTTCCCTGCCCCAGTACCCCCAGGAGAAGATTCCAAAGATGTAGCC
GCCCCACACAGACAGCCACTCACCTCTTCAGAACGAATTGACAAACAAATTCGGTACATC
CTCGACGGCATCTCAGCCCTGAGAAAGGAGACATGTAACAAGAGTAACATGTGTGAAAGC
AGCAAAGAGGCACTGGCAGAAAACAACCTGAACCTTCCAAAGATGGCTGAAAAAGATGGA
TGCTTCCAATCTGGATTCAATGAGGAGACTTGCCTGGTGAAAATCATCACTGGTCTTTTG
GAGTTTGAGGTATACCTAGAGTACCTCCAGAACAGATTTGAGAGTAGTGAGGAACAAGCC
AGAGCTGTGCAGATGAGTACAAAAGTCCTGATCCAGTTCCTGCAGAAAAAGGCAAAGAAT
CTAGATGCAATAACCACCCCTGACCCAACCACAAATGCCAGCCTGCTGACGAAGCTGCAG
GCACAGAACCAGTGGCTGCAGGACATGACAACTCATCTCATTCTGCGCAGCTTTAAGGAG
TTCCTGCAGTCCAGCCTGAGGGCTCTTCGGCAAATGTAG

Clone variation with respect to NM_000600.3
>OriGene 5' read for NM_000600 unedited
GACTCACTATAGGGCGGCCGCGAATTCAGCCCAGCTATGAACTCCTTCTCCACAAGCGCC
TTCGGTCCAGTTGCCTTCTCCCTGGGGCTGCTCCTGGTGTTGCCTGCTGCCTTCCCTGCC
CCAGTACCCCCAGGAGAAGATTCCAAAGATGTAGCCGCCCCACACAGACAGCCACTCACC
TCTTCAGAACGAATTGACAAACAAATTCGGTACATCCTCGACGGCATCTCAGCCCTGAGA
AAGGAGACATGTAACAAGAGTAACATGTGTGAAAGCAGCAAAGAGGCACTGGCAGAAAAC
AACCTGAACCTTCCAAAGATGGCTGAAAAAGATGGATGCTTCCAATCTGGATTCAATGAG
GAGACTTGCCTGGTGAAAATCATCACTGGTCTTTTGGAGTTTGAGGTATACCTAGAGTAC
CTCCAGAACAGATTTGAGAGTAGTGAGGAACAAGCCAGAGCTGTGCAGATGAGTACAAAA
GTCCTGATCCAGTTCCTGCAGAAAAAGGCAAAGAATCTAGATGCAATAACCACCCCTGAC
CCAACCACAAATGCCAGCCTGCTGACGAAGCTGCAGGCACAGAACCAGTGGCTGCAGGAC
TTGACAACTTATCTCATTCTGCGCAGCTTTAGGAGTTCCGGAGTTCACCTGAGGGCTTTC
GGAAAAGTACATGGGCACTCATTCTTGATTTTGTTGGGGGCGCGGAATATTTTTCCTAAA
AATCCGGGGGGCTCTGGGACCCTCCCAGGGTTTTGGGCCA
>OriGene 3' read for NM_000600 unedited
NCCCCTCCATTGCGCAATTGGCGAAGGCCAATTTCCAGGGCCAGNACGAGCACTGGGGNA
GGGTTCACAGGGCATGCCCCCGGGCACTGTTCAGGAAACAGCTATGACCGCGGCCGCAAT
CTAGAGTCGAGATCTGAGGTGCCCATGCTTACATTTGCCGAAGAGCCCTCAGGCTGGACT
GCAGGAACTCCTTAAAGCTGCGCAGAATGAGATGAGTTGTCATGTCCTGCAGCCACTGGT
TCTGTGCCTGCAGCTTCGTCAGCAGGCTGGCATTTGTGGTTGGGTCAGGGGTGGTTATTG
CATCTAGATTCTTTGCCTTTTTCTGCAGGAACTGGATCAGGACTTTTGTACTCATCTGCA
CAGCTCTGGCTTGTTCCTCACTACTCTCAAATCTGTTCTGGAGGTACTCTAGGTATACCT
CANACTCCAAAAGACCAGTGATGATTTTCACCAGGCAAGTCTCCTCATTGAATCCAGATT
GGAAGCATCCATCTTTTTCAGCCATCTTTGGAAGGTTCAGGTTGTTTTCTGCCAGTGCCT
CTTTGCTGCTTTCACACATGTTACTCTTGTTACATGTCTCCTTTCTCAGGGCTGAGATGC
CGTCGAGGATGTACCGAATTTGTTTGTCAATTCGTTCTGAAGAGGTGAGTGGCTGTCTGT
GTGGNGCGGCTACATCTTTGGAATCTTCTCCTGGGGGTACTGGGGCAGGGAAGGCAGCAG
GCAACACCAGNAGCAGCCCCAGGGGAGAAGCAACTGGACCCGAAGCGCTTGTGGAGAANG
AGTTCATAGCTGGGCTGAATTCGCCGCCGCCTATAGTGAGTCGTATACAAAATTCTGACG
TTCACTAACGAGCTTTGCTATTTAGACCTCCNACGTACACGCCTACCGCCAT
Restriction Sites Please inquire     
ACCN NM_000600
Insert Size 639 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000600.1, NP_000591.1
RefSeq Size 1125 bp
RefSeq ORF 639 bp
Locus ID 3569
UniProt ID P05231
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Jak-STAT signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prion diseases, Toll-like receptor signaling pathway
Gene Summary This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (5)

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