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Oct4 (POU5F1) (NM_002701) Human Untagged Clone
CAT＃: SC125252
POU5F1/OCT4 (untagged)-Human POU class 5 homeobox 1 (POU5F1/OCT4), transcript variant 1
CNY 3,656.00
CNY 7,220.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002701 edited
CTGCGGGGTGGCTGGATTTGGCCAGTATCGGGATGGGAATGCCTAGGATTCTGGATGGAT CGGGGGAAGGCATAAGGGAGCAGCTGGCCATTGTGCTTATGGCTGTTGATGCATTGAGGG ATAGCGCCACACACACATTCAATAAATTTGAGGAGCTGAGAGGGTGACTGGCCCCTGAAG GCACAGTGCCAGAGGTCTGTGGAGAGGGGGTCAAGCACCTGGGTTCCTGAAGAACATGGA GGTGTGGGAGTGATTCCAGACAGCTGGGATGTGCAGAGCCTGAGAGAGTGCCAGGGAGCG GGTTGGGAGTTGAAAGTTGGGTGTGGTGGCTCACGCCTTTAATCATGACACTGGGCGGCA GAGGCGGGAGGATTTCTTGAGGACAGGAATTCAAGACCAGCCTGGGTAACATAGCAAGGC CCCATCTCTACTAAAAATAAAAAAACTAACAGGGCACAGTGGTCCAAGCCTGTAGTCCCA GCCACTTAGGAGGCTGGAGCAGAAGGATTGCTTTGGCCCAGTAGATCGAGGCTACATTGA GCCATCATTGTACTCCACTGCACTCCAGTCTGGGCAACAAAGTGAGACCCTGTCTTAAAA AATAAAAATAAAAAAAGTTTCTGTGGGGGACCTGCACTGAGGTCCTGGAGGGGCGCCAGT TGTGTCTCCCGGTTTTCCCCTTCCACAGACACCATTGCCACCACCATTAGGCAAACATCC TTCGCCTCAGTTTCTCCCCCCACCTCCCTCTCCTCCACCCATCCAGGGGGCGGGGCCAGA GGTCAAGGCTAGTGGGTGGGACTGGGGAGGGAGAGAGGGGTTGAGTAGTCCCTTCGCAAG CCCTCATTTCACCAGGCCCCCGGCTTGGGGCGCCTTCCTTCCCCATGGCGGGACACCTGG CTTCGGATTTCGCCTTCTCGCCCCCTCCAGGTGGTGGAGGTGATGGGCCAGGGGGGCCGG AGCCGGGCTGGGTTGATCCTCGGACCTGGCTAAGCTTCCAAGGCCCTCCTGGAGGGCCAG GAATCGGGCCGGGGGTTGGGCCAGGCTCTGAGGTGTGGGGGATTCCCCCATGCCCCCCGC CGTATGAGTTCTGTGGGGGGATGGCGTACTGTGGGCCCCAGGTTGGAGTGGGGCTAGTGC CCCAAGGCGGCTTGGAGACCTCTCAGCCTGAGGGCGAAGCAGGAGTCGGGGTGGAGAGCA ACTCCGATGGGGCCTCCCCGGAGCCCTGCACCGTCACCCCTGGTGCCGTGAAGCTGGAGA AGGAGAAGCTGGAGCAAAACCCGGAGGAGTCCCAGGACATCAAAGCTCTGCAGAAAGAAC TCGAGCAATTTGCCAAGCTCCTGAAGCAGAAGAGGATCACCCTGGGATATACACAGGCCG ATGTGGGGCTCACCCTGGGGGTTCTATTTGGGAAGGTATTCAGCCAAACGACCATCTGCC GCTTTGAGGCTCTGCAGCTTAGCTTCAAGAACATGTGTAAGCTGCGGCCCTTGCTGCAGA AGTGGGTGGAGGAAGCTGACAACAATGAAAATCTTCAGGAGATATGCAAAGCAGAAACCC TCGTGCAGGCCCGAAAGAGAAAGCGAACCAGTATCGAGAACCGAGTGAGAGGCAACCTGG AGAATTTGTTCCTGCAGTGCCCGAAACCGACACTGCAGCAGATCAGCCACATCGCCCAGC AGCTTGGGCTCGAGAAGGATGTGGTCCGAGTGTGGTTCTGTAACCGGCGCCAGAAGGGCA AGCGATCAAGCAGCGACTATGCACAACGAGAGGATTTTGAGGCTGCTGGGTCTCCTTTCT CAGGGGGACCAGTGTCCTTTCCTCTGGCCCCAGGGCCCCATTTTGGTACCCCAGGCTATG GGAGCCCTCACTTCACTGCACTGTACTCCTCGGTCCCTTTCCCTGAGGGGGAAGCCTTTC CCCCTGTCTCCGTCACCACTCTGGGCTCTCCCATGCATTCAAACTGAGGTGCCTGCCCTT CTAGGAATGGGGGACAGGGGGAGGGGAGGAGCTAGGGAAAGAAAACCTGGAGTTTGTGCC AGGGTTTTTGGGATTAAGTTCTTCATTCACTAAGGAAGGAATTGGGAACACAAAGGGTGG GGGCAGGGGAGTTTGGGGCAACTGGTTGGAGGGAAGGTGAAGTTCAATGATGCTCTTGAT TTTAATCCCACATCATGTATCACTTTTTTCTTAAATAAAGAAGCCTGGGACACAGTAGAT AGAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' genomic read for NM_002701 unedited
ACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCGGGGTGGCTGGATTTGGCCAGTATC GGGATGGGAATGCCTAGGATTCTGGATGGATCGGGGGAAGGCATAAGGGAGCAGCTGGCC ATTGTGCTTATGGCTGTTGATGCATTGAGGGATAGCGCCACACACACATTCAATAAATTT GAGGAGCTGAGAGGGTGACTGGCCCCTGAAGGCACAGTGCCAGAGGTCTGTGGAGAGGGG GTCAAGCACCTGGGTTCCTGAAGAACATGGAGGTGTGGGAGTGATTCCAGACAGCTGGGA TGTGCAGAGCCTGAGAGAGTGCCAGGGAGCGGGTTGGGAGTTGAAAGTTGGGTGTGGTGG CTCACGCCTTTAATCATGACACTGGGCGGCAGAGGCGGGAGGATTTCTTGAGGACAGGAA TTCAAGACCAGCCTGGGTAACATAGCAAGGCCCCATCTCTACTAAAAATAAAAAAACTAA CAGGGCACAGTGGTCCAAGCCTGTAGTCCCAGCCACTTAGGAGGCTGGAGCAGAAGGATT GCTTTGGCCCAGTAGATCGAGGCTACATTGAGCCATCATTGTACTCCACTGCACTCCAGT CTGGGCAACAAAGTGAGACCCTGTCTTANAAAATAAAAATAAAAAAAGTTTCTGTGGNGG ACCTGCACTGAGGTCCTGGAGGGGCGCCAGTTGTGTCTCCCGGTTTTCCCCTTCCACAGA CACCATTGCCACCACCN >OriGene 3' read for NM_002701 unedited
CCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAG CTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTC TATCTACTGTGTCCCAGGCTTCTTTATTTAAGAAAAAAGTGATACATGATGTGGGATTAA AATCAAGAGCATCATTGAACTTCACCTTCCCTCCAACCAGTTGCCCCAAACTCCCCTGCC CCCACCCTTTGTGTTCCCAATTCCTTCCTTAGTGAATGAAGAACTTAATCCCAAAAACCC TGGCACAAACTCCAGGTTTTCTTTCCCTAGCTCCTCCCCTCCCCCTGTCCCCCATTCCTA GAAGGGCAGGCACCTCAGTTTGAATGCATGGGAGAGCCCAGAGTGGTGACGGAGACAGGG GGAAAGGCTTCCCCCTCAGGGAAAGGGACCGAGGAGTACAGTGCAGTGAAGTGAGGGCTC CCATAGCCTGGGGTACCAAAATGGGGCCCTGGGGCCAGAGGAAAGGACACTGGTCCCCCT GAGAAAGGAGACCCAGCAGCCTCAAAATCCTCTCGTTGTGCATAGTCGCTGCTTGATCGC TTGCCCTTCTGGCGCCGGTTACAGAACCACACTCGGACCACATCCTTCTCGAGCCCAAGC TGCTGGGCGATGTGGCTGATCTGCTGCAGTGTCGGTTTCGGGCACTGCAGGAACAAAATC TCCAGGTTGCCTCTCACTCGN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002701 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002701.3, NP_002692.2 |
| RefSeq Size | 1417 bp |
| RefSeq ORF | 1083 bp |
| Locus ID | 5460 |
| UniProt ID | Q01860 |
| Protein Families | Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors |
| Gene Summary | This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013] Transcript Variant: This variant (1, also known as OCT4A) represents the shortest transcript and encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification of functional amino Acid residues involved in polyamine and agmatine transport by human organic cation transporter 2
,Higashi, K;Imamura, M;Fudo, S;Uemura, T;Saiki, R;Hoshino, T;Toida, T;Kashiwagi, K;Igarashi, K;,
PLoS ONE July 2014
,PubMed ID 25019617
[POU5F1]
|
|
Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
,Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura, and Ken-ichi Inui,
Drug Metab. Dispos., Nov 2008; 36: 2299 - 2306.
[POU5F1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211998 | POU5F1/OCT4 (Myc-DDK-tagged)-Human POU class 5 homeobox 1 (POU5F1/OCT4), transcript variant 1 |
CNY 3,656.00 |
|
| RC211998L1 | Lenti ORF clone of Human POU class 5 homeobox 1 (POU5F1), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC211998L2 | Lenti ORF clone of Human POU class 5 homeobox 1 (POU5F1), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RC211998L3 | Lenti ORF clone of Human POU class 5 homeobox 1 (POU5F1), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC211998L4 | Lenti ORF clone of Human POU class 5 homeobox 1 (POU5F1), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG211998 | POU5F1 (tGFP-tagged) - Human POU class 5 homeobox 1 (POU5F1), transcript variant 1 |
CNY 5,256.00 |
